Powder: -20°C for 3 years | In solvent: -80°C for 1 year
p-cumylphenol 可治疗新生大鼠肾小管囊肿形成。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 112 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 195 | 现货 |
产品描述 | p-cumylphenol can treat R enal Tubular Cyst Formation in Newborn Rats. |
体内活性 | P-cumylphenol induced multiple renal cysts that developed in the collecting ducts of the outer medulla in neonatal rats, and it is suggested that epithelial cell proliferation may play some roles in the induction of cystic lesions. |
动物实验 | Fifteen animals per sex were treated orally with 300 mg/kg/day of p-cumylphenol for up to 18 days from postnatal day (PND) 4 and were sacrificed on PNDs 8, 12, 19 and 22 and after a 7 day recovery period. On PNDs 8 and 12, slight dilatation of the collecting ducts was frequently observed in the medulla and slight papillary necrosis was also noted in some cases. These dilated collecting ducts were lined with slightly hyperplastic epithelial cells. On PNDs 19 and 22, multiple large cystic changes arising from the collecting ducts in the outer medulla were seen. |
分子量 | 212.29 |
分子式 | C15H16O |
CAS No. | 599-64-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (105.99 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 4.7105 mL | 23.5527 mL | 47.1054 mL | 117.7634 mL |
5 mM | 0.9421 mL | 4.7105 mL | 9.4211 mL | 23.5527 mL | |
10 mM | 0.4711 mL | 2.3553 mL | 4.7105 mL | 11.7763 mL | |
20 mM | 0.2355 mL | 1.1776 mL | 2.3553 mL | 5.8882 mL | |
50 mM | 0.0942 mL | 0.4711 mL | 0.9421 mL | 2.3553 mL | |
100 mM | 0.0471 mL | 0.2355 mL | 0.4711 mL | 1.1776 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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