Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T5S0983 | Absinthin
洋艾素
|
1362-42-1 |
|
|
Absinthin (Absynthin) 是结构独特的三萜类化合物,是艾草苦味高的原因。它是苦味受体hTAS2R46的激动剂,它利用 hTAS2R46 介导的受体特异性机制抑制组胺诱导的细胞内 Ca2+升高。 | ||||
TN2186 | Schisantherin D
五味子酯 D
|
64917-82-4 | 98% |
|
Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110. | ||||
T14208 | AMD 3465
化合物 T14208
|
185991-24-6 | 98% |
|
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) i... | ||||
T16829 | (S)-BI-1001
化合物 T16829
|
957889-73-5 | 98% |
|
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM). | ||||
T78737 | NNRTIs-IN-3
化合物 NNRTIs-IN-3
|
98% |
|
|
NNRTIs-IN-3(化合物8)作为一种HIV-1非核苷逆转录酶抑制剂,表现出较高的效力(EC50=0.01 µM)。 | ||||
T78950 | HIV-1 protease-IN-8
化合物 HIV-1 protease-IN-8
|
2925287-55-2 | 98% |
|
HIV-1protease-IN-8(compound 34b)是一款高效的HIV-1蛋白酶抑制剂,其IC50为0.32 nM。该化合物对野生型HIV-1(HIV-1NL4-3)及耐药变体(HIV-1MDR)的IC50分别为0.29 μM与1.90 μM,表明其对这两种型别均展现出显著的抗病毒效果。 | ||||
T79295 | HIV-1 protease-IN-9
化合物 HIV-1 protease-IN-9
|
2925381-27-5 | 98% |
|
HIV-1protease-IN-9 (compound 5b)为HIV-1蛋白酶抑制剂,具有0.028 nM的Ki值和66.8 nM的IC50,表现出显著的抗病毒活性。 | ||||
T79536 | HIV-1 protease-IN-11
化合物 HIV-1 protease-IN-11
|
2925287-54-1 | 98% |
|
HIV-1protease-IN-11 (compound 34a) 为一抗HIV-1蛋白酶抑制剂,其IC50值为0.41 nM,并对抗耐药变异表现出显著活性。 | ||||
T79537 | HIV-1 protease-IN-12
化合物 HIV-1 protease-IN-12
|
2925287-59-6 | 98% |
|
HIV-1protease-IN-12 (compound 35b)为HIV-1蛋白酶抑制剂,具有0.51 nM的IC50值,同时对HIV耐药变体也具有抑制作用。 | ||||
T79953 | Acetyl-binankadsurin A
化合物 Acetyl-binankadsurin A
|
77174-33-5 | 98% |
|
Acetyl-binankadsurin A(化合物5)是从南五味子(Kadsura longipedunculata)中提取的一种木脂素。该化合物对HIV-1蛋白酶表现出较低的抑制活性,其半抑制浓度(IC50)超过100 μg/mL。 | ||||
T80112 | Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2
化合物 Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2
|
130877-92-8 | 98% |
|
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 是一种用于检测HIV-1蛋白酶活性的荧光底物。 | ||||
TN4347 | Jacoumaric acid
化合物 TN4347
|
63303-42-4 | 98% |
|
Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor. | ||||
TN3567 | Calanolide E
化合物 TN3567
|
142566-61-8 | 98% |
|
Calanolide E2 has anti-HIV activity. | ||||
TN4433 | Licoarylcoumarin
化合物 TN4433
|
125709-31-1 | 98% |
|
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE st... | ||||
TN5243 | Vitexilactone
化合物 TN5243
|
61263-49-8 | 98% |
|
Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse trans... | ||||
T2S0605 | Liquidambaric lactone
路路通内酯
|
185051-75-6 | 98% |
|
Liquidambaric lactone 是一种分离自Euonymus grandiflorusWall 中的化合物。 | ||||
TN1767 | InteriotherinA
内南五味子酯A
|
181701-06-4 | 98% |
|
Interiotherin A inhibits HIV replication with the EC50 value of 3.1 micrograms/mL. | ||||
TN1235 | 3,4,5-Tricaffeoylquinic acid
3,4,5-三咖啡酰奎宁酸
|
86632-03-3 | 98% |
|
3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like rece... | ||||
TN4820 | Pre-schisanartanin B
化合物 TN4820
|
1033288-92-4 | 98% |
|
Pre-schisanartanin B has cytotoxicity, it also has anti-HIV-1 activity. | ||||
TN5011 | Shizukaol B
化合物 TN5011
|
142279-40-1 | 98% |
|
Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinfl... |