Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antifungal agent 38 是一种环二硫化物,具有抗真菌和抗细菌活性。Antifungal agent 38 能诱导菌丝收缩,破坏质膜的完整性,并导致细胞内容物的破坏和渗漏。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 10,600 | 10-14周 | ||
50 mg | ¥ 13,800 | 10-14周 | ||
100 mg | ¥ 17,500 | 10-14周 |
产品描述 | Antifungal agent 38 is a geterocyclic disulfide with antifungal and antibacterial activity. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents [1]. |
体外活性 | Antifungal agent 38 (50 μg/mL) has anti-fungal activity against 10 pathogenic fungi with inhibition rates of 56.57% ( R. solani ), 100% ( S. sclerotiorum ), 55.09% ( B. cinerea ), 71.23% ( F. graminearum ), 37.32% ( M. oryzae ), 50.87% ( P. capsici ), 100% ( A. flavus ), 59.75% ( P. expansum ), 100% ( M. fructicola ), 65.78% ( R. stolonifer ), respectively [1]. Antifungal agent 38 (5 μg/mL) damages plasma membrane integrity of M. fructicola [1]. Antifungal agent 38 (100 μg/mL) displays excellent anti-bacterial activity against X. oryzae accc 11602, X. axonpodis [1]. Antifungal agent 38 inhibits fungus growth with EC 50 s of 17.09 μg/mL ( R. solani ), 6.34 μg/mL ( S. sclerotiorum ), 25.24 μg/mL ( F. graminearum ), >10 μg/mL ( A. flavus ), 10.42 μg/mL ( M. fructicola ), 45.71 μg/mL ( B. cinerea ), respectively [1]. Cell Viability Assay [1] Cell Line: M. fructicola Concentration: 10, 25, 50 μg/mL Incubation Time: 2, 4, 6 days Result: Inhibited M. fructicola growth. |
体内活性 | Antifungal agent 38 (compound S8) (200 μg/mL) shows equivalent curative and higher protective effects as the positive drug Thiophanate-Methyl in vivo [1]. Antifungal agent 38 (50, 100, 200 μg/mL, 30 mL; sprinkling) applies on pears and inhibits M. fructicola growth in vivo [1]. |
分子量 | 200.32 |
分子式 | C8H12N2S2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Antifungal agent 38 Inhibitor inhibitor inhibit