Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PMEDAP 是有效的人类免疫缺陷病毒 (HIV) 复制抑制剂。它具有抗小鼠巨细胞病毒活性。它有效抑制莫罗尼鼠肉瘤病毒诱导的肿瘤形成和相关死亡率。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 473 | 现货 | ||
2 mg | ¥ 688 | 现货 | ||
5 mg | ¥ 1,110 | 现货 | ||
10 mg | ¥ 1,880 | 现货 | ||
25 mg | ¥ 3,180 | 现货 | ||
50 mg | ¥ 4,660 | 现货 | ||
100 mg | ¥ 6,630 | 现货 | ||
500 mg | ¥ 13,300 | 6-8周 |
产品描述 | PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP also has anti-murine cytomegalovirus (MCMV) activity. |
体内活性 | In Three-week-old male NMRI mice inoculated with MSV, PMEDAP (0.25-5 mg/kg; IP; daily;) effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice. PMEDAP also suppressed tumor formation and mortality in a dose-dependent manner[2]. |
分子量 | 288.2 |
分子式 | C8H13N6O4P |
CAS No. | 113852-41-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
0.1 M NaOH: 14.29 mg/mL (49.58 mM), when pH is adjusted to 12 with NaOH. Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
0.1 M NaOH | 1 mM | 3.4698 mL | 17.3491 mL | 34.6981 mL | 86.7453 mL |
5 mM | 0.694 mL | 3.4698 mL | 6.9396 mL | 17.3491 mL | |
10 mM | 0.347 mL | 1.7349 mL | 3.4698 mL | 8.6745 mL | |
20 mM | 0.1735 mL | 0.8675 mL | 1.7349 mL | 4.3373 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
PMEDAP 113852-41-8 Microbiology/Virology Others Proteases/Proteasome HIV Protease sarcoma replication CMV Inhibitor HIV inhibit mice Human immunodeficiency virus Cytomegalovirus mortality virus inhibitor