S00015 Tea polyphenol Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, w
T0001 Ferrous fumarate Iron(II) fumarate, also named as ferrous fumarate, is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake.
T0003 Sodium Nitroprusside Sodium Nitroprusside is a potent vasodilator, releasing in blood with no spontaneously.
T0006 Methylene Blue trihydrate Methylene blue is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene b
T0010 Mercaptopurine Mercaptopurine is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, u
T0011 Phenethyl alcohol Phenethyl alcohol is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
T0013 Mecarbinate Mecarbinate is arbidol hydrochloride's chemical intermediate.
T0014 cis-Anethol Anethole is a type of aromatic compound that exists widely in nature, widely utilized as a seasoning substance.
T0015 Mephenesin Mephenesin is a centrally acting muscle relaxant with a short duration of action.
T0016 Mexenone Mexenone is a benzophenone-derived sun protection.
T0017 Phenolphthalein Phenolphthalein is an acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
T0019 Betaine hydrochloride Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the formation of secon
T0021 Vanatone It is an inhibitor of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)
T0023 Valethamate bromide Valethamate bromide is an anticholinergic agent.
T0027 Octisalate Ethylhexyl salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester f
T0028 4-Amino-3-hydroxybutyric Acid Agent for improving learning or memory [US6803366]Gamma Hydroxybutyric Acid, commonly abbreviated GHB, is an illegal therapeutic drug in multiple countries. In the US, it is curr
T0032 DL-Xylose Xylose is a sugar first derived from wood. Xylose is classified as a monosaccharide of the aldopentose type.
T0037 Halazone Halazone is fine white powder with an odor of chlorine.
T0043 2-Amino-6-methylheptane Octodrine is a stimulant drug,a platinum complex form of which was also investigated as a possible anti-tumor drug.
T0056 Oxeladin citrate Oxeladin is a highly potent and effective cough suppressant,which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment wi
T0066 Dichlorophen Dichlorophen is a nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ing
T0067 Oxiniacic Acid Oxiniacic Acid is a nicotinic acid derivative, used to treat hyperlipoidemia.
T0069 Uracil Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use i
T0071 Homosalate Homosalate is an organic compound used as a chemical UV filter. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol.
T0073 Octyl 4-methoxycinnamate Octinoxate is an organic compound that is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage,primarily as an ingredient in
T0077 Dantrolene sodium salt Dantrolene is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neuromuscu
T0131 Cepharanthine Cepharanthine, a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and i
T0144 Ftaxilide Ftaxilide has antibacterial property, used as antiseptic.
T0148L Folinic Acid Calcium Salt Pentahydrate Folinic Acid, a reduced folic acid, is used in combination with other chemotherapeutics.
T0150 Hydroxyhexamide Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.
T0170 Fosfomycin calcium Fosfomycin calcium is an antibiotic, used for the treatment of urinary tract infections and intestinal infections caused by susceptible strains.
T0176 Aloin It is used as a stimulant-laxative, treating constipation by inducing bowel movements.[2] The compound is present in what is commonly referred to as the aloe latex that exudes from
T0179 Ticagrelor Ticagrelor, produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved f
T0183 Pramiracetam Pramiracetam, derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Prami
T0187 Amorolfine hydrochloride Amorolfine Hydrochloride is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually dis
T0192 Levetiracetam Levetiracetam is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levetiracetam has been li
T0195 Secnidazole Secnidazole is a second-generation 5-nitroimidazole antimicrobial that is structurally related to other 5-nitroimidazoles including [DB00916] and [DB00911], but displays improved o
T0198 Sodium ceftiofur Ceftiofur sodium, an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.
T0200 Thioctic acid Thioctic acid is an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC
T0224 Meropenem Meropenem is a carbapenem antibiotic with broad spectrum of activity that is administered intravenously and used for severe bacterial infections due to sensitive agents. Meropenem
T0227 Bromisoval Bromisoval is a mild hypnotic and sedative with potential toxicity.
T0233 Ethamivan Etamivan (INN) or ethamivan (USAN), is a respiratory stimulant drug concerned with nikethamide. Its trade name is Analepticon, and no longer used in the US.
T0237 Closantel Closantel, a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.
T0238 2-(Acetyloxy)-3-Methylbenzoic Acid 2-(Acetyloxy)-3-Methylbenzoic Acid is used in qHTS Assay for Inhibitors of hydroxysteroid (17-beta) dehydrogenase 4, HSD17B4 with activity value of 19.95 µM
T0239 Lonidamine Lonidamine is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
T0240 Trimetozine Trimetozine is a sedative that has been marketed in Europe since 1959. It has mild tranquilizing effects and has been used to treat anxiety.
T0243 Vanitiolide A choleretic.
T0244 Tilorone dihydrochloride Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
T0251 Gemcitabine Gemcitabine is a DNA synthesis inhibitor that can inhibit the growth of MIAPaCa2, BxPC3 and Capan2 cells (IC50s: 40/18/12 nM). It can also induce autophagy.
T0257 Mepiroxol Mepiroxol, an antihyperlipidemic, is also called 3-PYRIDINEMETHANOL N-OXIDE.
T0258 Carsalame Carsalam is a nonsteroidal anti-inflammatory drug.
T0259 Chromocarbe Chromocarb is a vascular protective agent used to treat venous disorders and microvascular affections.
T0265 Merbromin Merbromin is an organomercuric disodium salt compound and a fluorescein, used as a topical antiseptic for minor cuts and scrapes.
T0271 Iodipamide Iodipamide is a water-soluble radiographic contrast media for intravenous cholangiography and cholecystography.
T0273 Mefexamide hydrochloride Mefexamide hydrochloride is a central stimulant.
T0275 Meticrane Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity.
T0278 Escin Escin is biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of Aesculus.
T0281 Meclocycline sulfosalicylate salt Meclocycline (INN), a tetracycline antibiotic, is used topically (i.e. for skin infections) as it is totally insoluble in water and may damage kidney and liver if given systemicall
T0284 Sulfogaiacol Sulfogaiacol is an antitussive agent, used for acute respiratory tract infections and cough.
T0286 Bephenium Hydroxynaphthoate Bephenium hydroxynaphthoate is a B-type AChR activator, formerly used in the treatment of hookworm infections and ascariasis.
T0288 Procodazole Procodazole is a non-specific active immunoprotective agent against viral and bacterial infections.
T0289 Aminacrine 9-Aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used
T0292 Orbifloxacin Orbifloxacin is a broad-spectrum fluoroquinolone antibiotic.
T0293 Metyrapone Metyrapone is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
T0296 Pempidine Pempidine is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.
T0299 Lactitol monohydrate Lactitol monohydrate is a disaccharide analog of lactulose. It has been widely used to treat constipation & hepatic encephalopathy.
T0306 Undecenoic acid Undecylenic Acid is a natural or synthetic fungistatic fatty acid, with antifungal activity.
T0307 Tyloxapol Tyloxapol is a non-ionic liquid polymer used as a surfactant.
T0308 Etidronate Etidronic is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
T0310 Actarit Actarit is an anti-inflammatory drug.
T0311 Diathesin Diathesin is an intermediate for medicine, perfume, pesticide.
T0312 Blutene chloride Blutene chloride, a phenothiazine, is used as a biological stain, a hemostatic, and a dye for silk and wool. Blutene chloride is also used as a diagnostic aid for gastric neoplasms
T0315 Acedoben Acedoben (4-acetamidobenzoic acid) is the acetyl derivative of para-aminobenzoic acid (PABA).
T0316 Citiolone Citiolone, a drug used in liver treatment, is a derivative of the amino acid cysteine.
T0323 Oxantel Pamoate Oxantel pamoate is used as an Antinematodal agent.
T0325 Diperodon hydrochloride Diperodon is a local anaesthetics.
T0328 Hexetidine Hexetidine is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.
T0332 D-Sorbitol Sorbitol is a polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diur
T0336 Benzalkonium chloride Benzalkonium chloride is a cationic surface-acting agent containing the quaternary ammonium group. It has three main categories of use: as a cationic surfactant, a biocide, and pha
T0340 Bisoctrizole Bisoctrizole is a benzotriazole-based organic compound that is added to sunscreens to absorb UV rays.
T0342 Carvedilol phosphate Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti
T0344L Miconazole nitrate Miconazole nitrate, an imidazole antifungal agent, selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalia
T0346 Camylofin Camylofin is an antimuscarinic, used for relaxing smooth muscle.
T0347 Phenol Red Phenol Red is a pH indicator, red dye, and diagnostic aid for measurement of renal function. It is used also for researches of the gastrointestinal and other systems.
T0352 Dibenzothiophene Dibenzothiophene, a component of petroleum oils, is a sulfur-containing polycyclic aromatic hydrocarbon (PAH) derivate consisting of 3 fused rings with keratolytic activity.
T0355 Valpramide Valpromide is a carboxamide derivative of valproic acid, used in the treatment of epilepsy and some affective disorders.
T0356 Nitromide Nitromide is an anti-parasitic drug.
T0359 2-Aminoheptane 2-Aminoheptane is used for proteomics research.
T0363 Morantel tartrate Morantel tartrate is an antinematodal agent used mainly for livestock.
T0367 Fluocinolone acetonide Fluocinolone acetonide is a glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has
T0368 Cinepazide maleate Cinepazide maleate, a maleate salt form of cinepazide, is a vasodilator.
T0376 Crotamiton Crotamiton is an antipruritic and a scabicidal agent available as a lotion or cream for topical use only. It is a colorless to slightly yellowish oil with a faint amine-like odor.
T0377 Clofazimine Clofazimine is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against va
T0379 Risedronic Acid Risedronic acid (Risedronate ), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
T0382 Eprodisate disodium Eprodisate Disodium is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
T0390 Alkomide Aklomide is used in poultry to treat parasites.
T0392 Artemisinin Artemisinin is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chlor
T0395 Pyrantel tartrate Pyrantel tartrate is broad spectrum anthelmintic for livestock.
T0396 Pipemidic acid Pipemidic acid, a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.
T0398 Carzenide Carzenide is an organic synthesis intermediate.
T0399 Methyl salicylate Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular
T0400 Nitroxoline Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.
T0402 Octocrilene Octocrylene is used as an ingredient in sunscreens and cosmetics. This organic compound can penetrate into the skin where it acts as a photosensitizer. This results in an increased
T0404 Hydroxyquinoline Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where i
T0408 Dehydrocholic acid Dehydrocholic acid is a synthetic bile acid, produced by the oxidation of cholic acid.
T0409 Phthalylsulfacetamide Phthalylsulfacetamide is a sulfonamide antibiotic used for topical application to the skin and the conjunctiva.
T0411 Calcium gluconate Calcium gluconate is the calcium salt of gluconic acid, used as a calcium replenisher in hypocalcemic states.
T0413 Cinromide Cinromide is used as a novel anticonvulsant agent.
T0415 Guanidine hydrochloride Guanidine hydrochloride is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is
T0416 Sodium gluconate Sodium Gluconate is the sodium salt of gluconic acid with a chelating property.
T0420 Pentetic Acid Pentetic Acid is an edetate and a chelating agent used in preparing radiopharmaceuticals.
T0422 Talc Talc is a mineral composed of hydrated magnesium silicate.
T0423 Edetate Trisodium Edetate Trisodiumis used to bind metal ions in the chelation therapy.
T0429 Glucosamine Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine may help to rebuild cartilage and
T0430 Imidazolidinyl urea Imidazolidinyl urea is an antimicrobial preservative used in cosmetics.
T0432 Diclofenac diethylamine Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
T0434 Dicurone Glucuronolactone is a naturally occurring chemical that is an important structural component of nearly all connective tissues. Glucuronolactone is also found in many plant gums.
T0435 Sulfinpyrazone Sulfinpyrazone is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
T0438 Proflavine Hemisulfate Proflavine Hemisulfate is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging
T0442 Bucetin Bucetin is a pharmaceutical drug that acts as an analgesic and antipyretic. Bucetin was withdrawn from use in 1986 due to renal toxicity.
T0447 Carvedilol Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti
T0452 Dropropizine Dropropizine, a racemic non-opiate antitussive agent, is served as a cough suppressant.
T0454 Florfenicol Florfenicol is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannhe
T0454L Florfenicol Florfenicol, a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) ha
T0461 Berberine hydrochloride Berberine hydrochloride is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used ora
T0464 Carbetapentane citrate Pentoxyverine Citrate, an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.
T0471 Decoquinate Decoquinate is a coccidiostat for poultry.
T0491 Ethyl vanillin Ethylvanillin is a flavorant used in the production of chocolate. It is about three times as potent as vanillin.
T0492 Dimethyl fumarate Dimethyl fumarate, a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T0495 Aminothiazole Aminothiazole, a thyroid inhibitor,displays antibacterial activity.
T0496 Creatinine Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
T0497 Lauroseptol Cetrimonium Bromide is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.
T0499 Oxybenzone Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
T0500 Capitrol Capitrol is a synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes
T0501 Leucobasal Leucobasal is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its ef
T0503 Meglumine Meglumine, a derivative of sorbitol, is used in conjunction with iodinated organic compounds as contrast medium.
T0507 L-Pyroglutamic acid L-Pyroglutamic acid, a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism.
T0509 Dermofongin Cloxyquin is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.
T0513 Iodoquinol Diiodohydroxyquinoline, a topical therapeutic agent, has satisfactory antibacterial properties.
T0517 Pancreatin Pancreatin is a mixture of several digestive enzymes secreted by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease.
T0519 Euquinine Euquinine generally is served as the febrifuge, antimalarial, and tonic.
T0526 2-Amino-5-nitrobenzophenone 2-Amino-5-nitrobenzophenone is used as industrial and organic intermediate.
T0527 2,3,4-Trimethoxybenzaldehyde 2,3,4-Trimethoxybenzaldehyde is used as medicine intermediate.
T0528 4-Fluoroanisole 4-Fluoroanisole is a intermediates in medicine, pesticide, liquid crystal materials.
T0529 Dulcitol Dulcitol is a sugar alcohol that is a metabolic breakdown product of galactose.
T0530 Flavanone Flavanones from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flava
T0531 Intermediate of Pregabalin Intermediate of Pregabalin.
T0533 N-Aminopiperidine hydrochloride 1-Aminopiperidine is a metabolite (M1) of the canabinoid receptor 1 antagonist Rimonabant, an antiobesity agent.
T0534 Bis(4-cyanophenyl)methanol Bis(4-cyanophenyl)methanol is a metabolite of Letrozole.
T0535 Memantine Related Compound B Memantine impurity B is an impurity of Memantine.
T0536 Cyclopropanecarbonitrile Cyclopropyl cyanide is the minimum carbon ring molecule with a cyanide group attached. It has mainly used in experiments with microwave spectroscopy, photodissociation, and rotatio
T0537 Desbenzyl Donepezil Hydrochloride Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil.
T0538 3-Methyloxindole 3-Methyl-2-oxindole is a reactant for O-acetylation reactions, enantioselective α-amination reactions and for aldol reactions with glyoxal derivatives and more.
T0539 Hydrocaffeic acid Dihydrocaffeic Acid is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective ac
T0540 Dibenzosuberol Dibenzosuberol, an organic compound, is used as a Pharmaceutical intermediate.
T0541 Fluoronaphthalene Fluoronaphthalene is incompatible with strong oxidizing agents.
T0542 Homoisovanillic acid Homoisovanillic acid is used as pharmaceutical intermediates.
T0544 Dichlorodiphenylmethane Dichlorodiphenylmethane is used as pharmaceutical intermediates.
T0545 1-(2-Hydroxyethyl)imidazolidine-2-thione 1-(2-Hydroxyethyl)imidazolidine-2-thione is used as pharmaceutical intermediates.
T0546 Trimethylacetic anhydride Trimethylacetic anhydride is used as medical intermediate
T0547 FlutaMide Related CoMpound B FlutaMide Related CoMpound B is used as pharmaceutical intermediates.
T0548 Methyl 5-methylnicotinate Methyl 5-methylnicotinate is used as pharmaceutical intermediates.
T0549 4'-tert-Butylacetophenone 4'-tert-Butylacetophenone is used as medical intermediate
T0550 Domperidone EP Impurity A Domperidone EP Impurity A is used as pharmaceutical intermediates.
T0551 D-Ornithine monohydrochloride D-Ornithine monohydrochloride is used as pharmaceutical intermediates.
T0552 Isonicotinamide Isonicotinamide is used as pharmaceutical intermediate to synthesis Cefalonium, etc.
T0553 4-Hydroxyisophthalic acid 4-Hydroxyisophthalic acid is used as medical intermediate
T0554 Dibutylurea Dibutylurea is used as pharmaceutical intermediates.
T0555 4-Diethylamino-2-butyn-1-ol 4-Diethylamino-2-butyn-1-ol is used as pharmaceutical intermediates.
T0556 6-Methoxy-2-naphthoic acid 6-Methoxy-2-naphthoic acid is an modulator of NMDAR.
T0557 3-(Methylamino)toluene 3-(Methylamino)toluene is used as dye intermediates
T0558 Hydroferulic acid Hydroferulic acid is used as the intermediates of perfume and essence.
T0559 Dibenzosuberone Dibenzosuberone, pharmaceutical intermediates, is used for the synthesis of drug amitriptyline.
T0560 3,3-Diphenylpropylamine 3,3-Diphenylpropylamine is used for synthetic drugs Mepramidil
T0561 2-Methoxy-5-sulfamoylbenzoic acid 2-Methoxy-5-sulfamoylbenzoic Acid is a metabolite of the antipsychotic drug, Sulpiride.
T0562 Protocatechuic acid Protocatechuic acid (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protec
T0563 Homoveratronitrile Homoveratronitrile is an impurity of Verapamil. It is also an intermediate in the preparation of the muscle relaxant Papverine.
T0564 1-Indanone 1-Indanone is the intermediate od Indinavir.
T0565 Bis(2-chloroethyl)amine hydrochloride Bis(2-chloroethyl)amine hydrochloride is used as pharmaceutical intermediate.
T0566 2-Methylbenzhydrol 2-Methylbenzhydrol is used as pharmaceutical intermediates.
T0567 2-Amino-5-chlorobenzoic acid 5-Chloroanthranilic Acid is a metabolite of the pesticide Chlordimeform. It can be used in the preparation of disease-modifying antirheumatic drugs (DMARDs).
T0568 Homoveratrumic acid Homoveratrumic acid is the papaverine intermediate, used to synthesis cardiovascular drugs.
T0569 Pyrazinoic acid Pyrazinoic acid is the intermediate of pyrazole thiamethoxam sulfur.
T0570 3,5-Dihydroxybenzoic acid 3,5-Dihydroxybenzoic Acid is a metabolite of alkylresorcinol in human urine and plasma. It is also used as a biomarker of whole grain wheat and rye.
T0571 2-Methylbenzene-1-sulfonamide 2-Methylbenzene-1-sulfonamide is used for saccharin, pharmaceutical intermediates, etc.
T0572 Methyl EudesMate Methyl EudesMate is the intermediate of antibacterial efficiency medicine trimethoprim.
T0573 2-Methoxynaphthalene 2-Methoxynaphthalene is served as Odor agents.
T0574 Diphenyl sulfide Diphenyl sulfide is used as pesticide, medicine, dye intermediates.
T0575 1-Methylimidazole 1-Methylimidazole is a metabolite of 1-methyl-2-thioimidazole (methimazole) which inhibits bone resorption.
T0576 Diethylaminoethoxyethanol Diethylaminoethoxyethanol is served in the production of cough medicine Toclase and so on.
T0577 Chlorobenzothiazolinone Chlorobenzothiazolinone inhibits recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay with activity va
T0578 Erythrosin B Iodeosin, a tetraiodofluorescein, is used as a red coloring in some foods (cherries, fish), as a stain of some cell types, and as a disclosure of DENTAL PLAQUE. Its molecular struc
T0580 4-Pentynoic acid 4-Pentynoic acid has been used in reactions with 1-bromo-1-alkynes in the presence of a Pd catalyst yields biologically active ynenol lactones. It also is used in a synthesis of a
T0581 Isomaltose Isomaltose is a reducing disaccharide, similar to maltose, but with an α-(1-6)-linkage instead of the α-(1-4)-linkage.
T0582 Fructooligosaccharides Fructooligosaccharides is a levorotatory monosaccharide and an isomer of glucose.
T0583 Erythritol Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
T0584 Maltose Maltose is a dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing.
T0584L D-(+)-Maltose monohydrate D-(+)-Maltose monohydrate, a dextrodisaccharide from starch and malt, is used as a fermentable intermediate and sweetening agent in brewing.
T0585 Maltitol Maltitol is a sugar alcohol (polyol) used as a sugar substitute.
T0586 Lactose Lactose is a disaccharide derived from galactose and glucose that is found in milk.
T0587 L(+)-Arabinose Arabinose is an aldopentose, including an aldehyde (CHO) functional group.
T0589 Xylitol Xylitol is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.
T0591 Alpha-D-galactose D-Galactose is an aldohexose that exists naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metaboli
T0592 Mannose Mannose is a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants.
T0596 Phenylhydantoin 5-Phenylhydantoin is a metabolite of Mephenytoin. 5-Phenylhydantoin has been shown to bind to voltage-dependent sodium channels (NVSC) and has anti-epileptic properties.
T0598 Iminostilbene Iminostilbene (Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.
T0599 N-Methyl-N-(trimethylsilyl)trifluoroacetamide N-Methyl-N-(trimethylsilyl)trifluoroacetamide is a metabolite of Famprofazone in humans.
T0600 10,11-Dihydrocarbamazepine 10,11-Dihydrocarbamazepine is used as pharmaceutical intermediates.
T0601 Phthalic Acid Monobenzyl Ester Monobenzyl Phthalate is Phthalate metabolite.
T0604 Desalkylterbuthylazine Desalkylterbuthylazine is used as pharmaceutical intermediates.
T0606 Monobutyl Phthalate Monobutyl Phthalate is a di-n-Butylphthalate (DBP) metabolite.
T0607 Dihydroartemisinin Dihydroartemisinin is a metabolite of artemisinin.
T0608 Heptachlor-endo-epoxide Heptachlor-endo-epoxide is a degradation product of heptachlor that occurs in soil and in or on crops when treatments with heptachlor, an insecticide, have been made. Forms readily
T0609 Azobenzene Azobenzene is a compound constituted of two phenyl rings linked by an N=N double bond. Azobenzene is the simplest example of an aryl azo chemical compound. The term 'azobenzene' or
T0611 4-Hydroxy-3-methoxymandelic acid 4-Hydroxy-3-methoxymandelic acid is a chemical intermediate.
T0612 DL-6-Methoxy-Alpha-Methyl-2-Naphthalenemethanol DL-6-Methoxy-Alpha-Methyl-2-Naphthalenemethanol is used as pharmaceutical intermediates.
T0613 Beta-Hydroxyisovaleric acid Used as medical intermediates
T0614 4-Amino-5-Chloro-2-Methoxybenzoic Acid 4-Amino-5-chloro-2-methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite.
T0615 1-(3-Chlorophenyl)piperazine hydrochloride 1-(3-Chlorophenyl)piperazine hydrochloride is used for the synthesis of trazodone, Etoperidone, Nefazodone, etc.
T0621 Diphenyl oxide Diphenyl oxide is used in the manufacture of spices and dyes.
T0622 2-Chlorophenothiazine 2-Chlorophenothiazine is used as the intermediate of Chlorpromazine hydrochloride.
T0623 Diphenylacetonitrile Diphenylacetonitrile is used as herbicide and industrial intermediate.
T0624 4-Hydroxybenzophenone 4-Hydroxybenzophenone is used as an intermediate of infertility drugs Clomifene.
T0628 Iminodibenzyl Iminodibenzyl is used for the intermediates of antiepileptic drug carbamazepine.
T0629 Atropic acid Atropic acid (Ipratropium EP Impurity D) is an impurity of Ipratropium bromide and Atropine Sulfate.
T0630 Ethyleneurea Ethyleneurea is used as a formaldehyde scavenger and intermediate.
T0631 2-Phenylbutyric acid 2-Phenylbutyric Acid is used as an industrial intermediate.
T0632 Gallic acid trimethyl ether Gallic acid trimethyl ether are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in
T0633 (2-Chlorophenyl)phenyl-methanone (2-Chlorophenyl)phenyl-methanone is used as pharmaceutical intermediate.
T0634 2-Acetyl-4-butyramidophenol 2-Acetyl-4-butyramidophenol is gray crystalline powder.
T0635 p-(2-Methoxyethyl) phenol p-(2-Methoxyethyl) phenol, an important kind of pharmaceutical intermediates, is primarily used in the synthesis of metoprolol which is effective drugs in the therapy of cardiovasc
T0636 4-Methylmorpholine N-oxide 4-Methylmorpholine N-oxideis an organic compound, used in organic chemistry as a co-oxidant and sacrificial catalyst in oxidation reactions.
T0637 2-Acetyl-6-methoxynaphthalene 2-Acetyl-6-methoxynaphthalene, the key intermediate of naphthalene tome and naproxen, is used in synthetic non-steroidal anti-inflammatory analgesic medicine and.
T0638 2-Methyl-4-nitroimidazole 2-Methyl-5-nitroimidazole is a kind of small molecular compounds.
T0640 Butyl benzyl phthalate Butyl benzyl phthalate is used as a plasticizer for PVC.
T0643 Diclofenac Amide Diclofenac Amide is used as a intermediates of Diclofenac.
T0644 3-Amino-5-methylisoxazole 3-Amino-5-methylisoxazole is pharmaceutical intermediates, used in the production of sulfonamide drugs.
T0645 N-(1-Adamantyl)acetamide N-(1-Adamantyl)acetamide is used as intermediates for synthesis of amantadine hydrochloride.
T0650 Phenyl acetate Phenyl acetate, the ester of a phenol and acetic acid, can be produced by reacting acetic anhydride with phenol. Another way is produced by decarboxylation of aspirin.
T0653 Tris(2-chloroethyl) phosphate Tris(2-chloroethyl) phosphate is served as flame retardants.
T0657 3,4-Dimethoxybenzyl alcohol 3,4-Dimethoxybenzyl Alcohol is an organic compound.
T0658 2-(2-Hydroxyethyl)pyridine 2-Pyridineethanol is used as an industrial chemistry intermediate.
T0659 Bispyrazolone Bispyrazolone is light yellow or white crystalline powder.
T0661 Dimethylsulfamoyl chloride Dimethylsulfamoyl Chloride is a kind of small molecular compound.
T0662 2-Hydroxybenzimidazole 2-Hydroxybenzimidazole is used as an intermediate in industry.
T0664 Nicotinic acid hydrazide Nicotinic acid hydrazide is a small molecular compound.
T0665 2,6-Dihydroxypurine Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most
T0666 4-Chlorosalicylic acid 4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
T0667 Flecainide Impurity D Flecainide Impurity D is used as an intermediate in industry.
T0668 1-Aminohydantoin hydrochloride 1-Aminohydantoin hydrochloride is an organic compound.
T0669 Chloramine-T Chloramine-T is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.
T0671 2-Naphthol 2-Naphthol is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring.
T0686 Orlistat Orlistat is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.
T0690 Quinine Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy
T0691 Sulisobenzone Sulisobenzone (benzophenone-4), an ingredient in certain sunblocks, protects the skin against damage by short-wave UVA ultraviolet light and UVB.
T0693 Niflumic acid Niflumic acid is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.
T0694 Pranlukast Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or in
T0695 Avobenzone Avobenzone, an oil-soluble ingredient, is a dibenzoylmethane derivative used in sunscreen products to absorb the full spectrum of UVA rays.
T0697 Aspartame Aspartame, an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester.
T0698 Dioxybenzone Dioxybenzone (benzophenone-8) is a derivative of benzophenone, used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.
T0699 Sulfamonomethoxine Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
T0701 Broxyquinoline Broxyquinoline is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes.
T0710 L-Cycloserine L-cycloserine irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of ga
T0715 Chlormezanone Chlormezanone is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
T0719 Tetrabenazine Tetrabenazine is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles
T0721 Piroctone olamine Piroctone olamine is a compound sometimes used in the treatment of fungal infections. Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone.
T0722 Ursolic acid Ursolic acid(Bungeolic acid), a natural pentacyclic triterpenoid carboxylic acid, shows anti-tumor effects.
T0724 Formononetin Formononetin is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
T0727 Piperonyl butoxide Piperonyl butoxide is an insecticide synergist, particularly for rotenone and pyrethroids.
T0729 Benzyl benzoate Benzyl benzoate is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe it
T0730 Triacetin Triacetin is a triglyceride that is used as an antifungal agent.
T0738 Urea Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for about one-half of the
T0739 Guaifenesin Guaifenesin is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.
T0741 Sulfamethazine Sulfamethazine is a sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
T0743 DL-Carnitine DL-Carnitine is the constituent of liver and striated muscle. In therapeutically It is used to stimulate pancreatic and gastric secretions and to treat hyperlipoproteinemias.
T0744 Zinc undecylenate 10-Undecenoic acid zinc salt, a synthetic or natural fungistatic fatty acid, is used topically in creams against eczemas, fungal infections, ringworm, and other cutaneous condition
T0755 Carbaglu Carglumic acid is an orphan drug used to treat hyperammonemia in patients with N-acetyl glutamate synthase absence. This rare hereditary disease results in elevated blood levels of
T0756 Ethoxyquin Ethoxyquin is an antioxidant used in animal feeds.
