keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate (96249-43-3 Free base)) 存在于细胞表面,通过与其特异性配体的结合而被激活。EGFR 属于受体酪氨酸激酶(RTK) 的 ErbB 家族。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 343 | 现货 | ||
2 mg | ¥ 491 | 现货 | ||
5 mg | ¥ 997 | 现货 | ||
10 mg | ¥ 1,760 | 现货 | ||
25 mg | ¥ 2,480 | 现货 | ||
50 mg | ¥ 3,730 | 现货 | ||
100 mg | ¥ 5,360 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,580 | 现货 |
产品描述 | Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK). |
体外活性 | This autophosphorylation elicits downstream activation and signaling by several other proteins that associate with the phosphorylated tyrosines through their own phosphotyrosine-binding SH2 domains.?These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, which lead to DNA synthesis and cell proliferation.Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.?Activation of the receptor is important for the innate immune response in human skin.? |
别名 | Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base) |
分子量 | 1436.52 |
分子式 | C63H97N13O25 |
CAS No. | T21723L |
keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mg/mL (7.27mM)
DMSO: 133mg/mL(96.62mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O / DMSO | 1 mM | 0.6961 mL | 3.4806 mL | 6.9613 mL | 17.4032 mL |
5 mM | 0.1392 mL | 0.6961 mL | 1.3923 mL | 3.4806 mL | |
DMSO | 10 mM | 0.0696 mL | 0.3481 mL | 0.6961 mL | 1.7403 mL |
20 mM | 0.0348 mL | 0.174 mL | 0.3481 mL | 0.8702 mL | |
50 mM | 0.0139 mL | 0.0696 mL | 0.1392 mL | 0.3481 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Epidermal Growth Factor Receptor Peptide Acetate T21723L Others Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base) Inhibitor inhibitor inhibit