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代谢性疾病

代谢性疾病是指体内代谢过程发生障碍,导致某些代谢物质如氨基酸、有机酸、脂肪酸、糖和激素等堆积或缺乏而引起的疾病。

代谢性疾病广义上是指机体中间代谢某个环节障碍所引起的疾病,可分为遗传性代谢疾病和获得性代谢疾病。遗传性代谢疾病为先天性代谢缺陷,包括果糖不耐受症、糖原贮积症、半乳糖血症、白化病等。获得性代谢疾病可由环境因素引起,或遗传因素和环境因素相互作用所致,包括糖尿病、血脂异常、痛风、低血糖症、低白蛋白血症等。

Kynurenine Pathway Library From Enamine EN3200 犬尿氨酸通路化合物库 13120 compounds Human Endogenous Metabolite Compound Library Plus L2501 人内源代谢化合物库 Plus 1000 compounds Mouse Metabolite Compound Library L2530 小鼠代谢化合物库 218 compounds Glucagon receptor antagonist library OT5200 胰高血糖素受体拮抗剂库 526 compounds Glycerol-3-phosphate Phosphatase PGP Targeted Library LF1036 甘油-3-磷酸磷酸酶PGP靶向库 2008 compounds Glutamine Metabolism Compound Library L2550 谷氨酰胺代谢化合物库 565 compounds Glycometabolism Compound Library L2520 糖代谢化合物库 702 compounds Human Endogenous Metabolite Library L2500 人内源代谢化合物库 499 compounds Steroid Mimetics Library AN5400 类固醇模拟物化合物库 1456 compounds Sodium glucose cotransporter 2 (SGLT2) targeted library OA4400 SGLT2靶向化合物库 674 compounds Steroid-like Library US4000 类脂化合物库 20542 compounds Human Metabolite Library L2570 人代谢物化合物库 5100 compounds Nuclear Receptor Compound Library L1510 核受体化合物库 631 compounds Metabolism Compound Library L2560 代谢化合物库 2320 compounds Endocrinology-Hormone Compound Library L2400 内分泌激素分子库 924 compounds Anti-Metabolism Disease Compound Library L5200 抗代谢疾病化合物库 1544 compounds Histone Modification Compound Library L3500 组蛋白修饰化合物库 469 compounds Glycolysis Compound Library L2521 糖酵解化合物库 555 compounds 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Targeted Library LF4000 PDK1靶向化合物库 760 compounds Lipid Metabolism Compound Library L2510 脂代谢化合物库 492 compounds Adenosine receptor antagonist library OT8800 腺苷受体拮抗剂库 110 compounds Lipid Metabolism Library DD5300 脂质代谢化合物库 9149 compounds 3-phosphoinositide-dependent kinase-1 (PDK-1) inhibitor library OA4500 PDK-1抑制剂库 496 compounds Anti-Obesity Compound Library L7100 抗肥胖化合物库 2450 compounds Adenosine Receptors Targeted Library DP2400 腺苷受体靶向化合物库 21000 compounds Antiobesity library OT3100 抗肥胖化合物库OT 1714 compounds Dipeptidyl peptidase-4 (DPP4) targeted library OA4000 DPP4 靶向化合物库 653 compounds Gut Microbial Metabolite Library L2540 肠道微生物代谢化合物库 540 compounds Anti-Diabetic Compound Library L1900 抗糖尿病库 800 compounds Steroid-like-compounds DP2380 类固醇化合物库 506 compounds HMG-CoA reductase inhibitor library OA9600 HMG-CoA 还原酶抑制剂库 806 compounds Bioactive Lipid Compound Library L7000 活性脂质化合物库 385 compounds 11β-HSD1 targeted library OA3800 11β-HSD1 靶向化合物库 924 compounds
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