抗癌活性化合物库

Anti-Cancer Active Compound Library

产品编号： L2160

尽管在过去的几十年中癌症的研究和治疗取得了巨大的成功，但癌症仍然是人类面临的巨大挑战，给患者身心健康带来巨大的痛苦。癌细胞具有许多显著不同的生物学特征，表现出无限的增殖潜能，维持自身生长信号的持续稳定，逃避应激信号诱导的细胞凋亡，刺激血管生长，为肿瘤提供营养，同时逃避免疫系统防御和诱导局部慢性炎症，发挥其侵袭和转移能力；并且表现出异常的代谢活动，并通过突变和表观遗传机制显著改变全基因组的稳定性。

根据文献报道和有关公开资料，我们挑选了 3250 个具有已知抗癌活性的化合物组成抗癌活性库，可用于具体癌症的阳性对照及癌症机理的研究。希望我们在抗癌研究的路上，助您一臂之力！

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

3250种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
是肿瘤发生机理研究、抗肿瘤药物筛选的有效工具；
靶点含PI3K、HDAC、mTOR、CDK、Aurora Kinase、JAK等；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS检测技术保证产品高纯度和高质量，减少假阳性发生概率。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

Apoptosis (671)

Autophagy (367)

Endogenous Metabolite (119)

DNA/RNA Synthesis (118)

Antibacterial (113)

CDK (105)

EGFR (101)

PI3K (99)

VEGFR (98)

Microtubule Associated (74)

NF-κB (67)

PDGFR (65)

Topoisomerase (62)

Antibiotic (62)

FLT (61)

mTOR (59)

Epigenetic Reader Domain (58)

Antifungal (55)

FGFR (55)

c-Kit (55)

HDAC (51)

c-Met/HGFR (50)

Akt (49)

Parasite (48)

Reactive Oxygen Species (48)

COX (48)

Dehydrogenase (47)

HIV Protease (45)

Raf (44)

Src (43)

JAK (43)

Histone Methyltransferase (42)

BCL (42)

HSP (41)

STAT (41)

Ferroptosis (39)

Estrogen Receptor/ERR (39)

PARP (39)

Nucleoside Antimetabolite/Analog (39)

Wnt/beta-catenin (36)

ERK (36)

Estrogen/progestogen Receptor (35)

Bcr-Abl (35)

Aurora Kinase (35)

Influenza Virus (35)

p38 MAPK (33)

PKC (32)

TNF (31)

P450 (29)

Androgen Receptor (28)

Antioxidant (27)

Mitophagy (27)

MEK (27)

Ras (27)

HER (27)

DNA Alkylator/Crosslinker (26)

Phosphatase (26)

Caspase (26)

IL Receptor (26)

Calcium Channel (25)

E1/E2/E3 Enzyme (25)

MMP (25)

ALK (25)

PPAR (24)

AMPK (24)

p53 (24)

BTK (22)

c-RET (22)

DNA-PK (21)

HSV (21)

Chk (21)

Sirtuin (21)

TAM Receptor (21)

FAK (21)

Proteasome (20)

GSK-3 (20)

Virus Protease (20)

ROS (20)

IGF-1R (20)

Retinoid Receptor (20)

Lipoxygenase (19)

P-gp (19)

Trk receptor (19)

Potassium Channel (19)

AChR (19)

PDE (18)

DUB (18)

Gamma-secretase (17)

TGF-beta/Smad (17)

MAPK (17)

Mdm2 (16)

Tyrosine Kinases (16)

Pim (16)

CXCR (16)

Antiviral (16)

TLR (16)

SARS-CoV (16)

c-Fms (16)

PLK (16)

HIF/HIF Prolyl-Hydroxylase (16)

DNA Alkylation (15)

Nrf2 (15)

ATM/ATR (15)

S6 Kinase (15)

HBV (14)

Mitochondrial Metabolism (14)

HIF (14)

Sodium Channel (14)

DNA Methyltransferase (14)

JNK (13)

Hedgehog/Smoothened (13)

PDK (13)

5-HT Receptor (13)

Carbonic Anhydrase (12)

Histamine Receptor (12)

PKA (12)

Fatty Acid Synthase (12)

Casein Kinase (12)

GABA Receptor (12)

Kinesin (12)

HCV Protease (11)

Integrin (11)

Antifolate (11)

Adrenergic Receptor (11)

IAP (11)

CSF-1R (11)

Smo (11)

Indoleamine 2,3-Dioxygenase (IDO) (11)

Histone Acetyltransferase (11)

Aromatase (11)

ROS Kinase (11)

Transferase (10)

Dopamine Receptor (10)

Histone Demethylase (10)

Rho (10)

Serine/threonin kinase (10)

TRP/TRPV Channel (10)

Syk (10)

Tyrosinase (10)

Adenosine Receptor (9)

