组蛋白修饰化合物库

Histone Modification Compound Library

产品编号： L3500

组蛋白修饰（histone modification）是指组蛋白在相关酶作用下发生甲基化、乙酰化、磷酸化、腺苷酸化、泛素化、ADP 核糖基化等化学修饰的过程。组蛋白修饰可通过改变染色质结构或募集组蛋白修饰物来影响基因表达，因此组蛋白修饰在多种生物过程中起作用，例如转录激活与失活、染色体包装、DNA 损伤与修复等。定量检测各种组蛋白修饰将为更好地理解细胞代谢过程的表观遗传调节提供有用的信息，促进组蛋白修饰酶靶向药物的发展。

TargetMol 组蛋白修饰化合物库是由480 个组蛋白修饰研究相关的小分子的独特集合，用于组蛋白修饰相关的研究以及药物的筛选，可用于高通量、高内涵筛选。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

480个组蛋白修饰相关的小分子化合物的特有集合，用于高通量、高内涵筛选；
产品经过临床验证和临床实验，具有生物安全保障和一定的生物活性；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR和HPLC检测技术保证产品高纯度和高质量；
所有化合物现货供应。

化合物库定制

我们的化合物库可以灵活定制！了解更多

化合物库咨询

化合物库组成

Epigenetic Reader Domain (150)

Histone Methyltransferase (118)

HDAC (113)

Apoptosis (67)

Sirtuin (58)

Histone Demethylase (39)

Histone Acetyltransferase (31)

Autophagy (29)

HIV Protease (10)

Mitophagy (5)

Endogenous Metabolite (5)

PI3K (4)

Histamine Receptor (4)

COX (4)

DNA/RNA Synthesis (4)

PROTACs (3)

Dehydrogenase (3)

Adenosine Receptor (3)

Parasite (3)

MAO (3)

PDE (3)

CDK (3)

JAK (3)

EGFR (3)

Influenza Virus (3)

NF-κB (3)

Sodium Channel (3)

DNA Methyltransferase (3)

p53 (3)

Monoamine Oxidase (3)

Dopamine Receptor (2)

Ligands for Target Protein for PROTAC (2)

RAAS (2)

Phosphatase (2)

Virus Protease (2)

PPAR (2)

Wnt/beta-catenin (2)

ERK (2)

Gamma-secretase (2)

HSV (2)

PAD (2)

Nrf2 (2)

AMPK (2)

5-HT Receptor (2)

GABA Receptor (2)

P450 (2)

PLK (2)

TNF (2)

AChR (2)

FLT (2)

Mdm2 (1)

DNA-PK (1)

Src (1)

Ferroptosis (1)

PKA (1)

HBV (1)

Tyrosine Kinases (1)

Antifolate (1)

Caspase (1)

PKC (1)

Adrenergic Receptor (1)

Topoisomerase (1)

UGT (1)

Bcr-Abl (1)

NMDAR (1)

Mitochondrial Metabolism (1)

BCL (1)

Reactive Oxygen Species (1)

Fatty Acid Synthase (1)

PDGFR (1)

MMP (1)

Androgen Receptor (1)

mTOR (1)

Antibacterial (1)

Telomerase (1)

Akt (1)

Antiviral (1)

SARS-CoV (1)

transporter (1)

RSV (1)

Carboxypeptidase (1)

Reverse Transcriptase (1)

STAT (1)

Ligand for E3 Ligase (1)

Phospholipase (1)

MEK (1)

BMI-1 (1)

Tyrosinase (1)

HER (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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