目录号 | 产品详情 | 靶点 | |
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T0926 | Others DNA/RNA Synthesis Endogenous Metabolite | ||
Azelaic acid (Anchoic acid) 是头发和皮肤调理剂的组分,可由油酸臭氧分解产生。Azelaic acid 通过抑制微生物细胞原蛋白合成对痤疮丙酸杆菌和表皮葡萄球菌具有抑菌活性。Azelaic acid 还具有抑制色素沉着的功能,这是由于其清除自由基作用。 | |||
T3321 | HIV Protease | ||
Oleanonic acid (3-Ketooleanolic Acid) 是一种三萜,可以抑制 HIV-1 对细胞的感染。它具有保肝作用,并具有抗肿瘤和抗病毒特性。 | |||
T0755 | Others | ||
Carglumic Acid (Ureidoglutaric acid) 是一种 N-乙酰谷氨酸 (NAG) 的功能类似物和氨甲酰磷酸合成酶 1(CPS1)的活化剂,可用于与 N-乙酰谷氨酸合成酶 (NAGS) 缺陷相关的急性和慢性高氨血症的研究。 | |||
T4944 | Endogenous Metabolite | ||
Nervonic acid (Selacholeic acid) 是在髓磷脂生物合成中很重要的单不饱和脂肪酸。 | |||
T21367 | Endogenous Metabolite | ||
Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) 是一种维生素 B9 衍生物,是生物体常见的一碳供体,参与生物体生长代谢。 | |||
TN6945 | Others | ||
Lactic acid (2-hydroxypropanoic acid) 是糖酵解的产物,广泛存在与自然界中。Lactate acid 在体内收缩骨骼肌缺氧时会产生,可在完全有氧条件下被去除。Lactic acid 可作为危重病人的血流动力学指标。Lactic acid 具有抗肿瘤活性。 | |||
T5369 | Others Endogenous Metabolite | ||
Docosahexaenoic Acid 是一种ω-3脂肪酸,在脑和视网膜中较为丰富,且能够直接从鱼油和母乳中获得。 | |||
T4819 | Others Endogenous Metabolite Antibacterial | ||
Pipecolic acid (2-Piperidinecarboxylic acid) 是一种赖氨酸代谢物,是许多微生物次级代谢物的重要前体,可用作吡哆醇依赖性癫痫的诊断标记。 | |||
T3982 | Others | ||
Vulpinic Acid (Pulvinic acid methyl ester) 是地衣代谢物,可降低人脐静脉内皮细胞 (HUVEC) 中 H2O2诱导的ROS,氧化应激和氧化应激相关损伤,可作用于厌氧菌、葡萄球菌及肠球菌。它对脉粥样硬化的研究具有潜在的价值。 | |||
T4810 | Others Endogenous Metabolite | ||
Pyrocatechuic acid (Catecholcarboxylic acid) 是一种存在于血浆中的苯甲酸代谢物,当摄入阿司匹林后,它的含量会提高。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-02131 | Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) | Human | E. coli | ||
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphorylate activated PDGF receptor, thus modulating PDGF-induced mitogenesis. In vitro, LMW-PTP was found to efficiently dephosphorylate activated FcgammaRIIA and LAT, but not Syk or phospholipase Cgamma2. The overexpression of LMW-PTP inhibited activation of Syk downstream of FcgammaRIIA and reduced intracellular Ca(2+) mobilization. It been demonstrated that LMW-PTP is responsible for FcgammaRIIA dephosphorylation, and is implicated in the down-regulation of cell activation mediated by this ITAM-bearing immunoreceptor. In addition, ACP1 is a highly polymorphic phosphatase that is especially abundant in the central nervous system and is known to be involved in several signal transduction pathways.
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TMPY-02155 | Prostatic Acid Phosphatase Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2.
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TMPY-05526 | Siglec-15 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Siglec-15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q6ZMC9-1.