T0762 Trans-Anethole Anethole (anise camphor), an organic compound, is widely served as a condiment substance. It is a derivative of phenylpropene, a type of aromatic compound that exists widely in ess
T0763 Diolane Diolane, colorless liquid, is a chiral diol. It is an industrial compound produced from diacetone alcohol by hydrogenation.
T0768 Oxolamine citrate Oxolamine is a cough suppressant that is able to be used as a generic drug in many jurisdictions.
T0770 Carbadox Carbadox is an antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibit
T0771 Casanthranol Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions
T0772 Troxerutin Troxerutin, a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.
T0777 Tilmicosin Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia hae
T0781 Dithiopropanol An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is
T0787 Butylated hydroxyanisole Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.
T0791 Reserpine Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion o
T0799 Lactulose Lactulose ,a synthetic disaccharide ,is used in the treatment of constipation and hepatic encephalopathy.
T0801 Tannic acid Tannic acid is a novel hERG channel blocker.
T0803 Acetrizoic acid Acetrizoic acid is the first monomeric ionic compound used as an X-ray contrast agent.
T0807 Basibrol 2,2,2-Tribromoethanol is an organic compound used to anesthetize mice.
T0819 Spiramycin Spiramycin is a macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is u
T0823 Thioctamide Lipoamide is a trivial name for 6,8-dithiooctanoic amide. It is 6,8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an
T0827 Cefsulodine sodium Cefsulodin sodium salt hydrate is a β lactam antibiotic.
T0828 Bromhexine hydrochloride Bromhexine hydrochloride is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. 
T0829 Etofylline Etofylline is used for difficulty in breathing, asthma, breathing difficulty and other conditions.
T0833 Benzoic acid Benzoic acid is a fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
T0834 Ethylparaben Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
T0844 Sulfamethoxypyridazine Sulfamethoxypyridazine is a sulfanilamide antibacterial agent.
T0845 Cyromazine Cyromazine is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.
T0850 Primaquine diphosphate Primaquine Phosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclea
T0852 Carbazochrome sodium sulfonate Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for the treatment of hemorrhoids.
T0860 Mefloquine hydrochloride Mefloquine is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T0861 Tylosin tartrate Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry.
T0872L Amprolium Hydrochloride Amprolium is a coccidiostat that interferes with thiamine metabolism.
T0873 Dinitolmide Dinitolmide, a poultry feed additive, is a coccidiostat for poultry.
T0874 Dimetridazole Dimetridazole is a drug that combats protozoan infections. It is a nitroimidazole class drug. It has been banned by the Canadian government as a livestock feed additive.
T0875 Acetylcysteine Acetylcysteine is the N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effect
T0876 Clioquinol Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
T0877 Gallic acid Ursolic acid (UA), a pentacyclic triterpene acid, is used in anticancer chemotherapies.
T0881 6-Aminocaproic acid Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
T0885 Sulfamethoxazole Sulfamethoxazole is a Sulfonamide Antimicrobial. The mechanism of action of sulfamethoxazole is as a Cytochrome P450 2C9 Inhibitor. The chemical classification of sulfamethoxazole
T0887 D(+)-Glucose D(+)-Glucose is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeuti
T0889 Saccharin Flavoring agent and non-nutritive sweetener.
T0891 Sulphadione Sulfapyridine is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.
T0896 Furaltadone hydrochloride Furaltadone hydrochloride is an antibacterial and shows distinct curative effect in the treatment of coccidiosis.
T0898 Chloroxylenol Chloroxylenol (4-chloro-3,5-dimethylphenol), a broad spectrum antimicrobial chemical compound, is used to control virus, bacteria, fungi, and algae. It is used in households and ho
T0899 Dehydroacetic acid Dehydroacetic acid, a pyrone derivative, is served frequently as a fungicide and bactericide.
T0900 Cetylpyridinium chloride monohydrate Cetylpyridinium chloride (CPC), a cationic quaternary ammonium compound, is used in certain classes of throat sprays, mouthwashes, lozenges, toothpaste, nasal sprays, and breath sp
T0901 Chlorobutanol Chlorobutanol is a chemical preservative, sedative hypnotic and weak local anaesthetic similar in nature to chloral hydrate. It has antibacterial and antifungal properties. Chlorob
T0908 Chloquinan Chlorquinaldol is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity.
T0910 Terpin Monohydrate Terpin hydrate, a cis-form hydrate, is derived from sources such as oil of turpentine, oregano, thyme, and eucalyptus. It is used as an insect repellent and expectorant. Terpin hyd
T0912L Tetracycline Tetracycline is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
T0914 Metacetamol METACETAMOL is an organic compound.
T0917 Sulfaquinoxaline sodium Sulfa drugs, used in the treatment of avian coccidiosis.
T0919 Benfluorex hydrochloride Tamoxifen is an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM).
T0921 Sulfabenzamide Sulfabenzamide is a sulfonamide antibacterial agent used alone or with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation.
T0922 Zoxazolamine Zoxazolamine is a uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.
T0924 Benzocaine Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
T0925 Allantoin Allantoin, a urea hydantoin found in urine and plants, is used in dermatological preparations.
T0926 Azelaic acid Azelaic acid is bactericidal against Propionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of microbial cellular proteins. Azelaic Ac
T0927 Butylparaben Butylparaben is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.
T0933 Delta-Gluconolactone Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure
T0940 Acesulfame Potassium Acesulfame potassium is a non-nutritive sweetener.
T0941 Cyclamic acid Cyclamic acid is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogeni
T0949 Amstat Tranexamic acid is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.
T0953 Cefazolin sodium salt Cefazolin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin Sodium is the sodium salt of cefazolin, a b
T0955 Oxyclozanide Oxyclozanide is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.
T0956 Abamectin Avermectin B1 (Abamectin) is served as anthelmintic and insecticide.
T0959 Ethopabate Ethopabate is an inhibitor of folate metabolism, used as a coccidiostat in poultry.
T0960 Iopanoic acid Iopanoic acid is an iodine-containing radiocontrast medium used in cholecystography.
T0961 Trometamol Trometamol is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inf
T0967 Teicoplanin Teicoplanin is a semisynthetic glycopeptide antibiotic, used to treat Gram-positive bacteria.
T0969 Doramectin Doramectin is an antiparasitic agent.
T0977 Medrysone Medrysone is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellu
T0983 Artamine Artamine, possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artam
T0983L DL-Penicillamine DL-Penicillamine is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used o
T0985 Oxacillin sodium Oxacillin sodium is an antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.
T0989 7-Aminocephalosporanic acid 7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
T1001 Dicloxacillin sodium Dicloxacillin NaOH is a narrow-spectrum β-Lactam antibiotic of the penicillin class, used to treat infections caused by susceptible Gram-positive bacteria.
T1003 Tylosin Tylosin is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
T1004 Benzyladenine 6-Benzylaminopurine, benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit ric
T1005 Amoxicillin Amoxicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Amoxicillin Anhydrous is the anhydrous form of a b
T1007 Lupetidin Lupetidin is a neuropathic blocker, with antihypertensive effect.
T1017 Fluoroethyl Flurothyl is a convulsant used in experimental animals.
T1023 Cefoxitin sodium Cefoxitin sodium is a semisynthetic cephamycin antibiotic resistant to beta-lactamase.
T1028 Moxonidine Moxonidine is a selective agonist at the imidazoline receptor subtype 1, acting as an antihypertensive drug.
T1031 Cloxacillin sodium monohydrate Cloxacillin Sodium is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
T1033 Monensin sodium salt Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.
T1034 Docetaxel Docetaxel is a microtubule inhibitor that inhibits microtubule disassembly (IC50: 0.2 μM).
T1035 Hesperidin Hesperidin is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
T1036 Netilmicin sulfate Netilmicin Sulfate is an aminoglycoside antibiotic.
T1037 Doripenem Hydrate Doripenem Hydrate is a broad-spectrum injectable antibiotic, used for Gram-positive, Gram-negative and anaerobic pathogens.
T1041 Risedronate Sodium Risedronate sodium is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatment of OSTEOPOROSIS.
T1043 Salifungin Detail unknown.
T1044 Clopidol Clopidol is a very effective anticoccidial agent used in poultry.
T1053 Mebeverine hydrochloride Mebeverine hydrochloride, a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.
T1059 Retinol palmitate Vitamin A Palmitate is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.
T1061 Toltrazuril Toltrazuril, an antiprotozoal agent, has effect on Coccidia parasites.
T1063 Ticarcillin disodium Ticarcillin Disodium is the disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Simil
T1067 Amphotericin B Amphotericin B is an antifungal agent with a broad spectrum of activity against many fungal species.
T1068 Anthralin Anthralin is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS
T1070 Cefmetazole sodium Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of eff
T1075 Vitamin K1 Vitamin K1 a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.
T1078 Sulfadimethoxine Sulfadimethoxine is a sulfanilamide that is used as an anti-infective agent.
T1080 2-Aminoethanethiol Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T1082 Benzyl isothiocyanate Benzyl isothiocyanate (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atheroscler
T1091 Chlortalidone Chlorthalidone is a benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
T1098 Denatonium benzoate Denatonium, a quaternary ammonium cation, is a compound of a salt with an inert anion like saccharide or benzoate. Its structure is involved in the local anesthetic lidocaine which
T1100 Polymyxin B sulfate Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic deterge
T1101 Minocycline hydrochloride Minocycline is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline ca
T1107 Sarafloxacin hydrochloride Sarafloxacin hydrochloride, a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.
T1108 Nithiamide Nithiamide is an orally available antiprotozoan agent used in the treatment of vaginal trichomoniasis.
T1109 Zucapsaicin Zucapsaicin is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeut
T1113 Imazalil Enilconazole is an Agricultural fungicide Enilconazole is a fungicide widely used in agriculture, particularly in the growing of citrus fruits. It is also called Imazalil, Chlorami
T1114 Ciclopirox ethanolamine Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
T1126 Penicillin V potassium salt Penicillin V potassium is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.
T1129 Benfotiamine Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.
T1134 Clofoctol Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria,used in the treatment of upper and lower respiratory tract infections.
T1136 Diastase Diastase is any one of a group of enzymes which catalyses the breakdown of starch into maltose.
T1137 Clorsulon Clorsulon is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
T1138 Taurocholic acid sodium salt hydrate Taurocholic acid sodium salt hydrate is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredient of the bile of carnivorous animals, is used as
T1141 Fenbendazole Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.
T1145 Diminazene Aceturate Diminazene is a trypanocidal agent.
T1148 Menbutone Menbutone is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly
T1159 Leflunomide Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
T1160 Fusidine Fusidine is an antibiotic isolated from the fermentation broth of Fusidium coccineum.
T1161 Protionamide Protionamide is a thioamide derivative with antitubercular activity.
T1162 Acipimox Acipimox is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insuli
T1169 Moguisteine Moguisteine is a new-type peripheral non-narcotic antitussive drug.
T1172 Diclazuril Diclazuril is a coccidiostat.
T1187 Bifonazole Bifonazole acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called erg
T1192 Protoporphyrin IX Protoporphyrin IX is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll.
T1208 Citicoline sodium Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citic
T1214 Ribostamycin sulfate Ribostamycin, an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
T1219 Sisomicin Sulfate Sisomicin Sulfate is the sulfate salt form of sisomicin, a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is structurally similar to gen
T1220 Ethidium bromide A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including
T1223 Ceftriaxone sodium Ceftriaxone sodium salt is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
T1224 Cefuroxime sodium Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal
T1226 Bacitracin Bacitracin, a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.
T1227 Cepazine Cepazine is a second generation oral cephalosporin antibiotic.
T1230 Pamabrom Pamabrom is a diuretic, used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with the premenstrual and menstrual periods.
T1249 Beclamide Beclamide (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was st
T1251 DCU Dicloralurea is a veterinary food additive that inhibits methane production in herbicide ruminants.
T1252 PAMBA 4-(Aminomethyl)benzoic acid, an antifibrinolytic, is an unnatural amino acid derivative.
T1253 Chlorindanol Chlorindanol is a new antiseptic agent.
T1254 Chlorophyllin Chlorophyllin sodium copper salt is a semi-synthetic mixture of water-soluble sodium copper salts derived from chlorophyll, primarily used as a food additive and alternative medici
T1257 Ubenimex Ubenimex competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory a
T1259 Pyrantel pamoate Pyrantel pamoate is a depolarizing neuromuscular blocking agent.
T1260 Sodium cromoglycate Cromolyn sodium is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
T1263 Levonorgestrel Levonorgestrel is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum Fertilization.
T1268 Dixanthogen Dixanthogen is an ectoparasiticide.
T1285 Anethole trithione Anethole trithione is a bile secretion-stimulating drug that restores salivation and relieves the discomfort of dry mouth in chemotherapy-induced xerostomia.
T1286 Vincamine Vincamine is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorder
T1289 Sodium fusidate Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infecti
T1290 Oxiconazole nitrate Oxiconazole Nitrate is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fu
T1297 Eugenol Eugenol is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity.
T1299 Roniacol Roniacol is an alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and th
T1301 Guaiacol Guaiacol is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can b
T1303 Auranofin Auranofin is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness.
T1311 4-aminobenzoic acid 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.
T1317 Cinchonidine Cinchonidine is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
T1319 Diatrizoate sodium Diatrizoate Sodium is an iodinated radiopaque X-ray contrast medium. Diatrizoate sodium blocks X-rays, thereby allowing body structures containing iodine to be delineated in contra
T1323 Artemether Artemether is an antimalarial agent used to treat acute uncomplicated malaria.
T1337 Pamidronate disodium salt Pamidronate disodium, a nitrogen-containing bisphosphonate, can help to strengthen bones.
T1338 Sucralfate Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
T1340 N-Carbethoxy-4-piperidone N-Carbethoxy-4-piperidone is an aminopyrimidine derivative, compositions containing them and there served as pharmaceuticals.
T1342 3-Chloropropiophenone 3-Chloropropiophenone is a small molecular compound.
T1343 Leucocrystal Violet Leucocrystal violet is a triphenylmethane dye.
T1344 4-Chloro-4'-hydroxybenzophenone 4-Chloro-4’-hydroxybenzophenone is an organic compound.
T1345 1,1-Bis(Methylthio)-2-Nitroethylene 1,1-Bis(Methylthio)-2-Nitroethylene is an organic compound.
T1346 1-Phenyl-1,2-ethanediol 1-Phenyl-1,2-ethanediol is O-benzyl oxime ether derivatives and used as pesticides.
T1347 2-Benzothiazolamine 2-Aminobenzothiazole is an organic compound.
T1348 Diphenyl phosphate Paint additives and coating additives not described by other categories
T1349 5-Fluorouridine 5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucle
T1350 4-Butoxyphenol 4-Butoxyphenol is an organic compound.
T1352 Adenosine 5'-triphosphate disodium salt Adenosine 5'-triphosphate disodium salt is a P2 purinoceptor agonist.
T1353 DL-Mevalonolactone Mevalonic acid is very soluble in water and polar organic solvents. It exists in equilibrium with its lactone form, called mevalonolactone, that is formed by internal condensation
T1355 Methyl 3,5-dihydroxybenzoate Methyl 3,5-dihydroxybenzoate was used in the synthesis of cored dendrimers.
T1356 4-Hydroxy-3-methoxybenzylamine hydrochloride Vanillylamine is an alkaloid that is an intermediate in the biosynthesis of capsaicin. Vanillylamine is produced from vanillin by the enzyme vanillin aminotransferase.
T1357 TriMetazidine EP IMpurity-D It is an organic compounds with molecular fomula C10H14O4.
T1358 2,3-Dichloroanisole 2,3-Dichloroanisole is a intermediate product.
T1359 2,3-Dihydrobenzofuranyl-5-acetic acid 2,3-Dihydro-5-benzofuranacetic Acid is used as Pharmaceutical material and intermeidates.
T1360 4-Nitro-3-trifluoromethyl aniline it is also called 5-Amino-2-nitrobenzotrifluoride.
T1361 2-Trifluoromethyl thioxanthone 2-Trifluoromethyl thioxanthone is a pale yellow crystal with molecular fomula C14H7F3OS.
T1362 6-Hydroxypurine Hypoxanthine, a purine derivative, is a potential free radical generator. It has been used in studies as in indicator, along with uric acid and allantoin, of in vivo free radical r
T1364 Cefalexine EP IMpurity B Cefalexine EP IMpurity B is used as an antibiotic.
T1367 Demeton-s-methyl sulfone Demeton-S-methyl Sulfone is a kind of pesticides.
T1369 1-Methylindazole-3-carboxylic acid 1-Methylindazole-3-carboxylic acid is an excellent solvent with a proper boiling point.
T1370 2-Amino-5-Fluorophenol 2-Amino-5-Fluorophenol is an organic compunds.
T1371 1H-1,2,4-Triazole-3-carboxylic acid It has been granted the patent to have property to Inhibit protein isoprenyl transferases.
T1372 2-Methoxybenzylamine 2-Methoxybenzylamine is an organic compounds
T1375 Methomyl Oxime Methomyl is the active ingredient in commercial fly bait granules which are mixed with a cola drink to kill bothersome raccoon, skunk and opossum.
T1380 Alodan Alodan is an organic chloride insecticide.
T1381 Milbemycin oxime Milbemycin oxime is a broad spectrum antiparasitic, used as a veterinary drug.
T1383 Biscomate Biscomate is used in the treatment of hookworms.
T1391 4-Methylumbelliferone Hymecromone is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the deter
T1392 Fluorescein Fluorescein is a phthalic indicator dye, use as a synthetic fluorescent tracer.
T1395 Diatrizoic Acid Diatrizoic Acid is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.
T1399 Sucralose Sucralose, an artificial sweetener, is not degraded by the body, so it is noncaloric.
T1403 Climbazole Climbazole is a broad-spectrum imidazole antifungal agent with anti-dandruff benefits.
T1414 Mesna Mesna is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
T1430 Betamipron Betamipron is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.
T1431 Khellin Khellin is a vasodilator that also has bronchodilatory action.
T1440 Ethacridine lactate monohydrate Ethacridine lactate hydrate is a topically applied anti-infective agent.
T1443 Memantine hydrochloride Memantine hydrochloride is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
T1447 Fenchlonine Fenclonine is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharm
T1457 Deferasirox Deferasirox is an oral iron chelating agent used to treat chronic iron overload.
T1466 Nadifloxacin Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
T1479 Isosorbide dinitrate Isosorbide dinitrate is a vasodilator used in the treatment of angina pectoris.
T1481 Fudosteine Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
T1491 Atovaquone Atovaquone is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
T1494 Alarelin Alarelin acetate is a synthetic GnRH agonist.
T1513 Telbivudine Telbivudine is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The
T1515 Bromindione Bromindione is a new anticoagulant.
T1516 Curcumin Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation
T1522 Iopromide Iopromide is a low osmolar, non-ionic contrast agent for intravascular use.
T1529 Miglitol Miglitol is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
T1532 Pidotimod Pidotimod is a synthetic dipeptide with immunomodulatory properties.
T1533 Valganciclovir hydrochloride Valganciclovir Hydrochloride is a hydrochloride salt form of valganciclovir, a prodrug form of ganciclovir, a nucleoside analog of 2'-deoxyguanosine, with antiviral activity. After
T1544 Olsalazine disodium Olsalazine sodium is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
T1546 Nitazoxanide Nitazoxanide is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreduct
T1549 Raloxifene hydrochloride Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects o
T1550 Thiamphenicol Thiamphenicol is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.
T1554 Iohexol Iohexol is an X-ray contrast medium containing iohexol in various concentrations, from 140 to 350 milligrams of iodine per milliliter.
T1556 Ornidazole Ornidazole is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
T1565 Deferidone Deferiprone is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
T1576 Iopamidol Iopamidol is an organic iodine compound and used as a non-ionic water-soluble radiographic contrast medium.
T1585 Metolazone Metolazone is a quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
T1588 Kemantane Idramantone is an immune agonist.
T1589 D-Cycloserine Cycloserine is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
T1593 Ezetimibe Ezetimibe is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.
T1598 Rimantadine hydrochloride Rimantadine hydrochloride is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
T1599L Ibandronate sodium Ibandronate Sodium is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
T1601 Lomustine Lomustine is an alkylating agent of value against both hematologic malignancies and solid tumors.
T1610 Metaxalone Metaxalone (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other muscu
T1630 Tiopronin Tiopronin, a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.
T1637 Deferoxamine Mesylate Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
T1638 N-Acetylneuraminic acid N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. S
T1639 Amlexanox Amlexanox is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils
T1647 Ronidazole Ronidazole is an antiprotozoal and antimicrobial agent used mainly in veterinary practice.
T1648 Vitamin E (+)-α-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
T1654 Pentamidine isethionate Pentamidine isethionate is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.
T1660 Silibinin Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibin
T1662 ALA hydrochloride Aminolevulinic acid hydrochloride is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
T1666 Fludrocortisone acetate Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-res
T1672 Dimesna Dimesna is a synthetic derivative of dithio-ethane sulfonate with uroprotective properties.
T1675 Adefovir dipivoxil Adefovir Dipivoxil is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes vi
T1678 Nystatin Nystatin is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis.
T1684 Nitisinone Nitisinone(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
T1685 2-Amino-5-chlorobenzophenone 2-Amino-5-chlorobenzophenone is used as pharmaceutical intermediates.
T1686 Hematoxylin Hematoxylin is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.
T1689 Enalapril IMpurity B Enalapril IMpurity B is Moexipril intermediate and is the main metabolite of Imidapril.
T1690 BroMhexine IMpurity B Quinolones used as MRS inhibitors and bactericides.
T1691 4-Formylbenzoic acid It is an organic compunds with molecular fomula C8H6O3.
T1697 debutylbupivacaine Debutylbupivacaine is the intermediate of ropivacaine hydrochloride and bupivacaine.
T1698 Carvedilol EP IMpurity E Carvedilol EP IMpurity E is used as a pharmaceutical intermediate.
T1701 H-ASP-PHE-OH Used as pharmaceutical intermediates
T1702 Nortropinone hydrochloride Nortropinone hydrochloride is used as a pharmaceutical intermediate.
T1705 4-Amino-5-imidazolecarboxamide An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation o
T1706 4-Hydroxy-3-nitrophenylacetic acid 4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.
T1709 2'-Deoxyinosine 2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.
T1716 Echinacoside Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitri
T1721 2'-Deoxyuridine 2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic ane
T1722 5-Amino-4-imidazolecarboxamide 5-Amino-4-imidazolecarboxamide is an imidazole derivative.
T1723 ADP Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.
T1727 4-Cyclohexyl-1-phenylthiosemicarbazide N/A
T1732 Semicarbazide hydrochloride Semicarbazide is Snow white crystals and used as a reagent for ketones and aldehydes with which it affords crystalline compounds having characteristic melting points.
T1733 Ciprofloxacin EP IMpurity A Fluoroquinolonic Acid is an antibiotic and antimicrobial agent.
T1771 Ro 48-8071 fumarate Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
T1802 ZLN005 ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.
T1816 Z-JIB-04 Z-JIB-04 is an isomer of JIB-04.
T1833 NSI-189 NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
T1844 KPT-330 KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells.
T1856 TPT-260 TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base form.
T1858 CID 797718 CID797718 is a protein kinase D1 (PKD1) inhibitor.
T1864 Fabomotizole Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.
T1866 AT-56 AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.
T1880 P7C3 The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally pr
T1965 Bikinin Bikinin, a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.
T1984 Cinaciguat Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in clinical development for acute decompensated heart failure.
T1990 (R)-P7C3-Ome P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and si
T1992 Mertansine Mertansine refers to the thiol-containing maytansinoid, DM1 (N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thio
T1997 JNJ-31020028 JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2
T2010 S0859 S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH.
T2020 RGW 611 Detail unknown.
T2021 Dihydroethidium Dihydroethidium is a superoxide indicator.
T2031 NSC-41589 NSC-41589 is N-[2-(methylsulfanyl) phenyl]acetamide.
T2034 AG-1557 AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
T2042 CTx0294885 CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase captur
T2046 Nimorazole Nimorazole is a nitroimidazole anti-infective.
T2075 Pyrazolo[1,5-a]pyrimidine 4h Detail unknown.
T2102 FH1 FH1 (BRD-K4477), a small molecule, enhances the functions of hepatocytes and promotes differentiation hepatocytes derived by iPS.
T2112 Fexinidazole Fexinidazole is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leis
T2130 Propidium Iodide Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also for
T2136 Geniposidic Acid Geniposidic acid, an iridoid glucoside, used in therapy of jaundice, inflammation and hepatic disorders.
T2149 Eburnalritardo Eburnalritardo is a vasodilator. Eburnalritardo is a vinca alkaloid and a metabolite of vincamine.
T2151 Methyl carbamate Methyl carbamate is a white crystal.
T2152 Dibutyl carbonate N/A
T2161 Cardiogenol C hydrochloride Cardiogenol C hydrochloride is a cardiomyogenesis inducer in embryonic stem cells.
T2163 Dihydrocapsaicin Dihydrocapsaicin is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsa
T2164 Wiskostatin Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization.
T2167 lutidinic acid 2,4-Pyridinedicarboxylic acid is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.
T2178 AMI-5 Eosin yellowish is a versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in s
T2181 Scopolamine N-oxide HBr Scopolamine N-oxide HBr is an antagonist of the muscarinic acetylcholine.
T2184 Sulfachloropyridazine Sulfachloropyridazine is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
T2184L Sulfamethazine sodium salt Sulfamethazine Sodium is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry.
T2186 Tris(2,2,2-trifluoroethyl) borate Tris(2,2,2-trifluoroethyl) borate is mostly used in condensation reactions. It has been shown to promote the direct formation of amides from carboxylic acids and amines as well a
T2197 10-Deacetylbaccatin III 10-Deacetylbaccatin-III is an intermediate for taxol analog preparations with anti-cancer activity.
T2199 Myclobutanil Myclobutanil is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor, specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical componen
T2201 6-Mercaptopurine monohydrate 6-Mercaptopurine anhydrous is a Nucleoside Metabolic Inhibitor. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with o
T2202 Lithocholic acid Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorpt
T2203 L-Carnitine hydrochloride The l-carnitine hydrochloride is a constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyper
T2204 Diaveridine Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studie
T2208 Zinc bacitracin Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=
T2210 Genipin Genipin, an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.
T2211 Dihydrostreptomycin sulfate Dihydrostreptomycin sulfate inhibits protein synthesis by binding to the 30S ribosomal subunit. Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic with bacte
T2212 Geniposide Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective,anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has be
T2214 Flumethrin Flumethrin is a pyrethroid insecticide. It is used externally in veterinary medicine against parasitic insects and ticks on cattle, sheep, goats, horses, and dogs, and the treatmen
T2217 Cephalomannine Cephalomannine is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.
T2218 8-Azaguanine 8-Azaguanine is a purine analogue with potential antineoplastic activity.
T2221 Uridine Uridine, a nucleoside, consists of uracil and D-ribose by a β-N1-glycosidic bond.
T2223 Kinetin Kinetin, a type of cytokinin, has plant growth regulation effects.
T2227 Hemicholinium-3 Hemicholinium-3 is a potent and selective choline uptake blocker.
T2228 Adipic acid Adipic acid is a precursor for the production of nylon.
T2229 Tetraethylenepentamine Pentahydrochloride Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.
T2238 Cariporide Cariporide (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activatio
T2265 PI3K-IN-2 PI3K-IN-2 is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta
T2267 BQU57 BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
T2282 RPI-1 RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. 
T2290 8-Hydroxyquinoline-2-carboxaldehyde N/A
T2291 2,8-Quinolinediol N/A
T2292 FPH2 FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
T2321 Protodioscin Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
T2340 AC1NS4RE It is a tyrosine kinase inhibitor.
T2371 Emapunil Emapunil is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
T2394 Pixantrone dimaleate Pixantrone dimaleate (BBR 2778 dimaleate) is an experimental antineoplastic drug.
T2423 P7C3-A20 P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and si
T2469 TP-808 Detail unknown.
T2476 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine Detail unknown.
T2534 Pitavastatin calcium Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of
T2538 Bimatoprost Bimatoprost is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension.
T2549 Robenidine hydrochloride Robenidine hydrochloride is an anticoccidial agent mainly used in poultry.
T2552 Succimer Succimer is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity.
T2554 Etofibrate Etofibrate is a combination of clofibrate and niacin, used to treat hyperlipemia.
T2556 Nandrolone decanoate Nandrolone Decanoate is the decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrol
T2563 O-Acetyl-L-carnitine hydrochloride O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of
T2587 Ecabet Sodium Ecabet sodium: a potential new agent in the management of distal colitis.
T2593 Eflornithine hydrochloride Monohydrate Eflornithine hydrochloride is a specific, irreversible inhibitor of ornithine decarboxylase.
T2607 MSDC-0160 MSDC-0160 is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
T2626 SBC-115076 SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
T2637 Exherin Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
T2648 Pimecrolimus Pimecrolimus, a calcineurin inhibitor immunosuppressant, binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction casc
T2690 Tranilast Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
T2691 Oritavancin diphosphate Oritavancin diphosphate is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections.
