多肽

多肽是介于大分子蛋白质和小分子药物之间的具有调节细胞生物功能的化合物。由于其主要来源于天然多肽或者天然多肽类似物，通常情况下，其结构清楚、作用机制明确，许多性质往往介于小分子化学药物与大分子抗体药物之间。研究表明多肽具有靶点亲和力高、疗效稳定、免疫原性低、毒副作用小、特异性强等优点。

随着生物技术与多肽合成技术的日臻成熟，越来越多的多肽药物被开发并应用于临床。因适应症广、安全性高且疗效显著，多肽药物目前已被广泛应用于肿瘤、肝炎、糖尿病、艾滋病等领域，具有广阔的开发前景。

陶素可为您提供 1000 多种多肽产品，包括大部分的上市药物肽和抗菌活性肽，除此之外还有各种肽类激素、激素类似物、酶、受体、细胞因子、标签肽等供科研工作者研究使用。

产品编号	产品名称
T6428	BV6	BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.
T7613	β-Casomorphin, human(TFA)	β-Casomorphin, human(TFA) is an opioid receptor agonist.
T2692	Dalbavancin Impurity	Dalbavancin Impurity is effective against Gram positive bacteria.
T1665	Daptomycin	Daptomycin is a cyclic lipopeptide antibiotic that inhibits GRAM-POSITIVE BACTERIA.
T6564	Leupeptin Hemisulfate	Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
T7624	DAPTA(TFA)	DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities.
T6763	AT406	AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cI...
T3984	GLP-1(7-36)	GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays var...
T8221	INSULIN	INSULIN is a polypeptide hormone that regulates the level of glucose.
T7828	Bhsar-sp	Bhsar-sp is an agonist of NK1 receptor.
T7566	GRGDSPK	GRGDSPK is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.
T1608	Exherin trifluoroacetate	Exherin (ADH-1) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitive...
T7570	RGD peptide GRGDNP(2TFA)	RGD peptide GRGDNP(2TFA) is a integrin-ligand interactions inhibitor.
T3226	Paritaprevir	Paritaprevir is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein ...
T8231	Adrenocorticotropic Hormone (ACTH) (1-39), human	Adrenocorticotropic Hormone (ACTH) (1-39), human is an agonist of melanocortin receptor.
T1245	Colistin sulfate (1066-17-7 free base)	Colistin is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
T3247	Lysozyme	Lysozyme is a bactericidal enzyme present in the chicken eggwhite, and it lyses gram-positive bacteria.
T6006	Romidepsin	Romidepsin is an intravenously administered histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous ...
T1381	Milbemycin oxime	Milbemycin oxime is a broad spectrum antiparasitic, used as a veterinary drug.
T2154	MG132	MG-132 is a potent cell-permeable 20S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).
T6830	Epoxomicin	Epoxomicin is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH c...
T6881	LTX315	LTX-315, the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.
T4547	Grazoprevir	MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0....
T8318	BNC210	BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
T7577	Angiotensin III, human, mouse(3TFA)	Angiotensin III, human, mouse(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
T6792	BQ123	BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
T5126	Glecaprevir	Glecaprevir is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).
T7619	OVA Peptide 257-264 (2TFA)	OVA Peptide 257-264 (2TFA) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.
T1679	Thiostrepton	Thiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastit...
T4286	Fmoc-Val-Ala-PAB	Fmoc-Val-Ala-PAB is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RG...
T0832	Vancomycin hydrochloride	Vancomycin Hydrochloride is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms an...
T1100	Polymyxin B sulfate (1404-26-8 free base)	Polymyxin B sulphate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and h...
T1441	Capastat sulfate	Capreomycin Sulfate, a cyclic peptide antibiotic, binds to the 70S ribosomal unit leading to inhibition of protein synthesis.
T1226	Bacitracin	Bacitracin, a mixture of related cyclic polypeptides, disrupts bacteria by interfering with cell wall and peptidoglycan synthesis.
T2208	Zinc bacitracin	Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from ...
T1130	Gramicidin	A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is...
T3967	Exendin-4	Exendin-4 is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer...
T3633	Crenigacestat	LY3039478 is an orally bioavailable Notch inhibitor with an IC50 of ~1nM in most of the tumor cell lines tested. LY3039478 effectively inhibits mutant Notch rec...
T5334	VL285	VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
T3617	Ivosidenib	Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Ivosidenib specifically inhibits ...
T4S1796	Heterophyllin B	Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regul...
T4102	Goserelin acetate	Goserelin acetate is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
T7562	β-Amyloid 31-35(TFA)	β-Amyloid 31-35(TFA) is the shortest sequence of native Amyloid-β peptide.
T7489	MART-1 (26-35) human	MART-1 (26-35) human is amino acid residue 26 to 35 of MART-1 protein.
T7645	[Des-Arg9]-Bradykinin(2TFA)	[Des-Arg9]-Bradykinin(2TFA) is an agonist of Bradykinin (B1) receptor.
T5149	MC-Val-Cit-PAB	MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this link...
T3503	MC-Val-Cit-PABC-PNP	MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts ...
T4678	Fmoc-Val-Cit-PAB	Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).
T6812	Cyclo (-RGDfK)	Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor.
