||Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, w
||Iron(II) fumarate, also named as ferrous fumarate, is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake.
||Sodium Nitroprusside is a potent vasodilator, releasing in blood with no spontaneously.
||Methylene Blue trihydrate
||Methylene blue is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene b
||Mercaptopurine is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, u
||Phenethyl alcohol is an antimicrobial, antiseptic, and disinfectant. It is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
||Mecarbinate is arbidol hydrochloride's chemical intermediate.
||Anethole is a type of aromatic compound that exists widely in nature, widely utilized as a seasoning substance.
||Mephenesin is a centrally acting muscle relaxant with a short duration of action.
||Mexenone is a benzophenone-derived sun protection.
||Phenolphthalein is an acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.
||Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the formation of secon
||It is an inhibitor of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)
||Valethamate bromide is an anticholinergic agent.
||Ethylhexyl salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester f
||Agent for improving learning or memory [US6803366]Gamma Hydroxybutyric Acid, commonly abbreviated GHB, is an illegal therapeutic drug in multiple countries. In the US， it is curr
||Xylose is a sugar first derived from wood. Xylose is classified as a monosaccharide of the aldopentose type.
||Halazone is fine white powder with an odor of chlorine.
||Octodrine is a stimulant drug,a platinum complex form of which was also investigated as a possible anti-tumor drug.
||Oxeladin is a highly potent and effective cough suppressant,which can treat all types of cough of various etiologies. It is not related to opium or its derivatives, so treatment wi
||Dichlorophen is a nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ing
||Oxiniacic Acid is a nicotinic acid derivative, used to treat hyperlipoidemia.
||Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use i
||Homosalate is an organic compound used as a chemical UV filter. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol.
||Octinoxate is an organic compound that is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage,primarily as an ingredient in
||Dantrolene sodium salt
||Dantrolene is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neuromuscu
||Cepharanthine， a biscoclaurine alkaloid， suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and i
||Ftaxilide has antibacterial property, used as antiseptic.
||Folinic Acid Calcium Salt Pentahydrate
||Folinic Acid, a reduced folic acid, is used in combination with other chemotherapeutics.
||Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.
||Fosfomycin calcium is an antibiotic, used for the treatment of urinary tract infections and intestinal infections caused by susceptible strains.
||It is used as a stimulant-laxative, treating constipation by inducing bowel movements. The compound is present in what is commonly referred to as the aloe latex that exudes from
||Ticagrelor, produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved f
||Pramiracetam, derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Prami
||Amorolfine Hydrochloride is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually dis
||Levetiracetam is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levetiracetam has been li
||Secnidazole is a second-generation 5-nitroimidazole antimicrobial that is structurally related to other 5-nitroimidazoles including [DB00916] and [DB00911], but displays improved o
||Ceftiofur sodium, an antibiotic of the cephalosporin type (third generation), is used as veterinary medicine.
||Thioctic acid is an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC
||Meropenem is a carbapenem antibiotic with broad spectrum of activity that is administered intravenously and used for severe bacterial infections due to sensitive agents. Meropenem
||Bromisoval is a mild hypnotic and sedative with potential toxicity.
||Etamivan (INN) or ethamivan (USAN), is a respiratory stimulant drug concerned with nikethamide. Its trade name is Analepticon, and no longer used in the US.
||Closantel, a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.
||2-(Acetyloxy)-3-Methylbenzoic Acid is used in qHTS Assay for Inhibitors of hydroxysteroid (17-beta) dehydrogenase 4, HSD17B4 with activity value of 19.95 µM
||Lonidamine is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).
||Trimetozine is a sedative that has been marketed in Europe since 1959. It has mild tranquilizing effects and has been used to treat anxiety.
||Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.
||Gemcitabine is a DNA synthesis inhibitor that can inhibit the growth of MIAPaCa2, BxPC3 and Capan2 cells (IC50s: 40/18/12 nM). It can also induce autophagy.
||Mepiroxol, an antihyperlipidemic, is also called 3-PYRIDINEMETHANOL N-OXIDE.
||Carsalam is a nonsteroidal anti-inflammatory drug.
||Chromocarb is a vascular protective agent used to treat venous disorders and microvascular affections.
||Merbromin is an organomercuric disodium salt compound and a fluorescein, used as a topical antiseptic for minor cuts and scrapes.
||Iodipamide is a water-soluble radiographic contrast media for intravenous cholangiography and cholecystography.
||Mefexamide hydrochloride is a central stimulant.
||Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity.
||Escin is biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of Aesculus.
||Meclocycline sulfosalicylate salt
||Meclocycline (INN), a tetracycline antibiotic, is used topically (i.e. for skin infections) as it is totally insoluble in water and may damage kidney and liver if given systemicall
||Sulfogaiacol is an antitussive agent, used for acute respiratory tract infections and cough.
||Bephenium hydroxynaphthoate is a B-type AChR activator, formerly used in the treatment of hookworm infections and ascariasis.
||Procodazole is a non-specific active immunoprotective agent against viral and bacterial infections.
||9-Aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used
||Orbifloxacin is a broad-spectrum fluoroquinolone antibiotic.
||Metyrapone is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
||Pempidine is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.
||Lactitol monohydrate is a disaccharide analog of lactulose. It has been widely used to treat constipation & hepatic encephalopathy.
||Undecylenic Acid is a natural or synthetic fungistatic fatty acid, with antifungal activity.
||Tyloxapol is a non-ionic liquid polymer used as a surfactant.
||Etidronic is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
||Actarit is an anti-inflammatory drug.
||Diathesin is an intermediate for medicine, perfume, pesticide.
||Blutene chloride, a phenothiazine, is used as a biological stain, a hemostatic, and a dye for silk and wool. Blutene chloride is also used as a diagnostic aid for gastric neoplasms
||Acedoben (4-acetamidobenzoic acid) is the acetyl derivative of para-aminobenzoic acid (PABA).
||Citiolone, a drug used in liver treatment, is a derivative of the amino acid cysteine.
||Oxantel pamoate is used as an Antinematodal agent.
||Diperodon is a local anaesthetics.
||Hexetidine is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.
||Sorbitol is a polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diur
||Benzalkonium chloride is a cationic surface-acting agent containing the quaternary ammonium group. It has three main categories of use: as a cationic surfactant, a biocide, and pha
||Bisoctrizole is a benzotriazole-based organic compound that is added to sunscreens to absorb UV rays.
||Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti
||Miconazole nitrate, an imidazole antifungal agent, selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalia
||Camylofin is an antimuscarinic, used for relaxing smooth muscle.
||Phenol Red is a pH indicator, red dye, and diagnostic aid for measurement of renal function. It is used also for researches of the gastrointestinal and other systems.
||Dibenzothiophene, a component of petroleum oils, is a sulfur-containing polycyclic aromatic hydrocarbon (PAH) derivate consisting of 3 fused rings with keratolytic activity.
||Valpromide is a carboxamide derivative of valproic acid, used in the treatment of epilepsy and some affective disorders.
||Nitromide is an anti-parasitic drug.
||2-Aminoheptane is used for proteomics research.
||Morantel tartrate is an antinematodal agent used mainly for livestock.
||Fluocinolone acetonide is a glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has
||Cinepazide maleate, a maleate salt form of cinepazide, is a vasodilator.
||Crotamiton is an antipruritic and a scabicidal agent available as a lotion or cream for topical use only. It is a colorless to slightly yellowish oil with a faint amine-like odor.
||Clofazimine is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against va
||Risedronic acid (Risedronate ), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
||Eprodisate Disodium is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
||Aklomide is used in poultry to treat parasites.
||Artemisinin is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chlor
||Pyrantel tartrate is broad spectrum anthelmintic for livestock.
||Pipemidic acid, a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.
||Carzenide is an organic synthesis intermediate.
||Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular
||Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.
||Octocrylene is used as an ingredient in sunscreens and cosmetics. This organic compound can penetrate into the skin where it acts as a photosensitizer. This results in an increased
||Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where i
||Dehydrocholic acid is a synthetic bile acid, produced by the oxidation of cholic acid.
||Phthalylsulfacetamide is a sulfonamide antibiotic used for topical application to the skin and the conjunctiva.
||Calcium gluconate is the calcium salt of gluconic acid, used as a calcium replenisher in hypocalcemic states.
||Cinromide is used as a novel anticonvulsant agent.
||Guanidine hydrochloride is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is
||Sodium Gluconate is the sodium salt of gluconic acid with a chelating property.
||Pentetic Acid is an edetate and a chelating agent used in preparing radiopharmaceuticals.
||Talc is a mineral composed of hydrated magnesium silicate.
||Edetate Trisodiumis used to bind metal ions in the chelation therapy.
||Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Supplemental glucosamine may help to rebuild cartilage and
||Imidazolidinyl urea is an antimicrobial preservative used in cosmetics.
||Diclofenac Diethylamine， a non-selective COX inhibitor， is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
||Glucuronolactone is a naturally occurring chemical that is an important structural component of nearly all connective tissues. Glucuronolactone is also found in many plant gums.
||Sulfinpyrazone is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
||Proflavine Hemisulfate is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging
||Bucetin is a pharmaceutical drug that acts as an analgesic and antipyretic. Bucetin was withdrawn from use in 1986 due to renal toxicity.
||Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti
||Dropropizine, a racemic non-opiate antitussive agent, is served as a cough suppressant.
||Florfenicol is a fluorinated synthetic analog of thiamphenicol. In the United States, florfenicol is currently used to treat bovine respiratory disease (BRD) associated with Mannhe
||Florfenicol, a fluorinated synthetic analog of thiamphenicol, is currently indicated for the therapy of bovine respiratory disease (BRD) associated with Mannheimia (Pasteurella) ha
||Berberine hydrochloride is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used ora
||Pentoxyverine Citrate, an antitussive (cough suppressant), is frequently used for a cough related to illnesses like the common cold.
||Decoquinate is a coccidiostat for poultry.
||Ethylvanillin is a flavorant used in the production of chocolate. It is about three times as potent as vanillin.
||Dimethyl fumarate, a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
||Aminothiazole, a thyroid inhibitor，displays antibacterial activity.
||Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
||Cetrimonium Bromide is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.
||Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
||Capitrol is a synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes
||Leucobasal is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its ef
||Meglumine, a derivative of sorbitol, is used in conjunction with iodinated organic compounds as contrast medium.
||L-Pyroglutamic acid, a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism.
||Cloxyquin is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.
||Diiodohydroxyquinoline, a topical therapeutic agent, has satisfactory antibacterial properties.
||Pancreatin is a mixture of several digestive enzymes secreted by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease.
||Euquinine generally is served as the febrifuge, antimalarial, and tonic.
||2-Amino-5-nitrobenzophenone is used as industrial and organic intermediate.
||2,3,4-Trimethoxybenzaldehyde is used as medicine intermediate.
||4-Fluoroanisole is a intermediates in medicine, pesticide, liquid crystal materials.
||Dulcitol is a sugar alcohol that is a metabolic breakdown product of galactose.
||Flavanones from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flava
||Intermediate of Pregabalin
||Intermediate of Pregabalin.
||1-Aminopiperidine is a metabolite (M1) of the canabinoid receptor 1 antagonist Rimonabant, an antiobesity agent.
||Bis(4-cyanophenyl)methanol is a metabolite of Letrozole.
||Memantine Related Compound B
||Memantine impurity B is an impurity of Memantine.
||Cyclopropyl cyanide is the minimum carbon ring molecule with a cyanide group attached. It has mainly used in experiments with microwave spectroscopy, photodissociation, and rotatio
||Desbenzyl Donepezil Hydrochloride
||Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil.
||3-Methyl-2-oxindole is a reactant for O-acetylation reactions, enantioselective α-amination reactions and for aldol reactions with glyoxal derivatives and more.
||Dihydrocaffeic Acid is a natural product containing a catechol group with an α,β-unsaturated carboxylic acid chain. Dihydrocaffeic Acid has been shown to have hepatoprotective ac
||Dibenzosuberol, an organic compound, is used as a Pharmaceutical intermediate.
||Fluoronaphthalene is incompatible with strong oxidizing agents.
||Homoisovanillic acid is used as pharmaceutical intermediates.
||Dichlorodiphenylmethane is used as pharmaceutical intermediates.
||1-(2-Hydroxyethyl)imidazolidine-2-thione is used as pharmaceutical intermediates.
||Trimethylacetic anhydride is used as medical intermediate
||FlutaMide Related CoMpound B
||FlutaMide Related CoMpound B is used as pharmaceutical intermediates.
||Methyl 5-methylnicotinate is used as pharmaceutical intermediates.
||4'-tert-Butylacetophenone is used as medical intermediate
||Domperidone EP Impurity A
||Domperidone EP Impurity A is used as pharmaceutical intermediates.
||D-Ornithine monohydrochloride is used as pharmaceutical intermediates.
||Isonicotinamide is used as pharmaceutical intermediate to synthesis Cefalonium, etc.
||4-Hydroxyisophthalic acid is used as medical intermediate
||Dibutylurea is used as pharmaceutical intermediates.
||4-Diethylamino-2-butyn-1-ol is used as pharmaceutical intermediates.
||6-Methoxy-2-naphthoic acid is an modulator of NMDAR.
||3-(Methylamino)toluene is used as dye intermediates
||Hydroferulic acid is used as the intermediates of perfume and essence.
||Dibenzosuberone, pharmaceutical intermediates, is used for the synthesis of drug amitriptyline.
||3,3-Diphenylpropylamine is used for synthetic drugs Mepramidil
||2-Methoxy-5-sulfamoylbenzoic Acid is a metabolite of the antipsychotic drug, Sulpiride.
||Protocatechuic acid (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protec
||Homoveratronitrile is an impurity of Verapamil. It is also an intermediate in the preparation of the muscle relaxant Papverine.
||1-Indanone is the intermediate od Indinavir.
||Bis(2-chloroethyl)amine hydrochloride is used as pharmaceutical intermediate.
||2-Methylbenzhydrol is used as pharmaceutical intermediates.
||5-Chloroanthranilic Acid is a metabolite of the pesticide Chlordimeform. It can be used in the preparation of disease-modifying antirheumatic drugs (DMARDs).
||Homoveratrumic acid is the papaverine intermediate, used to synthesis cardiovascular drugs.
||Pyrazinoic acid is the intermediate of pyrazole thiamethoxam sulfur.
||3,5-Dihydroxybenzoic Acid is a metabolite of alkylresorcinol in human urine and plasma. It is also used as a biomarker of whole grain wheat and rye.
||2-Methylbenzene-1-sulfonamide is used for saccharin, pharmaceutical intermediates, etc.
||Methyl EudesMate is the intermediate of antibacterial efficiency medicine trimethoprim.
||2-Methoxynaphthalene is served as Odor agents.
||Diphenyl sulfide is used as pesticide, medicine, dye intermediates.
||1-Methylimidazole is a metabolite of 1-methyl-2-thioimidazole (methimazole) which inhibits bone resorption.
||Diethylaminoethoxyethanol is served in the production of cough medicine Toclase and so on.
||Chlorobenzothiazolinone inhibits recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay with activity va
||Iodeosin, a tetraiodofluorescein, is used as a red coloring in some foods (cherries, fish), as a stain of some cell types, and as a disclosure of DENTAL PLAQUE. Its molecular struc
||4-Pentynoic acid has been used in reactions with 1-bromo-1-alkynes in the presence of a Pd catalyst yields biologically active ynenol lactones. It also is used in a synthesis of a
||Isomaltose is a reducing disaccharide, similar to maltose, but with an α-(1-6)-linkage instead of the α-(1-4)-linkage.
||Fructooligosaccharides is a levorotatory monosaccharide and an isomer of glucose.
||Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
||Maltose is a dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing.
||D-(+)-Maltose monohydrate, a dextrodisaccharide from starch and malt, is used as a fermentable intermediate and sweetening agent in brewing.
||Maltitol is a sugar alcohol (polyol) used as a sugar substitute.
||Lactose is a disaccharide derived from galactose and glucose that is found in milk.
||Arabinose is an aldopentose, including an aldehyde (CHO) functional group.
||Xylitol is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.
||D-Galactose is an aldohexose that exists naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metaboli
||Mannose is a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants.
||5-Phenylhydantoin is a metabolite of Mephenytoin. 5-Phenylhydantoin has been shown to bind to voltage-dependent sodium channels (NVSC) and has anti-epileptic properties.
||Iminostilbene (Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain.
||N-Methyl-N-(trimethylsilyl)trifluoroacetamide is a metabolite of Famprofazone in humans.
||10,11-Dihydrocarbamazepine is used as pharmaceutical intermediates.
||Phthalic Acid Monobenzyl Ester
||Monobenzyl Phthalate is Phthalate metabolite.
||Desalkylterbuthylazine is used as pharmaceutical intermediates.
||Monobutyl Phthalate is a di-n-Butylphthalate (DBP) metabolite.
||Dihydroartemisinin is a metabolite of artemisinin.
||Heptachlor-endo-epoxide is a degradation product of heptachlor that occurs in soil and in or on crops when treatments with heptachlor, an insecticide, have been made. Forms readily
||Azobenzene is a compound constituted of two phenyl rings linked by an N=N double bond. Azobenzene is the simplest example of an aryl azo chemical compound. The term 'azobenzene' or
||4-Hydroxy-3-methoxymandelic acid is a chemical intermediate.
||DL-6-Methoxy-Alpha-Methyl-2-Naphthalenemethanol is used as pharmaceutical intermediates.
||Used as medical intermediates
||4-Amino-5-chloro-2-methoxybenzoic Acid (Metoclopramide EP Impurity C) is a Metoclopramide metabolite.
||1-(3-Chlorophenyl)piperazine hydrochloride is used for the synthesis of trazodone, Etoperidone, Nefazodone, etc.
||Diphenyl oxide is used in the manufacture of spices and dyes.
||2-Chlorophenothiazine is used as the intermediate of Chlorpromazine hydrochloride.
||Diphenylacetonitrile is used as herbicide and industrial intermediate.
||4-Hydroxybenzophenone is used as an intermediate of infertility drugs Clomifene.
||Iminodibenzyl is used for the intermediates of antiepileptic drug carbamazepine.
||Atropic acid (Ipratropium EP Impurity D) is an impurity of Ipratropium bromide and Atropine Sulfate.
||Ethyleneurea is used as a formaldehyde scavenger and intermediate.
||2-Phenylbutyric Acid is used as an industrial intermediate.
||Gallic acid trimethyl ether
||Gallic acid trimethyl ether are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in
||(2-Chlorophenyl)phenyl-methanone is used as pharmaceutical intermediate.
||2-Acetyl-4-butyramidophenol is gray crystalline powder.
||p-(2-Methoxyethyl) phenol, an important kind of pharmaceutical intermediates, is primarily used in the synthesis of metoprolol which is effective drugs in the therapy of cardiovasc
||4-Methylmorpholine N-oxideis an organic compound, used in organic chemistry as a co-oxidant and sacrificial catalyst in oxidation reactions.
||2-Acetyl-6-methoxynaphthalene, the key intermediate of naphthalene tome and naproxen, is used in synthetic non-steroidal anti-inflammatory analgesic medicine and.
||2-Methyl-5-nitroimidazole is a kind of small molecular compounds.
||Butyl benzyl phthalate
||Butyl benzyl phthalate is used as a plasticizer for PVC.
||Diclofenac Amide is used as a intermediates of Diclofenac.
||3-Amino-5-methylisoxazole is pharmaceutical intermediates, used in the production of sulfonamide drugs.
||N-(1-Adamantyl)acetamide is used as intermediates for synthesis of amantadine hydrochloride.
||Phenyl acetate, the ester of a phenol and acetic acid, can be produced by reacting acetic anhydride with phenol. Another way is produced by decarboxylation of aspirin.
||Tris(2-chloroethyl) phosphate is served as flame retardants.
||3,4-Dimethoxybenzyl Alcohol is an organic compound.
||2-Pyridineethanol is used as an industrial chemistry intermediate.
||Bispyrazolone is light yellow or white crystalline powder.
||Dimethylsulfamoyl Chloride is a kind of small molecular compound.
||2-Hydroxybenzimidazole is used as an intermediate in industry.
||Nicotinic acid hydrazide
||Nicotinic acid hydrazide is a small molecular compound.
||Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most
||4-Chlorosalicylic acid is antimicrobial compositions comprising a metal salt and a benzoic acid analog.
||Flecainide Impurity D
||Flecainide Impurity D is used as an intermediate in industry.
||1-Aminohydantoin hydrochloride is an organic compound.
||Chloramine-T is a N-chlorinated, and N-deprotonated sulfonamide, used as a biocide and a mild disinfectant.
||2-Naphthol is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring.
||Orlistat is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.
||Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy
||Sulisobenzone (benzophenone-4), an ingredient in certain sunblocks, protects the skin against damage by short-wave UVA ultraviolet light and UVB.
||Niflumic acid is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.
||Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or in
||Avobenzone, an oil-soluble ingredient, is a dibenzoylmethane derivative used in sunscreen products to absorb the full spectrum of UVA rays.
||Aspartame, an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester.
