转录因子库 | 陶术生物

转录因子库

Transcription Factor-Targeted Compound Library

产品编号： L1380

转录因子能够与基因上特定的核苷酸序列结合，从而调控基因的转录。基因转录的活化和抑制在细胞生理活动中起着重要作用，影响细胞发育和细胞间信号传导、调节细胞周期。

TargetMol 收集 704 种转录因子靶向的活性小分子组成转录因子库，是研究转录因子在疾病调控中的作用机制的有用工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

704种细胞转录因子相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
部分产品经过临床验证和临床实验，具有生物安全保障和一定的生物活性；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、活性描述等；
NMR和HPLC检测技术保证产品高纯度和高质量；
所有化合物现货供应。

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化合物库组成

NF-κB (224)

Apoptosis (113)

PPAR (109)

STAT (88)

Autophagy (85)

Androgen Receptor (60)

Endogenous Metabolite (45)

Nrf2 (43)

HIF/HIF Prolyl-Hydroxylase (38)

p53 (36)

COX (35)

Antibacterial (32)

HIF (28)

TNF (26)

ERK (25)

Aryl Hydrocarbon Receptor (23)

Ferroptosis (21)

E1/E2/E3 Enzyme (20)

p38 MAPK (20)

Mdm2 (19)

Reactive Oxygen Species (19)

IL Receptor (16)

Akt (15)

c-Myc (15)

DNA/RNA Synthesis (15)

JAK (15)

JNK (15)

c-Fms (13)

AhR (12)

CSF-1R (12)

HIV Protease (12)

BCL (11)

P450 (11)

Antibiotic (10)

Antifungal (10)

Caspase (10)

Influenza Virus (10)

Parasite (10)

AMPK (9)

MMP (9)

IκB/IKK (8)

NO Synthase (8)

ROR (8)

Sirtuin (8)

Antioxidant (7)

c-Kit (7)

Dehydrogenase (7)

Lipoxygenase (7)

VEGFR (7)

Beta Amyloid (6)

HSP (6)

Interleukin (6)

Mitophagy (6)

NOS (6)

PARP (6)

Potassium Channel (6)

CDK (5)

FLT (5)

MEK (5)

PI3K (5)

Prostaglandin Receptor (5)

Proteasome (5)

Sodium Channel (5)

TLR (5)

Tyrosinase (5)

Virus Protease (5)

Anti-infection (4)

Drug Metabolite (4)

EGFR (4)

Epigenetic Reader Domain (4)

Estrogen/progestogen Receptor (4)

GABA Receptor (4)

HDAC (4)

IAP (4)

PDE (4)

Retinoid Receptor (4)

Topoisomerase (4)

TRP/TRPV Channel (4)

Wnt/beta-catenin (4)

AChE (3)

Antifection (3)

Calcium Channel (3)

Cannabinoid Receptor (3)

FAK (3)

Glucocorticoid Receptor (3)

GPR (3)

HCV Protease (3)

IGF-1R (3)

Leukotriene Receptor (3)

Ligand for E3 Ligase (3)

mTOR (3)

NOD-like Receptor (NLR) (3)

PDGFR (3)

PGE Synthase (3)

Progesterone Receptor (3)

RAR/RXR (3)

ROS (3)

Src (3)

transporter (3)

AChR (2)

Adrenergic Receptor (2)

ATPase (2)

CaMK (2)

Chloride channel (2)

Decarboxylase (2)

DNA Alkylator/Crosslinker (2)

Estrogen Receptor/ERR (2)

Glucosidase (2)

Glutathione Peroxidase (2)

GSK-3 (2)

HER (2)

Histone Acetyltransferase (2)

HSV (2)

IFNAR (2)

Integrin (2)

Mitochondrial Metabolism (2)

Molecular Glues (2)

NOD (2)

OCT (2)

Opioid Receptor (2)

P-gp (2)

Phosphatase (2)

PKC (2)

Raf (2)

Ras (2)

S6 Kinase (2)

TGF-beta/Smad (2)

ABC (1)

Adenosine deaminase (1)

Aminopeptidase (1)

Antiviral (1)

Aromatase (1)

ATP Citrate Lyase (1)

BACE (1)

Bcr-Abl (1)

cAMP (1)

CCR (1)

CFTR (1)

CXCR (1)

Cysteine Protease (1)

DNA Methyltransferase (1)

Dopamine Receptor (1)

DUB (1)

Epoxide Hydrolase (1)

FGFR (1)

FLAP (1)

FOXO1 (1)

Free radical scavengers (1)

Glucokinase (1)

GST (1)

Guanylate cyclase (1)

HBV (1)

hCE (1)

Histamine Receptor (1)

Immunology/Inflammation related (1)

IRAK (1)

KLF (1)

LDL (1)

Ligands for Target Protein for PROTAC (1)

Liver X Receptor (1)

LTR (1)

MAO (1)

MAPK (1)

Microtubule Associated (1)

NADPH (1)

NADPH-oxidase (1)

NAMPT (1)

NMDAR (1)

Norepinephrine (1)

NPC1L1 (1)

Nucleoside Antimetabolite/Analog (1)

PAK (1)

PD-1/PD-L1 (1)

PDK (1)

PKA (1)

PKM (1)

PLK (1)

PROTACs (1)

Proton pump (1)

PTEN (1)

Reductase (1)

Reverse Transcriptase (1)

Rho (1)

S1P Receptor (1)

SARS-CoV (1)

STING (1)

Thrombin (1)

UGT (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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