目录号 | 产品详情 | 靶点 | |
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T0510 | Antibacterial Antibiotic Autophagy | ||
Sulfaguanidine (Guanicil) 是一种具有口服活性的磺胺类抗菌剂和抗生素。它可用于肠道感染,例如细菌性痢疾的研究。 | |||
T6179 | Antibacterial Antibiotic | ||
Moxalactam sodium salt (LY-127935) 是一种抗生素, 对大肠杆菌和绿脓杆菌有作用。 | |||
TP1309 | Antibacterial Antibiotic | ||
Gastric mucin 是一种能保护胃肠道免受酸、蛋白酶、致病微生物和机械创伤影响的糖蛋白。 | |||
T3S0137 | Antibacterial Antibiotic | ||
Bavachalcone 是从补骨脂中分离的化合物,广泛用于中药,具有抗生素和抗癌等活性。 | |||
T8063 | Others Antibacterial Antibiotic | ||
Cephapirin Benzathine 是头孢哌啶的苄硫醚盐形式,是一种广谱抗生素。 | |||
T6803 | Histone Methyltransferase Antibacterial Antibiotic | ||
Chaetocin 特异性抑制组蛋白甲基转移酶(HMT) SU(VAR)3-9,IC50值为0.6 μM。它还可抑制硫氧还蛋白还原酶,IC50值为4 μM。 | |||
T125208 | |||
Antibiotic WB 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125208,CAS号为 247919-66-0。 | |||
T1550 | Antibacterial Antibiotic | ||
Thiamphenicol (Dextrosulphenidol) 是 Chloramphenicol 的甲基磺酰基衍生物,是一种广谱抗菌类抗生素。它与 50S 核糖体亚基结合,抑制蛋白质合成并具有抑菌作用 ,特别针对革兰氏阴性,革兰氏阳性需氧和厌氧菌。 | |||
T125527 | |||
Antibiotic 2158 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125527。 | |||
T1070 | Antibacterial Antibiotic | ||
Cefmetazole sodium (Sodium cefmetazole) 是具有广谱抗菌活性的半合成头孢霉素抗生素。它通过与青霉素结合蛋白结合,阻止肽聚糖的交联,导致细胞壁完整性的丧失。它可研究妇科、腹腔内、尿道、呼吸道和皮肤和软组织感染。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-00672 | Azurocidin/CAP37 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced. Neutrophils arriving first at sites of inflammation release Azurocidin, which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. It thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions.
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TMPH-00639 | Hygromycin-B 4-O-kinase Protein, E. coli, Recombinant (His) | E. coli | E. coli | ||
The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin.
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TMPH-00027 | Aculeacin-A acylase Protein, Actinoplanes utahensis, Recombinant (His & SUMO) | Actinoplanes utahensis | E. coli | ||
Catalyzes the hydrolysis of the palmitoyl moiety of the antifungal antibiotic, aculeacin-A, giving a hexapeptide moiety and a long chain fatty acid. Aculeacin-A acylase Protein, Actinoplanes utahensis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.1 kDa and the accession number is P29958.
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TMPJ-00611 | SFP Protein, B.subtilis, Recombinant (His) | Bacillus subtilis | E. coli | ||
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
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TMPY-01812 | Enoyl-ACP Reductase Protein, E. coli, Recombinant (His) | E. coli | E. coli | ||
Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI subfamily. Microorganisms produce many kinds of antibiotics which function in an antagonistic capacity in nature where they have much competition. Bacterial FAS provides essential fatty acids for use in the assembly of key cellular components. Among them, FABI is an enoyl-ACP reductase which catalyzes the final and rate-limiting step of bacterial FAS. The antibiotic diazaborine interferes with the activity by binding to the protein. FABI is a potential target for selective antibacterial action, because it shows low overall sequence homology with mammalian enzymes. Various compounds have been reported as inhibitors of bacterial FabI-inhibitory compounds.
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TMPY-01679 | LCN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been found in the rat, pig, and probably dog and horse. Lipocalin-1 / VEGP is an unusual lipocalin member, because of its high promiscuity for relative insoluble lipids and binding characteristics that differ from other members. Lipocalin-1 / VEGP acts as the principal lipid-binding protein in tear fluid, a more general physiological function has to be proposed due to its wide distribution and properties. Lipocalin-1 / VEGP would be ideally suited for scavenging of lipophilic, potentially harmful substances and thus might act as a general protection factor of epithelia. Lipocalin-1 / LCN1 could play a role in taste reception. It could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Lipocalin-1 / LCN1 can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. It exhibits an extremely wide ligand pocket.
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