||Dioxybenzone (benzophenone-8) is a derivative of benzophenone, used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.
||Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
||Broxyquinoline is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes.
||L-cycloserine irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of ga
||Chlormezanone is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
||Tetrabenazine is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles
||Piroctone olamine is a compound sometimes used in the treatment of fungal infections. Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone.
||Ursolic acid(Bungeolic acid), a natural pentacyclic triterpenoid carboxylic acid, shows anti-tumor effects.
||Formononetin is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
||Piperonyl butoxide is an insecticide synergist, particularly for rotenone and pyrethroids.
||Benzyl benzoate is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe it
||Triacetin is a triglyceride that is used as an antifungal agent.
||Urea is formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end metabolite of protein catabolism and accounts for about one-half of the
||Guaifenesin is an expectorant that also has some muscle relaxing action. It is used in many cough preparations.
||Sulfamethazine is a sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
||DL-Carnitine is the constituent of liver and striated muscle. In therapeutically It is used to stimulate pancreatic and gastric secretions and to treat hyperlipoproteinemias.
||10-Undecenoic acid zinc salt, a synthetic or natural fungistatic fatty acid, is used topically in creams against eczemas, fungal infections, ringworm, and other cutaneous condition
||Carglumic acid is an orphan drug used to treat hyperammonemia in patients with N-acetyl glutamate synthase absence. This rare hereditary disease results in elevated blood levels of
||Ethoxyquin is an antioxidant used in animal feeds.
||Anethole (anise camphor), an organic compound, is widely served as a condiment substance. It is a derivative of phenylpropene, a type of aromatic compound that exists widely in ess
||Diolane, colorless liquid, is a chiral diol. It is an industrial compound produced from diacetone alcohol by hydrogenation.
||Oxolamine is a cough suppressant that is able to be used as a generic drug in many jurisdictions.
||Carbadox is an antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibit
||Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions
||Troxerutin, a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.
||Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia hae
||An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is
||Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.
||Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion o
||Lactulose ,a synthetic disaccharide ,is used in the treatment of constipation and hepatic encephalopathy.
||Tannic acid is a novel hERG channel blocker.
||Acetrizoic acid is the first monomeric ionic compound used as an X-ray contrast agent.
||2,2,2-Tribromoethanol is an organic compound used to anesthetize mice.
||Spiramycin is a macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is u
||Lipoamide is a trivial name for 6,8-dithiooctanoic amide. It is 6,8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an
||Cefsulodin sodium salt hydrate is a β lactam antibiotic.
||Bromhexine hydrochloride is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
||Etofylline is used for difficulty in breathing, asthma, breathing difficulty and other conditions.
||Benzoic acid is a fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid.
||Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
||Sulfamethoxypyridazine is a sulfanilamide antibacterial agent.
||Cyromazine is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.
||Primaquine Phosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclea
||Carbazochrome sodium sulfonate
||Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for the treatment of hemorrhoids.
||Mefloquine is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
||Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry.
||Amprolium is a coccidiostat that interferes with thiamine metabolism.
||Dinitolmide, a poultry feed additive, is a coccidiostat for poultry.
||Dimetridazole is a drug that combats protozoan infections. It is a nitroimidazole class drug. It has been banned by the Canadian government as a livestock feed additive.
||Acetylcysteine is the N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effect
||Clioquinol is an orally bioavailable, lipophilic, copper-binding, halogenated 8-hydroxyquinoline with antifungal, antiparasitic and potential antitumor activities.
||Ursolic acid (UA), a pentacyclic triterpene acid, is used in anticancer chemotherapies.
||Aminocaproic acid is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
||Sulfamethoxazole is a Sulfonamide Antimicrobial. The mechanism of action of sulfamethoxazole is as a Cytochrome P450 2C9 Inhibitor. The chemical classification of sulfamethoxazole
||D(+)-Glucose is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeuti
||Flavoring agent and non-nutritive sweetener.
||Sulfapyridine is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.
||Furaltadone hydrochloride is an antibacterial and shows distinct curative effect in the treatment of coccidiosis.
||Chloroxylenol (4-chloro-3,5-dimethylphenol), a broad spectrum antimicrobial chemical compound, is used to control virus, bacteria, fungi, and algae. It is used in households and ho
||Dehydroacetic acid, a pyrone derivative, is served frequently as a fungicide and bactericide.
||Cetylpyridinium chloride monohydrate
||Cetylpyridinium chloride (CPC), a cationic quaternary ammonium compound, is used in certain classes of throat sprays, mouthwashes, lozenges, toothpaste, nasal sprays, and breath sp
||Chlorobutanol is a chemical preservative, sedative hypnotic and weak local anaesthetic similar in nature to chloral hydrate. It has antibacterial and antifungal properties. Chlorob
||Chlorquinaldol is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity.
||Terpin hydrate, a cis-form hydrate, is derived from sources such as oil of turpentine, oregano, thyme, and eucalyptus. It is used as an insect repellent and expectorant. Terpin hyd
||Tetracycline is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
||METACETAMOL is an organic compound.
||Sulfa drugs, used in the treatment of avian coccidiosis.
||Tamoxifen is an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM).
||Sulfabenzamide is a sulfonamide antibacterial agent used alone or with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation.
||Zoxazolamine is a uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.
||Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
||Allantoin, a urea hydantoin found in urine and plants, is used in dermatological preparations.
||Azelaic acid is bactericidal against Propionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of microbial cellular proteins. Azelaic Ac
||Butylparaben is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.
||Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure
||Acesulfame potassium is a non-nutritive sweetener.
||Cyclamic acid is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogeni
||Tranexamic acid is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.
||Cefazolin sodium salt
||Cefazolin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin Sodium is the sodium salt of cefazolin, a b
||Oxyclozanide is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.
||Avermectin B1 (Abamectin) is served as anthelmintic and insecticide.
||Ethopabate is an inhibitor of folate metabolism, used as a coccidiostat in poultry.
||Iopanoic acid is an iodine-containing radiocontrast medium used in cholecystography.
||Trometamol is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inf
||Teicoplanin is a semisynthetic glycopeptide antibiotic, used to treat Gram-positive bacteria.
||Doramectin is an antiparasitic agent.
||Medrysone is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellu
||Artamine, possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artam
||DL-Penicillamine is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used o
||Oxacillin sodium is an antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.
||7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
||Dicloxacillin NaOH is a narrow-spectrum β-Lactam antibiotic of the penicillin class, used to treat infections caused by susceptible Gram-positive bacteria.
||Tylosin is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
||6-Benzylaminopurine, benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit ric
||Amoxicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Amoxicillin Anhydrous is the anhydrous form of a b
||Lupetidin is a neuropathic blocker, with antihypertensive effect.
||Flurothyl is a convulsant used in experimental animals.
||Cefoxitin sodium is a semisynthetic cephamycin antibiotic resistant to beta-lactamase.
||Moxonidine is a selective agonist at the imidazoline receptor subtype 1， acting as an antihypertensive drug.
||Cloxacillin sodium monohydrate
||Cloxacillin Sodium is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
||Monensin sodium salt
||Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.
||Docetaxel is a microtubule inhibitor that inhibits microtubule disassembly (IC50: 0.2 μM).
||Hesperidin is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
||Netilmicin Sulfate is an aminoglycoside antibiotic.
||Doripenem Hydrate is a broad-spectrum injectable antibiotic, used for Gram-positive, Gram-negative and anaerobic pathogens.
||Risedronate sodium is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatment of OSTEOPOROSIS.
||Clopidol is a very effective anticoccidial agent used in poultry.
||Mebeverine hydrochloride, a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gut.
||Vitamin A Palmitate is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.
||Toltrazuril, an antiprotozoal agent, has effect on Coccidia parasites.
||Ticarcillin Disodium is the disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Simil
||Amphotericin B is an antifungal agent with a broad spectrum of activity against many fungal species.
||Anthralin is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS
||Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of eff
||Vitamin K1 a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.
||Sulfadimethoxine is a sulfanilamide that is used as an anti-infective agent.
||Cysteamine is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
||Benzyl isothiocyanate (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atheroscler
||Chlorthalidone is a benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.
||Denatonium, a quaternary ammonium cation, is a compound of a salt with an inert anion like saccharide or benzoate. Its structure is involved in the local anesthetic lidocaine which
||Polymyxin B sulfate
||Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic deterge
||Minocycline is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline ca
||Sarafloxacin hydrochloride, a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.
||Nithiamide is an orally available antiprotozoan agent used in the treatment of vaginal trichomoniasis.
||Zucapsaicin is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeut
||Enilconazole is an Agricultural fungicide Enilconazole is a fungicide widely used in agriculture, particularly in the growing of citrus fruits. It is also called Imazalil, Chlorami
||Ciclopirox Olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
||Penicillin V potassium salt
||Penicillin V potassium is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.
||Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1)， used as an antioxidant dietary supplement.
||Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria，used in the treatment of upper and lower respiratory tract infections.
||Diastase is any one of a group of enzymes which catalyses the breakdown of starch into maltose.
||Clorsulon is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
||Taurocholic acid sodium salt hydrate
||Taurocholic acid sodium salt hydrate is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredient of the bile of carnivorous animals, is used as
||Fenbendazole is an antinematodal benzimidazole used in veterinary medicine.
||Diminazene is a trypanocidal agent.
||Menbutone is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly
||Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
||Fusidine is an antibiotic isolated from the fermentation broth of Fusidium coccineum.
||Protionamide is a thioamide derivative with antitubercular activity.
||Acipimox is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insuli
||Moguisteine is a new-type peripheral non-narcotic antitussive drug.
||Diclazuril is a coccidiostat.
||Bifonazole acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called erg
||Protoporphyrin IX is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll.
||Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citic
||Ribostamycin, an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome.
||Sisomicin Sulfate is the sulfate salt form of sisomicin, a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is structurally similar to gen
||A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including
||Ceftriaxone sodium salt is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
||Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal
||Bacitracin, a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.
||Cepazine is a second generation oral cephalosporin antibiotic.
||Pamabrom is a diuretic, used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with the premenstrual and menstrual periods.
||Beclamide (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was st
||Dicloralurea is a veterinary food additive that inhibits methane production in herbicide ruminants.
||4-(Aminomethyl)benzoic acid, an antifibrinolytic, is an unnatural amino acid derivative.
||Chlorindanol is a new antiseptic agent.
||Chlorophyllin sodium copper salt is a semi-synthetic mixture of water-soluble sodium copper salts derived from chlorophyll, primarily used as a food additive and alternative medici
||Ubenimex competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory a
||Pyrantel pamoate is a depolarizing neuromuscular blocking agent.
||Cromolyn sodium is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.
||Levonorgestrel is a Progestin and Progestin-containing Intrauterine Device. The physiologic effect of levonorgestrel is by means of Inhibit Ovum Fertilization.
||Dixanthogen is an ectoparasiticide.
||Anethole trithione is a bile secretion-stimulating drug that restores salivation and relieves the discomfort of dry mouth in chemotherapy-induced xerostomia.
||Vincamine is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorder
||Fusidate Sodium is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infecti
||Oxiconazole Nitrate is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fu
||Eugenol is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity.
||Roniacol is an alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and th
||Guaiacol is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can b
||Auranofin is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness.
||4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.
||Cinchonidine is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
||Diatrizoate Sodium is an iodinated radiopaque X-ray contrast medium. Diatrizoate sodium blocks X-rays, thereby allowing body structures containing iodine to be delineated in contra
||Artemether is an antimalarial agent used to treat acute uncomplicated malaria.
||Pamidronate disodium salt
||Pamidronate disodium, a nitrogen-containing bisphosphonate, can help to strengthen bones.
||Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
||N-Carbethoxy-4-piperidone is an aminopyrimidine derivative, compositions containing them and there served as pharmaceuticals.
||3-Chloropropiophenone is a small molecular compound.
||Leucocrystal violet is a triphenylmethane dye.
||4-Chloro-4’-hydroxybenzophenone is an organic compound.
||1,1-Bis(Methylthio)-2-Nitroethylene is an organic compound.
||1-Phenyl-1,2-ethanediol is O-benzyl oxime ether derivatives and used as pesticides.
||2-Aminobenzothiazole is an organic compound.
||Paint additives and coating additives not described by other categories
||5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucle
||4-Butoxyphenol is an organic compound.
||Adenosine 5'-triphosphate disodium salt
||Adenosine 5'-triphosphate disodium salt is a P2 purinoceptor agonist.
||Mevalonic acid is very soluble in water and polar organic solvents. It exists in equilibrium with its lactone form, called mevalonolactone, that is formed by internal condensation
||Methyl 3,5-dihydroxybenzoate was used in the synthesis of cored dendrimers.
||Vanillylamine is an alkaloid that is an intermediate in the biosynthesis of capsaicin. Vanillylamine is produced from vanillin by the enzyme vanillin aminotransferase.
||TriMetazidine EP IMpurity-D
||It is an organic compounds with molecular fomula C10H14O4.
||2,3-Dichloroanisole is a intermediate product.
||2,3-Dihydro-5-benzofuranacetic Acid is used as Pharmaceutical material and intermeidates.
||it is also called 5-Amino-2-nitrobenzotrifluoride.
||2-Trifluoromethyl thioxanthone is a pale yellow crystal with molecular fomula C14H7F3OS.
||Hypoxanthine, a purine derivative, is a potential free radical generator. It has been used in studies as in indicator, along with uric acid and allantoin, of in vivo free radical r
||Cefalexine EP IMpurity B
||Cefalexine EP IMpurity B is used as an antibiotic.
||Demeton-S-methyl Sulfone is a kind of pesticides.
||1-Methylindazole-3-carboxylic acid is an excellent solvent with a proper boiling point.
||2-Amino-5-Fluorophenol is an organic compunds.
||It has been granted the patent to have property to Inhibit protein isoprenyl transferases.
||2-Methoxybenzylamine is an organic compounds
||Methomyl is the active ingredient in commercial fly bait granules which are mixed with a cola drink to kill bothersome raccoon, skunk and opossum.
||Alodan is an organic chloride insecticide.
||Milbemycin oxime is a broad spectrum antiparasitic, used as a veterinary drug.
||Biscomate is used in the treatment of hookworms.
||Hymecromone is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the deter
||Fluorescein is a phthalic indicator dye, use as a synthetic fluorescent tracer.
||Diatrizoic Acid is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography.
||Sucralose, an artificial sweetener, is not degraded by the body, so it is noncaloric.
||Climbazole is a broad-spectrum imidazole antifungal agent with anti-dandruff benefits.
||Mesna is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide.
||Betamipron is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.
||Khellin is a vasodilator that also has bronchodilatory action.
||Ethacridine lactate monohydrate
||Ethacridine lactate hydrate is a topically applied anti-infective agent.
||Memantine hydrochloride is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.
||Fenclonine is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharm
||Deferasirox is an oral iron chelating agent used to treat chronic iron overload.
||Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
||Isosorbide dinitrate is a vasodilator used in the treatment of angina pectoris.
||Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
||Atovaquone is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
||Alarelin acetate is a synthetic GnRH agonist.
||Telbivudine is a Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of telbivudine is as a Nucleoside Reverse Transcriptase Inhibitor. The
||Bromindione is a new anticoagulant.
||Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation
||Iopromide is a low osmolar, non-ionic contrast agent for intravascular use.
||Miglitol is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
||Pidotimod is a synthetic dipeptide with immunomodulatory properties.
||Valganciclovir Hydrochloride is a hydrochloride salt form of valganciclovir, a prodrug form of ganciclovir, a nucleoside analog of 2'-deoxyguanosine, with antiviral activity. After
||Olsalazine sodium is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
||Nitazoxanide is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreduct
||Raloxifene hydrochloride is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects o
||Thiamphenicol is a methylsulfonyl analog of chloramphenicol. It is an antibiotic and immunosuppressive agent.
||Iohexol is an X-ray contrast medium containing iohexol in various concentrations, from 140 to 350 milligrams of iodine per milliliter.
||Ornidazole is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
||Deferiprone is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
||Iopamidol is an organic iodine compound and used as a non-ionic water-soluble radiographic contrast medium.
||Metolazone is a quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
||Idramantone is an immune agonist.
||Cycloserine is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
||Ezetimibe is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.
||Rimantadine hydrochloride is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
||Ibandronate Sodium is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
||Lomustine is an alkylating agent of value against both hematologic malignancies and solid tumors.
||Metaxalone (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other muscu
||Tiopronin, a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation.
||Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
||N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. S
||Amlexanox is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils
||Ronidazole is an antiprotozoal and antimicrobial agent used mainly in veterinary practice.
||(+)-α-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
||Pentamidine isethionate is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.
||Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibin
||Aminolevulinic acid hydrochloride is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
||Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-res
||Dimesna is a synthetic derivative of dithio-ethane sulfonate with uroprotective properties.
||Adefovir Dipivoxil is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes vi
||Nystatin is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis.
||Nitisinone(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
||2-Amino-5-chlorobenzophenone is used as pharmaceutical intermediates.
||Hematoxylin is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.
||Enalapril IMpurity B
||Enalapril IMpurity B is Moexipril intermediate and is the main metabolite of Imidapril.
||BroMhexine IMpurity B
||Quinolones used as MRS inhibitors and bactericides.
||It is an organic compunds with molecular fomula C8H6O3.
||Debutylbupivacaine is the intermediate of ropivacaine hydrochloride and bupivacaine.
||Carvedilol EP IMpurity E
||Carvedilol EP IMpurity E is used as a pharmaceutical intermediate.
||Used as pharmaceutical intermediates
||Nortropinone hydrochloride is used as a pharmaceutical intermediate.
||An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation o
||4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.
||2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.
||Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitri
||2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic ane
||5-Amino-4-imidazolecarboxamide is an imidazole derivative.
||Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.
||Semicarbazide is Snow white crystals and used as a reagent for ketones and aldehydes with which it affords crystalline compounds having characteristic melting points.
||Ciprofloxacin EP IMpurity A
||Fluoroquinolonic Acid is an antibiotic and antimicrobial agent.
||Ro 48-8071 fumarate
||Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
||ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.
||Z-JIB-04 is an isomer of JIB-04.
||NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
||KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells.
||TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base form.
||CID797718 is a protein kinase D1 (PKD1) inhibitor.
||Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.
||AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.
||The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally pr
||Bikinin, a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.
||Cinaciguat (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in clinical development for acute decompensated heart failure.
||P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and si
||Mertansine refers to the thiol-containing maytansinoid, DM1 (N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thio
||JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2
||S0859 is an N-cyanosulphonamide that blocks the sodium/bicarbonate cotransporter (NBC, also known as SLC4A7), which regulates intracellular pH.
||Dihydroethidium is a superoxide indicator.
||NSC-41589 is N-[2-(methylsulfanyl) phenyl]acetamide.
||AG-1557 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
||CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase captur
||Nimorazole is a nitroimidazole anti-infective.
||FH1 (BRD-K4477), a small molecule, enhances the functions of hepatocytes and promotes differentiation hepatocytes derived by iPS.
||Fexinidazole is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leis
||Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also for
||Geniposidic acid, an iridoid glucoside, used in therapy of jaundice, inflammation and hepatic disorders.
||Eburnalritardo is a vasodilator. Eburnalritardo is a vinca alkaloid and a metabolite of vincamine.
||Methyl carbamate is a white crystal.
||Cardiogenol C hydrochloride
||Cardiogenol C hydrochloride is a cardiomyogenesis inducer in embryonic stem cells.
||Dihydrocapsaicin is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsa
||Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization.
||2,4-Pyridinedicarboxylic acid is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.
||Eosin yellowish is a versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in s
||Scopolamine N-oxide HBr
||Scopolamine N-oxide HBr is an antagonist of the muscarinic acetylcholine.
||Sulfachloropyridazine is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
||Sulfamethazine sodium salt
||Sulfamethazine Sodium is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry.
||Tris(2,2,2-trifluoroethyl) borate is mostly used in condensation reactions. It has been shown to promote the direct formation of amides from carboxylic acids and amines as well a
||10-Deacetylbaccatin-III is an intermediate for taxol analog preparations with anti-cancer activity.
||Myclobutanil is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor, specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical componen
||6-Mercaptopurine anhydrous is a Nucleoside Metabolic Inhibitor. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with o
||Lithocholic acid is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorpt
||The l-carnitine hydrochloride is a constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyper
||Diaveridine (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to mammalian cells, but more studie
||Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=
||Genipin, an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.
||Dihydrostreptomycin sulfate inhibits protein synthesis by binding to the 30S ribosomal subunit. Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic with bacte
||Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective,anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has be
||Flumethrin is a pyrethroid insecticide. It is used externally in veterinary medicine against parasitic insects and ticks on cattle, sheep, goats, horses, and dogs, and the treatmen
||Cephalomannine is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.
||8-Azaguanine is a purine analogue with potential antineoplastic activity.
||Uridine, a nucleoside, consists of uracil and D-ribose by a β-N1-glycosidic bond.
||Kinetin, a type of cytokinin, has plant growth regulation effects.
||Hemicholinium-3 is a potent and selective choline uptake blocker.
