|
TMPY-04123
|
CEACAM1 Protein, Human, Recombinant (His & hFc)
|
Human
|
HEK293 Cells
|
|
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
|
|
TMPJ-00865
|
VEGF121 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessels and endothelial cell growth, increasing microvascular permeability, promoting cell migration and inhibiting apoptosis. Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms. The lymphangiogenesis may be promoted by upregulation of VEGF121, which may in turn act in part via induction of VEGF-C. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
|
|
TMPY-03698
|
VEGF121b Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9.
|
|
TMPY-06036
|
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
|
Human
|
HEK293 Cells
|
|
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
|
|
TMPH-00005
|
YAP1 Protein, Human, Recombinant (Isoform 9, His)
|
Human
|
P. pastoris (Yeast)
|
|
YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.4 kDa; 80 kDa, reducing conditions and the accession number is P46937-9.
|
|
TMPY-06986
|
FGF-8b Protein, Human, Recombinant
|
Human
|
E. coli
|
|
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning.
|
|
TMPY-00132
|
Mesothelin Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
|
|
TMPY-04935
|
CD47 Protein, Human, Recombinant (aa 1-139, His)
|
Human
|
HEK293 Cells
|
|
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
|
|
TMPY-03763
|
Neuropilin-2 Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
|
|
TMPY-05191
|
CD47 Protein, Human, Recombinant, Biotinylated
|
Human
|
HEK293 Cells
|
|
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
|
|
TMPY-00072
|
GITR/TNFRSF18 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
|
|
TMPY-04683
|
CD47 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
|
|
TMPY-00892
|
Neuropilin-2 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
|
|
TMPY-01897
|
PRSS3 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3 / PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma.
|
|
TMPY-01020
|
Periostin/OSF-2 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
|
|
TMPY-04142
|
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
|
|
TMPY-05748
|
CD45 Protein, Human, Recombinant (aa 26-577, His)
|
Human
|
HEK293 Cells
|
|
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
|
|
TMPY-01180
|
CD86 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
|
|
TMPJ-01099
|
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
|
Human
|
HEK293 Cells
|
|
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.
|
|
TMPY-00357
|
HNT/NTM Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
|
|
TMPY-04298
|
CDCP1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
|
|
TMPY-00480
|
NCAM1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
|
|
TMPY-00891
|
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
|
Human
|
HEK293 Cells
|
|
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
|
|
TMPY-02096
|
TACI Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
|
|
TMPY-04113
|
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
|
|
TMPY-02011
|
CD96 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
|
|
TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are involved in the development of glioma (GLM). Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas , and ependymomas. DMBT1 may be considered as a candidate tumor suppressor for brain, lung, esophageal, gastric, and colorectal cancers. It may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. DMBT1 may play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. It may be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. DMBT1 may function as a binding protein in saliva for the regulation of taste sensation. It binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission.
|
|
TMPY-01717
|
VEGF164 Protein, Mouse, Recombinant
|
Mouse
|
Baculovirus Insect Cells
|
|
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
|
|
TMPY-00341
|
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
|
Human
|
HEK293 Cells
|
|
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
|
|
TMPY-01613
|
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
|
|
TMPJ-00850
|
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
|
Mouse
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
|
|
TMPY-03527
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
|
Human
|
HEK293 Cells
|
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa and the accession number is O14788-2.
|
|
TMPY-00701
|
CD16b Protein, Human, Recombinant (NA2, HEK293, His)
|
Human
|
HEK293 Cells
|
|
CD16b Protein, Human, Recombinant (NA2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2.
|
|
TMPY-01691
|
Clusterin Protein, Human, Recombinant (CLU34, His)
|
Human
|
HEK293 Cells
|
|
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
|
|
TMPY-00751
|
TrkB Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
|
|
TMPY-05288
|
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
|
Human
|
E. coli
|
|
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
|
|
TMPY-04844
|
BTN3A1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
|
|
TMPY-06056
|
KRAS Protein, Human, Recombinant (G12D, His)
|
Human
|
E. coli
|
|
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
|
|
TMPY-02820
|
SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)
|
Human
|
E. coli
|
|
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
|
|
TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
|
Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity and tau phosphorylation. c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. The c-Abl protein is a ubiquitously expressed nonreceptor tyrosine kinase involved in the development and function of many mammalian organ systems, including the immune system and bone. It regulates the cellular response to TAM through functional interaction with the estrogen receptor, which suggests c-Abl as a therapeutic target and a prognostic tumor marker for breast cancer. c-Abl also plays a key role in signaling chemokine-induced T-cell migration. In addition, c-Abl contains NLSs (nuclear localization signals) and DNA-binding sequences important for nuclear functions. c-Abl has become an important therapeutic target in human chronic myeloid leukaemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
|
|
TMPY-01935
|
c-Kit Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
|
|
TMPY-04644
|
PDGFB Protein, Human, Recombinant (His)
|
Human
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.
|
|
TMPY-01985
|
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human
|
HEK293 Cells
|
|
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
|
|
TMPY-04356
|
GSK3B Protein, Human, Recombinant (His)
|
Human
|
Baculovirus Insect Cells
|
|
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
|
|
TMPY-02500
|
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
|
|
TMPY-05414
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
|
Mouse
|
Baculovirus Insect Cells
|
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
|
|
TMPY-01871
|
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
|
Human
|
HEK293 Cells
|
|
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
|
|
TMPY-02792
|
GDNF Protein, Human, Recombinant (HEK293)
|
Human
|
HEK293 Cells
|
|
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
|
|
TMPY-01359
|
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
|
|
TMPY-01888
|
KRAS Protein,Human, Recombinant (Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
|
沪公网安备 31010602004043号