MAO (9)

Interleukin (9)

Prostaglandin Receptor (9)

IκB/IKK (9)

Ligand for E3 Ligase (9)

ATPase (8)

YAP (8)

c-Myc (8)

Serine Protease (8)

Drug Metabolite (8)

CaMK (8)

AChE (8)

Beta Amyloid (8)

Phospholipase (8)

Anti-infection (8)

NO Synthase (8)

S1P Receptor (8)

NOS (7)

Reductase (7)

ROCK (7)

Glucocorticoid Receptor (7)

Antifection (7)

Isocitrate Dehydrogenase (IDH) (7)

Telomerase (7)

transporter (7)

Reverse Transcriptase (7)

DHFR (6)

PERK (6)

Progesterone Receptor (6)

GNRH Receptor (6)

Glucokinase (6)

Aryl Hydrocarbon Receptor (6)

iGluR (6)

PAK (6)

DNA (6)

Wee1 (6)

Ephrin Receptor (6)

GPR (6)

cholecystokinin (6)

PD-1/PD-L1 (6)

PROTACs (5)

Monocarboxylate transporter (5)

LPL Receptor (5)

DYRK (5)

NADPH (5)

Tie-2 (5)

Glutathione Peroxidase (5)

Cysteine Protease (5)

RIP kinase (5)

P2X Receptor (5)

Opioid Receptor (5)

CCR (5)

Lipid (5)

BCRP (5)

IRAK (5)

Chloride channel (4)

Proton pump (4)

ROR (4)

Ligands for Target Protein for PROTAC (4)

IFNAR (4)

GTPase (4)

cell cycle arrest (4)

Liver X Receptor (4)

NAMPT (4)

IDO (4)

IRE1 (4)

UGT (4)

MTH1 (4)

NMDAR (4)

Molecular Glues (4)

KSP (4)

GluR (4)

OXPHOS (4)

STING (4)

Aminopeptidase (4)

MELK (4)

Cannabinoid Receptor (4)

Discoidin Domain Receptor (DDR) (4)

BMI-1 (4)

NOD (4)

Thrombin (4)

AhR (4)

Monoamine Oxidase (4)

ABC (3)

MRP (3)

PYK2 (3)

Glutaminase (3)

Myosin (3)

Hexokinase (3)

FAAH (3)

Endothelin Receptor (3)

PAD (3)

cAMP (3)

Survivin (3)

Acyltransferase (3)

CD73 (3)

PAI-1 (3)

Methionine Adenosyltransferase (MAT) (3)

GPX (3)

LPA Receptor (3)

CRISPR/Cas9 (3)

Hydroxylase (3)

Adenosine deaminase (3)

Complement System (3)

Platelet aggregation (3)

HMG-CoA Reductase (3)

PKM (3)

MALT (2)

NEDD8 (2)

CRM1 (2)

Amino Acids and Derivatives (2)

LTR (2)

RAR/RXR (2)

Lipase (2)

RAAS (2)

TOPK (2)

Factor Xa (2)

Galectin (2)

Serotonin Transporter (2)

Leukotriene Receptor (2)

Immunology/Inflammation related (2)

Annexin A (2)

Adiponectin receptor (2)

APC (2)

Bombesin Receptor (2)

PTEN (2)

Somatostatin (2)

ACK (2)

ATP Citrate Lyase (2)

MNK (2)

Porcupine (2)

GPCR19 (2)

Decarboxylase (2)

ASK (2)

RSV (2)

GST (2)

ribosome (2)

KLF (2)

PI4K (2)

Neurokinin receptor (2)

Protease-activated Receptor (2)

lysosomal autophagy (2)

p97 (2)

NOD-like Receptor (NLR) (2)

advanced glycation end products (1)

Adenylyl cyclase (1)

NPC1L1 (1)

CD38 (1)

CYP19A1 (1)

NUDIX hydrolase (1)

MyD88 (1)

Arginase (1)

Na+/Ca2+ Exchanger (1)

CETP (1)

LHRH (1)

VDA (1)

Melatonin Receptor (1)

OCT (1)

CaSR (1)

VDAC (1)

Hck (1)

Neurotensin Receptor (1)

FXR (1)

Stemness kinase (1)

RANKL/RANK (1)

Amylase (1)

SIK (1)

FLAP (1)

PAFR (1)

Haspin Kinase (1)

DNA gyrase (1)

Glucosidase (1)

DPP-4 (1)

Thioredoxin (1)

Xanthine Oxidase (1)

SGLT (1)

PGE Synthase (1)

Glutathione reductase (1)

LRRK2 (1)

Free radical scavengers (1)

GluCls (1)

Pyroptosis (1)

Hippo pathway (1)

Carboxypeptidase (1)

GHSR (1)

SGK (1)

DAPK (1)

Sigma receptor (1)

MLK (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

注册成功