| T6428 |
BV6 |
BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.
|
| T7613 |
β-Casomorphin, human(TFA) |
β-Casomorphin, human(TFA) is an opioid receptor agonist.
|
| T2692 |
Dalbavancin Impurity |
Dalbavancin Impurity is effective against Gram positive bacteria.
|
| T1665 |
Daptomycin |
Daptomycin is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
|
| T6564 |
Leupeptin Hemisulfate |
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
|
| T7624 |
DAPTA(TFA) |
DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities.
|
| T6763 |
AT406 |
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIA...
|
| T3984 |
GLP-1(7-36) |
GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays vari...
|
| T8221 |
INSULIN |
INSULIN is a polypeptide hormone that regulates the level of glucose.
|
| T7828 |
Bhsar-sp |
Bhsar-sp is an agonist of NK1 receptor.
|
| T7566 |
GRGDSPK |
GRGDSPK is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.
|
| T1608 |
Exherin trifluoroacetate |
Exherin (ADH-1) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitivel...
|
| T7570 |
RGD peptide GRGDNP(2TFA) |
RGD peptide GRGDNP(2TFA) is a integrin-ligand interactions inhibitor.
|
| T3226 |
Paritaprevir |
Paritaprevir is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3...
|
| T8231 |
Adrenocorticotropic Hormone (ACTH) (1-39), human |
Adrenocorticotropic Hormone (ACTH) (1-39), human is an agonist of melanocortin receptor.
|
| T1245 |
Colistin sulfate (1066-17-7 free base) |
Colistin is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
|
| T3247 |
Lysozyme |
Lysozyme is a bactericidal enzyme present in the chicken eggwhite, and it lyses gram-positive bacteria.
|
| T6006 |
Romidepsin |
Romidepsin is an intravenously administered histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous a...
|
| T1381 |
Milbemycin oxime |
Milbemycin oxime is a broad spectrum antiparasitic, used as a veterinary drug.
|
| T2154 |
MG132 |
MG-132 is a potent cell-permeable 20S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).
|
| T6830 |
Epoxomicin |
Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH ca...
|
| T6881 |
LTX315 |
LTX-315, the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.
|
| T4547 |
Grazoprevir |
MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.0...
|
| T8318 |
BNC210 |
BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
|
| T7577 |
Angiotensin III, human, mouse(3TFA) |
Angiotensin III, human, mouse(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
|
| T6792 |
BQ123 |
BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
|
| T5126 |
Glecaprevir |
Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).
|
| T7619 |
OVA Peptide 257-264 (2TFA) |
OVA Peptide 257-264 (2TFA) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.
|
| T1679 |
Thiostrepton |
Thiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastiti...
|
| T4286 |
Fmoc-Val-Ala-PAB |
Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD...
|
| T0832 |
Vancomycin hydrochloride |
Vancomycin Hydrochloride is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and...
|
| T1100 |
Polymyxin B sulfate (1404-26-8 free base) |
Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and ha...
|
| T1441 |
Capastat sulfate |
Capreomycin Sulfate, a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis.
|
| T1226 |
Bacitracin |
Bacitracin, a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.
|
| T2208 |
Zinc bacitracin |
Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from M...
|
| T1130 |
Gramicidin |
A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is ...
|
| T3967 |
Exendin-4 |
Exendin-4 is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer ...
|
| T3633 |
Crenigacestat |
LY3039478 is an orally bioavailable Notch inhibitor with an IC50 of ~1nM in most of the tumor cell lines tested. LY3039478 effectively inhibits mutant Notch rece...
|
| T5334 |
VL285 |
VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
|
| T3617 |
Ivosidenib |
Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a...
|
| T4S1796 |
Heterophyllin B |
Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regula...
|
| T4102 |
Goserelin acetate |
Goserelin acetate is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
|
| T7562 |
β-Amyloid 31-35(TFA) |
β-Amyloid 31-35(TFA) is the shortest sequence of native Amyloid-β peptide.
|
| T7489 |
MART-1 (26-35) human |
MART-1 (26-35) human is amino acid residue 26 to 35 of MART-1 protein.
|
| T7645 |
[Des-Arg9]-Bradykinin(2TFA) |
[Des-Arg9]-Bradykinin(2TFA) is an agonist of Bradykinin (B1) receptor.
|
| T5149 |
MC-Val-Cit-PAB |
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linke...
|
| T3503 |
MC-Val-Cit-PABC-PNP |
MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts t...
|
| T4678 |
Fmoc-Val-Cit-PAB |
Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).
|
| T6812 |
Cyclo (-RGDfK) |
Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor.
|
| T6088 |
Anidulafungin |
Anidulafungin (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.
