JAK/STAT信号通路

账户密码登录
手机快捷登录

用户名：

密码：

还没有陶术账户？去注册忘记密码

手机号码：

验证码：

还没有陶术账户？去注册忘记密码

手机号码：

验证码：

密码：

6~16个字符、区分大小写、必须包含字母和数字

确认密码：

点击查看陶术生物会员政策及相关条款

手机号码：

验证码：

新密码：

6~16个字符、区分大小写、必须包含字母和数字

确认密码：

密码已经重置成功，快去使用新密码吧！
登录账号

记住密码忘记密码？

6~16个字符、区分大小写、必须包含字母和数字

点击查看陶术生物会员政策及相关条款

6~16个字符、区分大小写、必须包含字母和数字

密码已经重置成功，快去使用新密码吧！登录账号

The JAK-STAT signalling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death and tumour formation. The pathway communicates information from chemical signals outside of a cell to the cell nucleus, resulting in the activation of genes through a process called transcription. There are three key parts of JAK-STAT signalling: Janus kinases (JAKs), signal transducer and activator of transcription proteins (STATs), and receptors (which bind the chemical signals).Disrupted JAK-STAT signalling may lead to a variety of diseases, such as skin conditions, cancers, and disorders affecting the immune system. Currently, several JAK-targeting drugs have been used in the clinic for treating diseases including rheumatoid arthritis and myeloproliferative.