目录号 | 产品详情 | 靶点 | |
---|---|---|---|
TP1835L | Endogenous Metabolite | ||
Enterostatin, human, mouse, rat acetate 是一种五肽,主要由分泌的胰腺前脂肪酶在肠道中形成。 | |||
TP1188L | Somatostatin | ||
Cortistatin 14, human, rat acetate 是一种与 somatostatin-14 结构相似的神经肽,具有抗惊厥、神经保护作用和显着的抗炎特性。 Cortistatin 14, human, rat acetate 通过与生长抑素受体结合并发挥其功能。 | |||
TP1453 | Others | ||
Tau protein (592-597), Human TFA 是人 Tau 蛋白的肽片段。 | |||
TP1155L | GHSR | ||
Human growth hormone-releasing factor acetate 是一种下丘脑多肽,通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。 | |||
T36926L | Others | ||
Neuropeptide SF (human) aceate 是一种神经肽,可增强心室旁 CRH 的释放并增加血浆中的 ACTH 和皮质酮水平。 | |||
TP1116L | Neurotensin Receptor | ||
Kinetensin acetate(103131-69-7 free base) 是从经胃蛋白酶处理的人血浆中分离出来的。它是一种神经降压素样肽。 | |||
TP1325L | Others | ||
Gastrin-Releasing Peptide, human(TFA) (93755-85-2 free base) 是一种调节性人类肽,可引发胃泌素释放并调节胃酸分泌和肠道运动功能。支配胃G 细胞的迷走神经节后纤维释放GRP,刺激G 细胞释放胃泌素。 | |||
TP2312 | Others AMPK | ||
MOTS-c(Human) Acetate(1627580-64-6 free)是一种线粒体衍生肽。 它诱导 AMP 类似物 AICAR 的积累,增加 AMPK 的激活和其下游 GLUT4 的表达。它可诱导葡萄糖摄取并提高胰岛素敏感性。 它对调节肥胖、糖尿病、运动和长寿有重要意义。 | |||
T76792 | Others | ||
Sibrotuzumab (BIBH 1) 是一种靶向成纤维细胞激活蛋白 (FAP)的人源化 IgG1 单克隆抗体。Sibrotuzumab 可用于研究结直肠癌和非小细胞肺癌。 | |||
TP1345 | GPR Kisspeptin | ||
Kisspeptin-10, human (TFA)(374675-21-5,FREE) 是一种有效的血管收缩剂和血管生成抑制剂。 Kisspeptin-10,人类 TFA 通过其受体 GPR54 充当肿瘤转移抑制因子。 Kisspeptin-10-GPR54系统在胚胎肾发育中发挥重要作用。 Kisspeptin-10/GPR54 信号通过 NFATc4 介导的 BMP2 表达诱导成骨细胞分化 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
---|---|---|---|---|---|
TMPY-00811 | Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein | CMV | HEK293 Cells | ||
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 92 kDa and the accession number is P13201.
|
|||||
TMPY-01201 | Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His) | CMV | HEK293 Cells | ||
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 93.2 kDa and the accession number is P13201.
|
|||||
TMPH-00007 | HMGCR Protein, Human, Recombinant (His) | Human | E. coli | ||
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
|
|||||
TMPH-00009 | OGT Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
OGT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 62.5 kDa and the accession number is O15294.
|
|||||
TMPH-00010 | MMP-14 Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis.
|
|||||
TMPJ-01470 | SCF Protein, Human, Recombinant | Human | E. coli | ||
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.
|
|||||
TMPY-00810 | Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc) | CMV | HEK293 Cells | ||
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 118 kDa and the accession number is P13201.
|
|||||
TMPY-00812 | Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc) | CMV | HEK293 Cells | ||
Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 104 kDa and the accession number is P13201.
|
|||||
TMPJ-01471 | Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant | Human/Mouse/Rat | HEK293 Cells | ||
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.
|
|||||
TMPK-01467 | HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells | ||
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.
|
|||||
TMPK-01466 | HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells | ||
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.
|
|||||
TMPH-01773 | ELANE Protein, Human, Recombinant (GST) | Human | E. coli | ||
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae. ELANE Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.6 kDa and the accession number is P08246.
|
|||||
TMPJ-01099 | IL-15RA Protein, Human, Recombinant (hFc, Human Cells) | Human | HEK293 Cells | ||
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
|
|||||
TMPY-01010 | NGF Protein, Human, Recombinant | Human | CHO Cells | ||
NGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 13.2 kDa and the accession number is P01138.
|
|||||
TMPY-04330 | Mer Protein, Human, Recombinant | Human | HEK293 Cells | ||
Mer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 54 kDa and the accession number is Q12866.
|
|||||
TMPY-02881 | RAGE Protein, Human, Recombinant | Human | HEK293 Cells | ||
RAGE Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35 kDa and the accession number is A0A1U9X785.
|
|||||
TMPY-00132 | Mesothelin Protein, Human, Recombinant | Human | HEK293 Cells | ||
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
|
|||||
TMPY-04104 | LIF Protein, Human, Recombinant | Human | HEK293 Cells | ||
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
|
|||||
TMPY-02327 | HGF Protein, Human, Recombinant | Human | CHO Cells | ||
HGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 79.7 kDa and the accession number is P14210-1.