||Adipic acid is a precursor for the production of nylon.
||Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.
||Cariporide (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activatio
||PI3K-IN-2 is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity. PI3K-IN-2 inhibits the PI3K kinase isoforms alpha, beta
||BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.
||RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.
||FPH2 (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
||Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
||It is a tyrosine kinase inhibitor.
||Emapunil is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
||Pixantrone dimaleate (BBR 2778 dimaleate) is an experimental antineoplastic drug.
||P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and si
||Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of
||Bimatoprost is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension.
||Robenidine hydrochloride is an anticoccidial agent mainly used in poultry.
||Succimer is a Lead Chelator. The mechanism of action of succimer is as a Lead Chelating Activity.
||Etofibrate is a combination of clofibrate and niacin, used to treat hyperlipemia.
||Nandrolone Decanoate is the decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrol
||O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of
||Ecabet sodium: a potential new agent in the management of distal colitis.
||Eflornithine hydrochloride Monohydrate
||Eflornithine hydrochloride is a specific, irreversible inhibitor of ornithine decarboxylase.
||MSDC-0160 is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
||SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
||Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
||Pimecrolimus, a calcineurin inhibitor immunosuppressant, binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction casc
||Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
||Oritavancin diphosphate is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections.
||Dalbavancin Impurity is effective against Gram positive bacteria.
||Akebia saponin D, the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
||LED209, a specific inhibitor of quorum sensor QseC of GNB, can generate a multifunctional agent PAMAM-LED209.
||Nifekalant hydrochloride is a pure potassium channel blocker and class III antiarrhythmic.
||Stachyose is a tetrasaccharide consisting of two α-D-galactose units, one α-D-glucose unit, and one β-D-fructose unit sequentially.
||Tubeimoside I(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).
||1,3-Diphenylurea is involved with Epoxide hydrolase activity.
||Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata. It is a prolyl endopeptidase Inhibitor.
||Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
||Succinic acid is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters
||Ginsenoside Rc is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
||Tetramethylpyrazine (ligustrazine, TMP), a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) shows anti-inflammation, antioxidant, antiplate
||Ketoisophorone is the major ingredients of saffron spice. It is a cyclic olefin and was reported as a product of the thermal degradation of β-carotene in aqueous suspension.
||Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity.
||Sinomenine is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
||Salvianolic acid B
||Salvianolic acid B is an active pharmaceutical compound present in Salvia miltiorrhiza, exerts a neuroprotective effect in animal models of brain and spinal cord injury.
||Scoparone can be found in a number of food items such as sweet orange, wild celery, mandarin orange (clementine, tangerine), and lemon. It is found in the Chinese herb Artemisia sc
||Epigallocatechin gallate (EGCG) is the ester of epigallocatechin and gallic acid, and is a type of catechin with anti-inflammatory effects.
||Acetylsalicylic acid, also knows as aspirin, is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or r
||Demethylcantharidin (norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.
||Neohesperidin with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
||Shikimic acid is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it.
||Cinnamic acid exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.
||Biotransformation of methyl cholate using Aspergillus niger was investigated.
||Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which wa
||Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
||The monohydrate is in the form of colorless crystals. Non corrosive. Used as a selective herbicide.
||Ginkgolide C, a natural product, can enhance the cardiac function of rats in the body.
||Deoxyadenosine, a deoxyribonucleoside, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2
||Rhoifolin is extracted from Turpinia arguya Seem dried leaves.
||Swertiamarin is a common secoiridoid found among the members of Gentianaceae with anti-inflammatory, anticancer, hypoglycemic and hypolipidemic activities.
||Madecassic acid is extracted from the whole herb of Centella asiatica.
||3,5-Diiodotyrosine is a product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or
||Naringin Dihydrochalcone(Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
||Panaxadiol is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.
||Arctiin acts on an agonists of the adiponectin receptor 1 with anti-cancer effects.
||Neohesperidin dihydrochalcone(NHDC) is an artificial sweetener derived from citrus.
||3-Aminopropionitrile fumarate is an organic compound and antirheumatic agent used in veterinary medicine.
||Gentiopicroside, a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 µM and 22.8 µM for CYP2A6;
||Orcinol glucoside (OG), an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn, shows potent antioxidative and anxiolytic activities without sedative effec
||S-Allyl cysteine (SAC), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.
||Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
||Lycorine (hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.
||Ginsenosides are a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal
||Store the product in sealed, cool and dry condition.
||Catalpol is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
||Methyl dihydrojasmonate is an ester and a diffusive aroma compound, with the smell vaguely similar to jasmine. In racemic mixtures the odor is floral and citrus while epimerized mi
||Orsellinic acid ethyl ester
||Orsellinic acid ethyl ester is a phenolic acid, extracted from lichens.
||7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis.
||Picroside I, a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable an
||Baccatin Ⅲ is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It has immunomodulatory and anticancer chemotherapeutic activities.
||Scutellarin, an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Gird
||Oridonin is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9
||Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
||Tetrahydropalmatine is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats.
||Astilbin is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
||Amygdalin has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from interv
||Coenzyme Q10 (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
||Esculetin is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour
||L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
||Aristolochic acids are a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.
||Panaxatriol can relieve myelosuppression induced by radiation injury.
||Chlorogenic acid is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
||Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
||Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
||Bilobalide, a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.
||(20S)-Protopanaxatriol(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
||Adenosine disodium triphosphate
||Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.
||Madecassoside is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activities.
||Puerarin, also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT2C receptor antagonist.
||Picroside II is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
||Glycitin, a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.
||Ethyl ferulate is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiprolifera
||Ginsenoside Rb1 is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
||Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional
||Pedunculoside is extracted from Ilex rotunda Thunb.
||Spiculisporic acid is a bioactive γ-butenolide isolated from a marine Aspergillus.
||Isoalantolactone, isolated from Inula spp., can inhibit the growth of several types of Y cells.
||Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
||S-Isocorydine(+) and its derivatives have anticancer activities.
||Dehydrocostus shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
||Morin was found to be a weak inhibitor of fatty acid synthase (IC50: 2.33 μM). Morin is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura
||Isorhamnetin is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injur
||Chrysin exhibits many biological activities and pharmacological effects, including antioxidant, anti-inflammatory, anticancer, and antiviral activities.
||Orsellinic acid is a phenolic acid extracted from lichens.
||2',4',6'-Trihydroxyacetophenone has antiobesity and hypolipidemic effects, may be partly mediated by delaying the intestinal absorption of dietary fat by inhibiting pancreatic lipa
||Tangeretin, a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and
||Hyperoside is a naturally occuring flavonoid compound which shows multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.
||Indigo is extracted from Indigo blue.
||Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxyg
||Citropten is a natural organic compound and is found in the essential oils of citrus such as lime, lemon, and bergamot.
||(-)-Epicatechin is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
||Gentisic acid is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant propertie
||Vanillyl alcohol is derived from vanillin. It is used to flavor food. It has been used in trials studying the treatment of Smoking.
||Tyrosol is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives.
||Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
||p-Coumaric acid is the abundant isomer of cinnamic acid, with antitumor and anti-mutagenic activities.
||Oleanolic acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.
||Echinocystic acid (EA), a natural triterpone enriched in various herbs, shows a range of pharmacological activities including anti-inflammatory and antioxidant effects.
||Diosgenin is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.
||Quercitrin is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities. Quercitrin can be found in a number of food items such as garden tomato (va
||Ginsenoside Re may have properties that inhibit or prevent the growth of tumors.
||Angelicin, is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.
||Mucic acid is an aldaric acid obtained by nitric acid oxidation of galactose or galactose-containing compounds.
||Ginsenoside Rd may have properties that inhibit or prevent the growth of tumors.
||Cellobiose is a disaccharide, a reducing sugar, consists of two β-glucose molecules linked by a β(1→4) bond. It can be hydrolyzed to glucose enzymatically or with acid.
||20-Hydroxyecdysone is a steroid hormone that regulates the processes of molting or ecdysis in insects.
||Genistin is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities
||Syringic acid (SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hyperg
||Aleuritic acid, or α-aleuritic acid, is a major ingredient in shellac, constituting about 35% of it. It is used as a starting material in the perfume industry for the preparation
||Trigonelline, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
||3-Hydroxy-4-methoxycinnamic Acid exhibits hypoglycemic properties.
||Hordenine, an effective phenylethylamine alkaloid, has antibacterial activities.
||Norcantharidin is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.
||Alantolactone(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator o
||Shikonin is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of
||Sclareolide is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of S
||5alpha-Cholestan-3-one(5aCh3) is an intermediate product in cholesterol metabolism, which is elevated in the case of cerebrotendinous xanthomatosis. Within the cell, It is primaril
||Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
||Fraxetin has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, ha
||3-hydroxyflavone is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, an
||Ergosterol is a steroid extracted from Ganoderma lucidum cystocarp.
||Schisantherin A is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.
||Melibiose is a reducing disaccharide formed by an alpha-1,6 linkage between galactose and glucose (D-Gal-α(1→6)-D-Glc).
||Patchouli alcohol is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions. Patchouli alcohol also suppresses inflammation induced
||Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo). It is a potent muscle relaxant.
||Sesamin is a lignan extracted from Sesamum indicum L.
||Berbamine dihydrochloride, a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.
||Schisandrin A is a main effective components extracted from the oriental medicine Schisandra chinensis, inhibits CYP3A activity with an IC50 of 6.60 μM and Ki of 5.83 μM, respect
||Trigonelline chloride, an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.
||α-L-Rhamnose monohydrate is a component of bacterial polysaccharides where it plays an important role in pathogenicity.
||Ethyl vanillin, a vanillin analog, is a flavoring agent that exhibits strong antioxidant activity.
||Alpha-Lipoic Acid is a naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive acti
||Citrulline is an α-amino acid.
||Ginsenoside Rg1, one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
||Wogonin is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.
||Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition.
||Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system.
||Antiarol is a member of aromatic phenols and exhibits moderate DPPH free radical scavenging activity.
||6-Hydroxyflavone is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common
||Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
||Psoralen is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
||5-Hydroxymethyl-2-furaldehyde is found from various carbohydrates.
||Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits the proliferation of
||Tanshinone IIA sulfonate sodium
||Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human puriner
||Ethyl vanillin acetate
||Vanillin is a phenolic aldehyde
||Schisandrin is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.
||Beta-Cyclodextrin is a member of the class of compounds known as oligosaccharides.
||Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infective agent.
||Ligustrazine is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
||Fructose is a simple ketonic monosaccharide extracted from Honey,fruits,berries,melon.
||Gibberellic acid (also called Gibberellin A3, GA, and GA3) is a hormone found in plants and fungi.
||Cedryl Acetate, an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functio
||(-)-Arctigenin is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a ligna
||Quinic acid is an acid which is found in cinchona bark and elsewhere in plants.
||Dihydrocholesterol is a cholesterol derivative found in human feces, gallstones, eggs, and other biological matter.
||Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
||Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.
||Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats f
||Stigmasterol is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol h
||Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of
||Fytic acid is a complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
||Cyclovirobuxin D is extracted from Buxus microphylla.
||L(-)-sorbose is a ketose belonging to the group of sugars known as monosaccharides.
||Vanillin is a phenolic aldehyde.
||Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema model, and has the
||DL-Menthol is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis. (–)-Menthol is more common than (+)-menthol in natur
||Chondroitin sulfate A is a derivatives of chondroitin extracted from shark bone which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. It reduces inflam
||Xanthoxylin is a borneol and camphor tasting compound and can be found in a number of food items such as fats and oils, herbs and spices, pomegranate, and sweet orange. Derivatives
||Xanthone is currently used as ovicide for codling moth eggs and as a larvicide.
||3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
||Jatrorrhizine hydrochloride is extracted from berberidis, radix.
||(-)-Epigallocatechin is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils.
||Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 rece
||4-Hydroxybenzoic acid is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more
||Rhein is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.
||Gastrodin, an anti-inflammatory polyphenol, is extracted from Chinese natural herbal Gastrodia elata Blume. and benefits neurodegenerative diseases.
||2-hydroxy-4-methoxybenzoic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(2-hydroxy-4-methoxyphenyl)propanoic acid. It is gen
||L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
||(S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
||Laurocapram is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a h
||2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhi
||Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheat
||Guanine is a purine base that is a constituent of nucleotides occurring in nucleic acids.
||Methyl stearate is found in cloves. Antifoaming agent and fermentation nutrient.
||Methyl Oleate is an unsaturated high fatty acid ester, an important chemical raw material, widely used in the preparation of surfactants, leather additives, textile additives, as w
||Oleic acid is an unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, an
||Oxalic acid is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolize
||1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline catalysed aldol con
||L-ornithine hydrochloride has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the
||1. D-(+)-Fucose is a hexose deoxy sugar found on N-linked glycans that appears on the cell surface of mammalian and plant cells.
||Cysteine is a naturally occurring, sulfur-containing amino acid which is important for protein synthesis, detoxification, and also exerts diverse metabolic functions.
||Glycine is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
||Serine is a non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for
||Aspartic Acid is a non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the cit
||L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONI
||A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
||Threonine is an essential amino acid in humans (provided by food), Threonine is an important residue of many proteins, such as tooth enamel, collagen, and elastin. An important ami
||Indole-3-acetic acid (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.
||D-Trehalose can inhibit the decomposition of collagen, so it can be used to improve osteoporosis.
||Damascenone is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.
||1. 5-Methyl-7-methoxyisoflavone is used by bodybuilders for its ergogenic properties.
||Sodium ferulate (SF), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent th
||4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
||It has the health function of killing sperm, reducing Yin, inhibiting bacteria, anti-inflammation and enhancing vagina self-cleaning.
||Used as an intermediate of emulsifier, wetting agent, stabilizer and plasticizer.
||Palmitic acid ethyl ester
||Used as softener and lubricant.
||Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection.
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.
The ability of robinin to reverse the multidrug resista
||Araloside V comes from the roots of Aralia elata. It can be used to treat neurasthenia.
||6-Hydroxycoumarin exhibits cytotoxicity against human HL60, HCT116, COLO205 cells with activity value of 35 uM, 42 uM, 37 respectively. 6-Hydroxycoumarin is a human CA9, CA12 inhi
||1. Emodin 1-O-beta-D-glucoside has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin 1-O-beta-D-glucoside shows inhibitory
||Inexpensive starting material for chiral synthesis.
||Eugenol Acetate is a constituent of Clove oil, an essential oil from the clove plant, Syzygium aromaticum. Clove oil is a natural analgaesic and antiseptic used primarily in dentis
||1. Ilexsaponin A shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.
||Pinoresinol dimethyl ether
||1. Beta-Elemonic acid exhibits anti-inflammatory effects. 2. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of bet
||1. 4-(4-Hydroxyphenyl)-2-butanone(RK) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the
||1. Ecliptasaponin A has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epith
||Sinigrin, a glucosinolate, is used as a systrate to identify, differentiate and characterize myrosinase(s)/thioglucoside glucohydrolase(s)/thioglucosidase(s). Sinigrin is used as a
||Scutellarin methylester has the effect of improving sleep, such as prolonging sleep time, increasing the incidence of sleep, shortening sleep latency, which also helps to delay agi
||1. Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth
||1. Malic acid did reduce populations of L. monocytogenes on poultry. 2. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtu
||Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
||1. 2-Methoxycinnamic acid can enhance inhibition of tyrosinase activity.
||1. Isochlorogenic acid C(4,5) has antiviral activity, including anti-HIV-1 integrase activity. 2. Isochlorogenic acid C(4,5) shows anti-hepatotoxic activity.
||Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine
||1. Ethyl 4-methoxycinnamate is an anticarcinogenic agent. 2. Ethyl 4-methoxycinnamate is a glutathion S tranferase inhibitor.
||1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's diseas
||1. Goitrin is a potent antithyroid compound found naturally in crucifers. 2. Goitrin is responsible for the induction of glutathione S-transferases.< 3. Goitrin is a moderate in
||1. Steviol, a natural sweetener, it inhibits proliferation of the gastrointestinal cancer cells intensively. 2. Steviol can induce a significant increase in CYP3A29 expression. 3.
||Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degra
||Tenacigenin B, 3-O-β-Allopyranosyl-(1→4)
||Perillartine is a sweetener, which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.
||1. Phlorizin dihydrate can significantly inhibit oxidative DNA damage.
||7β-Hydroxylathyrol is a diterpenoid extract from the seed oil of Caper Spurge and displays P-gp inhibition resulting in cytotoxic properties.
||Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for an
||1. Coixol acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to
||1. Skimmianin is a spasmolytic agent. 2. Skimmianin shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
||Naringenin trimethyl ether
||1. Naringenin trimethyl ether shows significant molluscicidal activity with a median lethal concentration (LC(5)) of 3.9 μg/mL.
||1. Nerolidol shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. 2. Nerolidol is mainly related to ROS and DNA single st
||1. Naringenin chalcone has antiallergic activity 2. Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. 3. Naringenin chalco
||1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibril
||Timosaponin A1 is a coprostane type steroidal saponin isolated from Rhizoma Anemarrhenae.
||Dehydroevodiamine, a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide
||1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber
||5-Hydroxytryptophan is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
||Batyl alcohol, isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
||4-Hydroxychalcone attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
||JUAREZIC ACID is also known as 5-Phenylpenta-2,4-dienoic acid.
||Spermine is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.
||Bovinocidin is an irreversible inhibitor of succinate dehydrogenase.
||Xanthurenic acid, a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).
||Kynurenine is synthesized by the enzyme tryptophan dioxygenase.
||Mangiferin is used for antidiabetes. Extracted from Mangifera indica L..
||Extracted from whole herb of Catharanthus roseus (L.)G.Don;Store the product in sealed, cool and dry condition.
||Abscisic acid is a compound isolated from fruits and plants.
||Melezitose is a nonreducing trisaccharide sugar that is produced by many plant sap-eating insects, including aphids such as Cinara pilicornis by an enzyme reaction.
||Protocatechualdehyde, a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae, is associated with a wide variety of biological activities and has been
||Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and
||Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines.
||Desoxycorticosterone acetate is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
||Eprazinone is a mucolytic with antitussive and mucolytic effect.
||Hederagenin is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.
||Gallein is a small molecule inhibitor of Gβγ activity.
||sancycline is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA int
||Daurisoline is a hERG inhibitor and also an autophagy blocker.
||Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
||Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae with potent anti-angiogenic activity.
||Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free radical atta
||Mycophenolic Acid Impurity
||Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of
||C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and e
||PRT4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation.
||Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated
||Nicarbazin is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. A coccidiostat for poultry.
||Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim ap
||Glycinamide Hydrochloride is a glycine pro-drug.
||Methylcobalamin is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in cli
||Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in
||Bendazac L-Lysine is an agent introduced for the management of cataracts, protecting the level of vision in patients, thus delaying the need for surgical intervention.
||Trehalose is a natural α-linked disaccharide formed by an α,α-1,1-glucoside bond between two α-glucose units.
||Salvianolic Acid C
||Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia.
||Brassinolide is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
||Harmol is a β-carboline isolated from nature.
||Citral is a clear yellow colored liquid with a lemon-like odor. Less dense than water and insoluble in water. Toxic by ingestion. Used to make other chemicals.
||Harmane is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
||Guaiazulene belongs to the class of organic compounds known as guaianes.
||HUHS015 is a potent PCA-1/ALKBH3 inhibitor.
||BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor
||IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mou
||MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.
||DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor.
||CTLA-4 inhibitor is a potent CTLA-4 inhibitor.
||Cyantraniliprole(HGW-86) is an insecticide of the ryanoid class.
||Fluensulfone is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target insects and mammals.
||4-Keto 13-cis-Retinoic Acid is a retinoic acid metabolite in neuroblastoma.
||Brevianamide F, also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance prot
||PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor rec
||Hematoporphyrin dihydrochloride is a substrate for affinity chromatography of heme-binding proteins.
||Selexipag(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the therapy of pulmonary arterial hypertension (PAH).
||16,17-Epoxypregnenolone acetate can be produced by Burkholderia cepacia SE-1.
||Euphorbiasteroid (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation.
||Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.
||MK-4827(Niraparib) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective agains
||Higenamine(Hydrochloride) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein–coupled receptors,
||Sophoricoside is effective against inflammation and can reduce the GPT.
||Dihydroactinidiolideis avolatileterpene. It has a sweet,tea-likeodorand is used as a fragrance.
||Rebaudioside A is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.
||Phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.
||Typical lots of egg yolk phosphatidylcholine have fatty acid contents of approximately 33% 16:0 (palmitic), 13% 18:0 (stearic), 31% 18:1(oleic), and 15% 18:2 (linoleic) (other fatt
||Lanolinis a wax secreted by the sebaceous glandsofwool-bearing animals.
||Geranium oil is one of the most important natural perfume.
||Citronellol is used in insect repellents and perfumes and as a mite attractant.
||Breviscapine is the total flavonoid components (the content of scutellarin > or =85%) extracted from the dried whole plant of Erigeron breviscapus.
||Betaine is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and
||N-Sulfo-glucosamine sodium salt
||N-Sulfo-glucosamine sodium salt is possible to effect reaction at arthritis.