T2692 Dalbavancin Impurity Dalbavancin Impurity is effective against Gram positive bacteria.
T2698 Asperosaponin Ⅵ Akebia saponin D, the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
T2703 LED209 LED209, a specific inhibitor of quorum sensor QseC of GNB, can generate a multifunctional agent PAMAM-LED209.
T2712 Nifekalant hydrochloride Nifekalant hydrochloride is a pure potassium channel blocker and class III antiarrhythmic.
T2713 D-Stachyose tetrahydrate Stachyose is a tetrasaccharide consisting of two α-D-galactose units, one α-D-glucose unit, and one β-D-fructose unit sequentially.
T2715 Tubeimoside I Tubeimoside I(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).
T2716 1,3-Diphenylurea 1,3-Diphenylurea is involved with Epoxide hydrolase activity.
T2717 Salidroside Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
T2718 Palmatine chloride Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T2719 Succinic acid Succinic acid is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters
T2720 Ginsenoside Rc Ginsenoside Rc is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
T2722 Tetramethylpyrazine Tetramethylpyrazine (ligustrazine, TMP), a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) shows anti-inflammation, antioxidant, antiplate
T2723 Ketoisophorone Ketoisophorone is the major ingredients of saffron spice. It is a cyclic olefin and was reported as a product of the thermal degradation of β-carotene in aqueous suspension.
T2724 Caryophyllene oxide Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity.
T2726 Sinomenine Sinomenine is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
T2727 Salvianolic acid B Salvianolic acid B is an active pharmaceutical compound present in Salvia miltiorrhiza, exerts a neuroprotective effect in animal models of brain and spinal cord injury.
T2729 Scoparone Scoparone can be found in a number of food items such as sweet orange, wild celery, mandarin orange (clementine, tangerine), and lemon. It is found in the Chinese herb Artemisia sc
T2732 (-)-Epicatechin gallate Epigallocatechin gallate (EGCG) is the ester of epigallocatechin and gallic acid, and is a type of catechin with anti-inflammatory effects.
T2735 5-Acetylsalicylic acid Acetylsalicylic acid, also knows as aspirin, is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or r
T2736 Sodium Demethylcantharidate Demethylcantharidin (norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.
T2737 Neohesperidin Neohesperidin with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
T2739 Shikimic Acid Shikimic acid is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it.
T2740 Cinnamic acid Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.
T2744 Methyl Cholate Biotransformation of methyl cholate using Aspergillus niger was investigated.
T2745 Glycyrrhetinic acid Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which wa
T2746 Sophocarpine Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
T2747 Endothall The monohydrate is in the form of colorless crystals. Non corrosive. Used as a selective herbicide.
T2750 Ginkgolide C Ginkgolide C, a natural product, can enhance the cardiac function of rats in the body.
T2752 2'-Deoxyadenosine monohydrate Deoxyadenosine, a deoxyribonucleoside, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2
T2755 Rhoifolin Rhoifolin is extracted from Turpinia arguya Seem dried leaves.
T2756 Swertiamarin Swertiamarin is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.
T2758 Madecassic acid Madecassic acid is extracted from the whole herb of Centella asiatica.
T2760 3,5-Diiodotyrosine Dihydrate 3,5-Diiodotyrosine is a product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or
T2761 Naringin dihydrochalcone Naringin Dihydrochalcone(Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
T2763 Panaxadiol Panaxadiol is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.
T2766 Arctiin Arctiin acts on an agonists of the adiponectin receptor 1 with anti-cancer effects.
T2767 Neohesperidin Dihydrochalcone Neohesperidin dihydrochalcone(NHDC) is an artificial sweetener derived from citrus.
T2769 3-Aminopropionitrile fumarate 3-Aminopropionitrile fumarate is an organic compound and antirheumatic agent used in veterinary medicine.
T2770 Gentiopicrin Gentiopicroside, a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 µM and 22.8 µM for CYP2A6;
T2771 Orcinol glucoside Orcinol glucoside (OG), an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn, shows potent antioxidative and anxiolytic activities without sedative effec
T2772 S-allyl-L-cysteine S-Allyl cysteine (SAC), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.
T2773 Vindoline Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
T2774 Lycorine chloride Lycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
T2777 Ginsenoside Rg1 Ginsenosides are a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal
T2779 Olaquindox Store the product in sealed, cool and dry condition.
T2780 Catalpol Catalpol is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
T2783 Methyl Dihydrojasmonate Methyl dihydrojasmonate is an ester and a diffusive aroma compound, with the smell vaguely similar to jasmine. In racemic mixtures the odor is floral and citrus while epimerized mi
T2784 Orsellinic acid ethyl ester Orsellinic acid ethyl ester is a phenolic acid, extracted from lichens.
T2785 7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis.
T2787 Picroside I Picroside I, a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable an
T2788 Baccatin III Baccatin Ⅲ is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It has immunomodulatory and anticancer chemotherapeutic activities.
T2789 Scutellarin Scutellarin, an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Gird
T2790 Oridonin Oridonin is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9
T2791 Pectolinarin Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T2793 Tetrahydropalmatine Tetrahydropalmatine is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats.
T2794 Astilbin Astilbin is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
T2795 Amygdalin Amygdalin has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from interv
T2796 Coenzyme Q10 Coenzyme Q10 (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T2798 Esculetin Esculetin is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour
T2800 L-Theanine L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
T2801 Aristolochic Acid Aristolochic acids are a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.
T2804 Panaxtriol Panaxatriol can relieve myelosuppression induced by radiation injury.
T2805 Chlorogenic Acid Chlorogenic acid is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
T2806 Lappaconitine Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
T2807 Caffeic Acid Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
T2808 Bilobalide Bilobalide, a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.
T2810 (20S)-Protopanaxatriol (20S)-Protopanaxatriol(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
T2812 Adenosine disodium triphosphate Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.
T2813 Madecassoside Madecassoside is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activities.
T2815 Puerarin Puerarin, also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.
T2817 Picroside II Picroside II is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
T2820 Glycitin Glycitin, a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.
T2821 Ethyl ferulate Ethyl ferulate is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiprolifera
T2822 Ginsenoside Rb1 Ginsenoside Rb1 is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
T2823 Crocin Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional
T2824 Pedunculoside Pedunculoside is extracted from Ilex rotunda Thunb.
T2828 Spiculisporic Acid Spiculisporic acid is a bioactive γ-butenolide isolated from a marine Aspergillus.
T2829 Isoalantolactone Isoalantolactone, isolated from Inula spp., can inhibit the growth of several types of Y cells.
T2831 Glycocholic acid Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
T2832 S-Isocorydine(+) S-Isocorydine(+) and its derivatives have anticancer activities.
T2833 Dehydrocostus Lactone Dehydrocostus shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
T2835 Morin Morin was found to be a weak inhibitor of fatty acid synthase (IC50: 2.33 μM). Morin is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura
T2836 Isorhamnetin Isorhamnetin is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injur
T2837 Chrysin Chrysin exhibits many biological activities and pharmacological effects, including antioxidant, anti-inflammatory, anticancer, and antiviral activities.
T2839 Orsellinic acid Orsellinic acid is a phenolic acid extracted from lichens.
T2840 Phloracetophenone 2',4',6'-Trihydroxyacetophenone has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipa
T2842 Tangeretin Tangeretin, a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and
T2844 Hyperoside Hyperoside is a naturally occuring flavonoid compound which shows multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.
T2847 Indigo Indigo is extracted from Indigo blue.
T2849 Proanthocyanidins Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxyg
T2852 Citropten Citropten is a natural organic compound and is found in the essential oils of citrus such as lime, lemon, and bergamot.
T2856 Epicatechin (-)-Epicatechin is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
T2857 Gentisic acid Gentisic acid is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant propertie
T2860 Vanillyl Alcohol Vanillyl alcohol is derived from vanillin. It is used to flavor food. It has been used in trials studying the treatment of Smoking.
T2861 Tyrosol Tyrosol is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives.
T2862 Phloretic acid Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
T2863 p-Coumaric acid p-Coumaric acid is the abundant isomer of cinnamic acid, with antitumor and anti-mutagenic activities.
T2865 Oleanolic Acid Oleanolic acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.
T2866 Echinocystic acid Echinocystic acid (EA), a natural triterpone enriched in various herbs, shows a range of pharmacological activities including anti-inflammatory and antioxidant effects.
T2867 Diosgenin Diosgenin is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.
T2871 Quercitrin Quercitrin is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities. Quercitrin can be found in a number of food items such as garden tomato (va
T2872 Ginsenoside Re Ginsenoside Re may have properties that inhibit or prevent the growth of tumors.
T2875 Isopsoralen Angelicin, is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.
T2877 Mucic Acid Mucic acid is an aldaric acid obtained by nitric acid oxidation of galactose or galactose-containing compounds.
T2878 Ginsenoside Rd Ginsenoside Rd may have properties that inhibit or prevent the growth of tumors.
T2880 D-Cellobiose Cellobiose is a disaccharide, a reducing sugar, consists of two β-glucose molecules linked by a β(1→4) bond. It can be hydrolyzed to glucose enzymatically or with acid.
T2881 Ecdysterone 20-Hydroxyecdysone is a steroid hormone that regulates the processes of molting or ecdysis in insects.
T2882 Genistin Genistin is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities
T2883 Syringic acid Syringic acid (SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hyperg
T2886 Aleuritic Acid Aleuritic acid, or α-aleuritic acid, is a major ingredient in shellac, constituting about 35% of it. It is used as a starting material in the perfume industry for the preparation
T2887 Trigonelline Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
T2889 Isoferulic acid 3-Hydroxy-4-methoxycinnamic Acid exhibits hypoglycemic properties.
T2890 Hordenine Hordenine, an effective phenylethylamine alkaloid, has antibacterial activities.
T2894 Norcantharidin Norcantharidin is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.
T2896 Helenine Alantolactone(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator o
T2897 (±)-Shikonin Shikonin is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of
T2904 Sclareolide Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of S
T2905 5alpha-Cholestan-3-one 5alpha-Cholestan-3-one(5aCh3) is an intermediate product in cholesterol metabolism, which is elevated in the case of cerebrotendinous xanthomatosis. Within the cell, It is primaril
T2908 Palmitic acid Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
T2909 Fraxetin Fraxetin has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, ha
T2910 3-Hydroxyflavone 3-hydroxyflavone is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, an
T2912 Ergosterol Ergosterol is a steroid extracted from Ganoderma lucidum cystocarp.
T2913 Schisantherin A Schisantherin A is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.
T2914 Melibiose Melibiose is a reducing disaccharide formed by an alpha-1,6 linkage between galactose and glucose (D-Gal-α(1→6)-D-Glc).
T2916 Patchouli alcohol Patchouli alcohol is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions. Patchouli alcohol also suppresses inflammation induced
T2917 Tetrahydropalmatine hydrochloride Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo). It is a potent muscle relaxant.
T2918 Cholesteryl Acetate N/A
T2919 Sesamin Sesamin is a lignan extracted from Sesamum indicum L.
T2920 Berbamine dihydrochloride Berbamine dihydrochloride, a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.
T2926 Schizandrin A Schisandrin A is a main effective components extracted from the oriental medicine Schisandra chinensis, inhibits CYP3A activity with an IC50 of 6.60 μM and Ki of 5.83 μM, respect
T2927 Trigonelline hydrochloride Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
T2928 L-Rhamnose monohydrate α-L-Rhamnose monohydrate is a component of bacterial polysaccharides where it plays an important role in pathogenicity.
T2929 Ethyl Vanillate Ethyl vanillin, a vanillin analog, is a flavoring agent that exhibits strong antioxidant activity.
T2930 Alphalipoic acid Alpha-Lipoic Acid is a naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive acti
T2931 Citrulline Citrulline is an α-amino acid.
T2932 Ginsenoside Rh1 Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T2933 Wogonin Wogonin is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.
T2934 Bilirubin Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition.
T2935 Phenethylamine Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system.
T2936 3,4,5-Trimethoxyphenol Antiarol is a member of aromatic phenols and exhibits moderate DPPH free radical scavenging activity.
T2940 6-Hydroxyflavone 6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common
T2941 Glucosamine hydrochloride Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
T2942 Psoralen Psoralen is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
T2943 5-Hydroxymethyl-2-furaldehyde 5-Hydroxymethyl-2-furaldehyde is found from various carbohydrates.
T2945 Germacrone Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits the proliferation of
T2946 Tanshinone IIA sulfonate sodium Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human puriner
T2948 Ethyl vanillin acetate Vanillin is a phenolic aldehyde
T2950 Schisandrin Schisandrin is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.
T2951 Beta-Cyclodextrin Beta-Cyclodextrin is a member of the class of compounds known as oligosaccharides.
T2952 Camphor Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infective agent.
T2953 Ligustrazine hydrochloride Ligustrazine is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
T2954 Fructose Fructose is a simple ketonic monosaccharide extracted from Honey,fruits,berries,melon.
T2955 Gibberellic acid Gibberellic acid (also called Gibberellin A3, GA, and GA3) is a hormone found in plants and fungi.
T2956 Cedryl acetate Cedryl Acetate, an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functio
T2957 Arctigenin (-)-Arctigenin is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a ligna
T2958 Quinic acid Quinic acid is an acid which is found in cinchona bark and elsewhere in plants.
T2962 Dihydrocholesterol Dihydrocholesterol is a cholesterol derivative found in human feces, gallstones, eggs, and other biological matter.
T2963 Cholic Acid Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
T2964 Astragalus polyphenols Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.
T2965 Deoxycholic acid Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats f
T2967 Stigmasterol Stigmasterol is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol h
T2969 Lawsone Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of
T2971 Phytic acid Fytic acid is a complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
T2974 Cyclovirobuxin D Cyclovirobuxin D is extracted from Buxus microphylla.
T2976 L(-)-sorbose L(-)-sorbose is a ketose belonging to the group of sugars known as monosaccharides.
T2977 Acetylvanillin Vanillin is a phenolic aldehyde.
T2978 Mogroside V Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema model, and has the
T2979 DL-Menthol DL-Menthol is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis. (–)-Menthol is more common than (+)-menthol in natur
T2980 Chondroitine sulfate Chondroitin sulfate A is a derivatives of chondroitin extracted from shark bone which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. It reduces inflam
T2981 Xanthoxyline Xanthoxylin is a borneol and camphor tasting compound and can be found in a number of food items such as fats and oils, herbs and spices, pomegranate, and sweet orange. Derivatives
T2982 Xanthone Xanthone is currently used as ovicide for codling moth eggs and as a larvicide.
T2983 3,4,5-Trimethoxycinnamic acid 3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
T2986 Jatrorrhizine hydrochloride Jatrorrhizine hydrochloride is extracted from berberidis, radix.
T2987 Epigallocatechin (-)-Epigallocatechin is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils.
T2988 (-)-Epigallocatechin Gallate Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 rece
T2989 4-Hydroxybenzoic acid 4-Hydroxybenzoic acid is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more
T2997 Rheic Acid Rhein is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.
T2999 Gastrodin Gastrodin, an anti-inflammatory polyphenol, is extracted from Chinese natural herbal Gastrodia elata Blume. and benefits neurodegenerative diseases.
T2A2428 4-Methoxysalicylic acid 2-hydroxy-4-methoxybenzoic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(2-hydroxy-4-methoxyphenyl)propanoic acid. It is gen
T2A2476 L-Hydroxyprolin L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
T2A2497 glutamic acid (S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
T2A2509 Laurocapram Laurocapram is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a h
T2A2524 4-Methoxysalicylaldehyde 2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhi
T2A2532 histidine Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheat
T2A2537 Guanine Guanine is a purine base that is a constituent of nucleotides occurring in nucleic acids.
T2O2666 Methyl stearate Methyl stearate is found in cloves. Antifoaming agent and fermentation nutrient.
T2O2667 Methyl Oleate Methyl Oleate is an unsaturated high fatty acid ester, an important chemical raw material, widely used in the preparation of surfactants, leather additives, textile additives, as w
T2O2668 Oleic acid Oleic acid is an unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, an
T2O2680 Oxalic acid Oxalic acid is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolize
T2O2683 proline 1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline catalysed aldol con
T2O2701 L(+)-Ornithine hydrochloride L-ornithine hydrochloride has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the
T2O2707 D-(+)-Fucose 1. D-(+)-Fucose is a hexose deoxy sugar found on N-linked glycans that appears on the cell surface of mammalian and plant cells.
T2O2721 cysteine Cysteine is a naturally occurring, sulfur-containing amino acid which is important for protein synthesis, detoxification, and also exerts diverse metabolic functions.
T2O2728 glycine Glycine is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
T2O2730 serine Serine is a non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for
T2O2731 L-Aspartic acid Aspartic Acid is a non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the cit
T2O2770 Agarotetrol
T2O2774 L-Asparagine L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONI
T2O2776 L-Valine A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
T2O2777 threonine Threonine is an essential amino acid in humans (provided by food), Threonine is an important residue of many proteins, such as tooth enamel, collagen, and elastin. An important ami
T2O2791 Indole-3-acetic acid Indole-3-acetic acid (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.
T2O2798 D-Trehalose D-Trehalose can inhibit the decomposition of collagen, so it can be used to improve osteoporosis.
T2P2870 Damascenone Damascenone is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.
T2P2963 5-Methyl-7-methoxyisoflavone 1. 5-Methyl-7-methoxyisoflavone is used by bodybuilders for its ergogenic properties.
T2S0007 Sodium ferulic Sodium ferulate (SF), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent th
T2S0029 4'-Demethylpodophyllotoxin 4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
T2S0122 Mandelic acid It has the health function of killing sperm, reducing Yin, inhibiting bacteria, anti-inflammation and enhancing vagina self-cleaning.
T2S0157 Methyl hexadecanoate Used as an intermediate of emulsifier, wetting agent, stabilizer and plasticizer.
T2S0164 Palmitic acid ethyl ester Used as softener and lubricant.
T2S0257 Dehydroandrographolide succinate Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection.
T2S0265 Robinin Biochem/physiol Actions Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol. The ability of robinin to reverse the multidrug resista
T2S0287 Araloside V Araloside V comes from the roots of Aralia elata. It can be used to treat neurasthenia.
T2S0357 6-Hydroxycoumarin 6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a human CA9, CA12 inhi
T2S0389 Emodin-1-O-β-D-glucopyranoside 1. Emodin 1-O-beta-D-glucoside has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin 1-O-beta-D-glucoside shows inhibitory
T2S0461 D-Arabinose Inexpensive starting material for chiral synthesis.
T2S0490 Eugenol acetate Eugenol Acetate is a constituent of Clove oil, an essential oil from the clove plant, Syzygium aromaticum. Clove oil is a natural analgaesic and antiseptic used primarily in dentis
T2S0500 Ilexsaponin A1 1. Ilexsaponin A shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.
T2S0531 Pinoresinol dimethyl ether
T2S0618 β-Elemonic Acid 1. Beta-Elemonic acid exhibits anti-inflammatory effects. 2. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of bet
T2S0633 Raspberry ketone 1. 4-(4-Hydroxyphenyl)-2-butanone(RK) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the
T2S0690 Ecliptasaponin A 1. Ecliptasaponin A has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epith
T2S0712 Sinigrin Sinigrin, a glucosinolate, is used as a systrate to identify, differentiate and characterize myrosinase(s)/thioglucoside glucohydrolase(s)/thioglucosidase(s). Sinigrin is used as a
T2S0842 Scutellarin methylester Scutellarin methylester has the effect of improving sleep, such as prolonging sleep time, increasing the incidence of sleep, shortening sleep latency, which also helps to delay agi
T2S0843 Negletein 1. Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth
T2S0850 Malic acid 1. Malic acid did reduce populations of L. monocytogenes on poultry. 2. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtu
T2S0961 Chalcone Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
T2S0973 2-Methoxycinnamic acid 1. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity.
T2S1158 4,5-Dicaffeoylquinic acid 1. Isochlorogenic acid C(4,5) has antiviral activity, including anti-HIV-1 integrase activity. 2. Isochlorogenic acid C(4,5) shows anti-hepatotoxic activity.
T2S1464 Thiocolchicoside Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine
T2S1625 Ethyl 4-methoxycinnamate 1. Ethyl 4-methoxycinnamate is an anticarcinogenic agent. 2. Ethyl 4-methoxycinnamate is a glutathion S tranferase inhibitor.
T2S1720 Huperzine B 1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's diseas
T2S1778 Goitrin 1. Goitrin is a potent antithyroid compound found naturally in crucifers. 2. Goitrin is responsible for the induction of glutathione S-transferases.< 3. Goitrin is a moderate in
T2S1837 Steviol 1. Steviol, a natural sweetener, it inhibits proliferation of the gastrointestinal cancer cells intensively. 2. Steviol can induce a significant increase in CYP3A29 expression. 3.
T2S1840 Rebaudioside D Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degra
T2S1841 Tenacigenin B, 3-O-β-Allopyranosyl-(1→4)
T2S1992 Perillartine Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.
T2S2003 Phlorizin dihydrate 1. Phlorizin dihydrate can significantly inhibit oxidative DNA damage.
T2S2018 7-beta-Hydroxylathyrol 7β-Hydroxylathyrol is a diterpenoid extract from the seed oil of Caper Spurge and displays P-gp inhibition resulting in cytotoxic properties.
T2S2043 Dracorhodin perochlorate Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for an
T2S2108 Coixol 1. Coixol acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to
T2S2109 Skimmianin 1. Skimmianin is a spasmolytic agent. 2. Skimmianin shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
T2S2150 Noricaritin
T2S2169 Naringenin trimethyl ether 1. Naringenin trimethyl ether shows significant molluscicidal activity with a median lethal concentration (LC(5)) of 3.9 μg/mL.
T2S2172 nerolidol 1. Nerolidol shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. 2. Nerolidol is mainly related to ROS and DNA single st
T2S2173 Naringenin chalcone 1. Naringenin chalcone has antiallergic activity 2. Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. 3. Naringenin chalco
T2S2215 Crebanine 1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibril
T2S2295 Timosaponin A1 Timosaponin A1 is a coprostane type steroidal saponin isolated from Rhizoma Anemarrhenae.
T2S2335 Dehydroevodiamine Dehydroevodiamine, a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide
T2S2362 Dehydrocorydaline nitrate 1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber
T3003 5-hydroxytryptophan 5-Hydroxytryptophan is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
T3004 Batyl alcohol Batyl alcohol, isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
T3005 4-Hydroxychalcone 4-Hydroxychalcone attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
T3006 Cinnamylideneacetic acid JUAREZIC ACID is also known as 5-Phenylpenta-2,4-dienoic acid.
T3007 Spermine Spermine is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.
T3009 Bovinocidin Bovinocidin is an irreversible inhibitor of succinate dehydrogenase.
T3010 Xanthurenic Acid Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).
T3011 Kynurenine Kynurenine is synthesized by the enzyme tryptophan dioxygenase.
T3012 Mangiferin Mangiferin is used for antidiabetes. Extracted from Mangifera indica L..
T3013 Catharanthine tartrate Extracted from whole herb of Catharanthus roseus (L.)G.Don;Store the product in sealed, cool and dry condition.
T3014 Abscisic acid Abscisic acid is a compound isolated from fruits and plants.
T3016 Melezitose Melezitose is a nonreducing trisaccharide sugar that is produced by many plant sap-eating insects, including aphids such as Cinara pilicornis by an enzyme reaction.
T3018 Protocatechualdehyde Protocatechualdehyde, a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been
T3019 Rheochrysidin Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and
T3020 Sclareol Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines.
T3033 Deoxycorticosterone acetate Desoxycorticosterone acetate is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
T3034 Eprazinone dihydrochloride Eprazinone is a mucolytic with antitussive and mucolytic effect.
T3039 Hederagenin Hederagenin is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.
T3040 Gallein Gallein is a small molecule inhibitor of Gβγ activity.
T3052 Sancycline sancycline is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA int
T3054 Daurisoline Daurisoline is a hERG inhibitor and also an autophagy blocker.
T3055 Liensinine Perchlorate Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
T3056 Bavachinin Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae with potent anti-angiogenic activity.
T3093 Spermine Tetrahydrochloride Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical atta
T3097 Mycophenolic Acid Impurity Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of
T3106 C-DIM12 C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and e
T3110 PRT 4165 PRT4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation.
T3114 Povidone-iodine Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated
T3115 Nicarbazin Nicarbazin is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. A coccidiostat for poultry.
T3124 Carbendazim Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim ap
T3127 Glycinamide Hydrochloride Glycinamide Hydrochloride is a glycine pro-drug.
T3136 Methylcobalamin Methylcobalamin is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in cli
T3138 Astaxanthin Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in
T3141 Bendazac L-lysine Bendazac L-Lysine is an agent introduced for the management of cataracts, protecting the level of vision in patients, thus delaying the need for surgical intervention.
T3145 D-(+)-Trehalose dihydrate Trehalose is a natural α-linked disaccharide formed by an α,α-1,1-glucoside bond between two α-glucose units.
T3149 Salvianolic Acid C Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia.
T3151 Brassinolide Brassinolide is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
T3152 Harmol Harmol is a β-carboline isolated from nature.
T3154 Citral Citral is a clear yellow colored liquid with a lemon-like odor. Less dense than water and insoluble in water. Toxic by ingestion. Used to make other chemicals.
T3158 Harmane Harmane is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T3159 Guaiazulene Guaiazulene belongs to the class of organic compounds known as guaianes.
T3160 HUHS015 HUHS015 is a potent PCA-1/ALKBH3 inhibitor.
T3161 BACE-IN-1 BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor
T3162 IDE1 IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mou
T3168 MN-64 MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
T3173 DAA1106 DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor.
T3189 CTLA-4 inhibitor CTLA-4 inhibitor is a potent CTLA-4 inhibitor.
T3191 Cyantraniliprole Cyantraniliprole(HGW-86) is an insecticide of the ryanoid class.
T3202 Fluensulfone Fluensulfone is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target insects and mammals.
T3203 Methyl 13-cis-4-Oxoretinoate 4-Keto 13-cis-Retinoic Acid is a retinoic acid metabolite in neuroblastoma.
T3208 Brevianamide F Brevianamide F, also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance prot
T3211 Midostaurin PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor rec
T3213 Hematoporphyrin dihydrochloride Hematoporphyrin dihydrochloride is a substrate for affinity chromatography of heme-binding proteins.
T3216 Selexipag Selexipag(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the therapy of pulmonary arterial hypertension (PAH).
T3219 16,17-Epoxypregnenolone acetate 16,17-Epoxypregnenolone acetate can be produced by Burkholderia cepacia SE-1.
T3220 Euphorbiasteroid Euphorbiasteroid (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.
T3221 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile Detail unknown.
T3222 16,17-Epoxypregnenol N/A
T3223 16beta-Methyl-16alpha,17alpha-epoxypregnenolone N/A
T3225 16,17-Epoxy-21-acetoxypregnenolone N/A
T3227 Danshensu Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.
T3228 D-fructose-1,6-diphosphate N/A
T3231 Niraparib MK-4827(Niraparib) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective agains
T3232 Higenamine Hydrochloride Higenamine(Hydrochloride) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein–coupled receptors,
T3233 Sophoricoside Sophoricoside is effective against inflammation and can reduce the GPT.
T3234 Dihydroactinidiolide Dihydroactinidiolideis avolatileterpene. It has a sweet,tea-likeodorand is used as a fragrance.
T3235 Rebaudioside A Rebaudioside A is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.
T3236 Solanesol Phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.
T3237 L-α-Phosphatidylcholine Typical lots of egg yolk phosphatidylcholine have fatty acid contents of approximately 33% 16:0 (palmitic), 13% 18:0 (stearic), 31% 18:1(oleic), and 15% 18:2 (linoleic) (other fatt
T3238 Lanolin Lanolinis a wax secreted by the sebaceous glandsofwool-bearing animals.
T3239 Geranyl Tiglate Geranium oil is one of the most important natural perfume.
T3240 Citronellol Citronellol is used in insect repellents and perfumes and as a mite attractant.
T3242 Breviscapin Breviscapine is the total flavonoid components (the content of scutellarin > or =85%) extracted from the dried whole plant of Erigeron breviscapus.
T3243 Betaine Betaine is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and
T3244 N-Sulfo-glucosamine sodium salt N-Sulfo-glucosamine sodium salt is possible to effect reaction at arthritis.
T3245 (S)-(+)-Carvone (S)-(+)-Carvone is the main constituent of caraway oil and pineapple seed oil.
T3246 Tabersonine Tabersonineis a terpene indole alkaloid found in the medicinal plant Catharanthus roseus.
T3247 Lysozyme Lysozyme is a bactericidal enzyme present in the chicken eggwhite, and it lyses gram-positive bacteria.
T3248 alpha-Boswellic acid Boswellic acids are a series of pentacyclic triterpene molecules that are produced by plants in the genus Boswellia.
T3249 Calcium carbonate Calcium Carbonate is the carbonic salt of calcium (CaCO3).
T3250 10-Hydroxy-2-decenoic acid 10-Hydroxy-2-decenoic acid is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
T3251 Stachydrine Hydrochloride Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.