T6088	Anidulafungin	Anidulafungin (LY303366) is an echinocandin derivative used as an antifungal drug. It inhibits glucan synthase activity.
T4289	Mc-Val-Ala-PAB	Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).
T6013	Z-VAD(OMe)-FMK	Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor. It inhibits cleavage of PARP, preventing apoptosis when used at 10-50 μM.
T7484	WKYMVM	WKYMVM is a N-formyl peptide receptor (FPR1) agonist.
T2494	Cilengitide	Cilengitide is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.
T7513	Protease-Activated Receptor-2, amide	Protease-Activated Receptor-2, amide is an agonist of PAR2 (IC50 : 10.4 M)
T2691	Oritavancin diphosphate	Oritavancin diphosphate is a novel semisynthetic glycopeptide antibiotic which is being developed for the treatment of serious Gram-positive bacterial infection...
T5192	Gap 26	Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.
T7573	TFLLR-NH2(2TFA)	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).
T6876	Liraglutide	Liraglutide is a long-acting GLP-1 receptor agonist.
T1794	Micafungin sodium	Micafungin Sodium is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with anti...
T6135	Dibenzazepine	YO-01027 is a potent γ-secretase inhibitor.
T6063	LY411575	LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0....
T6005	Z-DEVD-FMK	Z-DEVD-FMK is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.
T7019	Z-IETD-FMK	Z-IETD-FMK is a selective caspase 8 inhibitor, which has cell permeable.
T8359	Lanreotide acetate (108736-35-2 free base)	Lanreotide acetate is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome
T6956	Protirelin	Protirelin is a tripeptide that stimulates the release of thyrotropin and prolactin.
T6813	Cyclo(RGDyK)	Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
T3695	Pepstatin	Pepstatin is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin.
T6090	Belnacasan	VX-765 is an orally active IL-converting enzyme/caspase-1 inhibitor.
T6870	L-685,458	L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.
T7631	Eledoisin Related Peptide(2TFA)	Eledoisin Related Peptide(2TFA) is a tachykinin receptor ligand.
T3501	Colistimethate Sodium	Colistimethate Sodium is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options...
T7623	PAR-4 Agonist Peptide, amide	PAR-4 Agonist Peptide, amide(2TFA) is an agonist of proteinase-activated receptor-4 (PAR-4).
T0049	Azlocillin sodium	Azlocillin, an acylampicillin, is a broad-spectrum antibiotics
T7575	[Sar1, Ile8]-Angiotensin II(3TFA)	[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.
T4988	Boceprevir	Boceprevir is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell...
T6190	Telaprevir	Telaprevir (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
T7627	Adrenocorticotropic Hormone (ACTH) (4-10)	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
T6125	Semagacestat	Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).
T7040	Angiotensin II human	Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I con...
T7554	Substance P 7-11(TFA)	Substance P 7-11(TFA) is a C-terminal fragment of Substance P .
T7615	Xenopsin(2TFA)	Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.
T1338	Sucralfate	Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
T4579	Pentagastrin	pentagastrin is a synthetic polypeptide that has effects like gastrin when given parenterally，which can cause the secretion and synthesis of salivary proteins...
T2568	Felypressin	Felypressin is a synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activi...
T7813	CZEN-002	CZEN-002 is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
T1213	Piperacillin sodium salt	Piperacillin binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the wea...
T0945	Cyclosporin A	Cyclosporine A is a Calcineurin Inhibitor Immunosuppressant. The mechanism of action of cyclosporine is as a Calcineurin Inhibitor, and Cytochrome P450 3A4 Inhi...
T7617	Neurotensin(8-13)(3TFA)	Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
T0967	Teicoplanin	Teicoplanin is a semisynthetic glycopeptide antibiotic, used to treat Gram-positive bacteria.
T5144	Desmopressin acetate (16679-58-6 free base)	Desmopressin is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led...
T5145	Oxytocin acetate (50-56-6 free base)	Oxytocin is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.
T6437	Cefoperazone	Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in ...
T1218	Cefoperazone sodium	Cefoperazone sodium is broad-spectrum cephalosporin with a tetrazolyl moiety, used to treat Pseudomonas infections.
T4474	Asunaprevir	Asunaprevir is an effective hepatitis C virus (HCV) NS3 protease inhibitor.
T7497	C3a 70-77	C3a 70-77 is an octapeptide corresponding to the COOH terminus of C3a.
T4232	VCMMAE	VcMMAE is a drug-linker conjugate for ADC with potent antitumor activity.
T2598	Thymopentin	Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. THYMOPENTIN is...
T0138	Cefpiramide acid	Cefpiramide is a third-generation cephalosporin antibiotic.
T5015	Gonadorelin Acetate (33515-09-2 free base)	Gonadorelin Acetate is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.