||(S)-(+)-Carvone is the main constituent of caraway oil and pineapple seed oil.
||Tabersonineis a terpene indole alkaloid found in the medicinal plant Catharanthus roseus.
||Lysozyme is a bactericidal enzyme present in the chicken eggwhite, and it lyses gram-positive bacteria.
||Boswellic acids are a series of pentacyclic triterpene molecules that are produced by plants in the genus Boswellia.
||Calcium Carbonate is the carbonic salt of calcium (CaCO3).
||10-Hydroxy-2-decenoic acid is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
||Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.
||1-Triacontanol is a fatty alcohol of the general formula C30H62O, also known asmelissyl alcoholormyricyl alcohol. It is found in plantcuticle waxesand inbeeswax. Triacontanol is ag
||Castor Oil is a vegetable oil pressed from the seeds of the castor bean, Ricinus communis, used as a laxative and as an excipient in medicinally.
||Phytol, a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory a
||MonoMethyl auristatin F
||Monomethyl auristatin F, an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.
||Creatine phosphate disodium salt
||Creatine phosphate is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain.
||Etilefrine hydrochloride is a phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.
||Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy e
||Dihydralazine sulphate is an antihypertensive agent.
||Orotic acid zinc salt dihydrate is an intermediate product in pyrimidine synthesis.
||Bifendatatum is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.
||Benorylate is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
||Trimeprazine tartrate is aphenothiazine derivative that is used as an antipruritic. It also acts as a sedative,hypnotic, and antiemetic for prevention of motion sickness.
||Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
||Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are
||Sodium picosulfate monohydrate
||Sodium picosulfate monohydrate increases secretion of water and electrolytes and inhibits their absorption.
||Octenidine is an antibiosis.
||Sulfisomidine is a sulfanilamide antibacterial agent.
||Amifostine anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.
||Pikamilone is an intelligent medicine.
||1-Methyl-1H-pyrazol-3-amine is a chemical compound.
||D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening ap
||Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferas
||Benurestat is a urease inhibitor.
||Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone a
||SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF
||Oleanolic acid is relatively non-toxic,hepatoprotective, and exhibits antitumor and andantiviral properties.
||trans-Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
||Ursonic acid belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.
||Lycorine inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
||Angelic acid is a monocarboxylic unsaturated organic acid. Angelic acid esters are the active components of herbal medicine used against a wide range of various health disturban
||4',7-dimethoxyisoflavone, a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.
||3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast Y cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and
||Cyclohexanediamine has a potential of anticancer activity.
||RG3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both
||5-methoxyflavone is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.
||Ciwujianoside-B is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition.
||Cambendazole is one of the most effective agents for the therapy of human strongyloidiasis. Cambendazole is a nematocide effective against a variety of gastrointestinal parasites i
||Eupatilin, a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.
||Veratramine(NSC17821; NSC23880) is a potent signal transduction inhibitor for treating tumors.
||Dulcoside B (Rebaudioside C) is a natural sweeteners used for diabetics and others on carbohydrate-controlled diets.
||Macranthoidin B, a saponin extracted from Flos Lonicerae is a main bioactive saponin in rat plasma (p.o.).
||Alpha-hederin is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.
||Hederacoside C is expectorant for Cold and cough relief, Bronchitis.
||Quillaic acid is the major aglycone of the saponins in the Chilean indigenous tree Quillaja saponaria Mol.
||Dipsacoside B is a major bioactive saponin used as a marker.
||Columbianadin, one of the main bioactive constituents of the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan, has been found to possess obvious pharmacological effects
||Cynaroside is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
||Lysionotin has expectorant, eliminating phlegm, softening effects.
||Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. High-dose wilforlide A has obvious anti-inflammatory effect, but has no signific
||Cimifugin inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1,1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free
||TRX-818 is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities.
||Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a pheno
||Triptophenolide is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.
||Timosaponin BII has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1
||Epimedin C was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. It has potential
||Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
||6-Gingerol, an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other ti
||Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
||Plantamajoside has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.
||5-O-Methylvisammioside is a natural compound that isolated from the famous Chinese herbal medicines, Saposhnikovia divaricata (Turcz.) Schischk.
||Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human um
||Ezutromid is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, incr
||Polyphyllin VII, the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, ce
||Helicid is a medicine available in a number of countries worldwide.
||LYS01 free base is a new lysosomal autophagy inhibitor.
||S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
||ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).
||Vasopressin, also called antidiuretic hormone that plays a key role in maintaining osmolality. It is a neurohypophysial hormone found in most mammals. Drugs used to cause const
||Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.
||GJ103 sodium salt is an active analog of the read-through compound GJ072. Some GJ072 analogs (e.g., GJ103, GJ106, GJ109, and GJ111) consistently demonstrates their activities in al
||2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
||Vesnarinone (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic
||Anticytokinin activity was evaluated by 50% of the callus growth on the medium with kinetin but without anti-cytokinin
||Probimane had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.
||HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).
||Clofentezine is an active substance of plant protection product used as the pesticide, acaricide.
||Buprofezin is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.
||Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.
||Colistimethate Sodium is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options.
||MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein
||tert-Butyl ((3-hydroxyazetidin-3-yl)methyl)carbamate is an active biochemical agent.
||2-CHLORO-5-CYANOPYRAZINE is an active biochemical.
||Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
||Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumo
||5S rRNA modificator
||5S rRNA modificator, used in 5S rRNA RNA modification, is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules.
||SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor.
||CC-122 is an orally available pleiotropic pathway modulator with potential antineoplastic activity.
||Valrocemide, also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is
||Lvguidingan is an Anticonvulsant agent.
||SU 4942 is a bioactive chemical.
||SU 4313 is a bioactive chemical.
||SU 5214 is a modulator of tyrosine kinase signal transduction.
||NSC 247030 is a biochemical.
||1,3-Bis(4-aminophenyl)urea can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.
||Acticide WB 300 is an antiseptic.
||Sematilide (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial m
||Acecainide hydrochloride is a major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
||Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, deca
||MQAE, a fluorescent chloride ion indicator, is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is quenched via colli
||BENODANIL is a kind of fungicide.
||D-Pantothenic acid sodium salt
||Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin. For many animals, pantothenic acid is an essential nutrient. Animals require pan
||Gastrodenol is a bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease.
||Gamma-Oryzanol is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in
||Kitasamycin is a macrolide antibiotic.
||Dioxopromethazine is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia.
||Sodium Glucuronic Acid
||Sodium Glucuronic Acid is used in the treatment of hepatitis and liver cirrhosis.
||Carbocysteine is a compound formed when the iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expector
||Evofosfamide is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM) conjugated with 2-nitroimidazole, with potential antineoplastic activity. When
||Carbazochrome is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, cea
||Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
||Gamithromycin is a macrolide compound with antibacterial activity.
||Maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates
||TBA-354 is a potent anti-tuberculosis compound.
||HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).
||HTHQ, a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevate
||YM-58483 is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals.
||APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
||3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride has antibiotics activity.
||TAS-102 is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1.
||Dehydroandrographolide Succinate Potasium Salt
||Dehydroandrographolide Succinate Potasium Salt is a natural compound with anti-virus infection activity.
||Forsythoside A has antimicrobial, anticomplementary, anti-inflammatory and antiendotoxin activities. Forsythoside A inhibits Infected cells was confirmed by infecting primary chick
||Vitexin-2''-O-rhamnoside is a compound contributes to the protection against H₂O₂ -mediated oxidative stress damage.
||1-Deoxynojirimycin is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.
||ISO-1 is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages.
||4-Cyclohexylphenol is a biochemical compound for proteomics research.
||7-Bromo-2,4-diaminoquinazoline is an active biochemical.
||Pepstatin is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin.
||Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
||CHIR-090 is a very potent and selective LpxC inhibitor with antibiotic activity.
||α-santonin is a potent antiparasitic agent.
||Phenylpropanoic acid or hydrocinnamic acid is a carboxylic acid belonging to the class of phenylpropanoids. It is a white, crystalline solid with a sweet, floral scent at room temp
||Methyl trans-p-Coumarat is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of methyl 3-phenylprop-2-enoate.
||Tetrahydrocurcumin, a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.
||2, 6-dimethoxy-1, 4-benzoquinone is a member of the class of compounds known as P-benzoquinones. 2, 6-dimethoxy-1, 4-benzoquinone is slightly soluble (in water) and an extremely we
||Isovanillin is a reversible inhibitor of aldehyde oxidase. It is largely used as pharmaceutical intermediates and also applied in food and beverage industry, synthetic fragrances,
||3-Methylcatechol is an active biochemical.
||Veratric acid is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.
||3,4-Dimethoxyphenol is an active biochemical.
||Dimethyl phthalate has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in human
||Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehy
||Orcinol glucoside is anxiolytic agent without sedative effect.
||Pyrogallol is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.
||4'-Hydroxyacetophenone is a potent xanthine oxidase inhibitor.
||2', 4'-dihydroxyacetophenone is a member of the class of compounds known as alkyl-phenylketones.
||4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt
||Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cyt
||Hydrocinnamic alcohol exists in storax and fern balsam, also present in Vaccinium species fruits, guava fruit and peel, blackberry, other fruits, rum, white wine, shitake mushroom,
||Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA.
||Allitol is a substrate for the production of L-form ketoses and aldoses.
||2,6-Dimethoxybenzoic acid is an active biochemical.
||2'-Hydroxy-5'-methoxyacetophenone is an active biochemical.
||1-Octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. It is reported to possess cholesterol-lowering effects, antiag
||Hyaluronic Acid is a glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that is a component of connective tissue, skin, vitreous humour
||Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as a
||Triacontan-1-ol is an active biochemical
||Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
||Oxypaeoniflorin is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba.
||Armepavine exerted both in vitro and in vivo antifibrotic effects in rats, with inhibition of NF-κB, JunD and C/EBP pathways. It improves experimental autoimmune crescentic glomer
||Pueraria glycoside shows marked peroxynitrite.
||Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein express
||Oroxin B has antioxidant activity.
||Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.
||Fraxin is a glucoside of fraxetin.
||Lithospermoside has anti-oxidant, anti-tumor promoting activities.
||Didymin has antioxidant property. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma, may used for neuroblastoma therapy. Didymin may be a potent
||Ajugol shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml).
||20S, 20R ginsenoside-Rh1 can inhibit the thrombin-induced conversion of fibrinogen to fibrin.
||1,2,3,4,6-Pentagalloylglucose and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose (PGG) possesses pot
||Corilagin has anti-inflammatory activity.
Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.
Corilagin can enhance the cytotoxicity of b
||Ziyuglycoside I has anti-inflammatory activity, could be used as an active ingredient for cosmetics.
||Isorhamnetin 3-O-neohesperidine is a flavonol glycoside extract used as an anti-oxidant.
||Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.
||Byakangelicin is an antineoplastic agent.
||Ligustroflavone has anti-inflammatory activity.
||Nuezhenide significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a cl
||Neomangiferin has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a
||(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.
||Icariin is isolated from Epimedium herb. It can stimulate osteogenic differentiation of BMSCs and inhibit bone resorption activity of osteoclasts.
||Liriope muscari baily saponins C
||Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.
||Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces di
||20(R)-Propanaxadiol is a compound with anti-aging and antifatigue activities.
||Isorhapontigenin is a tetrahydroxylated stilbenoid with a methoxy group. It is an isomer of rhapontigenin and an analog of resveratrol. It is found in the Chinese herb Gnetum cleis
||6-Hydroxy-7-methoxycoumarin is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 6, 7-dimethoxy-2h-chromen-2-one.
||Darutigenol has obvious antithrombotic effect,its mechanism may be related to inhibition of platelet aggregation and adhesion.
||Iridin is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment
||D-Pinitol has anti-inflammatory activity. D-Pinitol exerts insulin-like activity, used for many diabetic associated conditions. D-Pinitol is a safe nutrient to reduce calorie consu
||(-)-Gallocatechin has free radical scavenging ability and moderate affinity to the human cannabinoid receptor.
||Pinosylvin induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.
||Asperuloside has anti-inflammatory activity.
||7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside is a natural product from Astragalus membranaceus
||Luteolin-7-Glucuronide possesses antioxidant activities.
||Macranthoidin A has anti-inflammation activity.
||Isobavachalcone is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with infl
||Anwuligan is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.
||Skimmin has anti-inflammatory activity, can significantly improve renal function and suppress the IgG deposition as well as the development of glomerular lesions in a rat model of
||Griffonilide is an extract from the Semiaquilegia adoxoides root, a traditional anticancer herb.
||Diosgenin glucoside and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significant inhibition of Di
||Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.
||Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fi
||Glucosylvitexin inhibits TPO activity.
||Rosiridin has cardioprotective activity.
||Scopolin formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis,and this compound
||Verbenalin induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
||Chonglou Saponin II
||Chonglou Saponin II has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.
||Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cl
||Schaftoside has antioxidant and anticancer activity.
||Emodin-8-beta-D-glucoside functions to protect from focal cerebral injury induced by ischemia and reperfusion. Emodin-8-beta-D-glucoside directly stimulates cell proliferation and
||Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.
||Epimedin A has anti-osteoporosis activities in vivo.
||Anemoside A3 is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative disea
||Ginsenoside Rb3 is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS m
||Ginsenoside Rb2 found in species of Panax, upregulating GPR120 gene expression.
||Pseudoginsenoside-F11 is a component of Panax quinquefolium (American ginseng), can antagonize the learning and memory deficits induced by scopolamine, morphine, and methamphetamin
||Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus.
||Astragaloside I is a natural product isolated from Astragalus.
||Isobavachin can facilitate mouse ES cells differentiating into neuronal cells.
||Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lan
||The main uses of benzoin are as a precursor to benzil, which is a photoinitiator.
||Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.
||Caprylic acid is found naturally in coconuts and breast milk. It is an oily liquid with a slightly unpleasant rancid taste that is minimally soluble in water. Caprylic acid is used
||Nonanoic acid is a fatty acid which occurs naturally as esters are the oil of pelargonium. Synthetic esters, such as methyl nonanoate, are used as flavorings. Pelargonic acid is an
||Hendecanoic acid appears to be involved in the control of triacylglycerol synthesis. It is found in breast milk produced by women in the United States, in infant formulas, in semin
||Myristic Acid, a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by
||Tridecanoic acid is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been identified as a substrat
||TPEN is a specific cell-permeable heavy metal chelator.
||Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.
||Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
||Glutaminase C-IN-1 is a Glutaminase C allosteric inhibitor.
||Tirasemtiv(CK 2017357) is a small-molecule fast-skeletal-troponin activator, with a potential treatment for muscle weakness and neuromuscular dysfunction.
||Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent ge
||Vulpinic Acid is a lichen metabolite with anti-inflammatory,antibacteria, properties,plant growth inhibitor.
||GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic ef
||Amcasertib is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.
||Manninotriose has the pharmacological activities, such as promoting the proliferation of hematopoietic cells, improving immunity, lowering blood glucose and anti-tumor.
||Allocryptopine induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
||Leucine is one of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulatio
||Vitamin B6 is a component of some coenzymes in human body, which is involved in a variety of metabolic reactions, especially related to amino acid metabolism.Clinical application o
||Linolenic Acid is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis
||1. Ethyl caffeate has anti-inflammatory activity. 2. Ethyl caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl caffeate is a pote
||1. Dihydrochelerythrine is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potenti
||1. Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of
||Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.
||Atractyloside potassium salt
||1. Atractyloside potassium salt inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.
||1. Crocin I has anti atherosclerosis and hypolipidemic effects.
||1. Beta-Hederin has antileishmanial activity.
2. Beta-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer.
||Used for content determination, identification, pharmacological experiment, activity screening, etc.
||1. Thonningianin A has anti-cancer activities.
2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.
3. Thonningianin A has antioxidant property,
||1. After treatment with CVGI, Raffinose family oligosaccharide was hydrolyzed effectively to yield galactose and sucrose. 2. AA-PCD resistance in Raffinose-grown cells occurs with
||1. Soyasaponin Bb can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activatin
||Piceatannol 3'-O-glucoside increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema,so it can protect lung injury.
||1. Syringaresinol-di-O-glucoside protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memo
||1. Homovanillic acid is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain. 2. Abnormalities in white matter were associated with lo
||1. Buddlejasaponin IVb(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.
||1. Denudatine has effects on action potential of ventricular fibers and has inhibition on arrhythmogenic action of aconitine.
||1. Delsoline has hypotensive effects.2. Delsoline is not only effective in preventing ventricular fibrillation and arrythmia, but can raise the intebsity of the threthold of electr
||Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.
||1. N-trans-Feruloyltyramine(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes
||Blinin, isolated from the whole plant of Conyza blinii, is used in folk medicine in the south-west of China.
||Worenine is used in the a flurophore switched probe which aids in correction of an abasic site (AP site) caused by the removal of a damaged base in DNA.
||Spirostan-3-ol is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis.
||1. Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.
||Ganoderic acid G
||Ganoderic acid G is a highly oxidized lanostane-type triterpenoid from the fungus ganoderma lucidum.
||Mogrosides IV is a sweet minor cucurbitane glycoside, it exhibits maltase inhibitory effect(IC50 : 10 mM), and with antioxidant, antidiabetic and anticancer activities.
||1. Neoruscogenin represents a universal pharmacological tool for RORα research due to its specific selectivity profile versus other nuclear receptors.
||Liriopesides B exhibited potential anticancer activity against human ovarian cancer A2780 cells.
||1. Sinomeni Caulis et Rhizoma has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. 2. Magnoflorine and Sinomenine have p
||Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
||Leucoside is a naturally occuring flavonol bioside with many biological activities.
||1. Arteannuin B has potent antimalarial activity.
||Palmatrubine shows high antitumor activity.
||1. Protopanaxdiol has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity
||1. Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.
||1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.
||Vitexin-4''-O-glucoside could effectively protect ECV-304 cells against cytotoxicity induced by TBHP through resuming mitochondrial function.
||1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts prot
||1. Parishin B can prevent vascular dementia.
||1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+
||Use of Deltaline as versatile antidotes against poisoning of animals and humans.
||1. Crassicauline A and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively.
||1. Linderene, linderalactone and isolinderalactone inhibit the enzymes from both origins to the same extent.
||1. Darutoside can as an appropriate treatment for wounds. 2. Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decrea
||1. 7-Ethylcamptothecin has the superior antitumor activity than CPT. (a). 7-Ethylcamptothecin has a stronger growth-inhibiting activity against tumor cells. (b). 7-Ethylcamptothe
||Abrine exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse al
||1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance.
||1. Rubusoside is a natural sweetener . 2. Rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties.
||N-benzylpalmitamide inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and
||Anemosapogenin shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed.
||Triterpenoid saponin. Shows expectorant, emetic and stimulant effects. Orally active.
||1. Poncirin shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis
||Usaramine demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
||1. 7-Epitaxol is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.
||Perillen is an actiive constituent in the drug which promotes enterocinesia. Perillen demonstrates strong resistance activity against staphylococcus aureus and E.coli.
||1. Caftaric acid has anti-mutagenicity. 2. Caftaric acid is an inhibitor of the protein-protein interactions mediated by the Src-family kinases.
||FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and specifically downregulates FOXM1-activated genes.
||WST-8 is a water-soluble tetrazolium dye, the sensitivity of the WST-8-based assay is higher than the conventional MTS-based assay.
||Cadazolid is an oxazolidinone-type antibiotic, with activity against gram-positive bacteria, including Clostridium difficile.
||L-Argininamide (L-Arm) is used as a model compound in studies of the physicochemical characteristic of ligand binding DNA aptamers and their potential development as fluorescent ap
||HMN-154 is a novel benzenesulfonamide anticancer compound.
||KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection following viral infection
||Khasianine has strong activity against liver damage induced by CCl4.
||Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer
||Ectoine is an osmoprotectant in a variety of microorganisms including halophilic and heterotrophic bacteria and non-halophilic bacteria such as the Streptomyces species, as well as
||AN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro. It inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM f
||Dantrolene sodium hemiheptahydrate
||Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine recepto
||Etoxazole is an acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection.
||Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.
||Hoechst 33258 is a benzimidazole anti-filarial agent. it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication. it also
||Selamectin is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus l
||LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
||FIN56 is a specific inducer of ferroptosis.
||Glycocholic Acid Sodium Salt
||Glycocholic Acid Sodium Salt is a conjugated bile salt and ionic biologic detergent. It is involved in the emulsification of fats.
||Methyl-β-cyclodextrin, a cyclic heptasaccharide, is an effective agent for the depletion of cholesterol from cells; also inhibits PEL cell growth with an IC50 of 3.33-4.23 mM.
||Chonglou Saponin VII
||Chonglou saponin VII shows inhibitory effects on cell proliferation.
||Gly-Leu is a substrate for the assay of glycyl-L-leucine dipeptidase.
||PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.
