Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sodium Tetradecyl Sulfate 是洗涤剂硬化剂,常用于静脉曲张及食管静脉的治疗。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 282 | 现货 | ||
50 mg | ¥ 434 | 现货 | ||
100 mg | ¥ 654 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 195 | 现货 |
产品描述 | Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins. |
体外活性 | Proteins C, S and antithrombin (AT) were assayed in normal plasma treated with increasing concentrations of Sodium Tetradecyl Sulfate. High concentration (>0.6%) Sodium Tetradecyl Sulfate significantly destroyed proteins C, S and AT. Sodium Tetradecyl Sulfate potentiated the anticoagulant effect of APC. Sodium Tetradecyl Sulfate mimicked AT and demonstrated significant anti-Xa and anti-IIa activity. STS demonstrated a weak anticoagulant profile to heparin. It also significantly potentiated the anticoagulant effect of heparin[2]. |
体内活性 | i.v. + p.v. injection of Sodium Tetradecyl Sulfate and hydroxy polyethoxy dodecan provided a high degree of efficacy as regards vein occlusion. On the other hand, i.v. + p.v. injection induced a severe inflammation and necrosis of the tissues surrounding the sclerosed vein[3]. |
分子量 | 317.44 |
分子式 | C14H30NaO4S |
CAS No. | 1191-50-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL (204.76 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.1502 mL | 15.751 mL | 31.502 mL | 78.755 mL |
5 mM | 0.63 mL | 3.1502 mL | 6.3004 mL | 15.751 mL | |
10 mM | 0.315 mL | 1.5751 mL | 3.1502 mL | 7.8755 mL | |
20 mM | 0.1575 mL | 0.7876 mL | 1.5751 mL | 3.9378 mL | |
50 mM | 0.063 mL | 0.315 mL | 0.63 mL | 1.5751 mL | |
100 mM | 0.0315 mL | 0.1575 mL | 0.315 mL | 0.7876 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Sodium Tetradecyl Sulfate 1191-50-0 Others Inhibitor Tetradecyl sulfate varicose veins inhibit sclerosing agent inhibitor