代谢化合物库 | 陶术生物

代谢化合物库

Metabolism Compound Library

产品编号： L2560

代谢是生物体内发生的用于维持生命的一系列有序化学反应的总称。这些反应使得生物体能够生长、繁殖以及对外界环境做出反应。代谢通常分为两类：分解代谢和合成代谢；分解代谢又称为异化作用，可以将环境中或细胞存储的营养物质进行分解以获得能量；合成代谢又称为同化作用，可以利用能量来合成细胞中的各个组分，二者的平衡使生物体保持自身的稳定，以适应环境。代谢中的化学反应几乎都是在酶的催化下进行的，从一个代谢物到另一个代谢物的代谢过程是通过一系列连续的酶促反应实现的，这种连续的酶促反应称为代谢途径。代谢紊乱、机体代谢途径的失调或中断会引发一系列代谢相关疾病。如糖尿病、肥胖、高血压、心血管疾病、癌症等。

Targetmol 代谢化合物库收集了2350 种代谢途径相关的化合物，是研究代谢相关疾病有用的工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

特点

2350种代谢途径相关生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
靶向糖代谢、脂质代谢、核苷酸代谢等多个代谢途径；靶点包括GLUT、Hexokinase、Pyruvate Kinase；ATGL、MAGL、FAAH等代谢相关热门靶点；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、活性描述等；

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化合物库组成

Autophagy (305)

Apoptosis (290)

PI3K (192)

Endogenous Metabolite (164)

Reactive Oxygen Species (163)

Calcium Channel (159)

P450 (143)

Dehydrogenase (122)

PDE (114)

PPAR (111)

mTOR (101)

Akt (97)

Antibacterial (93)

AMPK (82)

Phosphatase (78)

GSK-3 (71)

COX (60)

Mitochondrial Metabolism (53)

NF-κB (51)

HSP (50)

Lipoxygenase (49)

Phospholipase (48)

Antibiotic (46)

Ferroptosis (46)

Parasite (45)

CDK (42)

HIF/HIF Prolyl-Hydroxylase (40)

DNA-PK (37)

Antifungal (35)

Carbonic Anhydrase (34)

Casein Kinase (34)

Transferase (34)

p53 (33)

Serine/threonin kinase (33)

DNA/RNA Synthesis (32)

IGF-1R (31)

HIF (30)

Potassium Channel (30)

S6 Kinase (30)

AChR (26)

ERK (26)

HIV Protease (26)

Reductase (26)

Retinoid Receptor (26)

Fatty Acid Synthase (24)

Glucosidase (24)

Influenza Virus (24)

DPP-4 (23)

NADPH (23)

ATM/ATR (22)

FAAH (22)

Indoleamine 2,3-Dioxygenase (IDO) (22)

PKC (22)

Proteasome (22)

ROS (22)

transporter (22)

Amino Acids and Derivatives (21)

FXR (21)

HMG-CoA Reductase (21)

PKA (21)

Antioxidant (20)

Acyltransferase (19)

Glucokinase (19)

PDK (19)

ROR (19)

Sodium Channel (19)

Wnt/beta-catenin (19)

Lipase (18)

Mitophagy (18)

Caspase (17)

Glutathione Peroxidase (17)

Hydroxylase (17)

Src (17)

TNF (17)

Epoxide Hydrolase (16)

GABA Receptor (16)

Glucocorticoid Receptor (16)

p38 MAPK (16)

VEGFR (16)

PARP (15)

SGLT (15)

Liver X Receptor (14)

Virus Protease (14)

DHFR (13)

Factor Xa (13)

IL Receptor (13)

JNK (13)

STAT (13)

Adenosine Receptor (12)

Adrenergic Receptor (12)

P-gp (12)

PI4K (12)

Xanthine Oxidase (12)

5-HT Receptor (11)

Acetyl-CoA Carboxylase (11)

Aminopeptidase (11)

Antifolate (11)

FLT (11)

IDO (11)

Isocitrate Dehydrogenase (IDH) (11)

Lipid (11)

MMP (11)

Stearoyl-CoA Desaturase (SCD) (11)

TRP/TRPV Channel (11)

Aurora Kinase (10)

Histamine Receptor (10)

HSV (10)

PAI-1 (10)

Prostaglandin Receptor (10)

Anti-infection (9)

ATP Citrate Lyase (9)

BCL (9)

EGFR (9)

Estrogen/progestogen Receptor (9)

HBV (9)

Interleukin (9)

MEK (9)

NO Synthase (9)

SARS-CoV (9)

SGK (9)

Sirtuin (9)

UGT (9)

ATPase (8)

CaMK (8)

c-Met/HGFR (8)