||Fabomotizole HCl (CM346 HCl), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF,
||AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming
||Sodium L-lactate is produced from pyruvate by the enzyme Lactate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. L-Lactic A
||AFN-1252(Debio 1452) is an effective inhibitor of enoyl-acyl carrier protein reductase (FabI). It (≤0.12 μg/ml) inhibits all clinical isolates of Staphylococcus aureus and Staph
||Perivine may resolve the instability of the retinoblastoma-associated proteins (RbAp48) complex and thus be used in Alzheimer's disease therapy. Perivine, vobasine, coronaridine an
||S-ADENOSYL-L-METHIONINE (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells
||<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
||Arachidonic acid is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal p
||Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.
||Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila m
||4,7-DIHYDROXYCOUMARIN is a bioactive natural compound.
||UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
||D-Luciferin Potassium Salt
||D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP.
||Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with t
||Visomitin is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).
||N-Nitroso-N-methylurea is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
||1-Methoxy PMS is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.
||NSC 191412 is an active compound.
||Loflucarban (Fluonilid) is an antimycotic compoud.
||U 19963 is an active compound.
||Adipamidoxime is an active compound.
||Cosan-528 is a bioactive chemical.
||NSC 409012 is an active compound.
||Gemcitabine monophosphate sodium salt hydrate
||Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
||Multi-kinase inhibitor I
||Multi-kinase inhibitor I is a Multi-kinase inhibitor.
||TD-198946, a potent chondrogenic agent, is a thienoindazole derivative.
||NSC19005 is structurally related to Betahistine. NSC19005 is a dimer of Betahistine.
||AHU377 calcium salt
||AHU-377 hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.AHU377 is a prodrug of LBQ657 (Item No. 19829),
||Protein degrader 1 hydrochloride
||Protein degrader 1 hydrochloride is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
||Targocil is used as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptible S. aureus (MSSA) and methicillin-res
||L-Cysteinylglycine, is a biologically important compound since it is formed during the γ-glutamyl cycle. It is a L-cysteinyl peptide, that can be used in the studies of many pepti
||Guanidinoacetic acid, a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Guanidinoacetic Acid is an important m
||T.cruzi Inhibitor (1350920-22-7(free base))
||T.cruzi Inhibitor is a Trypanosoma cruzi inhibitor.
||Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone.
||Diroximel fumarate, a prodrug of monomethyl fumarate in a controlled-release formulation, rapidly and potently converts to MMF in the body.
||Fluanisone is a butyrophenone derivative with sedative properties. It is a typical antipsychotic and is used in the treatment of schizophrenia.
||SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
||Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-pac
||Succinobucol is a novel phenolic antioxidant small molecule with anti-oxidant and anti-inflammatory properties. It designed to treat atherosclerosis of the blood vessels of the hea
||Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).
||Thiaproline has been used in peptide coupling reactions.
||Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
||CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also in
||CP 376395 is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
||Quinine Dihydrochloride is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).
||SPDB is a small fragment linked to DM4 conjugates. It conjugates to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.
||Brassinin (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities.
||Halofenozide is an ecdysteroid agonist and used as a pesticide.
||This product is isolated and purified from the leaves of Phyllostachys heterocycla
||ML239 is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.
||(4-Chloro-thiazol-2-yl)acetic acid is a chemical compound.
||Methyl 2-(Boc-aMino)-2-(oxetan-3-yl)acetate is a chemical compound.
||2,6-Dimethoxybenzoquinone (2,6-DMBQ) is a benzoquinone, a chemical compound found in Rauvolfia vomitoria and in Tibouchina pulchra.,At physiological concentrations 2,6-Dimethoxy-p-
||Roquinimex (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF
||6-CFDA N-succinimidyl ester
||The succinimidyl ester group is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mammalia
||Tirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The com
||RO1138452 is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma aden
||Tolfenpyrad is an effective insecticide, used against pests that are resistant to existing insecticides such as organophosphates and carbamates.
||S-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [
||BT-11 is an orally available LANCL2 binding compound. It is used in the therapy of inflammatory bowel disease.
||Traumatic Acid is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective ca
||Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration . It is produced by the action o
||Amifampridine is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action pote
||Bismuth subgallate is an astringent and antiseptic and is applied to skin diseases such as eczema.
||Gadopentetate dimeglumine, an extracellular intravenous contrast agent, is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-b
||Inositol nicotinate has the effect of lowering cholesterol and expanding peripheral blood vessels for hypercholesterolemia and atherosclerosis.
||Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
||Edg-2 receptor inhibitor 1
||Edg-2 receptor inhibitor 1 is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
||SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor
||Citraconic acid is a dicarboxylic acid consisting of maleic acid having a methyl substituent at the 2-position.
||ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
||Clonixin is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium
||Propacetamol is a prodrug of paracetamol (acetaminophen) with improved water solubility. Propacetamol is an analgesic drug delivered by IV when the oral application of NSAID is not
||Fursultiamine is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.
||Amylmetacresol is used in the treatment of sore throat or ‘acute sore throat’, pharyngitis, tonsillitis and laryngitis. As well as in the treatment of influenza A and SARS-CoV.
||Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depres
||Tiaprofenic acid is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
||Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM; Kd2: 27
||Pipobroman is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemi
||Desoximetasone(Topicort) is a medication belonging to the family of medications known as topical corticosteroids; is used for the relief of various skin conditions, including rashe
||AHU-377 is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.
||pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally，which can cause the secretion and synthesis of salivary proteins.
||Xanthydrol is an organic chemical compound. Xanthydrol is used to test the levels of urea in the bloodstream.
||Ethylene glycol bis(2-aminoethyl)tetraacetic acid is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino
||beta, beta-dimethylacrylshikonin has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.
||Puerarin has been investigated for the treatment of Alcohol Abuse.
||Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolit
||Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.
||A steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatidine
||Antiviral, anti HIV.
||YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of SN-38 in cancer cells and no effect on P-glycoprotein–mediated paclitaxel resistance in MDR1
||9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1
||PEO-IAA is a novel potent auxin antagonist.
||HC-056456 is a CatSper channel modulator.
||CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
||PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
||Exo1 is a chemical inhibitor of the exocytic pathway
||Siramesine(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.lysoso
||PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d)
||Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP
||Protein kinase inhibitors 1
||Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
||Fer and FerT inhibitor
||Fer/FerT kinase inhibitor
||Parimifasor is an immunomodulator, with anti-inflammatory activity.
||M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can dist
||ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.
||PKG drug G1
||PKG drug G1 targets C42 of PKG Iα. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
||QX77 is a chaperone-mediated autophagy (CMA) activator.
||ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML297 exhibits no effect on GIRK2,
||BMS-626529 is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
||SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 25
||Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).
||WM-1119 is a highly potent, selective KAT6A/B inhibitor
||Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and
||Diclofop-methyl is used as the active ingredient in many herbicides that are used to control weed growth in plants such as wheat and wild oats.
||Ciliatine belongs to the class of organic compounds known as organic phosphonic acids. Ciliatine has been primarily detected in urine. Ciliatine participates in a number of enzymat
||L-Anserine nitrate salt
||L-Anserine Nitrate Salt is a dipeptide found in most animal tissues. In model systems it is a potent antioxidant and scavener of hydroxyl radicals. The compound inhibits nonenzymat
||Aminoadipic acid (2-aminoadipate) is a metabolite in the principal biochemical pathway of lysine. It is an intermediate in the metabolism (i.e. breakdown or degradation) of lysine
||3-Hydroxyanthranilic acid, also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthrani
||Acetylgalactosamine is an important constituent of brain heteropolysaccharides (glycoproteins).
||3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in huma
||2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synth
||cis-4-Hydroxy-D-proline belongs to the class of organic compounds known as proline and derivatives. Proline and derivatives are compounds containing proline or a derivative thereof
||Phosphocholine chloride calcium salt tet
||Phosphorylcholine is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the concentration of phosphorylcholine as the
||Indole-3-methyl acetate is found in apple. It is isolated from immature seeds of beach pea (Lathyrus maritimus), Vicia amurensis, wild soybean (Glycine soja), lobiya (Vigna catiang
||Deoxyguanosine is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of DNA
||Pyrrole-2-carboxylic acid was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino
||25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also pla
||5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Uridine 5'-monophosphate is a nucleotide that is f
||D-Gulonic acid γ-lactone
||L-Gulonolactone (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 126.96.36.199), which catalyzes the last step of the bio
||Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicoti
||O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in huma
||D-Tagatose, a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods
||N-Acetylmannosamine is a monosaccharide that is used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. N-Acetyl-
||D-Glucose 6-phosphate sodium salt
||In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase dur
||The major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
||4-Acetamidobutanoic acid can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to huma
||Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is pr
||Thymidine 5'-monophosphate disodium salt
||Thymidine-5'-monophosphate (TMP) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chr
||2'-Deoxycytidine 5'-monophosphate (dCMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 188.8.131.52) to form dCDP which upon phosphorylat
||Sucrose is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
||Suberic acid is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dic
||2'-Deoxyuridine 5'-monophosphate disodium salt
||2'-Deoxyuridine 5'-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of
||Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor (IC50: 10 nM).
||Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucl
||2-Hydroxybutyric acid is formed as a by-product of the formation of alpha-ketobutyrate via a reaction catalyzed by lactate dehydrogenase (LDH) or alpha-hydroxybutyrate dehydrogenas
||Creatine phosphate disodium salt tetrahydrate
||Creatine phosphate disodium salt tetrahydrate is a substrate for the assay of creatine kinase
||Elaidic acid is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated w
||N-Formylglycine is a simple dipeptide and a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.
||UDP-Glucose sodium salt
||UDP-Glucose sodium salt is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM). It can
||5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and le
||Purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines.
||Prenol is found in blackcurrant. Prenol is a constituent of ylang-ylang and hop oils. Prenol is found in orange peel oil and various fruits e.g. orange, lemon, lime, grape, pineapp
||Glycoaldehyde Dimer is derivative of glycolaldehyde, which is the precursor molecule of various significant compounds including amino acid glycine and in the formose reaction.
||Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran,
||(2R,3R)-2,3-Butanediol is found in cocoa and cocoa products. (2R,3R)-2,3-Butanediol is isolated from cocoa butter and roots of Ruta graveolens (rue).2,3-Butanediol is one of the co
||Pyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.
||DL-2,3-Diaminopropionic acid monohydroch
||L-Tryptophanamide Hydrochloride is an amino acid amide used as a substrate for studying the action of aminopeptidase enzyme.
||Homoserine is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer to
||One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phospha
||Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation.
||3-Hydroxybenzyl alcohol (CAS Number 620-24-6) is a hydroxybenzyl alcohol that is phenol substituted at position C-3 by a hydroxymethyl group. It is a pink or beige to brown crystal
||The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine),
||L-Pipecolic acid is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adreno
||Monomethyl glutaric acid is a metabolite of dibasic esters(DBEs) by nasal respiratory and olfactory mucosae in vitro demonstrated that hydrolysis of DBEs yields mainly the monometh
||L-Norleucine is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
||Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PM
||Formamide is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been expo
||Diethyl oxalpropionate, also known as methyloxalacetic acid diethyl ester or diethyl methyloxalacetate, is a member of the class of compounds known as beta-keto acids and derivativ
||(+/-)-Leucine or DL-Leucine can be found in Green bell peppers, Green zucchinis, Italian sweet red peppers, and Red bell peppers.
||Monoethyl malonic acid
||Monoethyl malonic acid belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid gro
||Arachidic acid is a saturated fatty acid found naturally in fish and vegetable oils (such as those from peanuts). It can also be formed by the hydrogenation of arachidonic acid. Di
||Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and
||4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-methylcatechol is known to induce the pro
||Quinaldic acid, also known as quinaldate or chinaldinsaeure, belongs to the class of organic compounds known as quinoline carboxylic acids.
||N-Acetyl-L-phenylalanine is an essential amino acid produced for medical, feed, and nutritional applications. It appears in large amount in urine of patients with phenylketonuria w
||1-Phenylethanol exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). 1-Phenylethanol has been detected in multiple biofluids, such as feces
||D-Ribose, commonly referred to as simply ribose, is a five-carbon sugar found in all living cells. Ribose is not an essential nutrient because it can be synthesized by almost every
||Alpha-Hydroxyisobutyric acid is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be obtained through environmental exposure. MTBE is rapidly eliminated from the body, mainl
||Norvaline is a non-proteinogenic branched-chain amino acid. It has previously been reported to be a natural component of an antifungal peptide of Bacillus subtilis. Norvaline and o
||Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryp
||Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine. Pimelic acid is one methylene longer than a related dicarboxylic acid, adipic acid, a
||Bis(2-ethylhexyl) Phthalate plasticizer is used to impart softness and flexibility to PVC products. Bis(2-ethylhexyl) Phthalate has been implicated in obesity and insulin resistanc
||N-Acetylleucine belongs to the class of organic compounds known as leucine and derivatives. Leucine and derivatives are compounds containing leucine or a derivative thereof resulti
||Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole rin
||2,5-Dimethylpyrazine is present in asparagus, wheat bread, crispbread, Swiss cheeses, black or green tea, soya, malt, raw shrimp and squid. 2,5-Dimethylpyrazine is used as flavor a
||Pyruvic acid is an intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues
||2-Hydroxypyridine is the catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.
||Tryptophan is one of the 20 standard amino acids. The D-stereoisomer is occasionally found in naturally produced peptides (e.g. contryphan, the marine venom peptide).
||Potassium Sorbate acts as a potential antifungal agent when used in conjunction with polyethylene films. It also used as a corrosion inhibitor via corrosion mitigation.
||Agmatine sulfate salt
||Agmatine sulfate is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and
||Pyrimidines are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleoside
||Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma and has increased levels after aspirin ingestion.
||D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylation of specific proteins.
||L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
||D-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex a
||Hippuric acid is an acyl glycine formed by the conjugation of benzoic acid with glycine. Hippuric acid is a normal component of urine and is typically increased with increased cons
||6-hydroxynicotinic acid (6-OHNA) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract i
||Methylmalonate (MMA) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A. It is an indicator of Vitamin B-12 deficiency in cancer.
||2-Deoxy-D-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
||Pipecolic acid is a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF.
||N-Acetylglycine is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.
||Fructose-1P, also known as D-(-)-Fructose or D-(-)-Levulose, is classified as a member of the Monosaccharides.
||Dimethylbenzimidazole is an intermediate in Riboflavin metabolism. Dimethylbenzimidazole is the second to last step for the synthesis of alpha-Ribazole. It is converted from Ribofl
||Xylose or wood sugar is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucr
||L-Histidine monohydrochloride monohydrat
||Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a ch
||Trimethylamine is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagina i
||Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety, which consists of
||3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxyg
||Aminoisobutyric acid is a nonprotein amino acid (is an end product of pyrimidine metabolism) excreted in the urine of about 5% of healthy individuals, and high excretion is an auto
||Cytosine is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucle
||N-Acetyl-tryptophan was study for its possible anti-inflammatory and antinociceptive activities from the extraction of a Turkish plant, Salsola grandis.
||1H-Indole-3-acetamide, also known as auxin amide or 2-(3-indolyl)acetamide, belongs to the class of organic compounds known as 3-alkylindoles. Within the cell, 1H-indole-3-acetamid
||Itaconic acid, also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid ex
||Malic acid is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple.
||N-Acetyl-L-alanine is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4
||Produced in the gut microflora as one of the three main metabolites formed from the catechin diet. Its use in the production of glycol benzoates for the application of plasticizer
||Glyoxylic acid monohydrate
||Glyoxylic acid or oxoacetic acid is an organic compound that is both an aldehyde and a carboxylic acid.It is an intermediate of the glyoxylate cycle, which enables certain organism
||L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
||Lactic acid is an organic acid. It is a chiral molecule, consisting of two optical isomers, L-lactic acid and D-lactic acid, with the L-isomer being the most common in living organ
||It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabo
||PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
||Methylacetoacetic acid has been identified in the urine of patients with an inherited deficiency of propionyl-CoA carboxylase, and after isoleucine loading in the diagnosis of 2-me
||Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast
||Niacin metabolite excreted via the urinary system.
||Acetoacetic acid (AcAc) is a weak organic acid that can be produced in the human liver under certain conditions of poor metabolism leading to excessive fatty acid breakdown (diabet
||Tricosylic acid, also known as N-tricosanoate or tricosylate, belongs to the class of organic compounds known as very long-chain fatty acids.Tricosylic acid has been detected in mu
||N-Alpha-acetyllysine is a N-acetylated amino acid. It is a normal constituent of human urine with concentrations in normal samples too small to allow its routine detection; however
||Lumazine is a new MALDI matrix for complex (phospho)lipid mixtures analysis.
||4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the e
||1-Myristoyl-rac-glycerol, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains. 1-Myristoyl-rac-glycerol is used in colloi
||Serotonin creatinine sulfate monohydrate
||Serotonin creatinine sulfate complex is a neurotransmitter.
||Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic
||Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate
||DL-Homocysteine is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.
||Methyl beta-D-glucopyranoside, also known as alpha-methyl-D -mannoside or beta -D-glucopyranoside, methyl. Within the cell, methyl beta-D-glucopyranoside is primarily located in th
||Tryptophanamide belongs to the class of organic compounds known as tryptamines and derivatives. Tryptophanamide has been detected in multiple biofluids, such as urine and blood.
||Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid is broken
||γ-Linolenic acid, is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic A
||D-Allose is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refrac
||Petroselinic acid is a monounsaturated omega-12 fatty acid found naturally in plant and animal oils and fats.
||D-Glucosaminic Acid is a useful starting material for the synthesis of aldonic acids.
||Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.
||2-Hydroxyphenethylamine has been found in human testicle tissue, and has also been primarily detected in blood. 2-Hydroxyphenethylamine can be converted into 2-(hydroxymethyl)-4-(1
||Thiamine pyrophosphate is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biolo
||Palatinose is a disaccharide having an α(1→6) linkage between D-glucose and D-fructose and is similar to sucrose in its physicochemical properties. It is produced from sucrose i
||Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.
||Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Incre
||12-hydroxydodecanoic acid is the substrate of the human glutathione-dependent formaldehyde dehydrogenase.
||L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the ce
||Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown. Phosp
||D-Arabinose, also known as (+/-)-arabinose or aloe sugar, belongs to the class of organic compounds known as pentoses. D-Arabinose has been primarily detected in feces. Within the
||Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the
||Alpha-D-Glucose is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therape
||5,6-Dihydrouracil is an intermediate breakdown product of uracil.
||beta-aminoisobutyric acid is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC 184.108.40.206), the last step in pyrimidine d
||Phosphocreatine disodium salt hydrate
||Phosphocreatine disodium salt hydrate ishigh-energy phosphate reservoir in vertebrate and some invertebrate muscle; provides phosphate for ADP-ATP conversion
||Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram
||3-Nitrotyrosine is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitri
||Phenylpyruvic acid is a substrate for phenylpyruvate decarboxylase and phenylpyruvate tautomerase.
||3-(2-Hydroxyphenyl)propanoic acid, also known as melilotic acid or melilotate. Within the cell, 3-(2-hydroxyphenyl)propanoic acid is primarily located in the cytoplasm. 3-(2-Hydrox
||Spermidine inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4)
||L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose
||Cadaverine dihydrochloride, dihydrochloride salt of cadaverine (a diamine), is a biogenic amine
||D-(-)-Lyxose is used as a chiral building block.
||Inosine 5'-triphosphate trisodium salt
||InInosine 5'-triphosphate trisodium salt is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to
||Phospho(enol)pyruvic acid monopotassium
||Phosphoenolpyruvic acid, monopotassium salt is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is
||L-Histidinol dihydrochloride is a precursor of histamine and a reversible inhibitor of protein synthesis.
||(±)-Jasmonic acid methyl ester induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. More specificall
||Guanosine 5'-monophosphate disodium salt
||Guanosine monophosphate, also known as guanylic acid or 5'-GMP, belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic a
||Isoquercitrin is an effective antioxidant and an eosinophilic inflammation suppressor.
||Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat)
||Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates i
||D-Tartaric acid, also known as (S,S)-tartarate or D-threaric acid, belongs to the class of organic compounds known as sugar acids and derivatives. Within the cell, D-tartaric acid
||3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.
||N-acetyl-L-methionine is nutritionally and metabolically equivalent to L-methionine. Methionine is a dietary indispensable amino acid required for normal growth and development of
||Alpha-arbutin is a synthetic and functional active ingredient for skin lightening.
||Sodium mesoxalate monohydrate
||Mesoxalic acid is primarily located in the cytoplasm within the cell. Mesoxalic acid can be biosynthesized from malonic acid. Outside of the human body, mesoxalic acid can be found
||β-Glycerophosphate disodium salt hydrate
||β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibito
||D-Saccharic acid potassium salt
||D-Saccharic acid potassium salt is a compound formed from oxidizing sugars, which can be used to test for the presence of hepatic enzyme induction. Studies indicate that D-glucuron
||L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotect
||Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. I
||α-Ketoglutaric acid sodium salt
||alpha-Ketoglutarate is a key molecule in the TCA cycle(PMID: 26759695 ). It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of
||Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research o
||Uridine 5′-triphosphate tris salt
||Uridine 5'-triphosphate tris salt is an agonist to the P2Y receptor and has been used to study concentrations of intracellular Ca2+, as well as a phosphate donor for in vitro kinas
||7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
||α-D-Glucose 1-phosphate disodium salt hy
||α-D-Glucose 1-phosphate disodium salt is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.
