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Prolyl Endopeptidase (PREP)

Prolyl endopeptidase (PE) also known as prolyl oligopeptidase or post-proline cleaving enzyme is an enzyme that in humans is encoded by the PREP gene. Prolyl endopeptidase is a large cytosolic enzyme that belongs to a distinct class of serine peptidases. It was first described in the cytosol of the rabbit brain as an oligopeptidase, which degrades the nonapeptide bradykinin at the Pro-Phe bond. The enzyme is involved in the maturation and degradation of peptide hormones and neuropeptides.

Cat. No.	Product Name	CAS No.	Purity
T78619	Z-Pro-Pro-CHO 化合物 Z-Pro-Pro-CHO	108708-25-4	98%
T78619	Z-Pro-Pro-CHO为一种有效的脯氨酰寡肽酶抑制剂，其具有针对人类及曼氏血吸虫脯氨酰寡肽酶的较低半抑制浓度（IC50），分别为0.16 μM和0.01 μM。
T80106	Z-Pro-Pro-aldehyde-dimethyl acetal 化合物 Z-Pro-Pro-aldehyde-dimethyl acetal	170116-63-9	98%
T80106	Z-Pro-Pro-aldehyde-dimethyl acetal 是一种高效的脯氨酸内肽酶(PRE P)抑制剂，其IC50值为12 nM。该化合物在衰老过程和神经退行性疾病，诸如阿尔茨海默病中认知功能障碍的研究中具有重要作用。
TN4442	Linderene acetate 乌药醇乙酸酯	26146-28-1	99.75%
TN4442	Linderene acetate 是一种脯氨酸肽链内切酶抑制剂，分离自Lindera strychnifolia 中。
T35233	Y-29794 Tosylate 化合物Y-29794 Tosylate	143984-17-2	99.10%
T35233	Y-29794 Tosylate (Y-29794) 是一种具有口服活性、有效且特异性的非肽脯氨酰内肽酶 (PPCE) 抑制剂。