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TMPY-02672 | Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
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TMPY-02585 | Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells | ||
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) in length as the pro form, while Isoform 2 and isoform 3 have lost catalytic activity. The active SMPD1 isoform 1 contains one saposin B-type domain that likely interacts with sphingomyelin, and a catalytic region. Human SMPD1 is 86% aa identical to mouse SMPD1. SMPD1 is a monomeric lysosomal enzyme that converts sphingomyelin (a plasma membrane lipid ) into ceramide through the removal of phosphorylcholine. This generates second messenger components that participate in signal transduction. Defects in SMPD1 are the cause of Niemann-Pick disease type A (NPA) and type B (NPB), also known as Niemann-Pick disease classical infantile form and Niemann-Pick disease visceral form. Niemann-Pick disease is a clinically and genetically heterogeneous recessive disorder. NPB has little if any neurologic involvement and patients may survive into adulthood.
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TMPY-05658 | Siglec-10 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Siglec-10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.5 kDa and the accession number is AAI01726.1.
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TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
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TMPY-05099 | GBA/glucocerebrosidase Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD.
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TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
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TMPY-06686 | FASN Protein, Mouse, Recombinant (His) | Mouse | E. coli | ||
FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096.
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TMPJ-01073 | FABP5 Protein, Human, Recombinant (His) | Human | E. coli | ||
Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP5 can be expressed in keratinocytes, and is highly expressed in psoriatic skin. FABP5 has been shown to be involved in keratinocyte differentiation. FABP5 has high specificity for fatty acids, the highest affinity for C18 chain length. FABP5 can decrease the chain length or introduce double bonds to reduce the affinity.
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TMPJ-00520 | NANS Protein, Human, Recombinant (His) | Human | E. coli | ||
Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
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TMPJ-00908 | LMW-PTP Protein, Human, Recombinant (His) | Human | E. coli | ||
Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of the PDGF receptor. In addition, LMW-PTP plays an important role in the regulation of physiological functions, such as stress resistance and synthesis of the polysaccharide capsule.
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TMPJ-00785 | FABP3 Protein, Human, Recombinant (His) | Human | E. coli | ||
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. The FABP3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is also a candidate tumor suppressor gene for human breast cancer. FABP3 is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of onset of pain.
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TMPJ-00853 | DAO Protein, Human, Recombinant (His) | Human | E. coli | ||
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups.
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TMPY-00960 | ACP5 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
ACP5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024R7F8.
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TMPY-01414 | ACP5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
ACP5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q05117.
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TMPJ-00869 | GLB1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 100 mutations have been identified for β Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
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TMPY-06683 | FASN Protein, Human, Recombinant (His) | Human | E. coli | ||
FASN Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.26 kDa and the accession number is P49327.
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TMPY-00190 | ULBP-6 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells | ||
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is AAK91503.1.
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TMPY-05678 | Siglec-15 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells | ||
Siglec-15 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53 kDa and the accession number is A0A2K5UY47.
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TMPY-01060 | DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells | ||
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q53Y41.
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TMPH-00880 | ASAH1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
ASAH1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 58.7 kDa and the accession number is Q13510.
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TMPY-02472 | DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells | ||
DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55.2 kDa and the accession number is O88533.
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TMPY-00575 | ULBP-6 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa and the accession number is AAK91503.1.
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TMPH-03434 | BIO3 Protein, S. cerevisiae, Recombinant (His & Myc) | Saccharomyces cerevisiae | E. coli | ||
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor. BIO3 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.7 kDa and the accession number is P50277.
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TMPJ-00671 | FABP7 Protein, Human, Recombinant (His) | Human | E. coli | ||
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP7 is predominately expressed in brain and neural tissues. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. FABP7 plays a critical role in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. FABP7 is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
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TMPY-03278 | SMPDL3A Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
SMPDL3A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is Q92484.
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TMPY-01878 | L-FABP Protein, Human, Recombinant (His) | Human | E. coli | ||
Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP1 and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. FABP1 / FABPL binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. It forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. FABP1 / FABPL may be involved in intracellular lipid transport.
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TMPJ-00426 | Siglec-5 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells | ||
Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a 439aa extracellular domain (ECD) with three Ig-like domains, a transmembrane region and a cytoplasma tail. No Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
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TMPH-02490 | ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) | Mouse | E. coli | ||
ASAH1 Protein, Mouse, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10XHis-GST and C-Myc tag. The predicted molecular weight is 43.8 kDa and the accession number is Q9WV54.
