Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ubiquinol is a reduced form of coenzyme Q10 (CoQ10) and is a potent antioxidant that has the capacity to protect Vitamin E.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 μg | ¥ 2,110 | 35日内发货 | ||
1 mg | ¥ 3,810 | 35日内发货 | ||
5 mg | ¥ 16,800 | 35日内发货 | ||
10 mg | ¥ 29,400 | 35日内发货 |
产品描述 | Ubiquinol is a reduced form of coenzyme Q10 (CoQ10) and is a potent antioxidant that has the capacity to protect Vitamin E. |
体外活性 | The lipophilic environment encircles the lipophilic low-molecular-weight antioxidants (α-tocopherol, β-carotene, and Ubiquinol) and prevents them from reacting as skin protectors[1]. |
体内活性 | The levels of these homologues are highest in heart with lesser amounts occurring in kidney, liver and other organs. In liver and blood plasma, the UQred homologue amounted to 70-80% of the total UQ (UQox + Ubiquinol = t-UQ). Ubiquinol is less than 30% of t-UQ in other tissues and blood cells. t-UQ is much higher in leukocytes and platelets in blood than in erythrocytes. In erythrocytes, t-UQ is exclusively located in the cell membranes.Ubiquinol is also found in all subcellular components isolated from the liver and kidney, and its ratio is approximately the same as the ratio of ubiquinol/t-UQ in the entire organ. The levels of Ubiquinol per mg protein in subcellular fractions from liver is highest in mitochondria, with lesser amounts present in plasma membranes, lysosomes, Golgi complex, nuclei, microsomes and cytosol. In the mitochondria, the outer membranes are richer in t-UQ than the inner membranes[4]. |
别名 | Ubiquinol-10, CoQH2-10 |
分子量 | 865.381 |
分子式 | C59H92O4 |
CAS No. | 992-78-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Ubiquinol 992-78-9 Others Ubiquinol-10 CoQH2-10 Inhibitor inhibitor inhibit