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CXCR
T1739 WZ811 WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).
T1776 Plerixafor Plerixafor, a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
T1776L AMD 3100 octahydrochloride AMD 3100 octahydrochloride blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bo
T1955 SB225002 SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
T2477 UNBS-5162 UNBS-5162 is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.
T3047 SRT3109 SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.
T3327 Arteether Arteether is a new, fast-acting antimalarial drug.
T3396 Baohuoside I Baohuoside I is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.
T4032 MSX-127 MSX-127 elicites positive response in peptide CXCR4.
T4033 MSX-130 MSX-130 is CXCR4 Antagonist.
T4163 Repertaxin Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxi
T6764 ATI-2341 ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of
T3992 MSX-122 MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).
T5193 Danirixin Danirixin is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).
T5207 LIT-927 LIT-927 is an orally active CXCL12 neutraligand (Ki: 267 nM for CXCL12 binding to CXCR4).
T7130 Navarixin Navarixin(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, cha
T5849 JMS-17-2 JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
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