多肽是介于大分子蛋白质和小分子药物之间的具有调节细胞生物功能的化合物。由于其主要来源于天然多肽或者天然多肽类似物,通常情况下,其结构清楚、作用机制明确。研究表明多肽具有靶点亲和力高、疗效稳定、免疫原性低、毒副作用小、特异性强等优点。
随着生物技术与多肽合成技术的日臻成熟,越来越多的多肽药物被开发并应用于临床。因适应症广、安全性高且疗效显著,多肽药物目前已被广泛应用于肿瘤、肝炎、糖尿病、艾滋病等领域,具有广阔的开发前景。
TargetMol可为您提供 2000 多种多肽产品供科研工作者研究使用。TargetMol始终致力于服务“科研人员”,将热门的研究报道和产品推送给各位科研人员。
产品编号 | 产品名称 | ||
---|---|---|---|
T6428 | BV6 | BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. | |
T7613 | β-Casomorphin, human | β-Casomorphin, human(TFA) is an opioid receptor agonist. | |
T2692 | A40926 | Dalbavancin Impurity is effective against Gram positive bacteria. | |
T1665 | Daptomycin | Daptomycin is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA. | |
T6564 | Leupeptin Hemisulfate | Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent. | |
T7624 | DAPTA | DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities. | |
T6763 | Xevinapant | AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIA... | |
T3984 | GLP-1(7-36), amide | GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays vari... | |
T8221 | Insulin (human) | INSULIN is a polypeptide hormone that regulates the level of glucose. | |
T7828 | [Sar9,Met(O2)11]-Substance P | Bhsar-sp is an agonist of NK1 receptor. | |
T7566 | GRGDSPK | GRGDSPK is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules. | |
T1608 | ADH-1 trifluoroacetate | Exherin (ADH-1) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitivel... | |
T7570 | RGD peptide (GRGDNP) | RGD peptide GRGDNP(2TFA) is a integrin-ligand interactions inhibitor. | |
T3226 | Paritaprevir | Paritaprevir is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3... | |
T8231 | Adrenocorticotropic Hormone (ACTH) (1-39), human | Adrenocorticotropic Hormone (ACTH) (1-39), human is an agonist of melanocortin receptor. | |
T1245 | Colistin sulfate (1066-17-7 free base) | Colistin is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2. | |
T3247 | Lysozyme from chicken egg white | Lysozyme is a bactericidal enzyme present in the chicken eggwhite, and it lyses gram-positive bacteria. | |
T6006 | Romidepsin | Romidepsin is an intravenously administered histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous a... | |
T1381 | Milbemycin oxime | Milbemycin oxime is a broad spectrum antiparasitic, used as a veterinary drug. | |
T2154 | MG-132 | MG-132 is a potent cell-permeable 20S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM). | |
T6830 | Epoxomicin | Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH ca... | |
T6881 | LTX-315 | LTX-315, the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization. | |
T4547 | Grazoprevir | MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.0... | |
T8318 | BNC210 | BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression. | |
T7577 | Angiotensin III, human, mouse | Angiotensin III, human, mouse(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM). | |
T6792 | BQ-123 | BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2. | |
T5126 | Glecaprevir | Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM). | |
T7619 | OVA Peptide(257-264) | OVA Peptide 257-264 (2TFA) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb. | |
T1679 | Thiostrepton | Thiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastiti... | |
T4286 | Fmoc-Val-Ala-PAB-OH | Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD... | |
T0832 | Vancomycin hydrochloride | Vancomycin Hydrochloride is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and... | |
T1100 | Polymyxin B sulfate (1404-26-8 free base) | Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and ha... | |
T1441 | Capreomycin sulfate | Capreomycin Sulfate, a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis. | |
T1226 | Bacitracin | Bacitracin, a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis. | |
T2208 | Bacitracin Zinc | Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from M... | |
T1130 | Gramicidin | A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is ... | |
T3967 | Exendin-4 | Exendin-4 is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer ... | |
T3633 | Crenigacestat | LY3039478 is an orally bioavailable Notch inhibitor with an IC50 of ~1nM in most of the tumor cell lines tested. LY3039478 effectively inhibits mutant Notch rece... | |
T5334 | VL285 | VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins. | |
T3617 | Ivosidenib | Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits a... | |
T4S1796 | Heterophyllin B | Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regula... | |
T4102 | Goserelin acetate | Goserelin acetate is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer. | |
T7562 | β-Amyloid (31-35) | β-Amyloid 31-35(TFA) is the shortest sequence of native Amyloid-β peptide. | |
T7489 | MART-1 (26-35) (human) | MART-1 (26-35) human is amino acid residue 26 to 35 of MART-1 protein. | |
T7645 | [Des-Arg9]-Bradykinin | [Des-Arg9]-Bradykinin(2TFA) is an agonist of Bradykinin (B1) receptor. | |
T5149 | MC-Val-Cit-PAB | MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linke... | |
T3503 | MC-Val-Cit-PABC-PNP | MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts t... | |
T4678 | Fmoc-Val-Cit-PAB | Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC). | |
