Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antibacterial Agent 58 (AA58) is a potent antibacterial compound that effectively reduces the minimum inhibitory concentration (MIC) value of Ceftazidime, another antibacterial agent.
产品描述 | Antibacterial Agent 58 (AA58) is a potent antibacterial compound that effectively reduces the minimum inhibitory concentration (MIC) value of Ceftazidime, another antibacterial agent. |
体外活性 | Antibacterial agent 58 (example 23) significantly lowers MIC value of Ceftazidime (MIC=1, 2, 8 mcg/ml for E. coli NCTC 1335 1, E. coli M50, and E. coli 7MP, respectively). Antibacterial agent 58 significantly lowers MIC values of the antibacterial agent Ceftazidime (MIC=0.2~2 mcg/ml for class A ESBL; 2-8 mcg/ml for class C ESBL; 4-8 mcg/ml for KPC ESBL)[1]. From WO2013030735A1, example 23. Class A ESBL: E.coli W 13353; E.coli W3351; E.coli W 13352 Class C ESBL: E.coli M 50; E.coli 7 MIP; E.coli B 89 KPC ESBL: K.pneumoniae H 520; K.pneumoniae H 521; K. pneumoniae H 522 Class D ESBL: A.Baumannii13301; A.baumannii 13304 |
分子量 | 327.27 |
分子式 | C8H12N6NaO5S |
CAS No. | 1426572-65-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Antibacterial agent 58 1426572-65-7 Inhibitor inhibitor inhibit