||Thiamine monophosphate chloride dihydrat
||Thiamine monophosphate chloride dihydrat is a compound used in the screening of ligands that promote protein stability
||Melanin from Sepia officinalis consists of polymers of tyrosine derivatives causing darkness in skin.
||4-Guanidinobutyric acid is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid
||L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor im
||L-2-Phosphoglyceric acid disodium salt h
||2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penul
||2-methylpropanal oxime is an aldoxime derived from 2-methylpropanal. It derives from an isobutyraldehyde.
||Dihydroxyfumaric acid hydrate
||Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously
||N-Acetylasparagine, also known as acasn, belongs to the class of organic compounds known as asparagine and derivatives.
||Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
||DL-5-Hydroxylysine is a racemic mixture of D- and L- enantiomers of 5-hydroxylysine which may be used as potential target markers for radical-induced protein oxidation.
||Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environm
||N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histam
||D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT
||Fructose 6-phosphate is an important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step of the Embden-M
||α-D-Galactose-1-phosphate Dipotassium Pentahydrate
||Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars metabolism pathways.
||1-O-Oleyl-rac-glycerol, also known as monoolein, is a surfactant that releases free glycerol and oleic acid upon hydrolysis. Monoolein has been used in liquid crystal studies and r
||Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enha
||rac-Normetanephrine Hydrochloride is a metabolite of Epinephrine. It is found together with Metanephrine in urine and in certain tissues.
||Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of columbianetin acetate is a passive diffusion process without pH-depe
||3-Hydroxybutyric acid (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised
||(±)-Potassium citramalate monohydrate
||Citramalic acid is an analog of malic acid. It can inhibit the production of malic acid.
||1,2-Didecanoyl-sn-glycero-3-phosphocholi is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones s
||1,2-Dipalmitoyl-sn-glycerol is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.
||EH-201 is a low MW inducer of erythropoietin. EH-201 induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astrocytes and PC12 neuronal-like ce
||Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake
||9'-Methyl lithospermate B
||Steviolbioside is a natural sweetener, it presents notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC
||KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
||Guanosine 5'-triphosphate trisodium salt
||Guanosine 5'-triphosphate trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and
||Lanosterol is a tetracyclic triterpenoid which is the compound from which all steroids are derived.
||5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genet
||2′-Deoxycytidine 5′-diphosphate (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (220.127.116.11) for the production of dCTP to support DNA biosynthesis and revers
||Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Para
||Isoetharine mesylate salt
||Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. it also is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression.
||Calcium α-D-heptagluconate hydrate
||Calcium glucoheptonate is the calcium salt of (2xi)-D-gluco-heptonic acid. It is used as a calcium supplement for treatment of hypocalcemia.
||An antibiotic produced by Streptomyces fradiae.
||Ertapenem sodium is a new long-acting 1-β-methyl carbapenem antibiotic with a broad antibacterial spectrum including common aerobic and anaerobic bacteria and organisms with exten
||Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due t
||Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhi
||1. Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I
||1. Telocinobufagin is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of F
||Essential fatty acid. Prostaglandin precursor.
||1. Quercetin-3-O-sophoroside is the natural ligand of Bet v 1.
||1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
||1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the
||Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic receptors and chol
||1. Croceic acid is a singlet oxygen quencher.
||Alnustone exerts significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.
||1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer
||1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treatment of neurodegene
||Bullatine B shows analgesic/anti-inflammatory properties.
||1. Theaflavine-3,3'-digallate and lactic acid together could reduce herpes simplex virus transmission.
||anti-inflammatory and analgesic.
||Butylphthalide is an anti-cerebral-ischemia drug; first isolated from the seeds of Apium graveolens Linn.
||Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxioly
||Quercetin-3-O-β-D-glucose-7-O-β-D-gentiobiosiden is a flavonoid from Quercetin.
||1. Diosbulbin B exhibits potential hepatotoxicity. 2. Diosbulbin B has potential anti-tumor effects which may be related to influencing the immune system for the first time.
||1. (R)-(+)-Corypalmine shows strong papaverine-like activity.
||Pseudolaric acid A
||1. Pseudolaric acid A and -B can inhibit the growth of particular cell type.
||1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.
||1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.
||Methyl gypsogenin 3-O-beta-D-glucuronopy
||1. Gypsogenin 3-O-beta-D-glucuronopyranoside shows inhibitory activity toward pancreatic lipase with IC5 value of .29 mM, and the free carboxylic acid groups in position 28 within
||1. Magnoflorine has anti-inflammatory activity, it can inhibit inflammations.
||1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs
||1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis.
||Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat
||1. Pseudoginsenoside RT5 has anti-epilepsy,anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor
||Nystose is a tetrasaccharide with two fructose molecules linked via beta (1→2) bonds to the fructosyl moiety of sucrose.
||1. Gamma-Mangostin as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 c
||Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
||Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression
||Parishin A is isolated from the rhizomes of Gastrodia elata. It has good neuroprotective effects against brain disorders.
||Tubeimoside II(Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.
||12-Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ c
||3-Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action po
||1. Aconine is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
||1. Kirenol has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor
||1. Periplogenin plays protective roles against thyrotoxicosis and associated cardiovascular problems, are mediated through its direct antithyroidal and/or LPO inhibiting propertie
||1. 5-Isopropyl-2-methylphenol presents anxiolytic effects. 2. 5-Isopropyl-2-methylphenol presents antinociceptive activity. 3. 5-Isopropyl-2-methylphenol presents antidepressant
||1. 5,15-Diacetyl-3-benzoyllathyrol is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excel
||1. Isoginkgetin, a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of ad
||1. Narirutin has antiproliferative property. 2. Narirutin has anti-oxidant property. 3. Narirutin has anti-allergic and anti-inflammatory properties , can reduce airway inflammatio
||Diflucortolone valerate is a corticosteroid esterified with valeric acid. It helps to reduce itching, redness, and swelling.
||Methyl Aminolevulinate Hydrochloride
||Methyl Aminolevulinate Hydrochloride is commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.
||Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in
||Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone.
||Benproperine phosphate is a cough suppressant.
||Brequinar is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.
||Prostaglandin E2 (PGE2)
||Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constricti
||Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
||Nimustine has been used in trials studying the treatment of Glioblastoma.
||Eptifibatide, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.
||Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).
||Cefotiam Hexetil Hydrochloride
||Cefotiam Hydrochloride is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam
||Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
||Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migratio
||Sodium 4-aminohippurate Hydrate
||The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
||Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.
||(±)-Haloxyfop is a herbicide.
||Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.
||Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formyl methionyl tRNA. This process occurs in Escherichia coli and othe
||DL-O-Phosphoserine, a normal metabolite in human biofluid, is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by
||2-Ketobutyric acid is a product of the lysis of cystathionine. It is also one of the degradation products of threonine. It can be converted into propionyl-CoA, and thus enter the c
||Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrat
||2-Methylglutaric acid is an organic acid normally found in human urine, in healthy adults and children. It is a metabolite of succinic acid, a citric acid cycle intermediate.
||Oxalic acid dihydrate
||Oxalic acid is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolize
||Nε,Nε,Nε-Trimethyl-L-lysine is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxi
||Flavin Adenine Dinucleotide Disodium
||FAD is a flavin dinucleotide that is synthesized when the AMP moiety from ATP is transferred onto riboflavin 5'-monophosphate. FAD functions as a coenzyme that facilitates the tran
||D(+)-Glucuronic acid sodium salt monohydrate
||Glucuronic acid is a carboxylic acid and highly soluble in water. In humans, glucuronic acid is often linked to toxic or poisonous substances to allow for subsequent elimination, a
||D-Glucose 6-phosphate potassium salt
||In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase dur
||4-Methyl-2-oxopentanoic acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. It is both a neurotoxin and a metabotoxin.
||Glycocholic acid hydrate
||Glycocholic Acid is the product of conjugation of cholic acid with glycine. It is the chief ingredient of the bile of herbivorous animals.
||Disodium 5'-inosinate monohydrate
||Inosine monophosphate, or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.
||Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in
||Phytic acid dipotassium salt
||Phytic acid exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. It can be
||Threonine is an essential amino acid in humans. It is abundant in human plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lamenes
||Orotic Acid Monohydrate
||Orotic acid is an intermediate product in pyrimidine metabolism.
||Adenosine-5'-diphosphate trisodium salt
||Adenosine 5'-diphosphate sodium salt is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for
||Calcium hydroxymethionine, also known as 2-Hydroxy-4-(methylthio)butanoic acid calcium salt, is a nutrition enhancer. It exists as a solid, soluble (in water), and a weakly acidic
||Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed fr
||Pyridoxal 5'-phosphate hydrate
||Pyridoxal 5′-phosphate, the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase
||Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osmotic regulator of l
||Isocitric acid trisodium salt
||DL-Isocitric acid trisodium salt is the protonated form of isocitrate, a substrate in the citric acid cycle. It is useful as a marker for determining the composition of isocitrates
||5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is forme
||2-Methylbutanal belongs to the class of organic compounds known as short-chain aldehydes.
||Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression
||Isochlorogenic acid A
||3,5-Dicaffeoylquinic acid is a natural phenolic acid with antioxidant and anti-inflammatory activities .
||TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.
||AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.
||L-Glucose is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.
||TD139 is an inhaled galectin-3 inhibitor (Kd: 14 nM).
||Pirozadil is a hypolipidemic agent.
||SRI-011381 hydrochloride [1629138-41-5(free base)]
||SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
||L-2-Phosphoglyceric acid disodium salt hydrate
||2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penul
||Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
||Eptifibatide, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.
||Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhi
||MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
||C-176 is a highly potent and covalent mouse STING inhibitor.
||Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.
||Deacetyltaxol is extracted from Taxus brevifolia barks.
||SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).
||KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.
||SBI-0640756 (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.
||AMZ30 is a selective inhibitor of PME-1 (IC50: 600 nM). It also reduces the demethylated form of PP2A in living cells.
||PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator(hPANK3,IC50:1.3 nM).
||PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
||DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.
||DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor (IC50: 0.12 μM).
||Glyceryl trilinoleate is a very common fatty acid and is useful in studies concerning the effects of fatty acids on lipid and cholesterol handling in organisms and for studies inve
||Lithium potassium acetyl phosphate
||Acetyl phosphate is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. It is generated from sulfoacetaldehyde, converted to acetyl-CoA and ac
||Cholesteryl linoleate is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-L
||L-Threonic acid Calcium Salt
||Threonic acid is probably derived from glycated proteins or from the degradation of ascorbic acid. It is a normal component is aqeous humour and blood. Threonic acid is a substrate
||Phenylacetylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs, rats,
||D-threitol is the D-enantiomer of threitol. It has a role as a human metabolite. It is an enantiomer of a L-threitol.
||L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produc
||Lactic acid is an organic acid. It is a chiral molecule, consisting of two optical isomers, L-lactic acid and D-lactic acid, with the L-isomer being the most common in living organ
||2-Hydroxy Hippuric Acid
||2-Hydroxy Hippuric Acid (Salicyluric acid) is a metabolite of Salicylic Acid.
||N-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large dos
||Heneicosanoic acid (HEA) is a fatty acid found in human milk fat. HEA is also a part of the phospholipids of the articular cartilage boundary lubricant. HEA is a constituent of red
||2-Hydroxycaproic acid is a branched-chain alpha-keto acid that has been reported in normal human blood and in normal amniotic fluid. It has been found that 2-Hydroxycaproic acid is
||Methylhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be us
||Glycerol Tridecanoate is also known as triacylglycerols or triacylglycerides. The triglycerides are rebuilt in the blood from their fragments and become constituents of lipoprotein
||Nicotinuric acid is an acyl glycine which is normally minor metabolites of fatty acids. Acyl glycines are produced through the action of glycine N-acyltransferase.
||DL-Indole-3-lactic acid is a reactant for the preparation of antibacterial agents.
||Methylsuccinic acid is a normal metabolite found in human fluids. Increased urinary levels of Methylsuccinic acid (together with ethylmalonic acid) are the main biochemical measura
||alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. alpha-Ketoisovaleric acid is a neurotoxin, an acidogen,
||N-methylnicotinamide is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-methylnicotinamide indicates nia
||Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the
||1-Methylhydantoin is a small molecular weight polar substance, the product of degradation of creatinine by bacteria. In mammals, the metabolism of 1-methylhydantoin occurs via 5-hy
||Hexadecanedioic acid is activated by mitochondrial and microsomal fractions in the liver. It has antitumor activity.
||1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies foc
||4-Cholesten-3-one is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals.
||TG(20:0/20:0/20:0) is a triarachidic acid triglyceride. Triglycerides (TGs) are also known as triacylglycerols or triacylglycerides. TGs are the main constituent of vegetable oil a
||PE(14:0/14:0) is a phosphatidylethanolamine (PE or GPEtn). It is a glycerophospholipid in which a phosphorylethanolamine moiety occupies a glycerol substitution site. PE(14:0/14:0)
||Aminomalonic acid (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. T
||Isovalerylglycine (IVG) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inb
||3-Hexenedioic acid is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disord
||Trimethylamine N-oxide dihydrate
||Trimethylamine N-oxide (TMAO) is an oxidation product of trimethylamine and a common metabolite in animals and humans. In particular, trimethylamine-N-oxide is biosynthesized endog
||3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are rai
||1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats, coco butter, and sesame oil.
||1,6-anhydro-b-D-Glucose (Levoglucosan) is an anhydrohexose that is the 1,6-anhydro-derivative of beta-D-glucopyranose. It is formed from the pyrolysis of carbohydrates, such as sta
||Phenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally
||Undecanedicarboxylic acid is an unusual odd-numbered dicarboxylic acid that appears in the urines of children with neonatal adrenoleukodystrophy and Zellweger syndrome, as an addit
||3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so th
||Glycodeoxycholic acid sodium salt
||Glycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes e
||5-Hydroxymethyluracil is an oxidation damage product derived from thymine or 5-methylcytosine. It is a product of thymine dioxygenase. Additional deamination products such as 5-hyd
||Retinal is a carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein o
||Homocitrulline is a metabolite that can be detected in larger amounts in the urine of individuals with urea cycle disorders. The accumulation of carbamyl phosphate due to a deplete
||Glycochenodeoxycholic acid sodium salt
||Glycochenodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of th
||2-Methylglutaric acid is an organic acid normally found in human urine, in healthy adults and children. 2-Methylglutaric acid is a metabolite of succinic acid, a citric acid cycle
||2-Octenoic acid is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma.
||trans-3-Indoleacrylic acid is a Tryptophan metabolite.
||p-Hydroxymandelic acid is an acidic metabolite of p-octopamine and p-synephrine (p-phenylephrine). It is also a naturally occurring metabolite of tyramine.
||Phenylacetylglutamine is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound. Phenylacetylglutam
||Glycerol Tri-n-octanoate belongs to the family of triradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is e
||N-Acetyl-L-glutamic acid (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu a
||D-Arabitol is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-pro
||N-Acetylornithine is a minor component of deproteinized blood plasma of human blood. Human blood plasma contains a variable amount of acetylornithine, averaging 1.1 +/- 0.4 μmol/L
||5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic
||3-Methoxybenzenepropanoic acid is a naturally occurring human metabolite, It is an organic acid and excreted in human urine.
||2-Hydroxy-3-methylbutyric acid (2-hydroxyisovaleric acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothi
||Phenyllactic acid is a product of phenylalanine catabolism. An elevated level of phenyllactic acid is found in body fluids of patients with or phenylketonuria.
||2,5-Furandicarboxylic acid is a normal urinary metabolite in humans. 2,5-Furandicarboxylic acid is also a microbial metabolite, a product of the oxidation of hydroxymethylfurfural
||Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocy
||3-Furoic acid is an organic acid regularly occurring in the urine of healthy individuals. 3-Furoic acid is also a compound found in honey and honeydew samples.
||5-Hydroxymethyl-2-furancarboxylic acid (Sumiki's acid) is a naturally occurring human metabolite. Sumiki's acid was first identified in the urine of a leukemia patient who was excr
||Ethylmalonic acid can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid i
||3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particula
||3-Methylindole, or skatole occurs naturally in feces (it is produced from tryptophan in the mammalian digestive tract), beets, and coal tar, and has a strong fecal odor. In low con
||Ribothymidine is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy cont
||NADH, disodium salt hydrate
||NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH becomes oxidized to produce NAD+
||Ureidosuccinic acid is an intermediary product in pyrimidine biosynthesis.
||3-methylthiopropionate is one of the metabolites of methionine (especially of D-methionine). Cultures of Streptomyces lincolnensis accumulated 3-methylthioacrylic acid in amounts d
||Glycylglycine (Gly-Gly) is a dipeptide used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptide
||N-Acetylaspartic acid is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from t
||Cytidine 5'-triphosphate (disodium salt)
||Cytidine 5'-triphosphate (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases
||N-alpha-Acetylarginine is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population.
||L-3-Phenyllactic acid (or PLA) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via the action of lactate dehydrogenase
||Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport ch
||Acetyltyrosine is a side chain reaction of tyrosine. It converts to tyrosine and then can be used in neurotransmitter treatment as a precursor of cathecholamine.
||Maltotriose is a common oligosaccharide metabolite found in human urine after maltose ingestion or infusion. Maltotriose is increased in Glycogen storage disease II due to a mutati
||Hydroxyisocaproic acid is an end product of leucine metabolism in human tissues such as muscle and connective tissue. It belongs to 2-hydroxycarboxylic acid group of amino acid met
||Octadenol is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardati
||Indole-3-propionic acid (IPA, indole-3-propionate, or indolepropionic acid), is a deamination product of tryptophan formed by symbiotic bacteria in the gastrointestinal tract of ma
||4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.
||Formic acid is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron tr
||Crotonic acid is fatty acid formed by the action of fatty acid synthases from acetyl-CoA and malonyl-CoA precursors. It is involved in the fatty acid biosynthesis. It is also found
||D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids ma
||Isethionic acid sodium salt
||2-Hydroxyethanesulfonate (2-Hydroxyethanesulfonic acid or isethionic acid) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals
||Senecioic acid appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid
||L-alpha-Aminobutyric acid, also known as (S)-2-aminobutanoic acid, homoalanine, 2-AABA, ethylglycine, or L-butyrine, is a member of the class of compounds known as L-alpha-amino ac
||Methylamine occurs endogenously from amine catabolism and its tissue levels increase in some pathological conditions, including diabetes. Interestingly, methylamine and ammonia lev
||ortho-Hydroxyphenylacetic acid (2-hydroxybenzeneacetic acid) can be found in a number of food items such as natal plum, lemon verbena, half-highbush blueberry, and parsley, which m
||Dimethylamine (DMA) is abundantly present in human urine. Main sources of urinary DMA have been reported to include trimethylamine N-oxide, a common food component, and asymmetric
||Crocin (Gardenia Fruits Extract)（42553-65-1）
||Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidem
||pyridoxal isonicotinoyl hydrazone
||Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo.
||Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
||Tulipalin A (2-Methylenebutyrolactone) which has some phytotoxicity is a natural compound extracted from Tulipa gesneriana.
||Nifurtimox is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi epimastigotes, respectively).
||Sugammadex, a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.
||VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
||S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits the growth of mouse and human glioblastoma (GBM, IC50: 470 nM).
||IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
||MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
||SP-420 is a novel orally active iron chelator.
||V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).
||Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.
||ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).
||RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair.
||DL-Dithiothreitol (DTT) is a reagent for maintaining SH groups in the reduced state.
||L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GS
||NAcM-OPT is a specific, reversible inhibitor targeting N-Acetyl-UBE2M interaction with DCN1 （IC50: 79 nM).
||D3-βArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
||GSK 2983559 (RIP2 kinase inhibitor 1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
||DDR1-IN-2 (DDR1 inhibitor 7rh) is a potent, selective, ATP-competitive Discoidin domain receptor 1 (DDR1) inhibitor (IC50: 6.8 nM in cell-free kinase assays).
||DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).
||SNAP-94847 is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice.
||γ-GT is used as a synthetic substrate for gamma-glutamyltransferase (GGT) to determine GGT activity.
||DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).
||Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms,
||KDU691 is a PI4K inhibitor.
||CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. characterized by a high level of conservation among vertebrates and a predominant expression in the c
||Etosalamide is an antipyretic and analgesics agent.
||ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity
||CIBACRON BLUE 3G-A
||Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease
||Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.
||3-methyltoxoflavin is an effective inhibitor of protein disulfide isomerase (PDI) and its IC50 value is 170 nM.
||HT-2157 is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).
||SN 6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)
||Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain
||JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-speci
||YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM and 49.31 μM , r
||K-Ras-IN-1 is a K-Ras inhibitor.
||LAZABEMIDE(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
||ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)
||SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s o
||TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
||RU.521 (RU320521) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
||Pyronaridine also known as Malaridine, is an antimalarial drug.It inhibits the growth of P. falciparum during the asexual stage and early gametocyte stages (I and II) with an IC50
||diABZI STING agonist-1 trihydrochloride
||diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
||Bropirimine (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.
