抗体抑制剂

单克隆抗体是由单个B 淋巴细胞克隆所分泌的抗体,由于B 淋巴细胞只能产生一种专有的、针对一种抗原决定簇的抗体,所以具有理化性质高度专一、生物活性单一、与抗原结合特异性强等特点。因此,它也被形象地被称为“生物导弹”, 现有的抗体药物大多属于此类抗体。近年来,单克隆抗体药物迅速发展,并逐渐成为生物医药领域发展的主要方向。

陶素可为您提供30多种抗体抑制剂,包括多种免疫检查点抑制剂和其他类型的靶向抗体抑制剂,满足您的实验需求。陶素始终致力于服务“科研人员”,将最前沿的研究报道,最热门的研究产品推送给各位科研人员。

产品编号 产品名称
T9901 Adalimumab Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
T9902 Atezolizumab Atezolizumab (anti-PD-L1) is a fully humanized, IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1, but not the interaction of...
T9903 Avelumab Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.
T9904 Bevacizumab Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.
T9906 Ipilimumab Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibit...
T9907 Nivolumab Nivolumab (anti-PD-1) is a genetically engineered, fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human ce...
T9908 Pembrolizumab Pembrolizumab is a humanized antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.
T9909 Pertuzumab Pertuzumab (anti-HER2), a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2...
T9910 Rituximab Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM.
T9911 Tocilizumab Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
T9912 Trastuzumab Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER...
T9913 Ustekinumab Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
T9914 Vedolizumab Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
T9915 Eculizumab Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
T9916 Alirocumab Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
T9917 Denosumab Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
T9918 Daratumumab Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells.
T9919 Alemtuzumab Alemtuzumab is a humanized monoclonal antibody against CD52, an antigen found on the surface of normal and malignant lymphocytes.
T9920 Evolocumab Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9).
T9921 Infliximab Infliximab is a humanized antibody against tumor necrosis factor α (TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
T9922 Matuzumab Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR, frequently associated with the growth of blood vessels in...
T9923 Nimotuzumab Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor (EGFR).
T9924 Obinutuzumab/afutuzumab Obinutuzumab (GA101) a novel glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.
T9925 Ofatumumab Ofatumumab is a fully human monoclonal antibody to CD20, which appears to inhibit early-stage B lymphocyte activation
T9926 Omalizumab Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE)
T9927 Panitumumab Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor (EGFR).
T9928 Ranibizumab Ranibizumab is an antibody fragment without the Fc portion and affinity-matured to more strongly bind VEGF-A
T9929 Ramucirumab Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T9930 Secukinumab Secukinumab is a fully humanized, monoclonal anti-IL-17A antibody, and the first in its class to be approved by the US Food and Drug Administration for the treat...
Adalimumab
T9901CAS 331731-18-1
Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
Atezolizumab
T9902CAS 1380723-44-3
Atezolizumab (anti-PD-L1) is a fully humanized, IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1, but not the interaction of...
Avelumab
T9903CAS 1537032-82-8
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity.
Bevacizumab
T9904CAS 216974-75-3
Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.
Ipilimumab
T9906CAS 477202-00-9
Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibit...
Nivolumab
T9907CAS 946414-94-4
Nivolumab (anti-PD-1) is a genetically engineered, fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human ce...
Pembrolizumab
T9908CAS 1374853-91-4
Pembrolizumab is a humanized antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy.
Pertuzumab
T9909CAS 380610-27-5
Pertuzumab (anti-HER2), a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2...
Rituximab
T9910CAS 174722-31-7
Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM.
Tocilizumab
T9911CAS 375823-41-9
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
Trastuzumab
T9912CAS 180288-69-1
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER...
Ustekinumab
T9913CAS 815610-63-0
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
Vedolizumab
T9914CAS 943609-66-3
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
Eculizumab
T9915CAS 219685-50-4
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
Alirocumab
T9916CAS 1245916-14-6
Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
Denosumab
T9917CAS 615258-40-7
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
Daratumumab
T9918CAS 945721-28-8
Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells.
Alemtuzumab
T9919CAS 216503-57-0
Alemtuzumab is a humanized monoclonal antibody against CD52, an antigen found on the surface of normal and malignant lymphocytes.
Evolocumab
T9920CAS 1256937-27-5
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9).
Infliximab
T9921CAS 170277-31-3
Infliximab is a humanized antibody against tumor necrosis factor α (TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
Matuzumab
T9922CAS 339186-68-4
Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR, frequently associated with the growth of blood vessels in...
Nimotuzumab
T9923CAS 828933-51-3
Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor (EGFR).
Obinutuzumab/afutuzumab
T9924CAS 949142-50-1
Obinutuzumab (GA101) a novel glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.
Ofatumumab
T9925CAS 679818-59-8
Ofatumumab is a fully human monoclonal antibody to CD20, which appears to inhibit early-stage B lymphocyte activation
Omalizumab
T9926CAS 242138-07-4
Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE)
Panitumumab
T9927CAS 339177-26-3
Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor (EGFR).
Ranibizumab
T9928CAS 347396-82-1
Ranibizumab is an antibody fragment without the Fc portion and affinity-matured to more strongly bind VEGF-A
Ramucirumab
T9929CAS 947687-13-0
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
Secukinumab
T9930CAS 875356-43-7
Secukinumab is a fully humanized, monoclonal anti-IL-17A antibody, and the first in its class to be approved by the US Food and Drug Administration for the treat...
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