|
|||||
TMPY-01560 | EGF Protein, Human, Recombinant | Human | E. coli | ||
EGF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.35 kDa and the accession number is P01133-1.
|
|||||
TMPY-03782 | Albumin Protein, Human, Recombinant | Human | P. pastoris (Yeast) | ||
Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
|
|||||
TMPY-00875 | Leptin Protein, Human, Recombinant | Human | E. coli | ||
Leptin Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is A4D0Y8.
|
|||||
TMPY-03484 | TCPTP Protein, Human, Recombinant | Human | Baculovirus Insect Cells | ||
TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
|
|||||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli | ||
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral mucosa, skin and in salivary glands. In aa sequence level, Human TSLP displays about 43% identity with mouse TSLP.TSLP is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells.TSLP has proliferative effects on the myeloid cell line and may initiate asthma or atopic dermatitis responses by directly activating mast cells . TSLP signals cells via the interleukin-7 receptor-α chain (IL-7Rα),shared with IL-7, together with the TSLP receptor (TSLPR) subunit. Recent studies indicate that TSLP and its receptor are novel therapeutic targets for rheumatoid arthritis,for increased intraarticular TSLP concentrations in patients has caused chemotaxis and activation of arthritogenic T cells.
|
|||||
TMPY-00395 | Insulin Protein, Human, Recombinant | Human | P. pastoris (Yeast) | ||
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
|
|||||
TMPJ-01430 | NovoNectin Protein, Human, Recombinant | Human | E. coli | ||
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a heparin binding domain II, which co-locates the cell and the virus vector on NovoNectin. This process enhances the density of both cells and vectors, and facilitates the gene transduction in the result.
|
|||||
TMPJ-00541 | CD177 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
|
|||||
TMPY-03441 | SAE1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells | ||
SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.
|
|||||
TMPY-04803 | DLL4 Protein, Human, Recombinant | Human | HEK293 Cells | ||
DLL4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55 kDa and the accession number is Q9NR61.
|
|||||
TMPY-04751 | VRK1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells | ||
VRK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 45.6 kDa and the accession number is Q99986.
|
|||||
TMPY-03274 | CXCL11 Protein, Human, Recombinant | Human | E. coli | ||
I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family.
|
|||||
TMPH-01070 | CD177 Protein, Human, Recombinant (GST & His) | Human | E. coli | ||
CD177 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 63.6 kDa and the accession number is Q8N6Q3.
|
|||||
TMPY-00749 | FGF-2 Protein, Human, Recombinant | Human | E. coli | ||
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
|
|||||
TMPY-03432 | KEAP1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells | ||
KEAP1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 69.7 kDa and the accession number is Q14145.
|
|||||
TMPY-03050 | CXCL5 Protein, Human, Recombinant | Human | E. coli | ||
CXCL5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 kDa and the accession number is P42830.
|
|||||
TMPY-02234 | CXCL9 Protein, Human, Recombinant | Human | E. coli | ||
CXCL9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.9 kDa and the accession number is Q07325.
|
|||||
TMPY-02970 | CXCL10 Protein, Human, Recombinant | Human | E. coli | ||
CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778.
|
|||||
TMPH-02283 | USP18 Protein, Human, Recombinant (His) | Human | E. coli | ||
USP18 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 47.1 kDa and the accession number is Q9UMW8.
|
|||||
TMPY-04018 | LRG1 Protein, Human, Recombinant | Human | HEK293 Cells | ||
LRG1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.1 kDa and the accession number is AAH34389.1.
|
|||||
TMPY-03890 | CD81 Protein, Human, Recombinant | Human | HEK293 Cells | ||
CD81 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 9.9 kDa and the accession number is A0A024RCB7.
|
|||||
TMPY-04683 | CD47 Protein, Human, Recombinant | Human | HEK293 Cells | ||
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
|
|||||
TMPU-00003 | STAT2 Protein, Human, Recombinant (His) | Human | E. coli | ||
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
|
|||||
TMPJ-00864 | VEGF165 Protein, Human, Recombinant | Human | HEK293 Cells | ||
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
|
|||||
TMPY-01132 | COL6A3 Protein, Human, Recombinant | Human | HEK293 Cells | ||
COL6A3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.5 kDa and the accession number is D9ZGF2.
|
|||||
TMPY-04750 | CSNK2A2 Protein, Human, Recombinant | Human | Baculovirus Insect Cells | ||
CSNK2A2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.4 kDa and the accession number is P19784.
|
|||||
TMPY-03219 | VISTA Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
VISTA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is AAH20568.1.
|
|||||
TMPY-01750 | HVEM Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
HVEM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is A0A024R052.
|
|||||
TMPY-01288 | Osteopontin Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Osteopontin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDE2.
|
|||||
TMPY-01066 | MICB Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
MICB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is A0A7D9H7X8.
|
|||||
TMPY-01369 | AGRP Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
AGRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is C6SUN5.
|