|
| T4289 |
Mc-Val-Ala-PAB |
Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).
|
| T6013 |
Z-VAD(OMe)-FMK |
Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It inhibits cleavage of PARP, preventing apoptosis when used at 10-50 μM.
|
| T7484 |
WKYMVM |
WKYMVM is a N-formyl peptide receptor (FPR1) agonist.
|
| T2494 |
Cilengitide |
Cilengitide is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.
|
| T7513 |
Protease-Activated Receptor-2, amide |
Protease-Activated Receptor-2, amide is an agonist of PAR2 (IC50 : 10.4 M)
|
| T2691 |
Oritavancin diphosphate |
Oritavancin diphosphate is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections...
|
| T5192 |
Gap 26 |
Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
|
| T7573 |
TFLLR-NH2(2TFA) |
TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
|
| T6876 |
Liraglutide |
Liraglutide is a long-acting GLP-1 receptor agonist.
|
| T1794 |
Micafungin sodium |
Micafungin Sodium is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antif...
|
| T6135 |
Dibenzazepine |
YO-01027 is a potent γ-secretase inhibitor.
|
| T6063 |
LY411575 |
LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.3...
|
| T6005 |
Z-DEVD-FMK |
Z-DEVD-FMK is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.
|
| T7019 |
Z-IETD-FMK |
Z-IETD-FMK is a selective caspase 8 inhibitor, which has cell permeable.
|
| T8359 |
Lanreotide acetate (108736-35-2 free base) |
Lanreotide acetate is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome
|
| T6956 |
Protirelin |
Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
|
| T6813 |
Cyclo(RGDyK) |
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
|
| T3695 |
Pepstatin |
Pepstatin is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin.
|
| T6090 |
Belnacasan |
VX-765 is an orally active IL-converting enzyme/caspase-1 inhibitor.
|
| T6870 |
L-685,458 |
L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
|
| T7631 |
Eledoisin Related Peptide(2TFA) |
Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.
|
| T3501 |
Colistimethate Sodium |
Colistimethate Sodium is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options....
|
| T7623 |
PAR-4 Agonist Peptide, amide |
PAR-4 Agonist Peptide, amide(2TFA) is an agonist of proteinase-activated receptor-4 (PAR-4).
|
| T0049 |
Azlocillin sodium |
Azlocillin, an acylampicillin, is a broad-spectrum antibiotics
|
| T7575 |
[Sar1, Ile8]-Angiotensin II(3TFA) |
[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
|
| T4988 |
Boceprevir |
Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-...
|
| T6190 |
Telaprevir |
Telaprevir (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
|
| T7627 |
Adrenocorticotropic Hormone (ACTH) (4-10) |
Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
|
| T6125 |
Semagacestat |
Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).
|
| T7040 |
Angiotensin II human |
Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I conv...
|
| T7554 |
Substance P 7-11(TFA) |
Substance P 7-11(TFA) is a C-terminal fragment of Substance P .
|
| T7615 |
Xenopsin(2TFA) |
Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.
|
| T1338 |
Sucralfate |
Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
|
| T4579 |
Pentagastrin |
pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally，which can cause the secretion and synthesis of salivary proteins....
|
| T2568 |
Felypressin |
Felypressin is a synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activit...
|
| T7813 |
α-MSH |
CZEN-002 is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
|
| T1213 |
Piperacillin sodium salt |
Piperacillin binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weak...
|
| T0945 |
Cyclosporin A |
Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib...
|
| T7617 |
Neurotensin(8-13)(3TFA) |
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
|
| T0967 |
Teicoplanin |
Teicoplanin is a semisynthetic glycopeptide antibiotic, used to treat Gram-positive bacteria.
|
| T5144 |
Desmopressin acetate (16679-58-6 free base) |
Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led ...
|
| T5145 |
Oxytocin acetate (50-56-6 free base) |
Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
|
| T6437 |
Cefoperazone |
Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in t...
|
| T1218 |
Cefoperazone sodium |
Cefoperazone sodium is broad-spectrum cephalosporin with a tetrazolyl moiety, used to treat Pseudomonas infections.
|
| T4474 |
Asunaprevir |
Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
|
| T7497 |
C3a 70-77 |
C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
|
| T4232 |
VCMMAE |
VcMMAE is a drug-linker conjugate for ADC with potent antitumor activity.
|
| T2598 |
Thymopentin |
Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. THYMOPENTIN is ...
|
| T0138 |
Cefpiramide acid |
Cefpiramide is a third-generation cephalosporin antibiotic.
|
| T5015 |
Gonadorelin Acetate (33515-09-2 free base) |
Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
|
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