T68673
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Others
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Amsacrine gluconate is an aminoacridine derivative with potential antineoplastic activity. Although its mechanism of action is incompletely defined, amsacrine may intercalate into DNA and inhibit topoisomerase II, resulting in DNA double-strand breaks, arrest of the S/G2 phase of the cell cycle, and cell death. |
T68671
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Others
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Amsacrine Isothionate is an aminoacridine derivative with potential antineoplastic activity. Although its mechanism of action is incompletely defined, amsacrine may intercalate into DNA and inhibit topoisomerase II, resulting in DNA double-strand breaks, arrest of the S/G2 phase of the cell cycle, and cell death. |
T5820
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Topoisomerase
Autophagy
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Amsacrine hydrochloride (acridinyl anisidide hydrochloride) 是一种拓扑异构酶 II 抑制剂,用于治疗急性髓细胞性白血病。 |
T1206
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Potassium Channel
Topoisomerase
Autophagy
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Amsacrine (AMSA) 是一种抗肿瘤剂,可以嵌入到肿瘤细胞的 DNA 中。它还表达拓扑异构酶抑制剂活性,特异性抑制拓扑异构酶 II。 |
T68672
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Others
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Amsacrine lactate is an aminoacridine derivative with potential antineoplastic activity. Although its mechanism of action is incompletely defined, amsacrine may intercalate into DNA and inhibit topoisomerase II, resulting in DNA double-strand breaks, arrest of the S/G2 phase of the cell cycle, and cell death. |