||NMDAR antagonist 1
||LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM)
||SJA710-6 is a small molecule able to selectively differentiate MSCs toward hepatocyte-like cells.
||Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocyte. Triacetonamine
||Helicin is a beta-D-glucoside resultng from the oxidation of the benzylic hydroxy group of salicin to the corresponding aldehyde. It has a role as a metabolite. It is a member of b
||(-)-Verbenone is an important component of the essential oil from rosemary. It is also an insect pheromone with a spicy odor and camphoraceous fragrance.
||Melamine is a widely-used intermediate, mainly employed as a raw material for producing melamine resin. It is also a metabolite of cyromazine formed in the body of mammals who have
||2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease.
||Levulinic acid, derived from the degradation of cellulose, is a precursor for the synthesis of biofuels, such as ethyl levulinate.
||1,3,5-trimethoxybenzene is a methoxybenzene carrying methoxy groups at positions 1, 3 and 5. It has been found to be a biomarker of flavonoid consumption in humans. It has a role a
||5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone
||Propylparaben is an antimicrobial agent, preservative, flavouring agent
||Carboxin appears as off-white crystals. Systemic fungicide and seed protectant.
||Dicyclanil, a regulator of insect growth, is a veterinary medicine for the protection against early-season myiasis.
||Methyl nicotinate is the methyl ester of that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The act
||Cyclohexanecarboxylic acid is a flavouring ingredien
||Tricarballylic acid is an inhibitor of aconitase
||Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin.
||Ethyl Maltol is an extract from medicinal plants such as P. Incarnata and can be used as an anticonvulsant. It is also a common flavoring.
||Tetradecanedioic acid is a C14 dicarboxylic acid.
||H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones
||Beta-leucine is a beta-amino acid that is pentanoic acid substituted at positions 3 and 4 by amino and methyl groups respectively. It has a role as a human metabolite.
||Forchlorfenuron (KT-30, CPPU)
||Forchlorfenuron is plant growth regulator and cytokinin; can be used to increase fruit size of fruits.
||2-Benzoxazolol is found in cereals and cereal products. 2-Benzoxazolol is found in rye seedlings.
||Coenzyme Q9 (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.
||L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vitamin) C.
||1-Naphthaleneacetate is used as a plant Growth Regulator that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fung
||Triacanthine, which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic.
||Apocarotenal (trans-β-apo-8'-carotenal) is a carotenoid found in spinach and citrus fruits. Apocarotenal is used in fat-based food (margarine, sauces, salad dressing), beverages,
||D(+)-Turanose is a naturally occuring compound. It is a reducing disaccharide.
||Sodium phytate hydrate
||Sodium phytate is known to function as a [PO4]3- storage depot and a precursor for other inositol phosphates and pyrophosphates. It is a potent chelator of divalent and trivalent c
||CGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes
||cis,cis-Muconic acid is a naturally-occurring organic acid. It is used in the manufacture of several widely-used consumer plastics. Its microbial production via extending the shiki
||H-Gly-Pro-OH is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism
||2-(4-Methoxyphenyl)acetic acid is a plasma metabolite, found in normal human urine, cerebrospinal fluid, and brain tissue.
||Acetosyringone(AS) is a phenol secreted by wounded plant tissues.Acetosyringone is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions.
||Ala-Gln, a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glut
||Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a variety of bioactive
||2-Acetylpyrazine is a flavoring ingredient. 2-Acetylpyrazine is an avolatile flavor constituent of wheat and rye bread crust.
||cis-3-Hexenyl hexanoate, existing in some fruit, has strong diffuse fruit aroma.
||Hexyl hexanoate is found in alcoholic beverages. Hexyl hexanoate is used in fruit flavouring. Hexyl hexanoate is present in many fruits, Parmesan cheese, alcoholic beverages and bl
||Phthalic acid is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.
||Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.
||3-Methylbutanoic acid is a naturally occurring aroma compound found in Bartlett pear brandies, vanilla beans, rape-honey, and banana.
||Squalane is a naturally occurring lipid in both plants and animals. It is usually used as a moisturizer and emollient in cosmetics manufacturing.
||3-oxoglutaric acid or acetonedicarboxylic acid is a simple carboxylic acid, which may be used as a building block in organic chemistry. It has been found to be a microbial metaboli
||Benzyl acetate is a constituent of Jasmin and of the essential oils of ylang-ylang and neroli.
||Diethyl malonate is naturally occurring in grapes and strawberries.
||Propylene Glycol is a propanediol that consists of propane where the hydrogens at positions 1 and 2 are substituted by hydroxyl groups AND often used as an excipient in medicines
||Fenchol is a hop-derived aroma compound commonly found in beer.
||Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It ex
||Bisphenol B has a binding affinity for estrogen receptors.
||Atrazine is an herbicide that does not occur naturally,and is a selective triazine herbicide. Atrazine is also a potent endocrine disruptor.
||Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca²⁺ homeostasis and cell viability in different cell models.
||p-cumylphenol can treat R enal Tubular Cyst Formation in Newborn Rats.
||Triflumuron is an insecticide belonging to the group of so-called insect growth regulators. It inhibits the synthesis of chitin by the insect larvae, causing the die.
||Novaluron is a benzoylurea insecticide, a member of monochlorobenzenes, an aromatic ether and an organofluorine compound.
||Lufenuron is a chitin-synthesis inhibitor.
||RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production.
||Nerol is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
||Cinnamic acid has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, pro
||6-Methylcoumarin (6MC) is a semisynthetic coumarin with important in vitro and in vivo anti-inflammatory activity.
||4-Allylanisole is found in allspice，and is a constituent of many essential oils. 4-Allylanisole is a flavouring agent.
||2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor
||Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.
||Cinnamyl acetate is a naturally occuring compound used as a flavouring agent.
||Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer c
||3,4-Dimethoxybenzaldehyde has antifungal activity .It is found in Cymbopogon javanensis.
||The adamantane moiety is the structural backbone of numerous compounds and the physicochemical and biological properties of organic polyhedral compounds with practical application
||2-Adamantanone is a bioactive chemical.
||methyl isoeugenol (MIE) is a natural food flavour that constitutes 93.7% of an essential oil from Pimenta pseudocaryophyllus leaf. The leaf extracts of this species are used as a c
||5-hydroxy-1-tetralone as the fluorescent labeling reagent.
||Lactose is the major sugar present in milk and the main source of energy supplied to the newborn mammalian in its mother's milk. Lactose is also an important osmotic regulator of l
||Bovine albumin is a globular protein that is used in numerous biochemical applications.
||geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.
||Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.
||Acetic acid octyl ester
||Acetic acid octyl ester is the acetate ester of octan-1-ol. It has a role as a plant metabolite.Acetic acid octyl ester is present in citrus peel oils.
||Citric acid monohydrate
||Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It mai
||Isobutylparaben is a preservative and preservative insecticide.
||Isophorone is a clear liquid that smells like peppermint. It can be dissolved in water and evaporates somewhat faster than water.
||Isophorone (3,5,5-trimethyl-2-cyclohexen-1-one), a monoterpene, and the structurally related 1,8-cineole and camphor, have demonstrated a protective effect against cancer, biologic
||H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
||Ethyl 3,4-dihydroxybenzoate(EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.
||2-METHYLVALERIC ACID is a natural product.
||Isopropylparaben is a preservative and preservative insecticide.
||20-DEOXYINGENOL is a natual product.
||Pyrroloquinoline quinone (PQQ), as a well-known redox enzyme cofactor, PQQ can protect NS/PCs against glutamate toxicity associated with ROS-mediated mitochondrial pathway,
||Methoxatin disodium salt
||Methoxatin disodium salt, an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic
||Usnic Acid sodium
||Usnic Acid sodium is a natual product.
||Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.
||Dimethyl succinate is found in nuts. Dimethyl succinate is present in roasted filberts. Dimethyl succinate is a flavouring ingredient.
||BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
||β,β-Dimethylacrylalkannin is a natural product isolated from Arnebia nobilis Reichb.f, increases collagen and involucrin content in skin cells.
||(E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]- has Anti-inflammatory, analgesic function.
||8-epidiosbulbin E acetate
||8-Epidiosbulbin E acetate (EEA), a furanoid, was unexpectedly found to be the most abundant diterpenoid lactone in certain varieties of Dioscorea bulbifera L. (DB), a traditional h
||GALANGIN-3-METHYLETHER has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the
||Pinocembrin 7-O-beta-D-glucoside is a natual product isolated from Penthorum chinense Pursh.
||Methylnissolin-3-O-glucoside has anti-inflammatory effects,antioxidant activity.
||Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activi
||2"-O-β-L-Galorientin is a natual product isaolated from Trollius chinensis Bunge.
||L-ABRINE is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.
||Vitexia-glucoside is a natural product isolated from Briza stricta.
||Boldine is a natual product .Boldine displays anti-cancer, cytoprotective , anti-oxidant and anti-inflammatory activities.
||DL-Menthol is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.
||Neogambogic acid , an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of pro
||Specneuzhenide is a phenol glycoside isolated from Ligustrum sinense. Specneuzhenide (Nuezhenide) possesses anti-tumor activity,has anti-angiogenic and vision improvement effects.
||OsMundacetone is a natual product isolated from Rhizoma osmundae.
||MALTOHEXAOSE is a natural saccharide, and can be produced from amylose, amylopectin and whole starch.
||1-Kestose shows significant anti-hydroxyl radical potential. 1-Kestose can promote intestinal Lactobacillus number, and influence the microorganisms as well as the intestinal and s
||Xylotetraose is a hydrolysis product of Xylan. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose.
||Deacetyl asperulosidic acid methyl ester
||Ddeacetyl asperulosidic acid methyl ester is a natual product isolated from the herbs of Hedyotis diffusa Willd,it can lower the blood glucose level in normal mice.
||Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
||7-Epi-10-deacetyltaxol shows IC50 values of 0.085 nM, against HeLa cells.
||(25RS)-Ruscogenin is a natual product.
||Pseudolaric acid B-glucopyranoside
||Pseudolaric acid B-glucopyranoside is a natural product from Pseudolarix amabilis.
||Isodemethylwedelolacton is a natual product,has Clotting activity.
||ISOBERGAPTEN is a plant growth regulating substance, it is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum maximum; it may form
||AIDS031406 is a natural product Psychotria ipecacuanha.
||7-Xylosyl-10-deacetyltaxol paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.
||Oxyberberine is isolated from the methanol extract of A. mexicana. It has been used to study the SW480 human colon cancer cell line.
||Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development o
||Gipsoside is a natural product.
||Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors
||Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity.
||SINOACUTINE is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.
||Notoginsenoside Ft1 is a saponin originally isolated from P. notoginseng with diverse biological activities
||REBAUDIOSIDE B tastes about 150 times sweeter than sucrose and it is non-caloric.
||Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.
||Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
||Coclaurine is a natural product.
||Isovanillic acidis is a natural product isolated from Senecio scandens, and shows distinct anti -inflammatory activities.
||Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited R
||1F-Fructofuranosylnystose is a kind of Fructooligosaccharides which are naturally occurring sugars with potentially beneficial nutritional effects.
||Phaseoloidin, a homogentisic acid glucoside from Nicotiana attenuata trichomes, contributes to the plant's resistance against lepidopteran herbivores.
||Taraxasterol acetate has anti-inflammatory activity in bino rats against carrageenan, formaldehyde and adjuvant induced inflammations. Taraxasterol acetate also displays potential
||Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.
||XYLOTRIOSE is a natural xylooligosaccharide, acts as a bifidogenic factor.
||1,1,1,1-Kestohexose is a natural product isolated from Poa ampla.
||Fructoheptasaccharide belongs to fructooligosaccharides (FOS) with degree of polymerization (DP=7).
||Rebaudioside M is a natural non-calorie sweetener isolated from Stevia rebaudiana Bertoni,is a glycoside of the ent-kaurene diterpenoid aglycone.
||Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal a
||Arecaidine hydrochloride may have carcinogenesis.
||Praeruptorin C (Pra-C), an effective component in the root of Peucedanum praeruptorum dunn, a traditional Chinese medicine, may function in neuroprotection.
||Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharm
||D(-)-Tartaric acid found in many plants, particularly tamarinds and grapes,it is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administ
||Pneumocandin B0 is a natural product and a key intermediate in the synthesis of the antifungal agent.
||Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.
||Stachyose is a natual product,it highly promotes proliferation of lactic acid bacteria (LAB) by inducing LAB to produce more α-galactosidase to hydrolyze stachyose.
||HYOSCINE HYDROCHLORIDE versus placebo in preventing motion sickness has been shown to be effective.
||QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio Species( SmcR with an EC50 of 208.9 nM).
||BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release).
||5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
||D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
||BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.
||Myrcene is a terpene that has been found in Cannabis and has antioxidative properties.
||Eprinomectin is an avermectin with anthelmintic and insecticidal activities.
||Tamerit as an efficient inhibitor of oxidative burst in monocytes.
||Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide.
||Ezatiostat is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity.
||2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.
||2-Methoxybenzoic acid is a novel antiemetic which prevents nausea and vomiting in humans.
||4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissi.
||TDCPP is classified under the chlorinated trialkyl organophosphate flame retardant (OPFR) group of compounds primarily utilized as additives in commercial products.
||3-Bromopyruvic acid is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of pl
||4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine.
||N-Acetyl-d-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.
||5-Methoxysalicylic acid is a natural product, used as a useful matrix in the MALDI MS analysis of oligonucleotides when combined with spermine
||Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 μM for mushroom tyrosinase.
||2,4-Dihydroxybenzoic acid is found in alcoholic beverages.2, 4-Dihydroxybenzoic acid is a food flavour ingredient and flavour modifie.
||D-erythro-Sphingosine is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
||5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.
||Sulbutiamine is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.
||Folcisteine is a plant growth regulator.
||D-chiro-Inositol is an epimer of myo-inositol that is found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bi
||Fmoc-N-Me-Phe-OH is a peptide inhibitor of Malaria Parasite
||6-Methoxysalicylic acid may be employed as internal standard for the determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic acid (SA),and exhibits
||Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.
||Anthraflavic acid, a flavonoid, is a potent IQ mutagenicity and cytochrome P-448 inhibitor.
||4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
||Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor and a unique fungicide for control of Pyricularia oryzae on rice.
||Menadione sodium bisulfite
||Menadione sodium bisulfite(MSB, also known as vitamin K3),is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K suppl
||Ethacridine lactate is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
||DL-Homocysteinethiolactone hydrochloride is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing oxid
||2,3-Diaminopropionic acid hydrochloride
||2,3-Diaminopropionic acid hydrochloride is a competitive inhibitor of cystathionase (CTH).
||1-beta-D-Arabinofuranosyluracil isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has anti-inflammatory activ
||2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
||2,2'-Cyclouridine is a research tool for antiviral and anticancer studies.
||3-methoxybenzoic acid is a food additive,and has antibacterial activity.
||O-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-phenanthroline protects mammalian cell
||Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite .
||3-Hydroxypicolinic acid is a picolinic acid derivative, and belongs to the pyridine family.
||Oxonic Acid (potassium salt)
||Oxonic Acid (potassium salt) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats.
||Dimethyl biphenyl-4,4'-dicarboxylate is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis.
||ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nM respectively). ARN-3236 Has ant
||KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity.
||1. Bufotaline is a kind of poisonous secretions of toads.
||1. Betulonic acid amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative
||1. Chelidonine isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelido
||1. Coptisine chloride can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
||1. Peimisine can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth musc
||1. Isosakuranetin has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivit
||1. Pseudoprotodioscin has moderate cytotoxicity.
||1. Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases
||1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-ove
||1. Rhaponticin(Rhaponiticin) can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice, indicates that rhaponticin has a noticeable antidiab
||It is a lignan glycosides from the bark of Albizzia myriophylla.
||Rotundic acid, a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), an
||1. Rhodojaponin II correlates pretty well with cardiotoxicity.
||1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin I
||1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
||Sec-O-glucosylhamaudol has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal sec-
||1. Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sen
||1. Citric acid (1-2̵g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans
||1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic eff
||1. Gelsemine has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammato
||1. Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-A<sup>y</sup>diabetic mice.
||1. Shionone has anti-tussive and anti-inflammatory effects.
||Picroside III, an iridoid glucoside found in the root of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae), and its subtype Picroside II has been demonstrated to reduce apopt
||1. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The inducti
||1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro
||Oroxin A has antitussive and expectorant effects.
||1. Palmatine is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the trea
||1. Columbamine shows strong activity with IC5 48.1 µM. 2. Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells w
||Isoastragaloside II is a derivative Astragaloside I, an ingredient in Astragalus membranaceus which is reported to have osteogenic properties.
||1. Oleandrin, the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin a
||1. N-Methylcytisine's nicotinic receptors have high affinity (KD = 5 nM)to nAChR from squid optical ganglia. 2. N-Methylcytisine and N,N-dimethylcytisine did not displace 14C-tuboc
||3,29-Dibenzoyl karounitriol is a natural product from Trichosanthes kirilowii Maxim.
||1. Wilforgine exhibits insecticidal activity of some degree.
||1. Triptonide is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregul
||Forsythoside E is a natutal product isolated from fruits of forsythia suspensa.
||1. Neferine has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase
||1. Liensinine,a kind of isoquinoline alkaloid,can antagonize the ventricular arrhythmias.
||Ganoderic acid C6
||1. Ganoderic acid C6 has antinociceptive activity.
||Ganoderic acid D
||1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells
||1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new vista
||1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability
||1. Herbacetin induces apoptosis in HepG2 cells, by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting
||(+)-Pteryxin has muscle-relaxant props. (+)-Pteryxin shows hepatoprotective and nitric oxide prodn. inhibitory activity.
||1. Nodakenetin has clinical efficacy.
||1. Cinnamyl alcohol readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.
||1. 3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 1.5 m muM.
||Notoginsenoside Fe is a natural compound isolated from Panax japlcus var.
||Apiopaeonoside is a natural product isolated from the root of Paeonia suffruticosa
||1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the
||1. Napellonine shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.
||1. Yunaconitine has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg
||1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48̵µg/mL.
||Schisandrin C is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.
||1. Alpha-Cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. Alpha-Cyperone significantly inhibited PGE2 production by
||1. Periplocin has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used
||1. Apiin is the reducing and stabilizing agent. 2. Apiin has inhibitory activity in-vitro on iNOS expression and nitrite production when added before LPS stimulation in the medium
||1. Ingenol mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compoun
||Senkyunolide A is a useful standard compound for the quality evaluation and chemical differentiation between Rhizoma chuanxiong and Angelica sinensis, and suitable for the analysis
||1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.
||Epimedin A1(Hexandraside F) is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.
||7-O-MethylMangiferin is an xanthone isolated from the rhizomes of Iris nigricans.
||1. Swertianolin, mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. S
||Hosenkoside A has antimicrobial effect.
||Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.
||1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effe
||1. Deoxyshikonin may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular en
||D-DELTA-TOCOPHEROL is an isomer of Vitamin E,has antioxidant activity,and might be useful as effective ingredients in whitening cosmetics with lower skin toxicity.
||OSI-906 (Linsitinib) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib sel
||(±) Anabasine is a biphasic muscle relaxant.
||Clopamide is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
||Anidulafungin (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.
||Phosphorylcholine is an antigenic cell-surface component found on many commensal and pathogenic bacteria that reside in the upper airway.
||Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
||Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
||KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.
||Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
||NXY-059, a new-type nitrone, exhibits potently neuroprotective effects.
||Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).
||Tebipenem pivoxil, an orally activity carbapenem antibiotic, is utilized in treating otolaryngologic and respiratory infections.
||Vilazodone HCl，a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
||BAPTA-AM is a selective, permeable free calcium chelator.
||Ceftiofur Hydrochloride is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activ
||Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.
||Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
||Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.
||1-Hexadecanol, a fatty alcoholis, is utilized for making other chemicals.
||3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
||4μ8C(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.
||Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.
||Alibendol is a choleretic, antispasmodic, and cholekinetic.
||Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
||Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
||Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
||Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the therapy of cardiovascular diseases.
||Atracurium besylate is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on g
||Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
||Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
||Azomycin is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.
||Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
||Biapenem is a 1-beta-methylcarbapenem antibiotic with a wide range of antibacterial activity. Biapenem has similar antibacterial activity to that of imipenem, but is more stable ag
||CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).
||Bisacodyl is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation.
||Calcifediol(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
||Calcium Levofolinate, a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
||Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages
||Cefoselis is a widely used beta-lactam antibiotic.
||Cetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
||Chloroprocaine HCl is a local anesthetic during surgical procedures.
||Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced
||Clindamycin Hydrochloride inhibits protein synthesis by acting on the 50S ribosomal. It is the hydrochloride salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum
||Clindamycin palmitate HCl
||Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
||Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
||Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals.
||CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
||Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant.
||Dexrazoxane HCl is a cardio-protective drug.
||D-glutamine，an D type stereoisomer of glutamine， is one of the 20 amino acids which is encoded by the standard genetic code.
||Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
||Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative aerobic and anaerobic bacteria.
||Difluprednate(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.
||Dioscin is a saponin with antitumor activities.
||DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.
||Domiphen bromide is an antiseptic acting as a cationic surfactant.
||D-Pantothenic Acid is a water-soluble vitamin ubiquitously found in plants and animal tissues with an antioxidant property. Vitamin B5 is a component of coenzyme A (CoA) and a part
||Efaproxiral Sodium ，a synthetic allosteric modifier of hemoglobin， is utilized for brain metastases originating from breast cancer.
||Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
||Fenoprofen calcium hydrate
||Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).
||Fenticonazole Nitrate is an azole agent with antifungal activity.
||FPH1 (BRD-6125) can promote the expansion of iPS-derived hepatocytes.
||G-418 (disulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
||Grape Seed Extract
||Grape Seed Extract is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important
||Guanosine is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism.
||Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum.
||Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility, it is used as food additive and sieving matrix for DNA separations.
||Ibandronate sodium monohydrate
||Ibandronate is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
||Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.
||Isepamicin Sulphate， an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase， inhibits bacterial protein synthesis by targeting
||Isoconazole nitrate (Travogen) is an azole antifungal reagent.
||Isosorbide is a heterocyclic compound that is derived from glucose, used as a diuretic.
||L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.
||Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.
||Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
||L-Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
||Malotilate is a medicine used for the therapy of liver cirrhosis.
||Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.
||in clinically as an antihypertensive.
||Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
||Morin hydrate(Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).
||N6-Methyladenosine is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary n
||Nanchangmycin, a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals
||Nicaraven, a hydroxyl radical scavenger, has neuroprotective and antivasospastic effects.
||Oxacillin sodium monohydrate
||Oxacillin sodium monohydrate is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
||Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in hor
||Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
||Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and
||Ribitol is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
||Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
||<p>Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L.,
||SecinH3 is selective cytohesin inhibitor.
||Sertaconazole nitrate, a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.
||Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as t
||Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
||Sodium Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
||Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.
||STF-083010 is a selective inhibitor of the IRE1α endonuclease.
||Sulconazole Nitrate is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole nitrate inhibits fungal cytochrome P-450 ste
||TIC10 Isomer is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, super
||Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
||Troxipide, a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach
||Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
||Vanillin is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.Vanillin can reversibly and non-competitively inhibit t
||Zafirlukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.
||SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bond
||2-Deoxy-D-glucose is an analog of glucose, which is a glycolytic inhibitor with antiviral activity.
||4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of br
||Acetylcholine iodide is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and
||BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator.
||BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.
||Bromodeoxyuridine (BrdU), a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.
||CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0
||CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
||Carboxyfluorescein succinimidyl ester (CFSE) is a fluorescent cell staining dye. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecul
||Choline bitartrate is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acet
||Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
||Dp44mT，a effective iron chelator, has selective antitumor activity.
||Favipiravir (T-705), an effective and selective RNA-dependent RNA polymerase inhibitor, are applied to treat influenza virus infections.
||FCCP, a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes leading to disrupts ATP synthesis.
||NADP sodium salt
||NADP sodium salt is a coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions.
||HA15 targets specifically BiP/GRP78/HSPA5. HA15 exhibits anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resis
||Isosorbide mononitrate is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.
||L-Glutamic acid monosodium salt
||L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods.
||Lauric Acid，which is found naturally in various plant and animal fats and oils， is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coc
||LTX-315, the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.
||Pantoprazole Sodium is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal ce
||Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
||Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
||Imidacloprid is a systemic chloronicotinyl insecticide, which can be effectively used in agriculture to control pests .
||Nudifloric Acid is from Cordyceps bassiana. Nudifloric Acid targets to block AP-1-mediated luciferase activity, implying it has an anti-inflammatory function.
||Benzo[a]pyrene shows lung carcinogenicity in mice in a dose-dependent manner.
||Sodium Nitroprusside Dihydrate
||Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.
||Sodium Sulfadiazine is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.
||Sodium Tauroursodeoxycholate (TUDC)
||Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
||Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
||Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC
||1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats,in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig
||1. Chelerythrine may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has po
||1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of i
||1. Tuberstemonine exhibits relatively higher intestinal permeabilities. 2. Tuberstemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction.
||1. Genkwanin exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug
||1. Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
||1. Peimine has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB sign
||1. Sipeimine has antiasthmatic effect,on tracheal M receptor antagonist. 2. Sipeimine can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve to
||1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood̽brain barri
||Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
||1. Maackiain induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.
||1. Eriocitrin is powerful antioxidative flavonoid; (1) Prevents oxidative damages caused by acute exercise-induced oxidative stress.(2) Lipid-lowering effects in a rat model of hig
||1. Eriodictyol is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improvin
||1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocy
||1. Gycitein has weak estrogenic activity. 2. Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
||1. Pectolinarigenin exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eic
||1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
||1. Isocorynoxeine shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant n
||1. Isorhyncophylline and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hyperten
||1. Rhynchophylline can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can
||1. Orientin may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vas
||1. Flavokawain B has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic cons
||Sesamoside has antinociceptive activity.
||1. Phellodendrine has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.
||2''-Galloylhyperin found in Pyrola. It increases ruminal fiber fermentability by formed wall-bound lignin in primary maize cell walls.
||1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent f
||1. Astragalin may be a potential agent in the treatment of osteoarthritis. 2. Astragalin can be effective in allaying ROS-promoted bronchial fibrosis through inhibiting autophagoso
||1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner,2. Ruscogenin inhibited adhesion o
||1. Levistilide A inhibits liver fibrosis and angiogenesis.
||1. Nicotiflorin has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and
||1. Carnosol has anti-oxidative,anti-inflammatory,antiproliferative and apoptosis inducing properties. 2. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemot
||1. Oroxylin A has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6
||1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.
||1. Notopterol induces apoptosis and inhibits cell cycle-specific.
||1. Loganic acid and geniposide exhibit both sides effect on superoxide generation.
||1. Ginsenoside Rh4 could be safely used as adjuvant with low or non-haemolytic effect. 2. Ginsenoside Rh4 has cytotoxic activity and its aglycone against cancer cell lines.
||1. Ginsenoside Rk3 and Rh4 could have a role in treating inflammatory diseases. 2. Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic hea
||1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehyd
||1. Biotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation. 2. Aurantio-obtus
||1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent
||1. Monotropein has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition
||Notoginsenoside R2 has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathway
||1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberros
||1. Albiflorin has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantl
||1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Ir
||1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could
||1. Protosappanin B significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the
||1. Brazilin exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated
||Tenacissosides B, C, I and marsdenoside K inhibit the proliferation of Raji, NB4 and K562 cells in vitro significantly, in a dose and time dependent manner.
||Tenacissoside H has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
||1. Gomisin A may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways
||1. Schisantherin B shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
||1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-i
||Ginkgolic acid C17:1
||1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membrane
||Ginkgolic acid C15:1
||1. Ginkgolic acid C15:1 represses curli genes and prophage genes in EHEC.
||1. Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariec
||1. Epimedin B has potential activity against osteoporosis by stimulating osteoblasts.
||1. Spinosin ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activit
||Eupalinolide A has the effects of relieving phlegm and relieving cough, clearing away heat and detoxification, diuretic swelling and reducing blood pressure.
||Alisol A 24-acetate
||1. Alisol A 24-acetate has been determined for the quality control of this crude drug.
||Alisol B 23-acetate
||1. Alisol B 23-acetate produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acet
||1. Alismoxide has anti-inflammatory effects.
||1. Sweroside possesses strong hepatoprotective effect. 2. Sweroside is a promising osteoporosis therapeutic natural product, has anti-osteoporotic effect on the human MG-63 cells
||1. Cichoric acid has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. 2. Chico
||TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacok
||Qingyangshengenin is a steroid used in the preparation of antiepileptic agents.
||Eurycomanone is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibit
||1-Iodoadamantane is employed in the free-radical carbonylation reactions with alkenes.
||2,4-dihydroxybenzophenone (BP-1) can effectively protect C57BL/6J mice from APAP-induced hepatotoxicity. BP-1 has a protective effect on acute hepatotoxicity and neurotoxicity of m
||7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell m
||Dipalmitin has templating effects on soft palm mid fraction crystals.
||Herniarin is a natural coumarin with antitumor effect.
||During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria. It has also displayed antiox
||(2R, 3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel used to study the location of the binding sites. It shows cytotoxic,
||NA. Medical intermediate
||Oxymetholone is an anabolic androgenic steroid and synthetic derivative of testosterone. Formulations containing oxymetholone are used in the treatment of anemias caused by deficie
||2-Chloro-1,4-naphthoquinone is a substituted naphthoquinone which is used as an insecticide and acaricide.
||TBTA is a tertiary amine with three 1,2,3-triazole groups. It complexes with, and stabilizes, copper(I) to accelerate azide-alkyne cycloadditions, as used in click chemistry.
||Tris(2-carboxyethyl)phosphine hydrochloride may be employed as a catalyst for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It may be used as a reducing ag
||N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
||NADPH tetrasodium salt
||NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reaction
||Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functi
||Hexacosanoic acid, a very long-chain fatty acid, is related to adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
||BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.
||Gefarnate is a synthetic compound used for the treatment of gastric ulcers,and also used in the treatment of dry eye syndrome.
||Menaquinone-4 is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.
||Omberacetam is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compou
||TMB-PS is a chromogenic reagent for the detection of hydrogen peroxide e.g. in the enzymatic analysis of body fluids.
||Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae .
||Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects.
||Sapropterin dihydrochloride is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.
||Dimethocaine is a local anesthetic with reported stimulant properties most similar to cocaine.
||Sulfachloropyrazine sodium is an antiprotozoal,with antibacterial and anticoccidial effects
||Dinotefuran is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves d
||Hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine.
||Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a
||MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
||FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).
||Cephalosporin C zinc salt
||Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM), and this inhibition was largely attributable to the presence of zinc.
||Alagebrium Chloride is an advanced glycation end product (AGE) inhibitor, and has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patient
||BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .
||NSC139021 is a Rio2 kinase (RIOK2) inhibitor that inhibits ERG protein.
||Piperazine adipate is a potent broad spectrum anthelmintic.
||trans-trans-Muconic acid is a urinary metabolite of benzene.
||NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)
||Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
||IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)
||(2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor(IC50 : 126 nM).
||Diethyl phosphate, a Non-Specific Metabolite of Organophosphorus Pesticides.
||TPPU is a potent inhibitor of both human and mouse sEH (IC50 of 3.7 and 2.8 nM, respectively)
||Nelociguat(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.
||Guanosine 5'-diphosphate as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
||Demecarium bromide is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
||Prohydrojasmon is a synthesized plant gowth regulator, which has jasmonic acid activity.
||GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.
||5-Amino-2-chloropyridine is Pyridine intermediates
||Methuosis inducer 1
||Methuosis inducer 1 is a potent methuosis inducer, with nticancer activity.
||SMS2-IN-2 is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic
||Vasopressin acetate (113-79-1(free base))
||Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and
||EC330, a novel steroidal LIF inhibitor showed cytotoxicity in various cancer cell lines and NCI-60 cell line panel at low nano-molar range.
||Aramchol, also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and di
||Miridesap is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fl
||FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.
||beta-estradiol 17-acetate is a metabolite of estradiol.
||Vorasidenib is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
||Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
||AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis.
||Enclomiphene citrate is a non-steroidal estrogen receptor antagonist,with antioestrogenic property
||MBP146-78 is a potent and selective cGMP inhibitor dependent protein kinases.
||BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
||Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities
||C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
||Ursocholic acid, a bile acid found predominantly in bile of mammals.
||Trans-2-Decenoic acid is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees.
||L-2,3-diaminopropionic acid is an amino acid that is a precursor of antibiotics and staphyloferrin B a siderophore produced by Staphylococcus aureus.
||PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).
||SDMA is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).
||RSV-604 is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM)
||IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.
||(S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine.
||Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen
||NGI-1 is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability.
||2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
||Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.
||G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM)
||Toceranib phosphate, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR
||Substance P 1-7
||Substance P 1-7 is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalg
||RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity
||(S)-3-AMino-2-Methylpropanoic acid-HCl is a chemical compound.
||Meta-topolin, a highly active aromatic cytokinin from poplar leaves
||Thyrotropin-Releasing Hormone (TRH), Free Acid
||Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone lev
||All-trans-4-Oxoretinoic acid is an active metabolite of vitamin A.
||Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
||Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.
||1,4-Dichlorobenzene is a disinfectant, pesticide, and deodorant.
||2'-Hydroxy-2-methoxychalcone is a chemical compound.
||2-Phenylethylamine hydrochloride acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxid
||Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM
||3-(3-Hydroxyphenyl)propionic Acid is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.
||Cuminaldehyde is a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity,with a pleasant smell and contr
||4-Isopropylbenzyl alcohol is a natural product,with insecticidal effect.
||Acetophenone is an organic compound used as fragrances
||4-Hydroxyisoleucine has antidepressant-like, antidyslipidemic, and antihyperglycemic effects. It displays an insulinotropic activity.
||1-Phenyl-1,2-propanedione is a eukaryotic metabolite produced in plant metabolic reactions.
||2-Methoxycinnamaldehyde (2-MCA) is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.
||3-Hydroxycinnamic acid is a natual product isolated from Cinnamomum cassia Presl . 3-Hydroxycinnamic acid has antioxidant activity.
||4-Ethyloctanoic acid is a natural product isolated from Saussurea lappa Clarke,acts as food additive,Industrial perfume,and so on.
||Abametapir, a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
||2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis
||2,4-Dichlorophenol is the precursor to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D).
||2-Oxohexane is an ethereal tasting compound. Outside of the human body, 2-Oxohexane is found, on average, in the highest concentration within hyssops and milk (cow).
||3,3-Dimethylglutaric acid is a compound found in human urine.
||5-Bromocytosine can be used in the synthesis of cross-link products under anaerobic and aerobic conditions.
||Acid orange 7
||Acid orange 7 is a dye used to dye wool.
||α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB p
||Alendronic acid is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.
||6-Chloropurine is a building block in chemical synthesis,with Antitumor activities.
||Ademetionine is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
||AS057278 is an D-amino acid oxidase (DAAO) inhibitor.
||Argireline, a synthetic peptide, which is patterned from the N-terminal end of the protein SNAP-25, can both reduce the degree of existing facial wrinkles and demonstrate effective
||2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).
||Ambroxide is a naturally product,is one of the key constituents of ambergris.
||1-Undecanol is a natural product in many foods such as fruits, butter, eggs and cooked pork, is used as a flavoring ingredient.
||2-Hydroxycaprylic acid belongs to the class of organic compounds known as medium-chain fatty acids.
||6-Bromo-2-hydroxy-3-methoxybenzaldehyde is an inhibitor of IRE-1α (IC50 : 0.08 μM).
||Methasulfocarb is a fungicide, bactericide compound.
||Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
||γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is the substrate of CRF21 (gamma-Glutamylcyclotransferase, GGCT).
||Tiadinil, a plant activator of systemic acquired resistance, boosts the production of herbivore-induced plant volatiles.
||2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI Oxidation contributes to antibiotic lethality in stationary-phase mycobacteria.
||Guanidinosuccinic acid (GSA) has been identified as a uremic toxin, is a nitrogenous metabolite isolated in excess from serum and urine.
||3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-enoate is a chemical compound
||Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.
||Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.
||Teriflunomide is the principal active metabolite of leflunomide, an approved therapy for rheumatoid arthritis and multiple sclerosis.
||3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-acti
||H-Leu-Leu-Ome.HCl is a compound
||Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.
||Tetraethylammonium chloride (TEAC) is a quaternary ammonium compound.
||Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
||6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme.
||voxelotor is an inhibitor of sickle hemoglobin (HbS)
||Afamelanotide is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.
||Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
||Vanillic acid is used as a condiment in food，which used in wine and vinegar. It is an intermediate in the production of vanillin from ferulic acid.
||N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC), also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker.
||Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
||Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.
||Pertuzumab (anti-HER2), a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2 to bind to other m
||Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM.
||Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastat
||Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
||Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
||Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
||Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
||Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells.
||Alemtuzumab is a humanized monoclonal antibody against CD52, an antigen found on the surface of normal and malignant lymphocytes.
||Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9).
||Obinutuzumab (GA101) a novel glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.
||Ofatumumab is a fully human monoclonal antibody to CD20, which appears to inhibit early-stage B lymphocyte activation
||Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE)
||Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
||Secukinumab is a fully humanized, monoclonal anti-IL-17A antibody, and the first in its class to be approved by the US Food and Drug Administration for the treatment of moderate to
||Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect,and it can improve cardiac function of patients and improve
||Used in perfumery and food flavouring.
||5-Methylfurfural has been identified as one of the volatile flavor compounds in tamarind, Dutch Coffee, barrel-aged wines and deep fat-fried soybeans.
||trans-4-Phenyl-3-buten-2-one is used in various synthetic preparations.
||Used in soap perfumes.
||2’-Hydroxyacetophenone is a phenolic compound used in the synthesis of potential anti-myobacterial and anticancer agents.
||Perfumery and flavouring ingredient.
||1. Evodine has antinociceptive activity.
||Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
||1. Anti-infective, anti-cancer, enhance immunity 2. Skin moisturizing and delaying skin aging 3. Nutritional supplement
||Alanine is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans, Alanine is one of the most widely used for p
||Methionine is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. Methionine is found in meat, fish, and dairy products. It plays an important
||Used in the synthesis of N-(D-galacturonoyl) amino acids and dipeptides.
||1. Acevaltrate displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1
||Maltopentaose is a maltooligosaccharide that is used for research and diagnostic purposes. They can also be used in nutrients and healthcare.
||Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (Areca catechu). It i
||5,7-Dihydroxy-4-methylcoumarin inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property.
||Growth inhibition of human U937 cells by [3H]thymidine incorporation assay
||The combination of Valproic acid with coumarin-3-carboxylic acid suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways
||7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist.
||7,8-Dihydroxy-4-phenylcoumarin inhibits the activity of Staphylococcus aureus DNA helicase
||1. Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.
||Plantagoside is a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50: 5 μM). It also is a potent inhibitor of the Maillard reaction.
||1. Dalbergin exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin preve
||Calenduloside E exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by inhibiting glucose transport at the brush bor
||1. Chrysosplenetin is a metabolic inhibitor of artemisinin.
||Cyclen is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.
||Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic sy
||Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia.
||FERULIC ACID METHYL ESTER
||Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activiti
||(-)-3,5-Dicaffeoyl quinic acid
||3,5-Dicaffeoylquinic acid is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giar
||Coniferin has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin anal
||Deapi-platycodin D3 is a natural product isolate from the root of Platycodon grandiflorum.
||Arenarioside is a natural product, and GI50 values of 10-16 microM against B16F10 cell.
||Parishin C is a phenolic glycoside and a major component of G. elata, have antioxidant property
||5'-UMP disodium salt
||Uridine 5′-monophosphate disodium salt has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used t
||Gibberillic acids (GA) are important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division a
||Inhibition of inosine and alanine-induced germination of Bacillus anthracis Sterne spore pre-incubated for 15 mins.
||A constituent of nucleic acids. It was isolated from yeast nucleic acid.
||Anthraquinones are the main active constituents in herbs often used to relieve constipation.
||1-Naphthaleneacetic Acid, is widely used in agriculture for various purposes. It is a synthetic plant hormone in the auxin family and is an ingredient in many commercial plant root
||It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
||1. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemotherapeutic agent for th
||Sequoyitol, a methyl derivative of inositol, is often used to treat diabetes.
||5'-IMP disodium salt
||A flavor agent.
||Naringenin is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promote
||Zeatin is a cytokinin derived from adenine. Zeatin was discovered in immature corn kernels from the genus Zea. It promotes growth of lateral buds and when sprayed on meristems stim
||Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
||Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow
||(1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one also known by its common name as (-)-Camphor is a chiral intermediate of camphor and is used as a flavour additive in foods and sw
||Sodium taurocholate hydrate
||Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic a
||Tripalmitin is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a diet
||One of the pyrimidine bases of living matter. Derivation: Hydrolysis of deoxyribonucleic acid, from methylcyanoacetylurea by catalytic reduction. Use: Biochemical research. Thymine
||2-Adamantanol was used to synthesize antiallergic drug Mizolastine.
||1. Thymidine overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
||Cannabidiol is GPR55 and weak CB1 antagonist (IC50s: 0.445 and 3.35 μM), CB2 receptor inverse agonist and inhibitor of anandamide uptake (IC50: 27.5 μM). It also a weak agonist a
||Aristolone has potential anti-cancer activity.
||Angelic Anhydride is a reagent in the improved synthesis of angelate esters, which are the active chemical behind the strong pain-relieving and spasmolytic action of extracts from
||1. Incensole has a protective or stimulating effect on β-cells of the rat pancreas, it also can increase the insulin secretion, which evidenced by a significant increase both in b
||Antitussive, antiasthmatic, hypoglycemic, anti - tumor, treatment of gout.