T3252 Triacontanol 1-Triacontanol is a fatty alcohol of the general formula C30H62O, also known asmelissyl alcoholormyricyl alcohol. It is found in plantcuticle waxesand inbeeswax. Triacontanol is ag
T3253 Castor oil Castor Oil is a vegetable oil pressed from the seeds of the castor bean, Ricinus communis, used as a laxative and as an excipient in medicinally.
T3254 PHYTOL Phytol, a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory a
T3256 MonoMethyl auristatin F Monomethyl auristatin F, an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
T3262 Creatine phosphate disodium salt Creatine phosphate is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain.
T3264 Etilefrine hydrochloride Etilefrine hydrochloride is a phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.
T3266 Lumefantrine Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy e
T3270 Dihydralazine sulphate Dihydralazine sulphate is an antihypertensive agent.
T3271 Zinc Orotate Orotic acid zinc salt dihydrate is an intermediate product in pyrimidine synthesis.
T3273 Bifendatatum Bifendatatum is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.
T3276 Benorilate Benorylate is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
T3282 Trimeprazine tartrate Trimeprazine tartrate is aphenothiazine derivative that is used as an antipruritic. It also acts as a sedative,hypnotic, and antiemetic for prevention of motion sickness.
T3283 Cetilistat Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
T3285 Eslicarbazepine Acetate Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are
T3286 Sodium picosulfate monohydrate Sodium picosulfate monohydrate increases secretion of water and electrolytes and inhibits their absorption.
T3287 Octenidine Dihydrochloride Octenidine is an antibiosis.
T3288 Sulfisomidine Sulfisomidine is a sulfanilamide antibacterial agent.
T3289 Amifostine Amifostine anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.
T3290 Pikamilone Pikamilone is an intelligent medicine.
T3295 1-Methyl-1H-pyrazol-3-amine 1-Methyl-1H-pyrazol-3-amine is a chemical compound.
T3313 D-Luciferin D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening ap
T3314 Perillyl alcohol Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferas
T3315 Benurestat Benurestat is a urease inhibitor.
T3316 Fluoromethalone Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone a
T3317 SZL P1-41 SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF
T3321 Oleanonic Acid Oleanolic acid is relatively non-toxic,hepatoprotective, and exhibits antitumor and andantiviral properties.
T3322 Chalcone trans-Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
T3323 Ursonic Acid Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
T3324 Lycorine Lycorine inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T3328 Angelic Acid Angelic acid is a monocarboxylic unsaturated organic acid. Angelic acid esters are the active components of herbal medicine used against a wide range of various health disturban
T3329 4',7-Dimethoxyisoflavone 4',7-dimethoxyisoflavone, a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.
T3330 Trimethoxystilbene 3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast Y cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and
T3331 (1R,2R)-Trans-N-Boc-1,2-Cyclohexanediamine Cyclohexanediamine has a potential of anticancer activity.
T3336 Rg3039 RG3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both
T3343 5-methoxyflavone 5-methoxyflavone is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.
T3344 Ciwujianoside-B Ciwujianoside-B is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition.
T3361 Cambendazole Cambendazole is one of the most effective agents for the therapy of human strongyloidiasis. Cambendazole is a nematocide effective against a variety of gastrointestinal parasites i
T3362 Eupatilin Eupatilin, a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.
T3364 Veratramine Veratramine(NSC17821; NSC23880) is a potent signal transduction inhibitor for treating tumors.
T3365 Rebaudioside C Dulcoside B (Rebaudioside C) is a natural sweeteners used for diabetics and others on carbohydrate-controlled diets.
T3367 Macranthoidin B Macranthoidin B, a saponin extracted from Flos Lonicerae is a main bioactive saponin in rat plasma (p.o.).
T3368 Alpha-Hederin Alpha-hederin is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.
T3370 Hederacoside C Hederacoside C is expectorant for Cold and cough relief, Bronchitis.
T3371 Quillaic Acid Quillaic acid is the major aglycone of the saponins in the Chilean indigenous tree Quillaja saponaria Mol.
T3372 Dipsacoside B Dipsacoside B is a major bioactive saponin used as a marker.
T3373 Columbianadin Columbianadin, one of the main bioactive constituents of the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan, has been found to possess obvious pharmacological effects
T3376 Cynaroside Cynaroside is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
T3381 Lysionotin Lysionotin has expectorant, eliminating phlegm, softening effects.
T3382 Wilforlide A Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. High-dose wilforlide A has obvious anti-inflammatory effect, but has no signific
T3383 Cimifugin Cimifugin inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1,1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free
T3389 TRX818 TRX-818 is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
T3392 Sinapine thiocyanate Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a pheno
T3393 Triptophenolide Triptophenolide is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.
T3394 Timosaponin BII Timosaponin BII has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1
T3397 Epimedin C Epimedin C was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. It has potential
T3399 Psoralidin Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T3405 6-Gingerol 6-Gingerol, an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other ti
T3407 Rapastinel Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T3409 Plantamajoside Plantamajoside has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.
T3413 5-O-Methylvisammioside 5-O-Methylvisammioside is a natural compound that isolated from the famous Chinese herbal medicines, Saposhnikovia divaricata (Turcz.) Schischk.
T3414 Morroniside Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human um
T3424 Ezutromid Ezutromid is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, incr
T3425 Polyphyllin VII Polyphyllin VII, the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, ce
T3428 Helicid Helicid is a medicine available in a number of countries worldwide.
T3436 LYS01 LYS01 free base is a new lysosomal autophagy inhibitor.
T3438 S107 S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
T3439 ML348 ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).
T3443 Argiprestocin Vasopressin, also called antidiuretic hormone that plays a key role in maintaining osmolality. It is a neurohypophysial hormone found in most mammals. Drugs used to cause const
T3445 Importazole Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
T3448 GJ103 GJ103 sodium salt is an active analog of the read-through compound GJ072. Some GJ072 analogs (e.g., GJ103, GJ106, GJ109, and GJ111) consistently demonstrates their activities in al
T3459 VK3-OCH3 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
T3465 Vesnarinone Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic
T3475 MD 39-AM Anticytokinin activity was evaluated by 50% of the callus growth on the medium with kinetin but without anti-cytokinin
T3485 Probimane Probimane had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.
T3487 HSP70-IN-1 HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).
T3493 Clofentezine Clofentezine is an active substance of plant protection product used as the pesticide, acaricide.
T3496 Buprofezin Buprofezin is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.
T3499 Remodelin Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.
T3501 Colistimethate Sodium Colistimethate Sodium is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options.
T3503 MC-Val-Cit-PABC-PNP MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein
T3505 tert-Butyl ((3-hydroxyazetidin-3-yl)methyl)carbamate tert-Butyl ((3-hydroxyazetidin-3-yl)methyl)carbamate is an active biochemical agent.
T3507 2-CHLORO-5-CYANOPYRAZINE 2-CHLORO-5-CYANOPYRAZINE is an active biochemical.
T3510 Olumacostat Glasaretil Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
T3524 Halofuginone hydrobromide Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumo
T3532 5S rRNA modificator 5S rRNA modificator, used in 5S rRNA RNA modification, is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules.
T3544 SHP099 hydrochloride SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
T3549 Avadomide CC-122 is an orally available pleiotropic pathway modulator with potential antineoplastic activity.
T3562 Valrocemide Valrocemide, also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is
T3563 Lvguidingan Lvguidingan is an Anticonvulsant agent.
T3567 SU 4942 SU 4942 is a bioactive chemical.
T3568 SU 4313 SU 4313 is a bioactive chemical.
T3569 SU 5214 SU 5214 is a modulator of tyrosine kinase signal transduction.
T3571 NSC 247030 NSC 247030 is a biochemical.
T3572 1,3-Bis(4-aminophenyl)urea 1,3-Bis(4-aminophenyl)urea can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.
T3573 Benthiazole Acticide WB 300 is an antiseptic.
T3574 Sematilide HCl Sematilide (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial m
T3575 Acecainide hydrochloride Acecainide hydrochloride is a major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
T3578 Pyridoxal phosphate Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, deca
T3592 MQAE MQAE, a fluorescent chloride ion indicator, is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is quenched via colli
T3601 Benodanil BENODANIL is a kind of fungicide.
T3602 D-Pantothenic acid sodium salt Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin. For many animals, pantothenic acid is an essential nutrient. Animals require pan
T3605 Gastrodenol Gastrodenol is a bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease.
T3606 Gamma-Oryzanol Gamma-Oryzanol is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in
T3607 Kitasamycin Kitasamycin is a macrolide antibiotic.
T3609 Dioxopromethazine Dioxopromethazine is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia.
T3611 Sodium Glucuronic Acid Sodium Glucuronic Acid is used in the treatment of hepatitis and liver cirrhosis.
T3612 Carbocisteine Carbocysteine is a compound formed when the iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expector
T3615 Evofosfamide Evofosfamide is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM) conjugated with 2-nitroimidazole, with potential antineoplastic activity. When
T3616 Carbazochrome Carbazochrome is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, cea
T3628 Madrasin Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
T3629 Gamithromycin Gamithromycin is a macrolide compound with antibacterial activity.
T3635 IQ-1 Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates
T3642 TBA-354 TBA-354 is a potent anti-tuberculosis compound.
T3643 HMN-176 HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).
T3647 HTHQ HTHQ, a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevate
T3651 YM-58483 YM-58483 is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.
T3654 APY29 APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
T3657 Dcimc chloride 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride has antibiotics activity.
T3658 TAS-102 TAS-102 is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
T3667 Dehydroandrographolide Succinate Potasium Salt Dehydroandrographolide Succinate Potasium Salt is a natural compound with anti-virus infection activity.
T3670 Forsythoside A Forsythoside A has antimicrobial, anticomplementary, anti-inflammatory and antiendotoxin activities. Forsythoside A inhibits Infected cells was confirmed by infecting primary chick
T3671 Vitexin-2''-O-rhamnoside Vitexin-2''-O-rhamnoside is a compound contributes to the protection against H₂O₂ -mediated oxidative stress damage.
T3675 1-Deoxynojirimycin 1-Deoxynojirimycin is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.
T3680 ISO-1 ISO-1 is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages.
T3681 4-Cyclohexylphenol 4-Cyclohexylphenol is a biochemical compound for proteomics research.
T3693 7-Bromo-2,4-diaminoquinazoline 7-Bromo-2,4-diaminoquinazoline is an active biochemical.
T3695 Pepstatin Pepstatin is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin.
T3696 polygalaxanthone III Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
T3702 CHIR-090 CHIR-090 is a very potent and selective LpxC inhibitor with antibiotic activity.
T3718 α-santonin α-santonin is a potent antiparasitic agent.
T3731 Hydrocinnamic acid Phenylpropanoic acid or hydrocinnamic acid is a carboxylic acid belonging to the class of phenylpropanoids. It is a white, crystalline solid with a sweet, floral scent at room temp
T3733 Methyl 4-hydroxycinnamate Methyl trans-p-Coumarat is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of methyl 3-phenylprop-2-enoate.
T3735 Tetrahydro Curcumin Tetrahydrocurcumin, a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.
T3739 2,6-Dimethoxyquinone 2, 6-dimethoxy-1, 4-benzoquinone is a member of the class of compounds known as P-benzoquinones. 2, 6-dimethoxy-1, 4-benzoquinone is slightly soluble (in water) and an extremely we
T3740 Isovanillin Isovanillin is a reversible inhibitor of aldehyde oxidase. It is largely used as pharmaceutical intermediates and also applied in food and beverage industry, synthetic fragrances,
T3742 3-Methylcatechol 3-Methylcatechol is an active biochemical.
T3744 Veratric acid Veratric acid is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.
T3745 3,4-Dimethoxyphenol 3,4-Dimethoxyphenol is an active biochemical.
T3746 Avolin Dimethyl phthalate has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in human
T3747 syringaldehyde Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehy
T3748 orcinol Orcinol glucoside is anxiolytic agent without sedative effect.
T3749 Pyrogallol Pyrogallol is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.
T3750 Piceol 4'-Hydroxyacetophenone is a potent xanthine oxidase inhibitor.
T3751 Resacetophenone 2', 4'-dihydroxyacetophenone is a member of the class of compounds known as alkyl-phenylketones.
T3752 4-Hydroxybenzyl alcohol 4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt
T3753 Sinapinic Acid Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cyt
T3754 Hydrocinnamic alcohol Hydrocinnamic alcohol exists in storax and fern balsam, also present in Vaccinium species fruits, guava fruit and peel, blackberry, other fruits, rum, white wine, shitake mushroom,
T3755 Pinostilbene Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA.
T3756 Allitol Allitol is a substrate for the production of L-form ketoses and aldoses.
T3758 2,6-Dimethoxybenzoic acid 2,6-Dimethoxybenzoic acid is an active biochemical.
T3760 2'-Hydroxy-5'-methoxyacetophenone 2'-Hydroxy-5'-methoxyacetophenone is an active biochemical.
T3761 1-Octacosanol 1-Octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. It is reported to possess cholesterol-lowering effects, antiag
T3762 Hyaluronic acid Hyaluronic Acid is a glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that is a component of connective tissue, skin, vitreous humour
T3763 Fumaric acid Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as a
T3764 Miraculan Triacontan-1-ol is an active biochemical
T3769 Tenuifolin Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
T3773 Oxypaeoniflorin Oxypaeoniflorin is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba.
T3775 Armepavine Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBP pathways. It improves experimental autoimmune crescentic glomer
T3778 Pueraria glycoside Pueraria glycoside shows marked peroxynitrite.
T3779 Crocin II Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein express
T3780 Oroxin B Oroxin B has antioxidant activity.
T3781 Jujuboside B Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.
T3783 Fraxin Fraxin is a glucoside of fraxetin.
T3784 Griffonin Lithospermoside has anti-oxidant, anti-tumor promoting activities.
T3787 Didymin Didymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potent
T3792 Ajugol Ajugol shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).
T3793 (20R)-Ginsenoside Rh1 20S, 20R ginsenoside-Rh1 can inhibit the thrombin-induced conversion of fibrinogen to fibrin.
T3794 1,2,3,4,6-O-Pentagalloylglucose 1,2,3,4,6-Pentagalloylglucose and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose (PGG) possesses pot
T3795 Corilagin Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro. Corilagin can enhance the cytotoxicity of b
T3798 Zigu-glucoside I Ziyuglycoside I has anti-inflammatory activity, could be used as an active ingredient for cosmetics.
T3799 Isorhamnetin 3-O-neohesperidin Isorhamnetin 3-O-neohesperidine is a flavonol glycoside extract used as an anti-oxidant.
T3800 Typhaneoside Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.
T3801 Byakangelicin Byakangelicin is an antineoplastic agent.
T3802 Ligustroflavone Ligustroflavone has anti-inflammatory activity.
T3803 Nuezhenide Nuezhenide significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a cl
T3804 Neomangiferin Neomangiferin has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a
T3807 (-)-Gallocatechin gallate (-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.
T3808 Icariside I Icariin is isolated from Epimedium herb. It can stimulate osteogenic differentiation of BMSCs and inhibit bone resorption activity of osteoclasts.
T3809 Liriope muscari baily saponins C Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.
T3810 Saikosaponin B2 Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces di
T3812 20(R)-Propanaxadiol 20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.
T3814 Isorhapontigenin Isorhapontigenin is a tetrahydroxylated stilbenoid with a methoxy group. It is an isomer of rhapontigenin and an analog of resveratrol. It is found in the Chinese herb Gnetum cleis
T3815 Isoscopoletin 6-Hydroxy-7-methoxycoumarin is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
T3817 Darutigenol Darutigenol has obvious antithrombotic effect,its mechanism may be related to inhibition of platelet aggregation and adhesion.
T3820 Iridin Iridin is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment
T3823 D-Pinitol D-Pinitol has anti-inflammatory activity. D-Pinitol exerts insulin-like activity, used for many diabetic associated conditions. D-Pinitol is a safe nutrient to reduce calorie consu
T3828 (-)-Gallocatechin (-)-Gallocatechin has free radical scavenging ability and moderate affinity to the human cannabinoid receptor.
T3843 Pinosylvin Pinosylvin induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.
T3847 Asperuloside Asperuloside has anti-inflammatory activity.
T3848 7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside 7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside is a natural product from Astragalus membranaceus
T3850 Luteolin-7-glucuronide Luteolin-7-Glucuronide possesses antioxidant activities.
T3858 macranthoidin A Macranthoidin A has anti-inflammation activity.
T3861 Isobacachalcone Isobavachalcone is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with infl
T3866 Anwuligan Anwuligan is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.
T3869 Skimmin Skimmin has anti-inflammatory activity, can significantly improve renal function and suppress the IgG deposition as well as the development of glomerular lesions in a rat model of
T3873 griffonilide Griffonilide is an extract from the Semiaquilegia adoxoides root, a traditional anticancer herb.
T3874 Diosgenin glucoside Diosgenin glucoside and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significant inhibition of Di
T3875 CLINODISIDE A Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.
T3876 Loureirin B Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fi
T3882 glucosylvitexin Glucosylvitexin inhibits TPO activity.
T3885 ROSIRIDIN Rosiridin has cardioprotective activity.
T3888 Scopolin Scopolin formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis,and this compound
T3890 Verbenalin Verbenalin induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
T3894 Chonglou Saponin II Chonglou Saponin II has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.
T3895 Polyphyllin I Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cl
T3898 Schaftoside Schaftoside has antioxidant and anticancer activity.
T3900 Emodin-8-glucoside Emodin-8-beta-D-glucoside functions to protect from focal cerebral injury induced by ischemia and reperfusion. Emodin-8-beta-D-glucoside directly stimulates cell proliferation and
T3901 Solasonine Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.
T3906 Epimedin A Epimedin A has anti-osteoporosis activities in vivo.
T3911 Anemoside A3 Anemoside A3 is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative disea
T3918 Ginsenoside Rb3 Ginsenoside Rb3 is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS m
T3919 Ginsenoside Rb2 Ginsenoside Rb2 found in species of Panax, upregulating GPR120 gene expression.
T3920 Pseudoginsenoside F11 Pseudoginsenoside-F11 is a component of Panax quinquefolium (American ginseng), can antagonize the learning and memory deficits induced by scopolamine, morphine, and methamphetamin
T3922 Complanatoside A Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus.
T3925 Astragaloside I Astragaloside I is a natural product isolated from Astragalus.
T3931 Isobavachin Isobavachin can facilitate mouse ES cells differentiating into neuronal cells.
T3934 Isavuconazonium sulfate Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lan
T3939 Benzoin The main uses of benzoin are as a precursor to benzil, which is a photoinitiator.
T3941 Choline Fenofibrate Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
T3946 Caprylic acid Caprylic acid is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid taste that is minimally soluble in water. Caprylic acid is used
T3947 Nonanoic acid Nonanoic acid is a fatty acid which occurs naturally as esters are the oil of pelargonium. Synthetic esters, such as methyl nonanoate, are used as flavorings. Pelargonic acid is an
T3948 Hendecanoic acid Hendecanoic acid appears to be involved in the control of triacylglycerol synthesis. It is found in breast milk produced by women in the United States, in infant formulas, in semin
T3949 Myristic acid Myristic Acid, a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by
T3950 Tridecanoic acid Tridecanoic acid is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been identified as a substrat
T3952 TPEN TPEN is a specific cell-permeable heavy metal chelator.
T3954 Adelmidrol Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
T3956 ETH2120 Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
T3964 Glutaminase C-IN-1 Glutaminase C-IN-1 is a Glutaminase C allosteric inhibitor.
T3966 Tirasemtiv Tirasemtiv(CK 2017357) is a small-molecule fast-skeletal-troponin activator, with a potential treatment for muscle weakness and neuromuscular dysfunction.
T3976 Cytosporone B Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent ge
T3982 Vulpinic Acid Vulpinic Acid is a lichen metabolite with anti-inflammatory,antibacteria, properties,plant growth inhibitor.
T3984 GLP-1(7-36) GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic ef
T3995 Amcasertib Amcasertib is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.
T3A2414 Manninotriose Manninotriose has the pharmacological activities, such as promoting the proliferation of hematopoietic cells, improving immunity, lowering blood glucose and anti-tumor.
T3A2467 Allocryptopine Allocryptopine induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
T3O2709 Bronze Red
T3O2749 L-Leucine Leucine is one of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulatio
T3O2784 Vitamin B6 Vitamin B6 is a component of some coenzymes in human body, which is involved in a variety of metabolic reactions, especially related to amino acid metabolism.Clinical application o
T3P2904 Linolenic acid Linolenic Acid is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis
T3S0013 Ethyl caffeate 1. Ethyl caffeate has anti-inflammatory activity. 2. Ethyl caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl caffeate is a pote
T3S0057 Dihydrochelerythrine 1. Dihydrochelerythrine is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potenti
T3S0081 Oxypeucedanin 1. Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of
T3S0128 Hydroprotopine Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.
T3S0136 O-Methylbroussochalcone B
T3S0156 Atractyloside potassium salt 1. Atractyloside potassium salt inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.
T3S0175 Crocin I 1. Crocin I has anti atherosclerosis and hypolipidemic effects.
T3S0205 Beta-Hederin 1. Beta-Hederin has antileishmanial activity. 2. Beta-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer.
T3S0208 Hederagenin-28-beta-D-glucopyranoside Used for content determination, identification, pharmacological experiment, activity screening, etc.
T3S0218 Thonningianin A 1. Thonningianin A has anti-cancer activities. 2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor. 3. Thonningianin A has antioxidant property,
T3S0237 Precyasterone
T3S0309 Raffinose 1. After treatment with CVGI, Raffinose family oligosaccharide was hydrolyzed effectively to yield galactose and sucrose. 2. AA-PCD resistance in Raffinose-grown cells occurs with
T3S0335 Soyasaponin Bb 1. Soyasaponin Bb can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activatin
T3S0401 Piceatannol 3'-O-glucoside Piceatannol 3'-O-glucoside increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema,so it can protect lung injury.
T3S0488 Syringaresinol-di-O-glucoside 1. Syringaresinol-di-O-glucoside protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memo
T3S0507 Homovanillic acid 1. Homovanillic acid is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain. 2. Abnormalities in white matter were associated with lo
T3S0601 Buddlejasaponin IVb 1. Buddlejasaponin IVb(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.
T3S0626 Denudatine 1. Denudatine has effects on action potential of ventricular fibers and has inhibition on arrhythmogenic action of aconitine.
T3S0629 Delsoline 1. Delsoline has hypotensive effects.2. Delsoline is not only effective in preventing ventricular fibrillation and arrythmia, but can raise the intebsity of the threthold of electr
T3S0640 Glycerol trioleate Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
T3S0645 Feruloyltyramine 1. N-trans-Feruloyltyramine(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes
T3S0693 Blinin Blinin, isolated from the whole plant of Conyza blinii, is used in folk medicine in the south-west of China.
T3S0804 Worenine Worenine is used in the a flurophore switched probe which aids in correction of an abasic site (AP site) caused by the removal of a damaged base in DNA.
T3S0895 Spirostan-3-ol Spirostan-3-ol is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis.
T3S1089 Phillygenin 1. Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.
T3S1117 Pseudoaspidin
T3S1149 Ganoderic acid G Ganoderic acid G is a highly oxidized lanostane-type triterpenoid from the fungus ganoderma lucidum.
T3S1196 mogroside IV Mogrosides IV is a sweet minor cucurbitane glycoside, it exhibits maltase inhibitory effect(IC50 : 10 mM), and with antioxidant, antidiabetic and anticancer activities.
T3S1251 Neoruscogenin 1. Neoruscogenin represents a universal pharmacological tool for RORα research due to its specific selectivity profile versus other nuclear receptors.
T3S1265 Liriopesides B Liriopesides B exhibited potential anticancer activity against human ovarian cancer A2780 cells.
T3S1319 Magnoflorine 1. Sinomeni Caulis et Rhizoma has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. 2. Magnoflorine and Sinomenine have p
T3S1320 Magnoflorine iodide Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
T3S1390 Leucoside Leucoside is a naturally occuring flavonol bioside with many biological activities.
T3S1447 Arteannuin B 1. Arteannuin B has potent antimalarial activity.
T3S1457 Palmatrubine Palmatrubine shows high antitumor activity.
T3S1513 (20R)-Protopanaxdiol 1. Protopanaxdiol has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity
T3S1541 rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m
T3S1589 NotoginsenosideFa 1. Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.
T3S1591 Notoginsenoside Fc 1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.
T3S1628 Vitexin -4''-O-glucoside Vitexin-4''-O-glucoside could effectively protect ECV-304 cells against cytotoxicity induced by TBHP through resuming mitochondrial function.
T3S1729 Dihydrolycorine 1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts prot
T3S1816 Parishin B 1. Parishin B can prevent vascular dementia.
T3S1852 Cephaeline hydrochloride NA
T3S1873 Talatisamine 1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+
T3S1888 Deltaline Use of Deltaline as versatile antidotes against poisoning of animals and humans.
T3S1892 Crassicauline A 1. Crassicauline A and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively.
T3S1896 Linderene 1. Linderene, linderalactone and isolinderalactone inhibit the enzymes from both origins to the same extent.
T3S1944 Darutoside 1. Darutoside can as an appropriate treatment for wounds. 2. Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decrea
T3S1955 7-Ethylcamptothecin 1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b). 7-Ethylcamptothe
T3S1967 Abrine Abrine exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse al
T3S2019 Lathyrol 1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance.
T3S2027 Rubusoside 1. Rubusoside is a natural sweetener . 2. Rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties.
T3S2105 N-Benzylpalmitamide N-benzylpalmitamide inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and
T3S2152 Anemosapogenin Anemosapogenin shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed.
T3S2197 Polygalic acid Triterpenoid saponin. Shows expectorant, emetic and stimulant effects. Orally active.
T3S2210 Lancerin
T3S2312 Poncirin 1. Poncirin shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis
T3S2340 Usaramine Usaramine demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
T3S2372 7-Epitaxol 1. 7-Epitaxol is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.
T3S2381 Perillen Perillen is an actiive constituent in the drug which promotes enterocinesia. Perillen demonstrates strong resistance activity against staphylococcus aureus and E.coli.
T3S2390 Caftaric acid 1. Caftaric acid has anti-mutagenicity. 2. Caftaric acid is an inhibitor of the protein-protein interactions mediated by the Src-family kinases.
T4005 FDI-6 FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
T4018 WST-8 WST-8 is a water-soluble tetrazolium dye, the sensitivity of the WST-8-based assay is higher than the conventional MTS-based assay.
T4020 Cadazolid Cadazolid is an oxazolidinone-type antibiotic, with activity against gram-positive bacteria, including Clostridium difficile.
T4023 L-Argininamide dihydrochloride L-Argininamide (L-Arm) is used as a model compound in studies of the physicochemical characteristic of ligand binding DNA aptamers and their potential development as fluorescent ap
T4025 HMN-154 HMN-154 is a novel benzenesulfonamide anticancer compound.
T4027 KIN1148 KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection following viral infection
T4035 Khasianine Khasianine has strong activity against liver damage induced by CCl4.
T4036 Solasodine Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer
T4038 Ectoine Ectoine is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as
T4040 AN2718 AN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro. It inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM f
T4054 Dantrolene sodium hemiheptahydrate Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine recepto
T4055 Etoxazole Etoxazole is an acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection.
T4056 Cyclizine hydrochloride Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.
T4057 Hoechst 33258 Hoechst 33258 is a benzimidazole anti-filarial agent. it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication. it also
T4059 Selamectin Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus l
T4061 LY2334737 LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T4066 FIN56 FIN56 is a specific inducer of ferroptosis.
T4070 Glycocholic Acid Sodium Salt Glycocholic Acid Sodium Salt is a conjugated bile salt and ionic biologic detergent. It is involved in the emulsification of fats.
T4072 Methyl-β-cyclodextrin Methyl-β-cyclodextrin, a cyclic heptasaccharide, is an effective agent for the depletion of cholesterol from cells; also inhibits PEL cell growth with an IC50 of 3.33-4.23 mM.
T4085 Chonglou Saponin VII Chonglou saponin VII shows inhibitory effects on cell proliferation.
T4086 Gly-Leu Gly-Leu is a substrate for the assay of glycyl-L-leucine dipeptidase.
T4090 PF-06282999 PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
T4093 Afobazole hydrochloride Fabomotizole HCl (CM346 HCl), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF,
T4100 AS-8351 AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming
T4103 (L)-Sodium lactate Sodium L-lactate is produced from pyruvate by the enzyme Lactate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. L-Lactic A
T4105 AFN-1252 AFN-1252(Debio 1452) is an effective inhibitor of enoyl-acyl carrier protein reductase (FabI). It (≤0.12 μg/ml) inhibits all clinical isolates of Staphylococcus aureus and Staph
T4110 Perivine Perivine may resolve the instability of the retinoblastoma-associated proteins (RbAp48) complex and thus be used in Alzheimer's disease therapy. Perivine, vobasine, coronaridine an
T4116 Ademetionine S-ADENOSYL-L-METHIONINE (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells
T4123 LYN-1604 <p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
T4129 Arachidonic acid Arachidonic acid is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal p
T4130 Complanatoside Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.
T4136 Lapachol Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila m
T4137 4,7-DIHYDROXYCOUMARIN 4,7-DIHYDROXYCOUMARIN is a bioactive natural compound.
T4138 UCPH-101 UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
T4139 D-Luciferin Potassium Salt D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP.
