Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hydroquinine 是金鸡纳生物碱,可用于制备衍生物(如 C9 脱氢喹啉、9-乙酰氧基-10,11-二氢喹、 10,11-二氢喹单盐酸盐等)。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 mg | ¥ 150 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 100 | 现货 |
产品描述 | Hydroquinine, is an organic compound and as a cinchona alkaloid closely related to quinine. |
体内活性 | Compared with placebo the decrease in the mean number of muscle cramps (16.1 or 58%) in the active drug treatment group during the medication period was highly significant (Wilcoxon test p = 0.004).Daily dose of 300 mg hydroquinine hydrobromide was effective in preventing frequent ordinary muscle cramp in healthy female volunteers. The effects of hydroquinine outlasted its administration. The drug was well tolerated. |
动物实验 | Twenty healthy adult volunteers experiencing at least 3 muscle cramps a week (6 men, 14 women aged 38-78 yrs) were enrolled into this study, and 19 of them completed it. Hydroquinine hydrobromide (300 mg/day) was administered to group 1 (10 women) and placebo to group 2 (4 women, 6 men). The frequency, severity, duration and location of muscle cramps as well as short-term adverse drug effects were recorded in daily diaries. |
别名 | 氢化奎宁, dihydroquinine |
分子量 | 326.43 |
分子式 | C20H26N2O2 |
CAS No. | 522-66-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/mL (199.12 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 3.0634 mL | 15.3172 mL | 30.6344 mL | 76.5861 mL |
5 mM | 0.6127 mL | 3.0634 mL | 6.1269 mL | 15.3172 mL | |
10 mM | 0.3063 mL | 1.5317 mL | 3.0634 mL | 7.6586 mL | |
20 mM | 0.1532 mL | 0.7659 mL | 1.5317 mL | 3.8293 mL | |
50 mM | 0.0613 mL | 0.3063 mL | 0.6127 mL | 1.5317 mL | |
100 mM | 0.0306 mL | 0.1532 mL | 0.3063 mL | 0.7659 mL |
中药材名称 | 中药材拉丁名 | 性 | 味 | 归经 |
金鸡纳 | Cinchona calisaya Weddell | 寒 | 苦 |
方剂名称 | 处方组成 | 剂型 | 处方来源 |
疟疾五神丹 | 姜半夏,川贝母,青皮,青蒿,金鸡纳 | 丸剂 | 《湿温时疫治疗法》引何廉臣方。 |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Hydroquinine 522-66-7 Others inhibit 氢化奎宁 dihydroquinine Inhibitor inhibitor