Powder: -20°C for 3 years | In solvent: -80°C for 1 year
6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 1,120 | 35日内发货 | ||
5 mg | ¥ 4,900 | 35日内发货 | ||
10 mg | ¥ 8,690 | 35日内发货 |
产品描述 | 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2. |
别名 | 6β-Prostaglandin I1 |
分子量 | 354.487 |
分子式 | C20H34O5 |
CAS No. | 62770-50-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMF: >10 (from 6b-PGI1)
DMSO: >5 (from 6b-PGI1)
PBS (pH 7.2): >80 μg (from 6b-PGI1)
Ethanol: >20 mg/mL (from 6b-PGI1)
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
6β-Prostaglandin I1 62770-50-7 6β Prostaglandin I1 6β-Prostaglandin I-1 6b-Prostaglandin I1 6βProstaglandin I1 6beta-Prostaglandin I1 Inhibitor inhibitor inhibit