T4165 Delpazolid Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with t
T4168 Visomitin Visomitin is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).
T4169 Methylnitrosourea N-Nitroso-N-methylurea is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
T4172 1-Methoxy PMS 1-Methoxy PMS is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.
T4174 NSC 191412 NSC 191412 is an active compound.
T4175 Fluonilid Loflucarban (Fluonilid) is an antimycotic compoud.
T4177 U 19963 U 19963 is an active compound.
T4178 NSC 80538 NULL
T4180 Adipamidoxime Adipamidoxime is an active compound.
T4181 Cosan 528 Cosan-528 is a bioactive chemical.
T4184 NSC 409012 NSC 409012 is an active compound.
T4187 Gemcitabine monophosphate sodium salt hydrate Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
T4191 Multi-kinase inhibitor I Multi-kinase inhibitor I is a Multi-kinase inhibitor.
T4193 TD-198946 TD-198946, a potent chondrogenic agent, is a thienoindazole derivative.
T4196 NSC19005 NSC19005 is structurally related to Betahistine. NSC19005 is a dimer of Betahistine.
T4200 AHU377 calcium salt AHU-377 hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.AHU377 is a prodrug of LBQ657 (Item No. 19829),
T4204 6-ethyl-7-hydroxy-4-methylchromen-2-one NA
T4207 Protein degrader 1 hydrochloride Protein degrader 1 hydrochloride is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
T4208 Targocil Targocil is used as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptible S. aureus (MSSA) and methicillin-res
T4233 Cys-Gly L-Cysteinylglycine, is a biologically important compound since it is formed during the γ-glutamyl cycle. It is a L-cysteinyl peptide, that can be used in the studies of many pepti
T4238 Guanidoacetic acid Guanidinoacetic acid, a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Guanidinoacetic Acid is an important m
T4244 Methylophiopogonone A NA
T4248 T.cruzi Inhibitor (1350920-22-7(free base)) T.cruzi Inhibitor is a Trypanosoma cruzi inhibitor.
T4269 Buparvaquone Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone.
T4271 Diroximel Fumarete Diroximel fumarate, a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.
T4275 Fluanisone Fluanisone is a butyrophenone derivative with sedative properties. It is a typical antipsychotic and is used in the treatment of schizophrenia.
T4283 SRI-011381 SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T4286 Fmoc-Val-Ala-PAB Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-pac
T4287 Succinobucol Succinobucol is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the hea
T4289 Mc-Val-Ala-PAB Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).
T4292 Thiaproline Thiaproline has been used in peptide coupling reactions.
T4304 Azoramide Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
T4306 CCG-203971 CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also in
T4329 CP 376395 CP 376395 is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
T4333 Quinine dihydrochloride Quinine Dihydrochloride is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).
T4346 SPDB SPDB is a small fragment linked to DM4 conjugates. It conjugates to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.
T4373 Brassinin Brassinin (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.
T4384 Halofenozide Halofenozide is an ecdysteroid agonist and used as a pesticide.
T4394 Methyl Isoferulate This product is isolated and purified from the leaves of Phyllostachys heterocycla
T4399 ML239 ML239 is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.
T4402 (4-Chloro-thiazol-2-yl)acetic acid (4-Chloro-thiazol-2-yl)acetic acid is a chemical compound.
T4404 Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate is a chemical compound.
T4406 2,6-Dimethylbenzoquinone 2,6-Dimethoxybenzoquinone (2,6-DMBQ) is a benzoquinone, a chemical compound found in Rauvolfia vomitoria and in Tibouchina pulchra.,At physiological concentrations 2,6-Dimethoxy-p-
T4412 Roquinimex Roquinimex (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF
T4433 6-CFDA N-succinimidyl ester The succinimidyl ester group is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mammalia
T4434 Tirapazamine Tirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The com
T4436 RO1138452 RO1138452 is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma aden
T4445 Tolfenpyrad Tolfenpyrad is an effective insecticide[1], used against pests that are resistant to existing insecticides such as organophosphates and carbamates.[2]
T4447 S-(5'-Adenosyl)-L-methionine tosylate S-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [
T4452 BT-11 BT-11 is an orally available LANCL2 binding compound. It is used in the therapy of inflammatory bowel disease.
T4454 Traumatic Acid Traumatic Acid is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective ca
T4494 CLOZAPINE N-OXIDE Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration [1]. It is produced by the action o
T4497 Amifampridine Amifampridine is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action pote
T4502 BISMUTH SUBGALLATE Bismuth subgallate is an astringent and antiseptic and is applied to skin diseases such as eczema.
T4506 Gadopentetate dimeglumine Gadopentetate dimeglumine, an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-b
T4509 Inositol nicotinate Inositol nicotinate has the effect of lowering cholesterol and expanding peripheral blood vessels for hypercholesterolemia and atherosclerosis.
T4510 Polaprezinc Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
T4521 Edg-2 receptor inhibitor 1 Edg-2 receptor inhibitor 1 is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
T4524 SBC-110736 SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor
T4525 Citraconic acid Citraconic acid is a dicarboxylic acid consisting of maleic acid having a methyl substituent at the 2-position.
T4529 ASP-9521 ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
T4542 Clonixin Clonixin is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium
T4545 Propacetamol Hydrochloride Propacetamol is a prodrug of paracetamol (acetaminophen) with improved water solubility. Propacetamol is an analgesic drug delivered by IV when the oral application of NSAID is not
T4552 Fursultiamine Fursultiamine is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.
T4557 Amylmetacresol Amylmetacresol is used in the treatment of sore throat or ‘acute sore throat’, pharyngitis, tonsillitis and laryngitis. As well as in the treatment of influenza A and SARS-CoV.
T4559 Isocarboxazid Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depres
T4561 Tiaprofenic acid Tiaprofenic acid is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
T4565 Tafamidis Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM; Kd2: 27
T4570 Pipobroman Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemi
T4572 Desoximetasone Desoximetasone(Topicort) is a medication belonging to the family of medications known as topical corticosteroids; is used for the relief of various skin conditions, including rashe
T4574 AHU-377 AHU-377 is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.
T4579 Pentagastrin pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally,which can cause the secretion and synthesis of salivary proteins.
T4581 3-hydroxycephem
T4582 xanthanol Xanthydrol is an organic chemical compound. Xanthydrol is used to test the levels of urea in the bloodstream.
T4585 Ethylenebis(oxyethylenenitrilo)tetraacet Ethylene glycol bis(2-aminoethyl)tetraacetic acid is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino
T4586 beta, beta-dimethylacrylshikonin beta, beta-dimethylacrylshikonin has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.
T4587 Mirificin Puerarin has been investigated for the treatment of Alcohol Abuse.
T4588 Glycochenodeoxycholic Acid Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolit
T4589 9'''-MethyllithosperMate B
T4591 Dihydrokavain Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.
T4592 TOMATIDINE HYDROCHLORIDE A steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatidine
T4593 ISOPIMPINELLIN Antiviral, anti HIV.
T4595 YHO-13177 YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1
T4601 9-Methoxycanthin-6-one 9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1
T4603 PEO-IAA PEO-IAA is a novel potent auxin antagonist.
T4604 HC-056456 HC-056456 is a CatSper channel modulator.
T4607 CAY10465 CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
T4608 PDM2 PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
T4609 Exo1 Exo1 is a chemical inhibitor of the exocytic pathway
T4620 Siramesine Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.lysoso
T4624 PGD2-inhibitor PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d)
T4627 SPI--112Me
T4630 NSC 404988
T4631 NSC 4810
T4632 NSC 6038 NA
T4635 Ralinepag Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP
T4636 Protein kinase inhibitors 1 Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
T4638 Fer and FerT inhibitor Fer/FerT kinase inhibitor
T4640 Parimifasor Parimifasor is an immunomodulator, with anti-inflammatory activity.
T4642 Tenovin-2
T4647 M2I-1 M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can dist
T4659 ELN484228 ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.
T4660 6,7-dimethoxy-N-(4-nitrophenyl)quinazoli
T4661 PKG drug G1 PKG drug G1 targets C42 of PKG Iα. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
T4663 QX77 QX77 is a chaperone-mediated autophagy (CMA) activator.
T4664 ML297 ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML297 exhibits no effect on GIRK2,
T4665 BMS626529 BMS-626529 is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
T4674 SB 297006 SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 25
T4675 4-Carboxyisothiazole NA
T4678 Fmoc-Val-Cit-PAB Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).
T4679 WM-1119 WM-1119 is a highly potent, selective KAT6A/B inhibitor
T4685 INOSINIC ACID Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and
T4698 8-Fluoro-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one
T4701 Diclofop-methyl Diclofop-methyl is used as the active ingredient in many herbicides that are used to control weed growth in plants such as wheat and wild oats.
T4703 2-Aminoethylphosphonic acid Ciliatine belongs to the class of organic compounds known as organic phosphonic acids. Ciliatine has been primarily detected in urine. Ciliatine participates in a number of enzymat
T4704 L-Anserine nitrate salt L-Anserine Nitrate Salt is a dipeptide found in most animal tissues. In model systems it is a potent antioxidant and scavener of hydroxyl radicals. The compound inhibits nonenzymat
T4705 Aminoadipic acid Aminoadipic acid (2-aminoadipate) is a metabolite in the principal biochemical pathway of lysine. It is an intermediate in the metabolism (i.e. breakdown or degradation) of lysine
T4707 3-Hydroxyanthranilic acid 3-Hydroxyanthranilic acid, also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthrani
T4708 N-Acetyl-D-galactosamine Acetylgalactosamine is an important constituent of brain heteropolysaccharides (glycoproteins).
T4710 3-Methoxytyramine hydrochloride 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in huma
T4711 2,4-Dihydroxypyrimidine-5-carboxylic acid 2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synth
T4712 cis-4-Hydroxy-D-proline cis-4-Hydroxy-D-proline belongs to the class of organic compounds known as proline and derivatives. Proline and derivatives are compounds containing proline or a derivative thereof
T4713 Phosphocholine chloride calcium salt tet Phosphorylcholine is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the concentration of phosphorylcholine as the
T4714 Methyl indole-3-acetate Indole-3-methyl acetate is found in apple. It is isolated from immature seeds of beach pea (Lathyrus maritimus), Vicia amurensis, wild soybean (Glycine soja), lobiya (Vigna catiang
T4715 2'-Deoxyguanosine monohydrate Deoxyguanosine is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA
T4716 Pyrrole-2-carboxylic acid Pyrrole-2-carboxylic acid was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino
T4717 25-Hydroxycholesterol 25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also pla
T4718 Uridine 5'-monophosphate 5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Uridine 5'-monophosphate is a nucleotide that is f
T4719 D-Gulonic acid γ-lactone L-Gulonolactone (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC, which catalyzes the last step of the bio
T4721 β-Nicotinamide mononucleotide Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicoti
T4722 O-Acetyl-L-serine hydrochloride O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in huma
T4723 D-(-)-Tagatose D-Tagatose, a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods
T4725 N-Acetyl-D-mannosamine N-Acetylmannosamine is a monosaccharide that is used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. N-Acetyl-
T4726 D-Glucose 6-phosphate sodium salt In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase dur
T4727 Sodium taurolithocholate The major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
T4728 4-ACETAMIDOBUTYRIC ACID 4-Acetamidobutanoic acid can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to huma
T4729 Phosphonoacetic acid Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is pr
T4730 Thymidine 5'-monophosphate disodium salt Thymidine-5'-monophosphate (TMP) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chr
T4731 2'-Deoxycytidine 5'-monophosphate 2'-Deoxycytidine 5'-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC to form dCDP which upon phosphorylat
T4733 Sucrose Sucrose is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
T4734 Suberic acid Suberic acid is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dic
T4735 2'-Deoxyuridine 5'-monophosphate disodium salt 2'-Deoxyuridine 5'-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of
T4736 ML092 Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor (IC50: 10 nM).
T4737 2'-Deoxyadenosine 5'-monophosphate Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucl
T4738 SODIUM 2-HYDROXYBUTYRATE 2-Hydroxybutyric acid is formed as a by-product of the formation of alpha-ketobutyrate via a reaction catalyzed by lactate dehydrogenase (LDH) or alpha-hydroxybutyrate dehydrogenas
T4739 Creatine phosphate disodium salt tetrahydrate Creatine phosphate disodium salt tetrahydrate is a substrate for the assay of creatine kinase
T4740 Elaidic acid Elaidic acid is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated w
T4741 N-Formylglycine N-Formylglycine is a simple dipeptide and a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.
T4743 UDP-Glucose sodium salt UDP-Glucose sodium salt is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM). It can
T4744 5-HYDROXYINDOLE-3-ACETIC ACID 5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and le
T4746 Purine Purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines.
T4747 3-Methyl-2-buten-1-ol Prenol is found in blackcurrant. Prenol is a constituent of ylang-ylang and hop oils. Prenol is found in orange peel oil and various fruits e.g. orange, lemon, lime, grape, pineapp
T4748 Glycolaldehyde dimer Glycoaldehyde Dimer is derivative of glycolaldehyde, which is the precursor molecule of various significant compounds including amino acid glycine and in the formose reaction.
T4749 Squalene Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran,
T4751 (2R,3R)-(-)-2,3-Butanediol (2R,3R)-2,3-Butanediol is found in cocoa and cocoa products. (2R,3R)-2,3-Butanediol is isolated from cocoa butter and roots of Ruta graveolens (rue).2,3-Butanediol is one of the co
T4754 Pyridoxamine dihydrochloride Pyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.
T4755 DL-2,3-Diaminopropionic acid monohydroch L-Tryptophanamide Hydrochloride is an amino acid amide used as a substrate for studying the action of aminopeptidase enzyme.
T4757 L-Homoserine Homoserine is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer to
T4758 2'-Deoxycytidine monohydrate One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phospha
T4759 Urocanic acid Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation.
T4760 3-Hydroxybenzyl alcohol 3-Hydroxybenzyl alcohol (CAS Number 620-24-6) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or beige to brown crystal
T4761 Pyridoxal hydrochloride The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine),
T4762 L-Pipecolic acid L-Pipecolic acid is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adreno
T4764 mono-Methyl glutarate Monomethyl glutaric acid is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae in vitro demonstrated that hydrolysis of DBEs yields mainly the monometh
T4765 L-Norleucine L-Norleucine is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
T4766 3-Methylglutaric acid Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PM
T4767 Formamide Formamide is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been expo
T4768 Diethyl oxalpropionate Diethyl oxalpropionate, also known as methyloxalacetic acid diethyl ester or diethyl methyloxalacetate, is a member of the class of compounds known as beta-keto acids and derivativ
T4772 DL-Leucine (+/-)-Leucine or DL-Leucine can be found in Green bell peppers, Green zucchinis, Italian sweet red peppers, and Red bell peppers.
T4773 Monoethyl malonic acid Monoethyl malonic acid belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid gro
T4775 Arachidic acid Arachidic acid is a saturated fatty acid found naturally in fish and vegetable oils (such as those from peanuts). It can also be formed by the hydrogenation of arachidonic acid. Di
T4776 Glycerol Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and
T4779 4-Methylcatechol 4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-methylcatechol is known to induce the pro
T4780 Quinaldic acid Quinaldic acid, also known as quinaldate or chinaldinsaeure, belongs to the class of organic compounds known as quinoline carboxylic acids.
T4781 N-Acetyl-L-phenylalanine N-Acetyl-L-phenylalanine is an essential amino acid produced for medical, feed, and nutritional applications. It appears in large amount in urine of patients with phenylketonuria w
T4784 (S)-(-)-1-Phenylethanol 1-Phenylethanol exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). 1-Phenylethanol has been detected in multiple biofluids, such as feces
T4786 D-(-)-Ribose D-Ribose, commonly referred to as simply ribose, is a five-carbon sugar found in all living cells. Ribose is not an essential nutrient because it can be synthesized by almost every
T4787 α-Hydroxyisobutyric acid Alpha-Hydroxyisobutyric acid is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be obtained through environmental exposure. MTBE is rapidly eliminated from the body, mainl
T4788 L-Norvaline Norvaline is a non-proteinogenic branched-chain amino acid. It has previously been reported to be a natural component of an antifungal peptide of Bacillus subtilis. Norvaline and o
T4794 Glutaric acid Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryp
T4795 Pimelic acid Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine. Pimelic acid is one methylene longer than a related dicarboxylic acid, adipic acid, a
T4797 Bis(2-ethylhexyl) phthalate Bis(2-ethylhexyl) Phthalate plasticizer is used to impart softness and flexibility to PVC products. Bis(2-ethylhexyl) Phthalate has been implicated in obesity and insulin resistanc
T4798 N-Acetyl-L-leucine N-Acetylleucine belongs to the class of organic compounds known as leucine and derivatives. Leucine and derivatives are compounds containing leucine or a derivative thereof resulti
T4799 Indole Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole rin
T4801 2,5-Dimethylpyrazine 2,5-Dimethylpyrazine is present in asparagus, wheat bread, crispbread, Swiss cheeses, black or green tea, soya, malt, raw shrimp and squid. 2,5-Dimethylpyrazine is used as flavor a
T4804 Pyruvic acid Pyruvic acid is an intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues
T4805 2-Hydroxypyridine 2-Hydroxypyridine is the catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.
T4806 D-Tryptophan Tryptophan is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the marine venom peptide).
T4807 Potassium sorbate Potassium Sorbate acts as a potential antifungal agent when used in conjunction with polyethylene films. It also used as a corrosion inhibitor via corrosion mitigation.
T4808 Agmatine sulfate salt Agmatine sulfate is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and
T4809 Pyrimidine Pyrimidines are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleoside
T4810 2,3-Dihydroxybenzoic acid Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma and has increased levels after aspirin ingestion.
T4812 D-Mannose D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylation of specific proteins.
T4813 L-Citrulline L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
T4814 D-Pyroglutamic acid D-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex a
T4815 Hippuric acid Hippuric acid is an acyl glycine formed by the conjugation of benzoic acid with glycine. Hippuric acid is a normal component of urine and is typically increased with increased cons
T4816 6-Hydroxypyridine-3-carboxylic acid 6-hydroxynicotinic acid (6-OHNA) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract i
T4817 Methylmalonic acid Methylmalonate (MMA) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A. It is an indicator of Vitamin B-12 deficiency in cancer.
T4818 2-Deoxy-D-ribose 2-Deoxy-D-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
T4819 Pipecolinic acid Pipecolic acid is a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF.
T4822 N-Acetylglycine N-Acetylglycine is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.
T4823 D-(-)-Fructose Fructose-1P, also known as D-(-)-Fructose or D-(-)-Levulose, is classified as a member of the Monosaccharides.
T4824 5,6-Dimethylbenzimidazole Dimethylbenzimidazole is an intermediate in Riboflavin metabolism. Dimethylbenzimidazole is the second to last step for the synthesis of alpha-Ribazole. It is converted from Ribofl
T4825 D(+)-Xylose Xylose or wood sugar is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucr
T4826 L-Histidine monohydrochloride monohydrat Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a ch
T4827 Trimethylamine hydrochloride Trimethylamine is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagina i
T4828 D-(-)-Pantolactone Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety, which consists of
T4829 3-Hydroxyphenylacetic acid 3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxyg
T4831 2-Aminoisobutyric acid Aminoisobutyric acid is a nonprotein amino acid (is an end product of pyrimidine metabolism) excreted in the urine of about 5% of healthy individuals, and high excretion is an auto
T4832 Cytosine Cytosine is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucle
T4833 N-Acetyl-DL-tryptophan N-Acetyl-tryptophan was study for its possible anti-inflammatory and antinociceptive activities from the extraction of a Turkish plant, Salsola grandis.
T4834 Indole-3-acetamide 1H-Indole-3-acetamide, also known as auxin amide or 2-(3-indolyl)acetamide, belongs to the class of organic compounds known as 3-alkylindoles. Within the cell, 1H-indole-3-acetamid
T4837 Itaconic acid Itaconic acid, also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid ex
T4838 L-(-)-Malic acid Malic acid is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple.
T4839 N-Acetyl-L-alanine N-Acetyl-L-alanine is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4
T4840 3-Hydroxybenzoic acid Produced in the gut microflora as one of the three main metabolites formed from the catechin diet. Its use in the production of glycol benzoates for the application of plasticizer
T4843 Glyoxylic acid monohydrate Glyoxylic acid or oxoacetic acid is an organic compound that is both an aldehyde and a carboxylic acid.It is an intermediate of the glyoxylate cycle, which enables certain organism
T4844 L-Methionine L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
T4845 L-Lactic acid Lactic acid is an organic acid. It is a chiral molecule, consisting of two optical isomers, L-lactic acid and D-lactic acid, with the L-isomer being the most common in living organ
T4848 DL-Mandelic acid It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabo
T4850 2-Picolinic acid PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
T4851 Methyl acetoacetate Methylacetoacetic acid has been identified in the urine of patients with an inherited deficiency of propionyl-CoA carboxylase, and after isoleucine loading in the diagnosis of 2-me
T4852 Glyceryl trimyristate Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast
T4853 1-Methylnicotinamide chloride Niacin metabolite excreted via the urinary system.
T4854 Lithium acetoacetate Acetoacetic acid (AcAc) is a weak organic acid that can be produced in the human liver under certain conditions of poor metabolism leading to excessive fatty acid breakdown (diabet
T4855 Tricosanoic acid Tricosylic acid, also known as N-tricosanoate or tricosylate, belongs to the class of organic compounds known as very long-chain fatty acids.Tricosylic acid has been detected in mu
T4856 Nα-Acetyl-L-lysine N-Alpha-acetyllysine is a N-acetylated amino acid. It is a normal constituent of human urine with concentrations in normal samples too small to allow its routine detection; however
T4857 Lumazine Lumazine is a new MALDI matrix for complex (phospho)lipid mixtures analysis.
T4858 4-Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the e
T4859 rac-Glycerol 1-myristate 1-Myristoyl-rac-glycerol, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains. 1-Myristoyl-rac-glycerol is used in colloi
T4860 Serotonin creatinine sulfate monohydrate Serotonin creatinine sulfate complex is a neurotransmitter.
T4861 trans-Aconitic acid Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic
T4862 Oxaloacetic acid Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate
T4863 DL-Homocysteine DL-Homocysteine is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.
T4864 Methyl-β-D-galactopyranoside Methyl beta-D-glucopyranoside, also known as alpha-methyl-D -mannoside or beta -D-glucopyranoside, methyl. Within the cell, methyl beta-D-glucopyranoside is primarily located in th
T4866 L-Tryptophanamide hydrochloride Tryptophanamide belongs to the class of organic compounds known as tryptamines and derivatives. Tryptophanamide has been detected in multiple biofluids, such as urine and blood.
T4867 Erucic acid Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid is broken
T4868 gamma-Linolenic acid γ-Linolenic acid, is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic A
T4869 D-(+)-ALLOSE D-Allose is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refrac
T4870 Petroselinic acid Petroselinic acid is a monounsaturated omega-12 fatty acid found naturally in plant and animal oils and fats.
T4871 D-Glucosaminic acid D-Glucosaminic Acid is a useful starting material for the synthesis of aldonic acids.
T4872 Palmitoleic acid Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.
T4873 2-Amino-1-phenylethanol 2-Hydroxyphenethylamine has been found in human testicle tissue, and has also been primarily detected in blood. 2-Hydroxyphenethylamine can be converted into 2-(hydroxymethyl)-4-(1
T4874 Thiamine pyrophosphate Thiamine pyrophosphate is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biolo
T4875 6-O-α-D-Glucopyranosyl-D-fructose, Isoma Palatinose is a disaccharide having an α(1→6) linkage between D-glucose and D-fructose and is similar to sucrose in its physicochemical properties. It is produced from sucrose i
T4876 Tryptophol Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.
T4877 L-Homocystine Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Incre
T4879 12-Hydroxydodecanoic acid 12-hydroxydodecanoic acid is the substrate of the human glutathione-dependent formaldehyde dehydrogenase.
T4880 L-Dihydroorotic acid L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the ce
T4881 O-Phosphorylethanolamine Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown. Phosp
T4882 DL-Arabinose D-Arabinose, also known as (+/-)-arabinose or aloe sugar, belongs to the class of organic compounds known as pentoses. D-Arabinose has been primarily detected in feces. Within the
T4883 Creatine Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the
T4884 α-D-Glucose Alpha-D-Glucose is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therape
T4886 Dihydrouracil 5,6-Dihydrouracil is an intermediate breakdown product of uracil.
T4887 DL-3-AMINOISOBUTYRIC ACID beta-aminoisobutyric acid is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC, the last step in pyrimidine d
T4888 Phosphocreatine disodium salt hydrate Phosphocreatine disodium salt hydrate ishigh-energy phosphate reservoir in vertebrate and some invertebrate muscle; provides phosphate for ADP-ATP conversion
T4889 2,6-Diaminoheptanedioic acid Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram
T4890 3-Nitro-L-tyrosine 3-Nitrotyrosine is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitri
T4891 Sodium phenylpyruvate Phenylpyruvic acid is a substrate for phenylpyruvate decarboxylase and phenylpyruvate tautomerase.
T4892 3-(2-Hydroxyphenyl)propionic acid 3-(2-Hydroxyphenyl)propanoic acid, also known as melilotic acid or melilotate. Within the cell, 3-(2-hydroxyphenyl)propanoic acid is primarily located in the cytoplasm. 3-(2-Hydrox
T4893 Spermidine Spermidine inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4)
T4894 L-(-)-Arabitol L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose
T4895 Cadaverine dihydrochloride Cadaverine dihydrochloride, dihydrochloride salt of cadaverine (a diamine), is a biogenic amine
T4896 D-(-)-Lyxose D-(-)-Lyxose is used as a chiral building block.
T4897 Inosine 5'-triphosphate trisodium salt InInosine 5'-triphosphate trisodium salt is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to
T4898 Phospho(enol)pyruvic acid monopotassium Phosphoenolpyruvic acid, monopotassium salt is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is
T4899 L-Histidinol dihydrochloride L-Histidinol dihydrochloride is a precursor of histamine and a reversible inhibitor of protein synthesis.
T4900 (±)-Methyl Jasmonate (±)-Jasmonic acid methyl ester induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. More specificall
T4901 Guanosine 5'-monophosphate disodium salt Guanosine monophosphate, also known as guanylic acid or 5'-GMP, belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic a
T4902 ISOQUERCITRIN Isoquercitrin is an effective antioxidant and an eosinophilic inflammation suppressor.
T4903 Heptadecanoic acid Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat)
T4904 1-Methylguanidine hydrochloride Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates i
T4906 D-(-)-Tartaric acid D-Tartaric acid, also known as (S,S)-tartarate or D-threaric acid, belongs to the class of organic compounds known as sugar acids and derivatives. Within the cell, D-tartaric acid
T4907 3,4-Dihydroxyphenylacetic acid 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.
T4909 N-Acetyl-DL-methionine N-acetyl-L-methionine is nutritionally and metabolically equivalent to L-methionine. Methionine is a dietary indispensable amino acid required for normal growth and development of
T4911 alpha-Arbutin Alpha-arbutin is a synthetic and functional active ingredient for skin lightening.
T4914 Sodium mesoxalate monohydrate Mesoxalic acid is primarily located in the cytoplasm within the cell. Mesoxalic acid can be biosynthesized from malonic acid. Outside of the human body, mesoxalic acid can be found
T4915 β-Glycerophosphate disodium salt hydrate β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibito
T4916 D-Saccharic acid potassium salt D-Saccharic acid potassium salt is a compound formed from oxidizing sugars, which can be used to test for the presence of hepatic enzyme induction. Studies indicate that D-glucuron
T4917 (L)-Dehydroascorbic acid L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotect
T4919 3-Ureidopropionic acid Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. I
T4920 α-Ketoglutaric acid sodium salt alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of
T4921 Oxoadipic acid Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research o
T4922 Uridine 5′-triphosphate tris salt Uridine 5'-triphosphate tris salt is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca2+, as well as a phosphate donor for in vitro kinas
T4923 7-Dehydrocholesterol 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
T4924 α-D-Glucose 1-phosphate disodium salt hy α-D-Glucose 1-phosphate disodium salt is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.
T4925 Thiamine monophosphate chloride dihydrat Thiamine monophosphate chloride dihydrat is a compound used in the screening of ligands that promote protein stability
T4926 Melanin Melanin from Sepia officinalis consists of polymers of tyrosine derivatives causing darkness in skin.
T4927 4-Guanidinobutyric acid 4-Guanidinobutyric acid is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid
T4928 L-Kynurenine L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor im
T4929 L-2-Phosphoglyceric acid disodium salt h 2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penul
T4930 ISOBUTYRALDEHYDE OXIME 2-methylpropanal oxime is an aldoxime derived from 2-methylpropanal. It derives from an isobutyraldehyde.
T4931 Dihydroxyfumaric acid hydrate Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously
T4933 Nα-Acetyl-L-asparagine N-Acetylasparagine, also known as acasn, belongs to the class of organic compounds known as asparagine and derivatives.
T4934 1-Methyl-L-histidine Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
T4937 DL-5-Hydroxylysine hydrochloride DL-5-Hydroxylysine is a racemic mixture of D- and L- enantiomers of 5-hydroxylysine which may be used as potential target markers for radical-induced protein oxidation.