T6812 | Cyclo(-RGDfK) | Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor. | |
T6088 | Anidulafungin | Anidulafungin (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity. | |
T4289 | Mc-Val-Ala-PAB | Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC). | |
T6013 | Z-VAD(OMe)-FMK | Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It inhibits cleavage of PARP, preventing apoptosis when used at 10-50 μM. | |
T7484 | WKYMVM | WKYMVM is a N-formyl peptide receptor (FPR1) agonist. | |
T2494 | Cilengitide | Cilengitide is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa. | |
T7513 | Protease-Activated Receptor-2, amide | Protease-Activated Receptor-2, amide is an agonist of PAR2 (IC50 : 10.4 M) | |
T2691 | Oritavancin diphosphate | Oritavancin diphosphate is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infections... | |
T5192 | Gap 26 | Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. | |
T7573 | TFLLR-NH2 | TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM). | |
T6876 | Liraglutide | Liraglutide is a long-acting GLP-1 receptor agonist. | |
T1794 | Micafungin sodium | Micafungin Sodium is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antif... | |
T6135 | YO-01027 | YO-01027 is a potent γ-secretase inhibitor. | |
T6063 | LY-411575 | LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.3... | |
T6005 | Z-DEVD-FMK | Z-DEVD-FMK is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10. | |
T7019 | Z-IETD-FMK | Z-IETD-FMK is a selective caspase 8 inhibitor, which has cell permeable. | |
T8359 | Lanreotide acetate (108736-35-2 free base) | Lanreotide acetate is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome | |
T6956 | Protirelin | Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin. | |
T6813 | Cyclo(RGDyK) trifluoroacetate | Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. | |
T3695 | Pepstatin | Pepstatin is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin. | |
T6090 | Belnacasan | VX-765 is an orally active IL-converting enzyme/caspase-1 inhibitor. | |
T6870 | L-685458 | L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM. | |
T7631 | Eledoisin Related Peptide | Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand. | |
T3501 | Colistimethate Sodium | Colistimethate Sodium is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options.... | |
T7623 | PAR-4 Agonist Peptide, amide | PAR-4 Agonist Peptide, amide(2TFA) is an agonist of proteinase-activated receptor-4 (PAR-4). | |
T0049 | Azlocillin sodium salt | Azlocillin, an acylampicillin, is a broad-spectrum antibiotics | |
T7575 | [Sar1, Ile8]-Angiotensin II | [Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle. | |
T4988 | Boceprevir | Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-... | |
T6190 | Telaprevir | Telaprevir (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM). | |
T7627 | Adrenocorticotropic Hormone (ACTH) (4-10), human | Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor . | |
T6125 | Semagacestat | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM). | |
T7040 | Angiotensin II human | Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I conv... | |
T7554 | Substance P (7-11) | Substance P 7-11(TFA) is a C-terminal fragment of Substance P . | |
T7615 | Xenopsin | Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin. | |
T1338 | Sucralfate | Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers. | |
T4579 | Pentagastrin | pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally,which can cause the secretion and synthesis of salivary proteins.... | |
T2568 | Felypressin | Felypressin is a synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activit... | |
T7813 | α-MSH | CZEN-002 is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. | |
T1213 | Piperacillin sodium | Piperacillin binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weak... | |
T0945 | Cyclosporin A | Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhib... | |
T7617 | Neurotensin(8-13) | Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. | |
T0967 | Teicoplanin | Teicoplanin is a semisynthetic glycopeptide antibiotic, used to treat Gram-positive bacteria. | |
T5144 | Desmopressin acetate (16679-58-6 free base) | Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led ... | |
T5145 | Oxytocin acetate (50-56-6 free base) | Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor. | |
T6437 | Cefoperazone | Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in t... | |
T1218 | Cefoperazone sodium salt | Cefoperazone sodium is broad-spectrum cephalosporin with a tetrazolyl moiety, used to treat Pseudomonas infections. | |
T4474 | Asunaprevir | Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor. | |
T7497 | C3a (70-77) | C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a. | |
T4232 | VCMMAE | VcMMAE is a drug-linker conjugate for ADC with potent antitumor activity. | |
T2598 | Thymopentin | Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. THYMOPENTIN is ... | |
T0138 | Cefpiramide acid | Cefpiramide is a third-generation cephalosporin antibiotic. | |
T5015 | Gonadorelin Acetate (33515-09-2 free base) | Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions. |