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TMPH-03276 | DAO Protein, Rat, Recombinant (His & Myc) | Rat | E. coli | ||
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.8 kDa and the accession number is O35078.
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TMPY-00367 | Chemerin/RARRES2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
Chemerin/RARRES2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q9DD06.
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TMPY-01549 | CRABP2 Protein, Human, Recombinant (His) | Human | E. coli | ||
CRABP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.5 kDa and the accession number is P29373.
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TMPH-02621 | DAO Protein, Mouse, Recombinant (His) | Mouse | E. coli | ||
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.7 kDa and the accession number is P18894.
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TMPY-04623 | PRRG2 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells | ||
The genes encoding a family of proteins termed proline-rich gamma-carboxyglutamic acid (PRRG) proteins were identified and characterized more than a decade ago. These novel membrane proteins have an extracellular gamma-carboxyglutamic acid (Gla) protein domain and cytosolic WW binding motifs. Several of the PRRG-interacting proteins are essential for a variety of physiologic processes.
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TMPY-04143 | Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells | ||
Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.6 kDa and the accession number is Q9DD06.
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TMPY-02952 | SIAE Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells | ||
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.
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TMPY-02051 | FABP2 Protein, Human, Recombinant (His) | Human | E. coli | ||
Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP family proteins could be used as tissue specific injury marker based on the following characteristics of FABP. The intestinal fatty acid binding protein (I-FABP), or fatty acid-binding protein 2 (FABP2), an intracellular protein expressed only in the intestine, involved in the absorption and intracellular transport of dietary long chain fatty acids. The FABP2 gene is proposed as a candidate gene for diabetes because the protein it codes is involved in fatty acid (FA) absorption and metabolism. Numerous studies have assessed FABP2 gene variants. A transition of G to A at codon 54 of FABP2 results in an amino acid substitution (Ala54 to Thr54), which is common in diverse populations and results in increased FA absorption in vivo. Some evidence indicates that this variant may be associated with type 2 diabetes. This polymorphism was associated with some cardiovascular risk factors. The cytosolic human intestinal fatty acid binding protein (hFABP2) is proposed to be involved in intestinal absorption of long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
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TMPY-02189 | CRABP2 Protein, Mouse, Recombinant (His) | Mouse | E. coli | ||
CRABP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.1 kDa and the accession number is P22935.
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TMPH-01525 | CMAHP Protein, Human, Recombinant (His & Myc) | Human | E. coli | ||
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates. However, it may play a role in Wnt signaling.
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TMPH-00126 | Aspergillopepsin-2 Protein, Aspergillus niger, Recombinant (His & SUMO) | Aspergillus niger | E. coli | ||
N/A. Aspergillopepsin-2 Protein, Aspergillus niger, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.9 kDa and the accession number is P24665.
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TMPH-00573 | DAPA aminotransferase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli | ||
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Complements a bioU deletion in Synechocystis PCC 6803.
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TMPY-03307 | CD98 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells | ||
CD98 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.7 kDa and the accession number is Q794F9.
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TMPY-04631 | CD98 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells | ||
CD98 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.8 kDa and the accession number is Q794F9.
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TMPY-05835 | Siglec-15 Protein, Mouse, Recombinant (rFc) | Mouse | HEK293 Cells | ||
Siglec-15 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 50.83 kDa and the accession number is A7E1W8.
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TMPH-01183 | CYP26B1 Protein, Human, Recombinant (His) | Human | E. coli | ||
CYP26B1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.5 kDa and the accession number is Q9NR63.
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TMPY-03864 | CRABP1 Protein, Human, Recombinant | Human | E. coli | ||
CRABP1 is a specific binding protein for a vitamin A family member. It is thought that CRABP1 plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. It forms a beta-barrel structure which accommodates hydrophobic ligands in its interior.
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TMPY-01579 | GBA3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells | ||
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
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TMPJ-00938 | 4HPPD Protein, Human, Recombinant (His) | Human | E. coli | ||
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.
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