T4939 Indole-3-pyruvic acid Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environm
T4940 3-Methylhistamine dihydrochloride N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histam
T4941 D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT Fructose 6-phosphate is an important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step of the Embden-M
T4942 α-D-Galactose-1-phosphate Dipotassium Pentahydrate Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars metabolism pathways.
T4943 1-Oleoyl-rac-glycerol 1-O-Oleyl-rac-glycerol, also known as monoolein, is a surfactant that releases free glycerol and oleic acid upon hydrolysis. Monoolein has been used in liquid crystal studies and r
T4944 Nervonic acid Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enha
T4945 DL-Normetanephrine hydrochloride rac-Normetanephrine Hydrochloride is a metabolite of Epinephrine. It is found together with Metanephrine in urine and in certain tissues.
T4946 COLUMBIANETIN ACETATE Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of columbianetin acetate is a passive diffusion process without pH-depe
T4947 3-Hydroxybutyric acid 3-Hydroxybutyric acid (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised
T4948 (±)-Potassium citramalate monohydrate Citramalic acid is an analog of malic acid. It can inhibit the production of malic acid.
T4949 1,2-Didecanoyl-sn-glycero-3-phosphocholi 1,2-Didecanoyl-sn-glycero-3-phosphocholi is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones s
T4950 1,2-Dipalmitoyl-sn-glycerol 1,2-Dipalmitoyl-sn-glycerol is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.
T4951 kauran-16,17-diol
T4956 tetrahydroxyl diphenylethylene-2-o-gluco EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like ce
T4959 Mannitol Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake
T4961 9'-Methyl lithospermate B
T4964 steviolbioside Steviolbioside is a natural sweetener, it presents notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC
T4968 KHS 101 KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
T4969 Guanosine 5'-triphosphate trisodium salt Guanosine 5'-triphosphate trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and
T4970 LANOSTEROL Lanosterol is a tetracyclic triterpenoid which is the compound from which all steroids are derived.
T4971 5'-DEOXYADENOSINE 5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genet
T4972 2'-Deoxycytidine-5'-diphosphate trisodiu 2′-Deoxycytidine 5′-diphosphate (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase ( for the production of dCTP to support DNA biosynthesis and revers
T4973 1,7-DIMETHYLXANTHINE Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Para
T4983 Isoetharine mesylate salt Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. it also is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression.
T4987 Calcium α-D-heptagluconate hydrate Calcium glucoheptonate is the calcium salt of (2xi)-D-gluco-heptonic acid. It is used as a calcium supplement for treatment of hypocalcemia.
T4989 Fosfomycin Tromethamine An antibiotic produced by Streptomyces fradiae.
T4991 Ertapenem sodium Ertapenem sodium is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with exten
T4994 Tocofersolan Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due t
T4996 Atosiban Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhi
T4A2458 Resibufogenin 1. Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I
T4A2462 Telocinobufagin 1. Telocinobufagin is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of F
T4P2931 Linoleic acid Essential fatty acid. Prostaglandin precursor.
T4S0039 Quercetin-3-O-sophoroside 1. Quercetin-3-O-sophoroside is the natural ligand of Bet v 1.
T4S0051 Coptisine sulfate 1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
T4S0083 Protostemonine 1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the
T4S0111 Hupehenine Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic receptors and chol
T4S0171 Crocetin 1. Croceic acid is a singlet oxygen quencher.
T4S0176 Alnustone Alnustone exerts significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.
T4S0350 Licochalcone B 1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer
T4S0528 Rhodojaponin V Antibacterial; anti-inflammatory.
T4S0536 Bullatine A 1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treatment of neurodegene
T4S0537 Bullatine B Bullatine B shows analgesic/anti-inflammatory properties.
T4S0554 Theaflavine-3,3'-digallate 1. Theaflavine-3,3'-digallate and lactic acid together could reduce herpes simplex virus transmission.
T4S0592 Toddalolactone anti-inflammatory and analgesic.
T4S0647 Butylphthalide Butylphthalide is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.
T4S0675 Polygalasaponin V Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxioly
T4S0758 Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden is a flavonoid from Quercetin.
T4S0790 Diosbulbin B 1. Diosbulbin B exhibits potential hepatotoxicity. 2. Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time.
T4S0794 (R)-(+)-Corypalmine 1. (R)-(+)-Corypalmine shows strong papaverine-like activity.
T4S0931 Pseudolaric acid A 1. Pseudolaric acid A and -B can inhibit the growth of particular cell type.
T4S1024 Picfeltarraenin IB 1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.
T4S1102 Liensinine diperchlorate
T4S1173 Agrimol B 1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.
T4S1312 Methyl gypsogenin 3-O-beta-D-glucuronopy 1. Gypsogenin 3-O-beta-D-glucuronopyranoside shows inhibitory activity toward pancreatic lipase with IC5 value of .29 mM, and the free carboxylic acid groups in position 28 within
T4S1321 Magnoflorine chloride 1. Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
T4S1422 Praeruptorin E 1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs
T4S1469 Cucurbitacin IIb 1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis.
T4S1499 Ginsenoside Rk1 Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat
T4S1519 Pseudoginsenoside RT5 1. Pseudoginsenoside RT5 has anti-epilepsy,anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor
T4S1578 Nystose Nystose is a tetrasaccharide with two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose.
T4S1637 gamma-Mangostin 1. Gamma-Mangostin as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 c
T4S1659 Xanthotoxol Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
T4S1796 Heterophyllin B Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression
T4S1820 Parishin A Parishin A is isolated from the rhizomes of Gastrodia elata. It has good neuroprotective effects against brain disorders.
T4S1848 Tubeimoside II Tubeimoside II(Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.
T4S1869 12-Epinapelline 12-Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ c
T4S1876 3-Deoxyaconitine 3-Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action po
T4S1881 Aconine 1. Aconine is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
T4S1943 Kirenol 1. Kirenol has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor
T4S1980 Maoecrystal A
T4S1983 Periplogenin 1. Periplogenin plays protective roles against thyrotoxicosis and associated cardiovascular problems, are mediated through its direct antithyroidal and/or LPO inhibiting propertie
T4S1990 Carvacrol 1. 5-Isopropyl-2-methylphenol presents anxiolytic effects. 2. 5-Isopropyl-2-methylphenol presents antinociceptive activity. 3. 5-Isopropyl-2-methylphenol presents antidepressant
T4S2014 5,15-Diacetyl-3-benzoyllathyrol 1. 5,15-Diacetyl-3-benzoyllathyrol is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excel
T4S21320 ISOGINKGETIN 1. Isoginkgetin, a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of ad
T4S2164 Narirutin 1. Narirutin has antiproliferative property. 2. Narirutin has anti-oxidant property. 3. Narirutin has anti-allergic and anti-inflammatory properties , can reduce airway inflammatio
T5000 Diflucortolone valerate Diflucortolone valerate is a corticosteroid esterified with valeric acid. It helps to reduce itching, redness, and swelling.
T5002 Methyl Aminolevulinate Hydrochloride Methyl Aminolevulinate Hydrochloride is commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.
T5004 Sodium Hyaluronate Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in
T5005 Eperisone hydrochloride Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.
T5007 Benproperine phosphate Benproperine phosphate is a cough suppressant.
T5013 Brequinar Brequinar is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.
T5014 Prostaglandin E2 (PGE2) Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constricti
T5015 Gonadorelin Acetate Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
T5017 Nimustine Hydrochloride Nimustine has been used in trials studying the treatment of Glioblastoma.
T5020 Eptifibatide Eptifibatide, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.
T5023 Propiverine hydrochloride Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).
T5024 Cefotiam Hexetil Hydrochloride Cefotiam Hydrochloride is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam
T5026 Oxytocin (Syntocinon) Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
T5032 Iguratimod Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migratio
T5039 Sodium 4-aminohippurate Hydrate The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
T5040 Medroxyprogesterone Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.
T5046 Haloxyfop (±)-Haloxyfop is a herbicide.
T5052 Ponazuril Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.
T5055 N-Formyl-L-methionine Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formyl methionyl tRNA. This process occurs in Escherichia coli and othe
T5057 O-PHOSPHO-L-SERINE DL-O-Phosphoserine, a normal metabolite in human biofluid, is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by
T5060 2-Oxobutyric acid 2-Ketobutyric acid is a product of the lysis of cystathionine. It is also one of the degradation products of threonine. It can be converted into propionyl-CoA, and thus enter the c
T5061 Lumichrome Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrat
T5063 4-Methyl-2-oxopentanoic acid 2-Methylglutaric acid is an organic acid normally found in human urine, in healthy adults and children. It is a metabolite of succinic acid, a citric acid cycle intermediate.
T5064 Oxalic acid dihydrate Oxalic acid is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolize
T5066 Lys(Me)3-OH Chloride Nε,Nε,Nε-Trimethyl-L-lysine is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxi
T5067 Flavin Adenine Dinucleotide Disodium FAD is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that facilitates the tran
T5068 D(+)-Glucuronic acid sodium salt monohydrate Glucuronic acid is a carboxylic acid and highly soluble in water. In humans, glucuronic acid is often linked to toxic or poisonous substances to allow for subsequent elimination, a
T5069 D-Glucose 6-phosphate potassium salt In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase dur
T5071 4-Methyl-2-oxovaleric acid 4-Methyl-2-oxopentanoic acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. It is both a neurotoxin and a metabotoxin.
T5072 Glycocholic acid hydrate Glycocholic Acid is the product of conjugation of cholic acid with glycine. It is the chief ingredient of the bile of herbivorous animals.
T5073 Disodium 5'-inosinate monohydrate Inosine monophosphate, or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.
T5074 Cholesteryl palmitate Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in
T5075 Phytic acid dipotassium salt Phytic acid exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. It can be
T5076 L-allo-Threonine Threonine is an essential amino acid in humans. It is abundant in human plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lamenes
T5078 Orotic Acid Monohydrate Orotic acid is an intermediate product in pyrimidine metabolism.
T5079 Adenosine-5'-diphosphate trisodium salt Adenosine 5'-diphosphate sodium salt is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for
T5082 calcium hydroxymethionine Calcium hydroxymethionine, also known as 2-Hydroxy-4-(methylthio)butanoic acid calcium salt, is a nutrition enhancer. It exists as a solid, soluble (in water), and a weakly acidic
T5084 Xanthosine dihydrate Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed fr
T5085 Pyridoxal 5'-phosphate hydrate Pyridoxal 5′-phosphate, the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase
T5086 D-Lactose monohydrate Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osmotic regulator of l
T5087 Isocitric acid trisodium salt DL-Isocitric acid trisodium salt is the protonated form of isocitrate, a substrate in the citric acid cycle. It is useful as a marker for determining the composition of isocitrates
T5089 5-Aminovaleric acid 5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is forme
T5090 2-Methylbutyraldehyde 2-Methylbutanal belongs to the class of organic compounds known as short-chain aldehydes.
T5095 Oxazolone Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression
T5098 Isochlorogenic acid A 3,5-Dicaffeoylquinic acid is a natural phenolic acid with antioxidant and anti-inflammatory activities .
T5102 TGN020 TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
T5103 AKOS B018304 AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
T5113 L-GLUCOSE L-Glucose is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.
T5121 TD139 TD139 is an inhaled galectin-3 inhibitor (Kd: 14 nM).
T5123 Pirozadil Pirozadil is a hypolipidemic agent.
T5129 SRI-011381 hydrochloride [1629138-41-5(free base)] SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T5141 L-2-Phosphoglyceric acid disodium salt hydrate 2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penul
T5145 Oxytocin acetate Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
T5146 Eptifibatide acetate Eptifibatide, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.
T5147 Polygalaxanthone XI NA
T5148 Atosiban acetate Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhi
T5149 MC-Val-it-PAB MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
T5154 C-176 C-176 is a highly potent and covalent mouse STING inhibitor.
T5161 Gadodiamide Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.
T5165 Deacetyltaxol Deacetyltaxol is extracted from Taxus brevifolia barks.
T5169 SGC-GAK-1 SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).
T5170 KHS101 hydrochloride KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.
T5173 SBI-0640756 SBI-0640756 (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.
T5182 AMZ30 AMZ30 is a selective inhibitor of PME-1 (IC50: 600 nM). It also reduces the demethylated form of PP2A in living cells.
T5185 PZ-2891 PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator(hPANK3,IC50:1.3 nM).
T5191 PF-9366 PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
T5196 DIM-C-pPhCO2Me DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.
T5206 DAAO inhibitor-1 DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).
T5212 Glycerol trilinoleate Glyceryl trilinoleate is a very common fatty acid and is useful in studies concerning the effects of fatty acids on lipid and cholesterol handling in organisms and for studies inve
T5213 Lithium potassium acetyl phosphate Acetyl phosphate is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. It is generated from sulfoacetaldehyde, converted to acetyl-CoA and ac
T5214 Cholesteryl linoleate Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-L
T5216 L-Threonic acid Calcium Salt Threonic acid is probably derived from glycated proteins or from the degradation of ascorbic acid. It is a normal component is aqeous humour and blood. Threonic acid is a substrate
T5217 Phenyl-ac-Gly-OH Phenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs, rats,
T5218 DL-Threitol D-threitol is the D-enantiomer of threitol. It has a role as a human metabolite. It is an enantiomer of a L-threitol.
T5219 L-allo-Isoleucine L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produc
T5220 Sodium D-lactate Lactic acid is an organic acid. It is a chiral molecule, consisting of two optical isomers, L-lactic acid and D-lactic acid, with the L-isomer being the most common in living organ
T5221 2-Hydroxy Hippuric Acid 2-Hydroxy Hippuric Acid (Salicyluric acid) is a metabolite of Salicylic Acid.
T5222 N-(5-Aminopentyl)acetamide N-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large dos
T5223 Heneicosanoic acid Heneicosanoic acid (HEA) is a fatty acid found in human milk fat. HEA is also a part of the phospholipids of the articular cartilage boundary lubricant. HEA is a constituent of red
T5224 2-Hydroxycaproic acid 2-Hydroxycaproic acid is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hydroxycaproic acid is
T5226 2-Methylhippuric acid Methylhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be us
T5227 Glycerol Tridecanoate Glycerol Tridecanoate is also known as triacylglycerols or triacylglycerides. The triglycerides are rebuilt in the blood from their fragments and become constituents of lipoprotein
T5228 Nicotinuric acid Nicotinuric acid is an acyl glycine which is normally minor metabolites of fatty acids. Acyl glycines are produced through the action of glycine N-acyltransferase.
T5230 DL-Indole-3-lactic acid DL-Indole-3-lactic acid is a reactant for the preparation of antibacterial agents.
T5231 2-Methylsuccinic acid Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measura
T5232 3-Methyl-2-oxobutanoic acid alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin, an acidogen,
T5233 N'-Methylnicotinamide N-methylnicotinamide is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-methylnicotinamide indicates nia
T5234 Glycoursodeoxycholic acid Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the
T5236 1-Methyl-hydantoin 1-Methylhydantoin is a small molecular weight polar substance, the product of degradation of creatinine by bacteria. In mammals, the metabolism of 1-methylhydantoin occurs via 5-hy
T5237 Hexadecanedioic acid Hexadecanedioic acid is activated by mitochondrial and microsomal fractions in the liver. It has antitumor activity.
T5238 1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies foc
T5240 Cholestenone 4-Cholesten-3-one is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals.
T5242 Glycerol Trieicosanoate TG(20:0/20:0/20:0) is a triarachidic acid triglyceride. Triglycerides (TGs) are also known as triacylglycerols or triacylglycerides. TGs are the main constituent of vegetable oil a
T5243 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine PE(14:0/14:0) is a phosphatidylethanolamine (PE or GPEtn). It is a glycerophospholipid in which a phosphorylethanolamine moiety occupies a glycerol substitution site. PE(14:0/14:0)
T5244 Aminomalonic acid Aminomalonic acid (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. T
T5245 N-Isovalerylglycine Isovalerylglycine (IVG) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inb
T5246 trans-2-Butene-1,4-dicarboxylic Acid 3-Hexenedioic acid is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disord
T5247 Trimethylamine N-oxide dihydrate Trimethylamine N-oxide (TMAO) is an oxidation product of trimethylamine and a common metabolite in animals and humans. In particular, trimethylamine-N-oxide is biosynthesized endog
T5248 (R)-3-Hydroxybutanoic acid 3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are rai
T5249 1,2-Distearoyl-sn-glycero-3-phosphoethan 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats, coco butter, and sesame oil.
T5250 1,6-anhydro-b-D-Glucose 1,6-anhydro-b-D-Glucose (Levoglucosan) is an anhydrohexose that is the 1,6-anhydro-derivative of beta-D-glucopyranose. It is formed from the pyrolysis of carbohydrates, such as sta
T5251 2-Oxo-3-phenylpropanoic acid Phenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally
T5252 1,11-Undecanedicarboxylic acid Undecanedicarboxylic acid is an unusual odd-numbered dicarboxylic acid that appears in the urines of children with neonatal adrenoleukodystrophy and Zellweger syndrome, as an addit
T5253 3-Methyladipic acid 3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so th
T5254 Glycodeoxycholic acid sodium salt Glycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes e
T5255 5-(Hydroxymethyl)uracil 5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hyd
T5256 All trans-Retinal Retinal is a carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein o
T5257 L-Homocitrulline Homocitrulline is a metabolite that can be detected in larger amounts in the urine of individuals with urea cycle disorders. The accumulation of carbamyl phosphate due to a deplete
T5259 Glycochenodeoxycholic acid sodium salt Glycochenodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of th
T5260 2-Methylglutaric acid 2-Methylglutaric acid is an organic acid normally found in human urine, in healthy adults and children. 2-Methylglutaric acid is a metabolite of succinic acid, a citric acid cycle
T5261 2-Octenoic acid 2-Octenoic acid is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma.
T5262 trans-3-Indoleacrylic acid trans-3-Indoleacrylic acid is a Tryptophan metabolite.
T5263 4-Hydroxymandelic acid p-Hydroxymandelic acid is an acidic metabolite of p-octopamine and p-synephrine (p-phenylephrine). It is also a naturally occurring metabolite of tyramine.
T5265 Phenyl-Ac-Gln-OH Phenylacetylglutamine is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound. Phenylacetylglutam
T5266 Glycerol Tri-n-octanoate Glycerol Tri-n-octanoate belongs to the family of triradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is e
T5267 N-Acetylglutamic acid N-Acetyl-L-glutamic acid (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu a
T5268 D-Arabitol D-Arabitol is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-pro
T5269 N-Acetyl-L-ornithine N-Acetylornithine is a minor component of deproteinized blood plasma of human blood. Human blood plasma contains a variable amount of acetylornithine, averaging 1.1 +/- 0.4 μmol/L
T5270 5-Methylcytosine 5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic
T5272 3-(3-Methoxyphenyl)propionic acid 3-Methoxybenzenepropanoic acid is a naturally occurring human metabolite, It is an organic acid and excreted in human urine.
T5273 2-Hydroxy-3-methylbutyric acid 2-Hydroxy-3-methylbutyric acid (2-hydroxyisovaleric acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothi
T5274 D-3-Phenyllactic acid Phenyllactic acid is a product of phenylalanine catabolism. An elevated level of phenyllactic acid is found in body fluids of patients with or phenylketonuria.
T5275 2,5-Furandicarboxylic acid 2,5-Furandicarboxylic acid is a normal urinary metabolite in humans. 2,5-Furandicarboxylic acid is also a microbial metabolite, a product of the oxidation of hydroxymethylfurfural
T5276 DL-Homocystine Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocy
T5277 3-Furoic acid 3-Furoic acid is an organic acid regularly occurring in the urine of healthy individuals. 3-Furoic acid is also a compound found in honey and honeydew samples.
T5278 5-Hydroxymethyl-2-furancarboxylic acid 5-Hydroxymethyl-2-furancarboxylic acid (Sumiki's acid) is a naturally occurring human metabolite. Sumiki's acid was first identified in the urine of a leukemia patient who was excr
T5279 Ethylmalonic acid Ethylmalonic acid can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid i
T5280 3-Chloro-L-Tyrosine 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particula
T5281 3-Methylindole 3-Methylindole, or skatole occurs naturally in feces (it is produced from tryptophan in the mammalian digestive tract), beets, and coal tar, and has a strong fecal odor. In low con
T5282 5-Methyluridine Ribothymidine is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy cont
T5283 NADH, disodium salt hydrate NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH becomes oxidized to produce NAD+
T5284 Ureidosuccinic acid Ureidosuccinic acid is an intermediary product in pyrimidine biosynthesis.
T5285 3-(Methylthio)propionic acid 3-methylthiopropionate is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts d
T5286 Glycyl-glycine Glycylglycine (Gly-Gly) is a dipeptide used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptide
T5287 N-Acetyl-L-aspartic acid N-Acetylaspartic acid is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from t
T5288 Cytidine 5'-triphosphate (disodium salt) Cytidine 5'-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases
T5289 N-Acetyl-L-arginine dihydrate N-alpha-Acetylarginine is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population.
T5290 L-(-)-3-Phenyllactic acid L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase
T5291 Malonic acid Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport ch
T5292 N-Acetyl-L-tyrosine Acetyltyrosine is a side chain reaction of tyrosine. It converts to tyrosine and then can be used in neurotransmitter treatment as a precursor of cathecholamine.
T5293 Maltotriose Maltotriose is a common oligosaccharide metabolite found in human urine after maltose ingestion or infusion. Maltotriose is increased in Glycogen storage disease II due to a mutati
T5294 (S)-Leucic acid Hydroxyisocaproic acid is an end product of leucine metabolism in human tissues such as muscle and connective tissue. It belongs to 2-hydroxycarboxylic acid group of amino acid met
T5295 1-Octadecanol Octadenol is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardati
T5297 3-Indolepropionic acid Indole-3-propionic acid (IPA, indole-3-propionate, or indolepropionic acid), is a deamination product of tryptophan formed by symbiotic bacteria in the gastrointestinal tract of ma
T5298 4-hydroxy-3-methylbenzoic acid 4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.
T5300 Ammonium formate Formic acid is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron tr
T5301 Crotonic acid Crotonic acid is fatty acid formed by the action of fatty acid synthases from acetyl-CoA and malonyl-CoA precursors. It is involved in the fatty acid biosynthesis. It is also found
T5302 D-Proline D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids ma
T5303 Isethionic acid sodium salt 2-Hydroxyethanesulfonate (2-Hydroxyethanesulfonic acid or isethionic acid) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals
T5305 Senecioic acid Senecioic acid appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid
T5306 H-Abu-OH L-alpha-Aminobutyric acid, also known as (S)-2-aminobutanoic acid, homoalanine, 2-AABA, ethylglycine, or L-butyrine, is a member of the class of compounds known as L-alpha-amino ac
T5307 Methylamine hydrochloride Methylamine occurs endogenously from amine catabolism and its tissue levels increase in some pathological conditions, including diabetes. Interestingly, methylamine and ammonia lev
T5308 Ortho-Hydroxyphenylacetic acid ortho-Hydroxyphenylacetic acid (2-hydroxybenzeneacetic acid) can be found in a number of food items such as natal plum, lemon verbena, half-highbush blueberry, and parsley, which m
T5309 Dimethylamine hydrochloride Dimethylamine (DMA) is abundantly present in human urine. Main sources of urinary DMA have been reported to include trimethylamine N-oxide, a common food component, and asymmetric
T5311 Crocin (Gardenia Fruits Extract)(42553-65-1) Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidem
T5314 pyridoxal isonicotinoyl hydrazone Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.
T5317 Cridanimod Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
T5320 Tulipalin A Tulipalin A (2-Methylenebutyrolactone) which has some phytotoxicity is a natural compound extracted from Tulipa gesneriana.
T5325 Nifurtimox Nifurtimox is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi epimastigotes, respectively).
T5326 Sugammadex (sodium) Sugammadex, a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.
T5334 VL285 VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
T5335 S-Gboxin S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM, IC50: 470 nM).
T5337 IACS-10759 IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
T5340 MPO-IN-28 MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
T5344 SP-420 SP-420 is a novel orally active iron chelator.
T5345 V-9302 V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).
T5352 GLYCODEOXYCHOLIC ACID Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.
T5357 ARN 272 ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).
T5359 RCGD423 RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
T5370 DL-Dithiothreitol DL-Dithiothreitol (DTT) is a reagent for maintaining SH groups in the reduced state.
T5371 L-BUTHIONINE-(S,R)-SULFOXIMINE L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GS
T5374 NAcM-OPT NAcM-OPT is a specific, reversible inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 (IC50: 79 nM).
T5383 D3-βArr D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
T5401 GSK2983559 GSK 2983559 (RIP2 kinase inhibitor 1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
T5402 DDR1-IN-2 DDR1-IN-2 (DDR1 inhibitor 7rh) is a potent, selective, ATP-competitive Discoidin domain receptor 1 (DDR1) inhibitor (IC50: 6.8 nM in cell-free kinase assays).
T5404 DDD107498 succinate DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).
T5406 SNAP-94847 SNAP-94847 is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice.
T5415 γ-GT γ-GT is used as a synthetic substrate for gamma-glutamyltransferase (GGT) to determine GGT activity.
T5419 DDD107498 DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).
T5420 Cycloguanil hydrochloride Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms,
T5421 KDU691 KDU691 is a PI4K inhibitor.
T5422 CID1375606 CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. characterized by a high level of conservation among vertebrates and a predominant expression in the c
T5424 Etosalamide Etosalamide is an antipyretic and analgesics agent.
T5425 ML367 ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity
T5445 2-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi NA
T5447 Anle138b Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease
T5448 Clanfenur Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.
T5453 3-methyl toxoflavin 3-methyltoxoflavin is an effective inhibitor of protein disulfide isomerase (PDI) and its IC50 value is 170 nM.
T5455 HT-2157 HT-2157 is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).
T5457 SN6 SN 6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)
T5463 AZD 3241 Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain
T5464 JNJ-10229570 JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-speci
T5468 YF-2 YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM and 49.31 μM , r
T5469 K-Ras-IN-1 K-Ras-IN-1 is a K-Ras inhibitor.
T5470 LAZABEMIDE LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T5477 ELQ-300 ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)
T5478 SRI 31215 SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s o
T5481 TRi-1 TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
T5486 RU320521 RU.521 (RU320521) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
T5493 Pyronaridine Pyronaridine also known as Malaridine, is an antimalarial drug.It inhibits the growth of P. falciparum during the asexual stage and early gametocyte stages (I and II) with an IC50
T5516 diABZI STING agonist-1 trihydrochloride diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
T5521 U-54461 Bropirimine (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.
T5522 NMDAR antagonist 1 NA
T5534 LOC14 LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM)
T5536 SJA710-6 SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells.
T5543 TriacetonaMine Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocyte. Triacetonamine
T5546 Helecin Helicin is a beta-D-glucoside resultng from the oxidation of the benzylic hydroxy group of salicin to the corresponding aldehyde. It has a role as a metabolite. It is a member of b
T5548 (-)-Verbenone (-)-Verbenone is an important component of the essential oil from rosemary. It is also an insect pheromone with a spicy odor and camphoraceous fragrance.
T5549 Melamine Melamine is a widely-used intermediate, mainly employed as a raw material for producing melamine resin. It is also a metabolite of cyromazine formed in the body of mammals who have
T5550 2-Hydroxy-2-methylbutanoic acid 2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease.
T5551 Levulinic acid Levulinic acid, derived from the degradation of cellulose, is a precursor for the synthesis of biofuels, such as ethyl levulinate.
T5554 1,3,5-Trimethoxybenzene 1,3,5-trimethoxybenzene is a methoxybenzene carrying methoxy groups at positions 1, 3 and 5. It has been found to be a biomarker of flavonoid consumption in humans. It has a role a
T5556 5a-Pregnane-3,20-dione 5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone
T5557 Propylparaben Propylparaben is an antimicrobial agent, preservative, flavouring agent
T5559 Carboxine Carboxin appears as off-white crystals. Systemic fungicide and seed protectant.
T5560 Dicyclanil Dicyclanil, a regulator of insect growth, is a veterinary medicine for the protection against early-season myiasis.
T5562 Methyl nicotinate Methyl nicotinate is the methyl ester of that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The act
T5563 Cyclohexanecarboxylic Acid Cyclohexanecarboxylic acid is a flavouring ingredien
T5564 Tricarballylic acid Tricarballylic acid is an inhibitor of aconitase
T5565 Undecanedioic acid Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin.
T5566 Ethyl maltol Ethyl Maltol is an extract from medicinal plants such as P. Incarnata and can be used as an anticonvulsant. It is also a common flavoring.
T5567 Tetradecanedioic acid Tetradecanedioic acid is a C14 dicarboxylic acid.
T5568 H-Tyr(3-I)-OH H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones
T5569 3-Amino-4-methylpentanoic acid Beta-leucine is a beta-amino acid that is pentanoic acid substituted at positions 3 and 4 by amino and methyl groups respectively. It has a role as a human metabolite.
T5571 Forchlorfenuron (KT-30, CPPU) Forchlorfenuron is plant growth regulator and cytokinin; can be used to increase fruit size of fruits.
T5572 2-Benzoxazolinone 2-Benzoxazolol is found in cereals and cereal products. 2-Benzoxazolol is found in rye seedlings.