GPR (8)

HCV Protease (8)

HDAC (8)

NAMPT (8)

Nrf2 (8)

PKM (8)

ROCK (8)

Serine Protease (8)

Topoisomerase (8)

Tyrosinase (8)

ALK (7)

Chk (7)

IκB/IKK (7)

MAPK (7)

Neprilysin (7)

Phosphorylase (7)

PTEN (7)

TGF-beta/Smad (7)

AChE (6)

Androgen Receptor (6)

Aryl Hydrocarbon Receptor (6)

Bcr-Abl (6)

CETP (6)

Dopamine Receptor (6)

E1/E2/E3 Enzyme (6)

Estrogen Receptor/ERR (6)

FAK (6)

FGFR (6)

LDL (6)

Mdm2 (6)

PDGFR (6)

Adenosine deaminase (5)

Antiviral (5)

Chloride channel (5)

Decarboxylase (5)

MAO (5)

MELK (5)

Microtubule Associated (5)

NADPH-oxidase (5)

PERK (5)

Proton pump (5)

RAAS (5)

SIK (5)

Thrombin (5)

Angiotensin-converting Enzyme (ACE) (4)

Beta Amyloid (4)

Cannabinoid Receptor (4)

Carboxypeptidase (4)

CAT (4)

Drug Metabolite (4)

GluR (4)

GST (4)

iGluR (4)

Integrin (4)

Leukotriene Receptor (4)

LTR (4)

MAGL (4)

NPC1L1 (4)

Raf (4)

Ras (4)

RSV (4)

Syk (4)

Trk receptor (4)

Tyrosine Kinases (4)

AhR (3)

BACE (3)

c-RET (3)

DYRK (3)

Glutathione reductase (3)

GPCR19 (3)

GPX (3)

HER (3)

Hexokinase (3)

IAP (3)

JAK (3)

Myosin (3)

NEDD8 (3)

NMDAR (3)

Opioid Receptor (3)

OXPHOS (3)

PLK (3)

RAR/RXR (3)

Reverse Transcriptase (3)

TAM Receptor (3)

TLR (3)

ABC (2)

Antifection (2)

Arginase (2)

BCRP (2)

Beta-Secretase (2)

cell cycle arrest (2)

c-Fms (2)

CFTR (2)

cholecystokinin (2)

c-Kit (2)

Complement System (2)

Cysteine Protease (2)

DNA Alkylator/Crosslinker (2)

Epigenetic Reader Domain (2)

FLAP (2)

Free radical scavengers (2)

Gamma-secretase (2)

Glutaminase (2)

hCE (2)

Hedgehog/Smoothened (2)

IFNAR (2)

MLK (2)

Monocarboxylate transporter (2)

MRP (2)

Na+/Ca2+ Exchanger (2)

NOD (2)

NOS (2)

Nucleoside Antimetabolite/Analog (2)

P2Y Receptor (2)

PAK (2)

PGC-1α (2)

Pim (2)

Rho (2)

ribosome (2)

RIP kinase (2)

S1P Receptor (2)

Taste receptor (2)

YAP (2)

aconitase (1)

Adenylyl cyclase (1)

Amylase (1)

Anion Exchanger (1)

APC (1)

Aromatase (1)

Bombesin Receptor (1)

cAMP (1)

CRISPR/Cas9 (1)

CSF-1R (1)

DAPK (1)

DNA (1)

DNA Alkylation (1)

DNA Methyltransferase (1)

DprE1 (1)

DUB (1)

Dynamin (1)

FABP (1)

Gap Junction Protein (1)

GluCls (1)

GSNOR (1)

GTPase (1)

Guanylate cyclase (1)

Histone Demethylase (1)

Histone Methyltransferase (1)

Hydrogenase (1)

Immunology/Inflammation related (1)

Kinesin (1)

LPA Receptor (1)

LRRK2 (1)

Melatonin Receptor (1)

Monoamine Oxidase (1)

Monoamine Transporter (1)

MyD88 (1)

N-Acetylglucosaminyltransferase (1)

NOD-like Receptor (NLR) (1)

Norepinephrine (1)

NUDIX hydrolase (1)

OAT (1)

P2X Receptor (1)

PAD (1)

PAFR (1)

PD-1/PD-L1 (1)

PGE Synthase (1)

Platelet aggregation (1)

Porcupine (1)

Progesterone Receptor (1)

PYK2 (1)

Pyroptosis (1)

ROS Kinase (1)

Somatostatin (1)

stilbene oxidase (1)

STING (1)

Survivin (1)

Telomerase (1)

Thioredoxin (1)

Tie-2 (1)

Transaminase (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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