Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 13,900 | 8-10周 | ||
50 mg | ¥ 18,300 | 8-10周 | ||
100 mg | ¥ 23,500 | 8-10周 |
产品描述 | Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively. |
别名 | FddClUrd, 935U-83, FCU, DRG-0215, BW-935U-83 |
分子量 | 264.64 |
分子式 | C9H10ClFN2O4 |
CAS No. | 119644-22-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
H2O: 50mg/ml(446mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 3.7787 mL | 18.8936 mL | 37.7872 mL | 94.468 mL |
5 mM | 0.7557 mL | 3.7787 mL | 7.5574 mL | 18.8936 mL | |
10 mM | 0.3779 mL | 1.8894 mL | 3.7787 mL | 9.4468 mL | |
20 mM | 0.1889 mL | 0.9447 mL | 1.8894 mL | 4.7234 mL | |
50 mM | 0.0756 mL | 0.3779 mL | 0.7557 mL | 1.8894 mL | |
100 mM | 0.0378 mL | 0.1889 mL | 0.3779 mL | 0.9447 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Raluridine 119644-22-3 FddClUrd 935U-83 FCU DRG0215 DRG 0215 DRG-0215 BW-935U-83 Inhibitor inhibitor inhibit