T5573 Coenzyme Q9 Coenzyme Q9 (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.
T5578 L-Gulono-1,4-lactone L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vitamin) C.
T5580 Potassium 1-Naphthaleneacetate 1-Naphthaleneacetate is used as a plant Growth Regulator that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fung
T5581 Triacanthine Triacanthine, which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic.
T5582 Apocarotenal Apocarotenal (trans-β-apo-8'-carotenal) is a carotenoid found in spinach and citrus fruits. Apocarotenal is used in fat-based food (margarine, sauces, salad dressing), beverages,
T5583 D-(+)-Turanose D(+)-Turanose is a naturally occuring compound. It is a reducing disaccharide.
T5584 Sodium phytate hydrate Sodium phytate is known to function as a [PO4]3- storage depot and a precursor for other inositol phosphates and pyrophosphates. It is a potent chelator of divalent and trivalent c
T5587 CGP71683 hydrochloride CGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes
T5588 cis,cis-Muconic acid cis,cis-Muconic acid is a naturally-occurring organic acid. It is used in the manufacture of several widely-used consumer plastics. Its microbial production via extending the shiki
T5589 H-Gly-Pro-OH H-Gly-Pro-OH is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism
T5590 2-(4-Methoxyphenyl)acetic acid 2-(4-Methoxyphenyl)acetic acid is a plasma metabolite, found in normal human urine, cerebrospinal fluid, and brain tissue.
T5592 Acetosyringone Acetosyringone(AS) is a phenol secreted by wounded plant tissues.Acetosyringone is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions.
T5593 Ala-Gln Ala-Gln, a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glut
T5595 Tropine Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a variety of bioactive
T5596 2-Acetylpyrazine 2-Acetylpyrazine is a flavoring ingredient. 2-Acetylpyrazine is an avolatile flavor constituent of wheat and rye bread crust.
T5598 cis-3-Hexenyl hexanoate cis-3-Hexenyl hexanoate, existing in some fruit, has strong diffuse fruit aroma.
T5599 Hexyl hexanoate Hexyl hexanoate is found in alcoholic beverages. Hexyl hexanoate is used in fruit flavouring. Hexyl hexanoate is present in many fruits, Parmesan cheese, alcoholic beverages and bl
T5601 6-Fluoro-1,2-benzoisothiazol-3(2H)-one NA
T5603 Phthalic acid Phthalic acid is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.
T5607 Geranyl acetate Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.
T5609 3-Methylbutanoic acid 3-Methylbutanoic acid is a naturally occurring aroma compound found in Bartlett pear brandies, vanilla beans, rape-honey, and banana.
T5613 Squalane Squalane is a naturally occurring lipid in both plants and animals. It is usually used as a moisturizer and emollient in cosmetics manufacturing.
T5614 3-Oxopentanedioic acid 3-oxoglutaric acid or acetonedicarboxylic acid is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found to be a microbial metaboli
T5615 Benzyl acetate Benzyl acetate is a constituent of Jasmin and of the essential oils of ylang-ylang and neroli.
T5616 Diethyl malonate Diethyl malonate is naturally occurring in grapes and strawberries.
T5619 1,2-Propanediol Propylene Glycol is a propanediol that consists of propane where the hydrogens at positions 1 and 2 are substituted by hydroxyl groups AND often used as an excipient in medicines
T5620 Fenchyl Alcohol Fenchol is a hop-derived aroma compound commonly found in beer.
T5623 Bisphenol A Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It ex
T5624 Bisphenol B Bisphenol B has a binding affinity for estrogen receptors.
T5626 Atrazine Atrazine is an herbicide that does not occur naturally,and is a selective triazine herbicide. Atrazine is also a potent endocrine disruptor.
T5627 Methoxychlor Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca²⁺ homeostasis and cell viability in different cell models.
T5628 p-cumylphenol p-cumylphenol can treat R enal Tubular Cyst Formation in Newborn Rats.
T5629 2-tert-Butyl-4-ethylphenol NA
T5637 Triflumuron Triflumuron is an insecticide belonging to the group of so-called insect growth regulators. It inhibits the synthesis of chitin by the insect larvae, causing the die.
T5638 novaluron Novaluron is a benzoylurea insecticide, a member of monochlorobenzenes, an aromatic ether and an organofluorine compound.
T5639 lufenuron Lufenuron is a chitin-synthesis inhibitor.
T5641 RP-54745 RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
T5645 Nerol Nerol is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
T5646 Cinnamic acid Cinnamic acid has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, pro
T5647 6-Methylcoumarin 6-Methylcoumarin (6MC) is a semisynthetic coumarin with important in vitro and in vivo anti-inflammatory activity.
T5649 4-Allylanisole 4-Allylanisole is found in allspice,and is a constituent of many essential oils. 4-Allylanisole is a flavouring agent.
T5650 2,2':5',2''-Terthiophene 2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor
T5651 Phenyl benzoate Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.
T5653 Cinnamyl acetate Cinnamyl acetate is a naturally occuring compound used as a flavouring agent.
T5654 Musk ketone Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer c
T5657 3,4-Dimethoxybenzaldehyde 3,4-Dimethoxybenzaldehyde has antifungal activity .It is found in Cymbopogon javanensis.
T5658 Adamantane The adamantane moiety is the structural backbone of numerous compounds and the physicochemical and biological properties of organic polyhedral compounds with practical application
T5659 2-Adamantanone 2-Adamantanone is a bioactive chemical.
T5661 Methyl isoeugenol methyl isoeugenol (MIE) is a natural food flavour that constitutes 93.7% of an essential oil from Pimenta pseudocaryophyllus leaf. The leaf extracts of this species are used as a c
T5662 5-Hydroxy-1-tetralone 5-hydroxy-1-tetralone as the fluorescent labeling reagent.
T5663 Lactose Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osmotic regulator of l
T5664 Bovine albumin Bovine albumin is a globular protein that is used in numerous biochemical applications.
T5665 Geraniol geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.
T5666 Dipotassium glycyrrhizinate Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.
T5667 Acetic acid octyl ester Acetic acid octyl ester is the acetate ester of octan-1-ol. It has a role as a plant metabolite.Acetic acid octyl ester is present in citrus peel oils.
T5669 Citric acid monohydrate Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It mai
T5670 Isobutylparaben Isobutylparaben is a preservative and preservative insecticide.
T5671 Isophorone Isophorone is a clear liquid that smells like peppermint. It can be dissolved in water and evaporates somewhat faster than water.
T5672 Isophorone Isophorone (3,5,5-trimethyl-2-cyclohexen-1-one), a monoterpene, and the structurally related 1,8-cineole and camphor, have demonstrated a protective effect against cancer, biologic
T5674 H-151 H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
T5682 6-Hydroxyindole NA
T5683 (2R,3S)-3-Phenylisoserine hydrochloride NA
T5684 Ethyl 3,4-dihydroxybenzoate Ethyl 3,4-dihydroxybenzoate(EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.
T5686 Isopropylparaben Isopropylparaben is a preservative and preservative insecticide.
T5689 20-DEOXYINGENOL 20-DEOXYINGENOL is a natual product.
T5692 Pyrroloquinoline quinone Pyrroloquinoline quinone (PQQ), as a well-known redox enzyme cofactor, PQQ can protect NS/PCs against glutamate toxicity associated with ROS-mediated mitochondrial pathway,
T5693 Methoxatin disodium salt Methoxatin disodium salt, an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic
T5694 Usnic Acid sodium Usnic Acid sodium is a natual product.
T5695 Dimethyl malonate Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.
T5696 Dimethyl succinate Dimethyl succinate is found in nuts. Dimethyl succinate is present in roasted filberts. Dimethyl succinate is a flavouring ingredient.
T5697 BMS1166 BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
T5703 β,β-Dimethylacrylalkannin β,β-Dimethylacrylalkannin is a natural product isolated from Arnebia nobilis Reichb.f, increases collagen and involucrin content in skin cells.
T5704 (E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]- (E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]- has Anti-inflammatory, analgesic function.
T5706 8-epidiosbulbin E acetate 8-Epidiosbulbin E acetate (EEA), a furanoid, was unexpectedly found to be the most abundant diterpenoid lactone in certain varieties of Dioscorea bulbifera L. (DB), a traditional h
T5707 GALANGIN-3-METHYLETHER GALANGIN-3-METHYLETHER has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the
T5710 Pinocembrin 7-O-beta-D-glucoside Pinocembrin 7-O-beta-D-glucoside is a natual product isolated from Penthorum chinense Pursh.
T5711 Methylnissolin-3-O-glucoside Methylnissolin-3-O-glucoside has anti-inflammatory effects,antioxidant activity.
T5712 zerumbone Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activi
T5713 2"-O-β-L-Galorientin 2"-O-β-L-Galorientin is a natual product isaolated from Trollius chinensis Bunge.
T5718 L-ABRINE L-ABRINE is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.
T5719 Vitexia-glucoside Vitexia-glucoside is a natural product isolated from Briza stricta.
T5720 Boldine Boldine is a natual product .Boldine displays anti-cancer, cytoprotective , anti-oxidant and anti-inflammatory activities.
T5723 DL-Menthol DL-Menthol is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.
T5724 neo-gambogic acid Neogambogic acid , an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of pro
T5726 Specneuzhenide Specneuzhenide is a phenol glycoside isolated from Ligustrum sinense. Specneuzhenide (Nuezhenide) possesses anti-tumor activity,has anti-angiogenic and vision improvement effects.
T5728 OsMundacetone OsMundacetone is a natual product isolated from Rhizoma osmundae.
T5730 MALTOHEXAOSE MALTOHEXAOSE is a natural saccharide, and can be produced from amylose, amylopectin and whole starch.
T5731 1-Kestose 1-Kestose shows significant anti-hydroxyl radical potential. 1-Kestose can promote intestinal Lactobacillus number, and influence the microorganisms as well as the intestinal and s
T5733 Xylotetraose Xylotetraose is a hydrolysis product of Xylan. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose.
T5735 Deacetyl asperulosidic acid methyl ester Ddeacetyl asperulosidic acid methyl ester is a natual product isolated from the herbs of Hedyotis diffusa Willd,it can lower the blood glucose level in normal mice.
T5737 euphol Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
T5738 7-Epi-10-deacetyltaxol 7-Epi-10-deacetyltaxol shows IC50 values of 0.085 nM, against HeLa cells.
T5740 (25RS)-Ruscogenin (25RS)-Ruscogenin is a natual product.
T5741 Pseudolaric acid B-glucopyranoside Pseudolaric acid B-glucopyranoside is a natural product from Pseudolarix amabilis.
T5742 Isodemethylwedelolacton Isodemethylwedelolacton is a natual product,has Clotting activity.
T5747 ISOBERGAPTEN ISOBERGAPTEN is a plant growth regulating substance, it is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum maximum; it may form
T5748 AIDS031406 AIDS031406 is a natural product Psychotria ipecacuanha.
T5749 7-Xylosyl-10-deacetyltaxol 7-Xylosyl-10-deacetyltaxol paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.
T5750 Oxyberberine Oxyberberine is isolated from the methanol extract of A. mexicana. It has been used to study the SW480 human colon cancer cell line.
T5751 Tigogenin Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development o
T5752 Gipsoside Gipsoside is a natural product.
T5754 Kavain Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors
T5756 Hastatoside Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity.
T5760 SINOACUTINE SINOACUTINE is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.
T5761 Notoginsenoside Ft1 Notoginsenoside Ft1 is a saponin originally isolated from P. notoginseng with diverse biological activities
T5762 REBAUDIOSIDE B(P)(NEW) REBAUDIOSIDE B tastes about 150 times sweeter than sucrose and it is non-caloric.
T5763 Sedanolide Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.
T5765 ranaconitine Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
T5766 Coclaurine Coclaurine is a natural product.
T5767 Isovanillic acid Isovanillic acidis is a natural product isolated from Senecio scandens, and shows distinct anti -inflammatory activities.
T5770 Alisol B Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited R
T5772 1F-fructofuranosylnystose 1F-Fructofuranosylnystose is a kind of Fructooligosaccharides which are naturally occurring sugars with potentially beneficial nutritional effects.
T5777 Phaseoloidin Phaseoloidin, a homogentisic acid glucoside from Nicotiana attenuata trichomes, contributes to the plant's resistance against lepidopteran herbivores.
T5781 taraxasteryl acetate Taraxasterol acetate has anti-inflammatory activity in bino rats against carrageenan, formaldehyde and adjuvant induced inflammations. Taraxasterol acetate also displays potential
T5783 Rosamultin Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.
T5789 XYLOTRIOSE XYLOTRIOSE is a natural xylooligosaccharide, acts as a bifidogenic factor.
T5790 1,1,1,1-Kestohexose 1,1,1,1-Kestohexose is a natural product isolated from Poa ampla.
T5791 Fructoheptasaccharide Fructoheptasaccharide belongs to fructooligosaccharides (FOS) with degree of polymerization (DP=7).
T5792 Rebaudioside M Rebaudioside M is a natural non-calorie sweetener isolated from Stevia rebaudiana Bertoni,is a glycoside of the ent-kaurene diterpenoid aglycone.
T5795 Suberosin Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal a
T5799 Arecaidine hydrochloride Arecaidine hydrochloride may have carcinogenesis.
T5801 praeruptorin C Praeruptorin C (Pra-C), an effective component in the root of Peucedanum praeruptorum dunn, a traditional Chinese medicine, may function in neuroprotection.
T5802 Stearyl glycyrrhetinate Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharm
T5803 D(-)-Tartaric acid D(-)-Tartaric acid found in many plants, particularly tamarinds and grapes,it is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administ
T5804 Pneumocandin B0 Pneumocandin B0 is a natural product and a key intermediate in the synthesis of the antifungal agent.
T5808 OXYPEUCEDANIN HYDRATE Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
T5809 Stachyose Stachyose is a natual product,it highly promotes proliferation of lactic acid bacteria (LAB) by inducing LAB to produce more α-galactosidase to hydrolyze stachyose.
T5811 HYOSCINE HYDROCHLORIDE HYOSCINE HYDROCHLORIDE versus placebo in preventing motion sickness has been shown to be effective.
T5812 Zinc Phytate NA
T5816 Qstatin QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species( SmcR with an EC50 of 208.9 nM).
T5821 BC-1215 BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release).
T5822 5-Benzylidene-3-ethyl rhodanine 5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
T5823 D-Lin-MC3-DMA D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
T5827 BI-6C9 BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.
T5834 Myrcene Myrcene is a terpene that has been found in Cannabis and has antioxidative properties.
T5836 Eprinomectin Eprinomectin is an avermectin with anthelmintic and insecticidal activities.
T5837 Tamerit Tamerit as an efficient inhibitor of oxidative burst in monocytes.
T5839 Phosalone Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide.
T5862 Ezatiostat Ezatiostat is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity.
T5873 2,6-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.
T5874 2-Methoxybenzoic acid 2-Methoxybenzoic acid is a novel antiemetic which prevents nausea and vomiting in humans.
T5875 4-Methoxycinnamic acid 4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissi.
T5879 TDCPP TDCPP is classified under the chlorinated trialkyl organophosphate flame retardant (OPFR) group of compounds primarily utilized as additives in commercial products.
T5882 3-Bromopyruvic acid 3-Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of pl
T5883 4-Ethylphenol 4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine.
T5885 N-Acetyl-D-galactosamine N-Acetyl-d-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.
T5888 5-Methoxysalicylic acid 5-Methoxysalicylic acid is a natural product, used as a useful matrix in the MALDI MS analysis of oligonucleotides when combined with spermine
T5889 Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 μM for mushroom tyrosinase.
T5890 2,4-Dihydroxybenzoic acid 2,4-Dihydroxybenzoic acid is found in alcoholic beverages.2, 4-Dihydroxybenzoic acid is a food flavour ingredient and flavour modifie.
T5891 D-ERYTHRO-SPHINGOSINE D-erythro-Sphingosine is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
T5912 5-Methylcytidine 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.
T5913 Sulbutiamine Sulbutiamine is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.
T5914 Folcisteine Folcisteine is a plant growth regulator.
T5915 D-chiro-Inositol D-chiro-Inositol is an epimer of myo-inositol that is found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bi
T5916 Fmoc-N-Me-Phe-OH Fmoc-N-Me-Phe-OH is a peptide inhibitor of Malaria Parasite
T5917 6-Methoxysalicylic acid 6-Methoxysalicylic acid may be employed as internal standard for the determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic acid (SA),and exhibits
T5939 Calcium dobesilate Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.
T5941 Anthraflavic acid Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor.
T5943 4,4'-DIMETHOXYBENZIL 4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
T5955 Tricyclazole Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor and a unique fungicide for control of Pyricularia oryzae on rice.
T5963 Menadione sodium bisulfite Menadione sodium bisulfite(MSB, also known as vitamin K3),is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K suppl
T5967 Ethacridine lactate Ethacridine lactate is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
T5968 DL-Homocysteinethiolactone hydrochloride DL-Homocysteinethiolactone hydrochloride is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing oxid
T5978 2,3-Diaminopropionic acid hydrochloride 2,3-Diaminopropionic acid hydrochloride is a competitive inhibitor of cystathionase (CTH).
T5979 1-beta-D-Arabinofuranosyluracil 1-beta-D-Arabinofuranosyluracil isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has anti-inflammatory activ
T5980 2-Ketoglutaric acid 2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
T5981 2,2'-Cyclouridine 2,2'-Cyclouridine is a research tool for antiviral and anticancer studies.
T5982 3-Methoxybenzoic acid 3-methoxybenzoic acid is a food additive,and has antibacterial activity.
T5983 o-Phenanthroline O-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-phenanthroline protects mammalian cell
T5984 Indole-3-carboxylic acid Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite .
T5986 3-Hydroxypicolinic acid 3-Hydroxypicolinic acid is a picolinic acid derivative, and belongs to the pyridine family.
T5987 Oxonic Acid (potassium salt) Oxonic Acid (potassium salt) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats.
T5988 Dimethyl biphenyl-4,4'-dicarboxylate Dimethyl biphenyl-4,4'-dicarboxylate is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis.
T5993 ARN-3236 ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nM respectively). ARN-3236 Has ant
T5994 KPT-6566 KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity.
T5A2461 Bufotaline 1. Bufotaline is a kind of poisonous secretions of toads.
T5S0018 Betulonic acid 1. Betulonic acid amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative
T5S0055 Chelidonine 1. Chelidonine isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelido
T5S0056 Coptisine chloride 1. Coptisine chloride can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
T5S0106 Peimisine 1. Peimisine can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth musc
T5S0229 Isosakuranetin 1. Isosakuranetin has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivit
T5S0246 Pseudoprotodioscin 1. Pseudoprotodioscin has moderate cytotoxicity.
T5S0273 Hypaphorine 1. Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases
T5S0285 Cistanoside A 1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-ove
T5S0384 Rhaponiticin 1. Rhaponticin(Rhaponiticin) can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice, indicates that rhaponticin has a noticeable antidiab
T5S0483 (-)-Syringaresnol-4-O-beta-D-apiofuranos It is a lignan glycosides from the bark of Albizzia myriophylla.
T5S0506 Rutundic acid Rotundic acid, a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), an
T5S0526 Rhodojaponin II 1. Rhodojaponin II correlates pretty well with cardiotoxicity.
T5S0527 Rhodojaponin III 1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin I
T5S0543 Isocurcumenol 1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
T5S0581 Sec-O-Glucosylhamaudol Sec-O-glucosylhamaudol has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal sec-
T5S0620 Dehydrotrametenolic acid 1. Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sen
T5S0636 Citric acid 1. Citric acid (1-2̵g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans
T5S0661 Koumine 1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic eff
T5S0662 Gelsemine 1. Gelsemine has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammato
T5S0669 Bergamotine 1. Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A<sup>y</sup>diabetic mice.
T5S0691 Shionone 1. Shionone has anti-tussive and anti-inflammatory effects.
T5S0733 Picroside III Picroside III, an iridoid glucoside found in the root of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae), and its subtype Picroside II has been demonstrated to reduce apopt
T5S0734 Desmethoxy yangonin 1. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The inducti
T5S0761 Nitidine chloride 1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro
T5S0788 Oroxin A Oroxin A has antitussive and expectorant effects.
T5S0802 Palmatine 1. Palmatine is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the trea
T5S0803 Columbamine 1. Columbamine shows strong activity with IC5 48.1 µM. 2. Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells w
T5S0836 Astrasieversianin VII Isoastragaloside II is a derivative Astragaloside I, an ingredient in Astragalus membranaceus which is reported to have osteogenic properties.
T5S0890 Oleandrin 1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin a
T5S0994 N-Methylcytisine 1. N-Methylcytisine's nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N,N-dimethylcytisine did not displace 14C-tuboc
T5S1028 3,29-Dibenzoyl Rarounitriol 3,29-Dibenzoyl karounitriol is a natural product from Trichosanthes kirilowii Maxim.
T5S1054 Wilforgine 1. Wilforgine exhibits insecticidal activity of some degree.
T5S1058 Triptonide 1. Triptonide is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregul
T5S1094 Forsythoside E Forsythoside E is a natutal product isolated from fruits of forsythia suspensa.
T5S1097 Neferine 1. Neferine has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase
T5S1099 Liensinine 1. Liensinine,a kind of isoquinoline alkaloid,can antagonize the ventricular arrhythmias.
T5S1131 Ganoderic acid C6 1. Ganoderic acid C6 has antinociceptive activity.
T5S1133 Ganoderic acid D 1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells
T5S1177 Aloin B 1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new vista
T5S1262 Methylophiopogonanone A 1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability
T5S1331 Herbacetin 1. Herbacetin induces apoptosis in HepG2 cells, by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting
T5S1408 (+)-Pteryxin (+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
T5S1413 Nodakenetin 1. Nodakenetin has clinical efficacy.
T5S1526 Apigenin 7-O-(2G-rhamnosyl)gentiobioside
T5S1550 Cinnamyl alcohol 1. Cinnamyl alcohol readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.
T5S1569 AKBA 1. 3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 1.5 m muM.
T5S1590 Notoginsenoside Fe Notoginsenoside Fe is a natural compound isolated from Panax japlcus var.
T5S1645 Apiopaeonoside Apiopaeonoside is a natural product isolated from the root of Paeonia suffruticosa
T5S1679 Acetylcimigenol 3-O-alpha-L-arabinopyran
T5S1708 Dendrobine 1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the
T5S1882 Napellonine 1. Napellonine shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.
T5S1889 Yunaconitine 1. Yunaconitine has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg
T5S1891 Acetylaconitine Analgesic activity.
T5S1897 Linderalactone 1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48̵µg/mL.
T5S1923 Schisandrin C Schisandrin C is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.
T5S1963 Orcinol gentiobioside
T5S1981 alpha-Cyperone 1. Alpha-Cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. Alpha-Cyperone significantly inhibited PGE2 production by
T5S1982 Periplocin 1. Periplocin has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used
T5S1989 Apiin 1. Apiin is the reducing and stabilizing agent. 2. Apiin has inhibitory activity in-vitro on iNOS expression and nitrite production when added before LPS stimulation in the medium
T5S2017 Ingenol 1. Ingenol mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compoun
T5S2073 Senkyunolide A Senkyunolide A is a useful standard compound for the quality evaluation and chemical differentiation between Rhizoma chuanxiong and Angelica sinensis, and suitable for the analysis
T5S2076 Senkyunolide I 1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.
T5S2139 Epimedin A1 Epimedin A1(Hexandraside F) is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.
T5S2205 Sibiricaxanthone B
T5S2207 7-O-Methylmangiferin 7-O-MethylMangiferin is an xanthone isolated from the rhizomes of Iris nigricans.
T5S2254 Swertianolin 1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. S
T5S2306 Hosenkoside A Hosenkoside A has antimicrobial effect.
T5S2309 Hosenkoside K Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.
T5S2343 Acetyl shikonin 1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effe
T5S2347 Deoxyshikonin 1. Deoxyshikonin may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular en
T5S2350 Acetoxyisovalerylalkannin
T6000 D-DELTA-TOCOPHEROL D-DELTA-TOCOPHEROL is an isomer of Vitamin E,has antioxidant activity,and might be useful as effective ingredients in whitening cosmetics with lower skin toxicity.
T6017 Linsitinib OSI-906 (Linsitinib) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib sel
T6060 (±) Anabasine (±) Anabasine is a biphasic muscle relaxant.
T6086 Clopamide Clopamide is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
T6088 Anidulafungin Anidulafungin (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.
T6105 phosphorylcholine Phosphorylcholine is an antigenic cell-surface component found on many commensal and pathogenic bacteria that reside in the upper airway.
T6112 Doxercalciferol Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
T6114 Nifursol Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
T6144 KB-R7943 KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
T6195 Baloxavir marboxil Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
T6201 NXY-059 NXY-059, a new-type nitrone, exhibits potently neuroprotective effects.
T6211 Posaconazole Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).
T6231 Tebipenem Pivoxil Tebipenem pivoxil, an orally activity carbapenem antibiotic, is utilized in treating otolaryngologic and respiratory infections.
T6232 Vilazodone HCl Vilazodone HCl,a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
T6245 BAPTA-AM BAPTA-AM is a selective, permeable free calcium chelator.
T6268 Ceftiofur hydrochloride Ceftiofur Hydrochloride is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activ
T6307 Lubiprostone Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.
T6344 Sevelamer HCl Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
T6349 Sitafloxacin Hydrate Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.
T6359 1-Hexadecanol 1-Hexadecanol, a fatty alcoholis, is utilized for making other chemicals.
T6361 3-Indolebutyric acid 3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
T6363 4μ8C 4μ8C(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.
T6374 Alfacalcidol Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.
T6375 Alibendol Alibendol is a choleretic, antispasmodic, and cholekinetic.
T6377 Aloperine Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
T6381 Amifostine trihydrate Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
T6385 Amoxicillin Sodium Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
T6395 Astragaloside A Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the therapy of cardiovascular diseases.
T6397 Atracurium besylate Atracurium besylate is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on g
T6398 Azaperone Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
T6401 Azithromycin Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
T6402 Azomycin Azomycin is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.
T6406 Besifloxacin HCl Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
T6409 SAR348830 NA
T6411 Biapenem Biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable ag
T6412 CVT-12012 CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).
T6414 Bisacodyl Bisacodyl is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation.
T6430 Calcifediol Calcifediol(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
T6431 Calcium Levofolinate Calcium Levofolinate, a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
T6437 Cefoperazone Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages
T6438 Cefoselis Sulfate Cefoselis is a widely used beta-lactam antibiotic.
T6439 Cetylpyridinium Chloride Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
T6443 Chloroprocaine HCl Chloroprocaine HCl is a local anesthetic during surgical procedures.
T6447 Clindamycin Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced
T6448 Clindamycin HCl Clindamycin Hydrochloride inhibits protein synthesis by acting on the 50S ribosomal. It is the hydrochloride salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum
T6449 Clindamycin palmitate HCl Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
T6451 Clodronate Disodium Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
T6452 Closantel Sodium Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals.
T6454 CORM-3 CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
T6460 Cysteamine HCl Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant.
T6467 Dexrazoxane HCl Dexrazoxane HCl is a cardio-protective drug.
T6468 D-glutamine D-glutamine,an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T6470 Diclofenac Potassium Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
T6471 Dicloxacillin Sodium Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.
T6472 Difluprednate Difluprednate(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.
T6473 Dioscin Dioscin is a saponin with antitumor activities.
T6475 DL-Carnitine HCl DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.
T6477 Domiphen Bromide Domiphen bromide is an antiseptic acting as a cationic surfactant.
T6480 D-Pantothenic acid D-Pantothenic Acid is a water-soluble vitamin ubiquitously found in plants and animal tissues with an antioxidant property. Vitamin B5 is a component of coenzyme A (CoA) and a part
T6482 Efaproxiral Sodium Efaproxiral Sodium ,a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer.
T6497 Fenoprofen Calcium Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
T6498 Fenoprofen calcium hydrate Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).
T6499 Fenticonazole Nitrate Fenticonazole Nitrate is an azole agent with antifungal activity.
T6506 FPH1 FPH1 (BRD-6125) can promote the expansion of iPS-derived hepatocytes.
T6512 Geneticin sulfate G-418 (disulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
T6520 Grape Seed Extract Grape Seed Extract is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important
T6523 Guanosine Guanosine is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism.
T6528 Gynostemma Extract Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum.
T6538 Hydroxypropyl Cellulose Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility, it is used as food additive and sieving matrix for DNA separations.
T6539 Ibandronate sodium monohydrate Ibandronate is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
T6544 Inulin Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.
T6549 Isepamicin sulfate Isepamicin Sulphate, an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase, inhibits bacterial protein synthesis by targeting
T6550 Isoconazole nitrate Isoconazole nitrate (Travogen) is an azole antifungal reagent.
T6551 Isosorbide Isosorbide is a heterocyclic compound that is derived from glucose, used as a diuretic.
T6559 L-(+)-Rhamnose Monohydrate L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.
T6560 Lappaconite HBr Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.
T6561 Laquinimod Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
T6569 L-Mimosine L-Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
T6576 Malotilate Malotilate is a medicine used for the therapy of liver cirrhosis.
T6581 Methyclothiazide Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.
T6584 MG149 in clinically as an antihypertensive.
T6586 Mildronate dihydrate Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
T6596 Morin Hydrate Morin hydrate(Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).
T6599 N6-methyladenosine N6-Methyladenosine is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary n
T6601 Nanchangmycin Nanchangmycin, a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals
T6606 Nicaraven Nicaraven, a hydroxyl radical scavenger, has neuroprotective and antivasospastic effects.
T6622 Oxacillin sodium monohydrate Oxacillin sodium monohydrate is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
T6623 Oxibendazole Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in hor
T6624 Oxytetracycline Dihydrate Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
T6630 Quercetin Dihydrate Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and
T6640 Ribitol Ribitol is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
T6641 Rilmenidine Phosphate Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
T6654 Sapogenins Glycosides <p>Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L.,
T6664 SecinH3 SecinH3 is selective cytohesin inhibitor.
T6665 Sertaconazole nitrate Sertaconazole nitrate, a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.
T6666 Sevelamer Carbonate Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as t
T6670 Silymarin Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
T6674 Sodium ascorbate Sodium Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
T6675 Sodium Picosulfate Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.
T6681 STF-083010 STF-083010 is a selective inhibitor of the IRE1α endonuclease.
T6686 Sulconazole Nitrate Sulconazole Nitrate is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole nitrate inhibits fungal cytochrome P-450 ste
T6705 TIC10 Isomer TIC10 Isomer is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, super
T6706 Ticarcillin sodium Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
T6710 Troxipide Troxipide, a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach
T6715 Valnemulin HCl Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
T6717 Vanillin Vanillin is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.Vanillin can reversibly and non-competitively inhibit t
T6736 Zafirlukast Zafirlukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.
T6741 SPDP SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bond
T6742 2-Deoxy-D-glucose 2-Deoxy-D-glucose is an analog of glucose, which is a glycolytic inhibitor with antiviral activity.
T6743 4-Hydroxytamoxifen 4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of br
T6751 Acetylcholine iodide Acetylcholine iodide is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and
T6775 BAY 41-2272 BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.
T6793 BRD7552 BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.
T6794 Bromodeoxyuridine Bromodeoxyuridine (BrdU), a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.
T6798 Tretazicar CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0
T6800 CCF642 CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
T6802 CFSE Carboxyfluorescein succinimidyl ester (CFSE) is a fluorescent cell staining dye. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecul
T6805 Choline bitartrate Choline bitartrate is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acet
T6820 Disodium (R)-2-Hydroxyglutarate Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
T6821 Dp44mT Dp44mT,a effective iron chelator, has selective antitumor activity.
T6833 Favipiravir Favipiravir (T-705), an effective and selective RNA-dependent RNA polymerase inhibitor, are applied to treat influenza virus infections.
T6834 FCCP FCCP, a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes leading to disrupts ATP synthesis.
T6851 NADP sodium salt NADP sodium salt is a coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions.
T6855 HA15 HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resis
T6863 Isosorbide Mononitrate Isosorbide mononitrate is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.
T6871 L-Glutamic acid monosodium salt L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods.
T6873 Lauric Acid Lauric Acid,which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coc
T6881 LTX-315 LTX-315, the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.
T6929 Pantoprazole sodium Pantoprazole Sodium is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal ce
T6956 Protirelin Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
T6968 Riociguat Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
T6969 Imidacloprid Imidacloprid is a systemic chloronicotinyl insecticide, which can be effectively used in agriculture to control pests .
T6981 Nudifloric Acid Nudifloric Acid is from Cordyceps bassiana. Nudifloric Acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function.
T6985 Benzo[a]pyrene Benzo[a]pyrene shows lung carcinogenicity in mice in a dose-dependent manner.
T6991 Sodium Nitroprusside Dihydrate Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.
T6992 Sodium sulfadiazine Sodium Sulfadiazine is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.
T6993 Sodium Tauroursodeoxycholate (TUDC) Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
T6998 Tedizolid Phosphate Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
T6999 Teneligliptin hydrobromide Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC
T6S0033 Crotonoside 1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats,in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig
T6S0052 Chelerythrine 1. Chelerythrine may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has po
T6S0071 Fraxinellone 1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of i
T6S0084 Tuberstemonine 1. Tuberstemonine exhibits relatively higher intestinal permeabilities. 2. Tuberstemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction.
T6S0095 Genkwanin 1. Genkwanin exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug
T6S0105 Peiminine 1. Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
T6S0107 Peimine 1. Peimine has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB sign
T6S0109 Sipeimine 1. Sipeimine has antiasthmatic effect,on tracheal M receptor antagonist. 2. Sipeimine can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve to
T6S0119 Dauricine 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood̽brain barri
T6S0141 Corylin Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
T6S0214 Maackiain 1. Maackiain induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.
T6S0221 Eriocitrin 1. Eriocitrin is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of hig
T6S0232 Eriodictyol 1. Eriodictyol is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improvin
T6S0234 Toosendanin 1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocy
T6S0325 Glycitein 1. Gycitein has weak estrogenic activity. 2. Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
T6S0413 Pectolinarigenin 1. Pectolinarigenin exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eic
T6S0627 Mesaconitine 1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
T6S0654 Isocorynoxeine 1. Isocorynoxeine shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant n
T6S0657 Isorhyncophylline 1. Isorhyncophylline and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hyperten
T6S0659 Rhynchophylline 1. Rhynchophylline can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can
T6S0721 Orientin 1. Orientin may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vas
T6S0735 Flavokawain B 1. Flavokawain B has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic cons
T6S0743 Sesamoside Sesamoside has antinociceptive activity.
T6S0781 Phellodendrine 1. Phellodendrine has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.
T6S0920 2''-O-Galloylhyperin 2''-Galloylhyperin found in Pyrola. It increases ruminal fiber fermentability by formed wall-bound lignin in primary maize cell walls.
T6S1027 Tussilagone 1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent f
T6S1101 Astragalin 1. Astragalin may be a potential agent in the treatment of osteoarthritis. 2. Astragalin can be effective in allaying ROS-promoted bronchial fibrosis through inhibiting autophagoso
T6S1256 Ruscogenin 1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner,2. Ruscogenin inhibited adhesion o
T6S1292 Levistilide A 1. Levistilide A inhibits liver fibrosis and angiogenesis.
T6S1294 Nicotiflorin 1. Nicotiflorin has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and
T6S1302 Carnosol 1. Carnosol has anti-oxidative,anti-inflammatory,antiproliferative and apoptosis inducing properties. 2. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemot
T6S1315 Oroxylin A 1. Oroxylin A has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6
T6S1423 Praeruptorin B 1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.
T6S1435 Notopterol 1. Notopterol induces apoptosis and inhibits cell cycle-specific.
T6S1440 Loganic acid 1. Loganic acid and geniposide exhibit both sides effect on superoxide generation.
T6S1485 Ginsenoside Rh4 1. Ginsenoside Rh4 could be safely used as adjuvant with low or non-haemolytic effect. 2. Ginsenoside Rh4 has cytotoxic activity and its aglycone against cancer cell lines.
T6S1495 Ginsenoside Rk3 1. Ginsenoside Rk3 and Rh4 could have a role in treating inflammatory diseases. 2. Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic hea
T6S1543 Dehydrodiisoeugenol 1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehyd
T6S1559 Aurantio-obtusin 1. Biotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation. 2. Aurantio-obtus
T6S1572 Sauchinone 1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent
T6S1579 Monotropein 1. Monotropein has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition
T6S1587 Notoginsenoside R2 Notoginsenoside R2 has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathway
T6S1597 Mulberroside A 1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberros
T6S1653 Albiflorin 1. Albiflorin has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantl
T6S1657 Paeonolide
T6S1665 Irisflorentin 1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Ir
T6S1676 Cimigenoside
T6S1740 Nardosinone 1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could
T6S1780 Protosappanin B 1. Protosappanin B significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the
T6S1784 Brazilin 1. Brazilin exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated
T6S1842 Tenacissoside G
T6S1843 Tenacissoside I Tenacissosides B, C, I and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner.
T6S1844 Tenacissoside H Tenacissoside H has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
T6S1917 Gomisin A 1. Gomisin A may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways
T6S1918 Schisantherin B 1. Schisantherin B shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
T6S2023 Harpagoside 1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-i
T6S2116 Ginkgolic acid C17:1 1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membrane
T6S2123 Ginkgolic acid C15:1 1. Ginkgolic acid C15:1 represses curli genes and prophage genes in EHEC.
T6S2140 Anhydroicaritin 1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariec
T6S2146 Epimedin B 1. Epimedin B has potential activity against osteoporosis by stimulating osteoblasts.
T6S2227 Spinosin 1. Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activit
T6S2238 Eupalinolide A Eupalinolide A has the effects of relieving phlegm and relieving cough, clearing away heat and detoxification, diuretic swelling and reducing blood pressure.
T6S2243 Alisol A 24-acetate 1. Alisol A 24-acetate has been determined for the quality control of this crude drug.
T6S2246 Alisol B 23-acetate 1. Alisol B 23-acetate produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acet
T6S2247 Alismoxide 1. Alismoxide has anti-inflammatory effects.
T6S2252 Sweroside 1. Sweroside possesses strong hepatoprotective effect. 2. Sweroside is a promising osteoporosis therapeutic natural product, has anti-osteoporotic effect on the human MG-63 cells
T6S2391 Chicoric acid 1. Cichoric acid has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. 2. Chico
T7001 TIC10 TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacok
T7024 Qingyangshengenin Qingyangshengenin is a steroid used in the preparation of antiepileptic agents.
T7027 EURYCOMANONE Eurycomanone is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibit
T7034 1-IODOADAMANTANE 1-Iodoadamantane is employed in the free-radical carbonylation reactions with alkenes.
T7036 2,4'-Dihydroxybenzophenone 2,4-dihydroxybenzophenone (BP-1) can effectively protect C57BL/6J mice from APAP-induced hepatotoxicity. BP-1 has a protective effect on acute hepatotoxicity and neurotoxicity of m
T7037 7-Acetoxy-4-methylcoumarin 7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell m
T7038 4-Methylayapin NA
T7047 Dipalmitin Dipalmitin has templating effects on soft palm mid fraction crystals.
T7049 Herniarin Herniarin is a natural coumarin with antitumor effect.
T7050 alpha-Tocopherolquinone During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has also displayed antiox
T7054 N-Benzoyl-(2R,3S)-3-phenylisoserine (2R, 3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel used to study the location of the binding sites. It shows cytotoxic,
T7055 Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate NA. Medical intermediate
T7063 Oxymetholone Oxymetholone is an anabolic androgenic steroid and synthetic derivative of testosterone. Formulations containing oxymetholone are used in the treatment of anemias caused by deficie
T7075 2-Chloronaphthoquinone 2-Chloro-1,4-naphthoquinone is a substituted naphthoquinone which is used as an insecticide and acaricide.
T7086 TBTA TBTA is a tertiary amine with three 1,2,3-triazole groups. It complexes with, and stabilizes, copper(I) to accelerate azide-alkyne cycloadditions, as used in click chemistry.
T7087 TCEP HCl Tris(2-carboxyethyl)phosphine hydrochloride may be employed as a catalyst for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It may be used as a reducing ag
T7091 N-Formyl-Met-Leu-Phe N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
T7092 NADPH tetrasodium salt NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reaction
T7094 Levomefolic Acid Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functi
T7095 Hexacosanoic acid Hexacosanoic acid, a very long-chain fatty acid, is related to adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
T7098 BAPTA BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.
T7099 Gefarnate Gefarnate is a synthetic compound used for the treatment of gastric ulcers,and also used in the treatment of dry eye syndrome.
T7105 Zinc phthalocyanine
T7106 Menaquinone-4 Menaquinone-4 is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.
T7108 Noopept Omberacetam is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compou
T7109 TMB-PS TMB-PS is a chromogenic reagent for the detection of hydrogen peroxide e.g. in the enzymatic analysis of body fluids.
T7115 Pymetrozine Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae .
T7116 Sodium gualenate Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects.
T7117 Sapropterin Hydrochloride Sapropterin dihydrochloride is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.
T7118 Dimethocaine Dimethocaine is a local anesthetic with reported stimulant properties most similar to cocaine.
T7121 Sulfachloropyrazine sodium Sulfachloropyrazine sodium is an antiprotozoal,with antibacterial and anticoccidial effects
T7124 Dinotefuran Dinotefuran is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves d
T7126 Hydroquinine Hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.
T7132 BRASSINAZOLE Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a
T7134 MYK-461 MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
T7138 FB23-2 FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).
T7142 Cephalosporin C zinc salt Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM), and this inhibition was largely attributable to the presence of zinc.
T7143 Alagebrium chloride Alagebrium Chloride is an advanced glycation end product (AGE) inhibitor, and has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patient
T7144 BTS BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
T7145 NSC139021 NSC139021 is a Rio2 kinase (RIOK2) inhibitor that inhibits ERG protein.
T7146 Piperazine adipate Piperazine adipate is a potent broad spectrum anthelmintic.
T7154 trans-trans-Muconic acid trans-trans-Muconic acid is a urinary metabolite of benzene.
T7156 NIBR189 NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)
T7174 Urolithin A Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
T7181 IDO-IN-1 IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)
T7185 (2-Chloropyridin-4-yl)methanamine hydrochloride (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor(IC50 : 126 nM).
T7192 Diethyl phosphate Diethyl phosphate, a Non-Specific Metabolite of Organophosphorus Pesticides.
T7199 TPPU TPPU is a potent inhibitor of both human and mouse sEH (IC50 of 3.7 and 2.8 nM, respectively)
T7201 Nelociguat Nelociguat(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.
T7210 Guanosine 5'-diphosphate Guanosine 5'-diphosphate as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T7213 Demecarium bromide Demecarium bromide is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
T7220 Prohydrojasmon Prohydrojasmon is a synthesized plant gowth regulator, which has jasmonic acid activity.
T7222 GS-441524 GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.
T7234 5-Amino-2-chloropyridine 5-Amino-2-chloropyridine is Pyridine intermediates
T7262 Methuosis inducer 1 Methuosis inducer 1 is a potent methuosis inducer, with nticancer activity.
T7263 SMS2-IN-2 SMS2-IN-2 is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic
T7284 Vasopressin acetate (113-79-1(free base)) Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and
T7293 EC330 EC330, a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range.
T7294 Aramchol Aramchol, also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and di
T7295 Miridesap Miridesap is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fl
T7298 FT011 FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.
T7299 beta-estradiol 17-acetate beta-estradiol 17-acetate is a metabolite of estradiol.
T7307 Vorasidenib Vorasidenib is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
T7310 Paquinimod Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
T7312 AX20017 AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis.
T7313 Enclomiphene citrate Enclomiphene citrate is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
T7321 MBP146-78 MBP146-78 is a potent and selective cGMP inhibitor dependent protein kinases.
T7323 BCI-215 BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
T7324 Chelidonine hydrochloride Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities
T7329 C-178 C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
T7331 Ursocholic acid Ursocholic acid, a bile acid found predominantly in bile of mammals.
T7332 trans-2-Decenoic acid Trans-2-Decenoic acid is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees.
T7335 L-2,3-Diaminopropionic acid L-2,3-diaminopropionic acid is an amino acid that is a precursor of antibiotics and staphyloferrin B a siderophore produced by Staphylococcus aureus.
T7343 PF-04979064 PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).
T7344 SDMA SDMA is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).
T7353 RSV604 RSV-604 is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM)
T7355 IC87201 IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
T7357 (S)-b-aminoisobutyric acid (S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine.
T7363 Ibuprofen Piconol Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen
T7366 NGI-1 NGI-1 is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability.
T7379 2-D08 2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
T7386 Bretylium tosylate Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.
T7389 G15 G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM)
T7394 Toceranib Phosphate Toceranib phosphate, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR
T7396 Substance P 1-7 Substance P 1-7 is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalg
T7400 RRX-001 RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity
T7401 (S)-3-AMino-2-Methylpropanoic acid-HCl (S)-3-AMino-2-Methylpropanoic acid-HCl is a chemical compound.
T7402 Meta-Topolin Meta-topolin, a highly active aromatic cytokinin from poplar leaves
T7407 Thyrotropin-Releasing Hormone (TRH), Free Acid Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone lev
T7408 all-trans-4-Oxoretinoic acid All-trans-4-Oxoretinoic acid is an active metabolite of vitamin A.
T7417 Avatrombopag Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
T7421 Melperone Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.
T7431 1,4-Dichlorobenzene 1,4-Dichlorobenzene is a disinfectant, pesticide, and deodorant.
T7432 2'-Hydroxy-2-methoxychalcone 2'-Hydroxy-2-methoxychalcone is a chemical compound.
T7433 2-Phenylethylamine hydrochloride 2-Phenylethylamine hydrochloride acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxid
T7434 Argipressin Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM
T7437 3-(3-Hydroxyphenyl)propionic Acid 3-(3-Hydroxyphenyl)propionic Acid is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.
T7441 Cuminaldehyde Cuminaldehyde is a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity,with a pleasant smell and contr
T7442 4-Isopropylbenzyl Alcohol 4-Isopropylbenzyl alcohol is a natural product,with insecticidal effect.
T7446 Acetophenone Acetophenone is an organic compound used as fragrances
T7448 4-Hydroxyisoleucine 4-Hydroxyisoleucine has antidepressant-like, antidyslipidemic, and antihyperglycemic effects. It displays an insulinotropic activity.
T7450 1-Phenyl-1,2-propanedione 1-Phenyl-1,2-propanedione is a eukaryotic metabolite produced in plant metabolic reactions.
T7452 2-methoxycinnamaldehyde 2-Methoxycinnamaldehyde (2-MCA) is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.
T7453 3-Hydroxycinnamic acid 3-Hydroxycinnamic acid is a natual product isolated from Cinnamomum cassia Presl . 3-Hydroxycinnamic acid has antioxidant activity.
T7456 4-Ethyloctanoic acid 4-Ethyloctanoic acid is a natural product isolated from Saussurea lappa Clarke,acts as food additive,Industrial perfume,and so on.
T7459 Abametapir Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
T7461 2,4-Diamino-6-hydroxypyrimidine 2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis
T7462 2,4-Dichlorophenol 2,4-Dichlorophenol is the precursor to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D).
T7463 2-Hexanone 2-Oxohexane is an ethereal tasting compound. Outside of the human body, 2-Oxohexane is found, on average, in the highest concentration within hyssops and milk (cow).
T7464 3,3-Dimethylglutaric acid 3,3-Dimethylglutaric acid is a compound found in human urine.
T7466 5-Bromocytosine 5-Bromocytosine can be used in the synthesis of cross-link products under anaerobic and aerobic conditions.
T7467 Acid orange 7 Acid orange 7 is a dye used to dye wool.
T7468 α-Terpineol α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB p
T7469 Alendronic Acid Alendronic acid is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
T7470 6-Chloropurine 6-Chloropurine is a building block in chemical synthesis,with Antitumor activities.
T7475 Ademetionine Ademetionine is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
T7476 AS057278 AS057278 is an D-amino acid oxidase (DAAO) inhibitor.
T7477 Argireline Argireline, a synthetic peptide, which is patterned from the N-terminal end of the protein SNAP-25, can both reduce the degree of existing facial wrinkles and demonstrate effective
T7478 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
T7479 Ambroxide Ambroxide is a naturally product,is one of the key constituents of ambergris.
T7480 1-Undecanol 1-Undecanol is a natural product in many foods such as fruits, butter, eggs and cooked pork, is used as a flavoring ingredient.
T7481 2-Hydroxycaprylic acid 2-Hydroxycaprylic acid belongs to the class of organic compounds known as medium-chain fatty acids.
T7483 6-Bromo-2-hydroxy-3-methoxybenzaldehyde 6-Bromo-2-hydroxy-3-methoxybenzaldehyde is an inhibitor of IRE-1α (IC50 : 0.08 μM).
T7485 Methasulfocarb Methasulfocarb is a fungicide, bactericide compound.
T7506 Yoda 1 Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
T7507 γ-L-Glutamyl-L-alanine γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is the substrate of CRF21 (gamma-Glutamylcyclotransferase, GGCT).
T7517 Tiadinil Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles.
T7518 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI Oxidation contributes to antibiotic lethality in stationary-phase mycobacteria.
T7523 Guanidinosuccinic acid Guanidinosuccinic acid (GSA) has been identified as a uremic toxin, is a nitrogenous metabolite isolated in excess from serum and urine.
T7528 3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate 3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate is a chemical compound
T7529 Yamogenin Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.
T7533 Taurolidine Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.
T7534 Teriflunomide Teriflunomide is the principal active metabolite of leflunomide, an approved therapy for rheumatoid arthritis and multiple sclerosis.
T7535 3-Guanidinopropionic Acid 3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-acti
T7536 H-Leu-Leu-Ome.HCl H-Leu-Leu-Ome.HCl is a compound
T7537 Norgestimate Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.
T7538 Tetraethylammonium chloride Tetraethylammonium chloride (TEAC) is a quaternary ammonium compound.
T7544 Fucoidan Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
T7545 6-Aminonicotinamide 6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme.
T7581 voxelotor voxelotor is an inhibitor of sickle hemoglobin (HbS)
T7589 afamelanotide Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.
T7626 Budipine Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
T9115 Vanillic Acid Vanillic acid is used as a condiment in food,which used in wine and vinegar. It is an intermediate in the production of vanillin from ferulic acid.
T9116 N-Succinimidyl 4-(N-maleimidomethyl)cycl N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC), also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker.
T9901 Adalimumab (anti-TNF-alpha) Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
T9906 Ipilimumab (anti-CTLA-4) Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.
T9909 Pertuzumab (anti-HER2) Pertuzumab (anti-HER2), a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2 to bind to other m
T9910 Rituximab (anti-CD20) Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM.
T9912 Trastuzumab (anti-HER2) Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastat
T9913 Ustekinumab Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
T9915 Eculizumab Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
T9916 Alirocumab Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
T9917 Denosumab Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
T9918 Daratumumab Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells.
T9919 Alemtuzumab Alemtuzumab is a humanized monoclonal antibody against CD52, an antigen found on the surface of normal and malignant lymphocytes.
T9920 Evolocumab Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9).
T9924 Obinutuzumab/afutuzumab Obinutuzumab (GA101) a novel glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.
T9925 Ofatumumab Ofatumumab is a fully human monoclonal antibody to CD20, which appears to inhibit early-stage B lymphocyte activation
T9926 Omalizumab Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE)
T9929 Ramucirumab Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T9930 Secukinumab Secukinumab is a fully humanized, monoclonal anti-IL-17A antibody, and the first in its class to be approved by the US Food and Drug Administration for the treatment of moderate to
TCO2745 Cyclic AMP Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect,and it can improve cardiac function of patients and improve
TCP2830 Neryl acetate Used in perfumery and food flavouring.
TCP2934 5-Methyl-2-furaldehyde 5-Methylfurfural has been identified as one of the volatile flavor compounds in tamarind, Dutch Coffee, barrel-aged wines and deep fat-fried soybeans.
TCS0324 2-Pentylfuran Flavouring ingredient.
TCS1554 trans-Benzylideneacetone trans-4-Phenyl-3-buten-2-one is used in various synthetic preparations.
TCS1709 BENZYLACETONE Used in soap perfumes.
TCS1856 2'-Hydroxyacetophenone 2’-Hydroxyacetophenone is a phenolic compound used in the synthesis of potential anti-myobacterial and anticancer agents.
TCS1857 Phenylacetaldehyde Perfumery and flavouring ingredient.
TCS2336 Evodine 1. Evodine has antinociceptive activity.
THS1455 DihydroarteMisinic acid Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
TJO2691 L-(-)-Fucose 1. Anti-infective, anti-cancer, enhance immunity 2. Skin moisturizing and delaying skin aging 3. Nutritional supplement
TJO2729 alanine Alanine is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans, Alanine is one of the most widely used for p
TJO2742 methionine Methionine is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. Methionine is found in meat, fish, and dairy products. It plays an important
TJO2758 D-Glucuronic acid
TJO2795 D-(+)-Galacturonic acid Used in the synthesis of N-(D-galacturonoyl) amino acids and dipeptides.
TJP2872 Acevaltrate 1. Acevaltrate displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1
TJP2891 Maltopentaose Maltopentaose is a maltooligosaccharide that is used for research and diagnostic purposes. They can also be used in nutrients and healthcare.
TJS0123 Arecoline Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (Areca catechu). It i
TJS0311 Ethyl coumarin-3-carboxylate
TJS0312 7-hydroxy-4-methyl-8-nitrocoumarin
TJS0314 4-Methyllimetol 5,7-Dihydroxy-4-methylcoumarin inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property.
TJS0318 6-Hydroxy-4-methylcoumarin Growth inhibition of human U937 cells by [3H]thymidine incorporation assay
TJS0339 Coumarin-3-carboxylic acid The combination of Valproic acid with coumarin-3-carboxylic acid suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways
TJS0341 7-Amino-4-(trifluoromethyl)coumarin 7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist.
TJS0368 7,8-Dihydroxy-4-phenylcoumarin 7,8-Dihydroxy-4-phenylcoumarin inhibits the activity of Staphylococcus aureus DNA helicase
TJS0405 Lucidin 1. Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.
TJS0851 Plantagoside Plantagoside is a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50: 5 μM). It also is a potent inhibitor of the Maillard reaction.
TJS0856 Dalbergin 1. Dalbergin exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin preve
TJS0928 Calenduloside E Calenduloside E exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by inhibiting glucose transport at the brush bor
TJS1159 Chrysosptertin B 1. Chrysosplenetin is a metabolic inhibitor of artemisinin.
TJS1183 Cyclen Cyclen is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.
TJS1942 Siegesmethyetheric acid
TL0001 dencichine Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic sy
TL0002 Liquiritin apioside Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia.
TL0004 FERULIC ACID METHYL ESTER Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activiti
TL0005 (-)-3,5-Dicaffeoyl quinic acid 3,5-Dicaffeoylquinic acid is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giar
TL0009 coniferin Coniferin has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin anal
TMA0835 Deapi-platycodin D3 Deapi-platycodin D3 is a natural product isolate from the root of Platycodon grandiflorum.
TMA0958 Arenarioside Arenarioside is a natural product, and GI50 values of 10-16 microM against B16F10 cell.
TMA1603 Parishin C Parishin C is a phenolic glycoside and a major component of G. elata, have antioxidant property
TMA2394 DL-α-Tocopherol Antioxidant.
TMA2440 5'-UMP disodium salt Uridine 5′-monophosphate disodium salt has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used t
TMM2618 Gibberllin A7 Gibberillic acids (GA) are important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division a
TMO2681 Xanthosine Inhibition of inosine and alanine-induced germination of Bacillus anthracis Sterne spore pre-incubated for 15 mins.
TMO2752 5'-Cytidylic acid A constituent of nucleic acids. It was isolated from yeast nucleic acid.
TMO2787 Anthraquinone Anthraquinones are the main active constituents in herbs often used to relieve constipation.
TMO2790 1-Naphthaleneacetic acid 1-Naphthaleneacetic Acid, is widely used in agriculture for various purposes. It is a synthetic plant hormone in the auxin family and is an ingredient in many commercial plant root
TMS0418 Dihydroergotoxine mesylate It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
TMS0484 (-)-Syringaresinol 4-O-β-D-glucopyranosi 1. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemotherapeutic agent for th
TMS0719 Sequoyitol Sequoyitol, a methyl derivative of inositol, is often used to treat diabetes.
TMS1830 5'-IMP disodium salt A flavor agent.
TMS2171 Naringenin Naringenin is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promote
TMS2179 Zeatin Zeatin is a cytokinin derived from adenine. Zeatin was discovered in immature corn kernels from the genus Zea. It promotes growth of lateral buds and when sprayed on meristems stim
TMS2181 trans-Zeatin Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
TMS2182 Trans-Zeatin Riboside Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow
TMS2262 (-)-CAMPHOR (1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one also known by its common name as (-)-Camphor is a chiral intermediate of camphor and is used as a flavour additive in foods and sw
TWA2417 Sodium taurocholate hydrate Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic a
TWO2659 Benzaldehyde intermediate.
TWO2724 N,N-Bis(2-hydroxyethyl)-p-phenylenediami
TWO2727 Tripalmitin Tripalmitin is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a diet
TWO2759 Thymine One of the pyrimidine bases of living matter. Derivation: Hydrolysis of deoxyribonucleic acid, from methylcyanoacetylurea by catalytic reduction. Use: Biochemical research. Thymine
TWO2771 2-Adamantanol 2-Adamantanol was used to synthesize antiallergic drug Mizolastine.
TWP2911 Thymidine 1. Thymidine overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
TWS0414 Cannabidiol Cannabidiol is GPR55 and weak CB1 antagonist (IC50s: 0.445 and 3.35 μM), CB2 receptor inverse agonist and inhibitor of anandamide uptake (IC50: 27.5 μM). It also a weak agonist a
TWS0902 gypenoside A anticancer
TWS1229 Aristolone Aristolone has potential anti-cancer activity.
TWS1293 Angelic anhydride Angelic Anhydride is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from
TWS1563 Incensole 1. Incensole has a protective or stimulating effect on β-cells of the rat pancreas, it also can increase the insulin secretion, which evidenced by a significant increase both in b
TWS1613 mulberroside B Antitussive, antiasthmatic, hypoglycemic, anti - tumor, treatment of gout.
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