目录号 | 产品详情 | 靶点 | |
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T23741 | |||
Antibiotic JI 20A is a bioactive chemical. | |||
T7096 | Antibacterial Antibiotic | ||
Tildipirosin 是一种具有长效抗菌作用的大环内酯抗生素。 | |||
T5022 | Antibacterial Antibiotic | ||
Ceforanide 是一种头孢菌素,可静脉或肌肉给药。它在体外具有一系列抗菌活性。 | |||
T25094 | |||
Antibiotic K 4 is an inhibitor of angiotensin I converting enzyme produced by Actinomadura spiculosospora. | |||
T16073 | Others Antibacterial | ||
Micronomicin (Gentamicin C2b) 是一种具有抗菌和杀菌能力的抗生素。 | |||
T22262 | Microtubule Associated | ||
Ansamitocin p-3 (Maytansinol isobutyrate) 是一种微管抑制剂,对微管蛋白聚合的 IC50 为 3.4 μM。 | |||
T19709 | Others | ||
Nitrocefin 是 β-内酰胺酶的显色底物,当 β-内酰胺酶将 β-内酰胺环中的酰胺键水解后,Nitrocefin 的颜色会由黄色变为红色。它可用于 β-内酰胺酶耐药抗生素的研究。 | |||
T8302 | Antibacterial Antibiotic | ||
Ceftiofur 是一种半合成抗生素,对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。 | |||
TP1329 | Antibacterial Antibiotic | ||
Nisin 是乳酸链球菌肽,由一组属于乳球菌和链球菌属的革兰氏阳性菌产生。 | |||
T8340 | Others Antibacterial Antibiotic | ||
Quinocetone 是一种合成的强效抗菌剂,可用于提高饲料用动物饲料效率和控制痢疾。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-00672 | Azurocidin/CAP37 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced. Neutrophils arriving first at sites of inflammation release Azurocidin, which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. It thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions.
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TMPH-00639 | Hygromycin-B 4-O-kinase Protein, E. coli, Recombinant (His) | E. coli | E. coli | ||
The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin.
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TMPH-00027 | Aculeacin-A acylase Protein, Actinoplanes utahensis, Recombinant (His & SUMO) | Actinoplanes utahensis | E. coli | ||
Catalyzes the hydrolysis of the palmitoyl moiety of the antifungal antibiotic, aculeacin-A, giving a hexapeptide moiety and a long chain fatty acid. Aculeacin-A acylase Protein, Actinoplanes utahensis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.1 kDa and the accession number is P29958.
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TMPJ-00611 | SFP Protein, B.subtilis, Recombinant (His) | Bacillus subtilis | E. coli | ||
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
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TMPY-01812 | Enoyl-ACP Reductase Protein, E. coli, Recombinant (His) | E. coli | E. coli | ||
Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI subfamily. Microorganisms produce many kinds of antibiotics which function in an antagonistic capacity in nature where they have much competition. Bacterial FAS provides essential fatty acids for use in the assembly of key cellular components. Among them, FABI is an enoyl-ACP reductase which catalyzes the final and rate-limiting step of bacterial FAS. The antibiotic diazaborine interferes with the activity by binding to the protein. FABI is a potential target for selective antibacterial action, because it shows low overall sequence homology with mammalian enzymes. Various compounds have been reported as inhibitors of bacterial FabI-inhibitory compounds.
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TMPY-01679 | LCN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been found in the rat, pig, and probably dog and horse. Lipocalin-1 / VEGP is an unusual lipocalin member, because of its high promiscuity for relative insoluble lipids and binding characteristics that differ from other members. Lipocalin-1 / VEGP acts as the principal lipid-binding protein in tear fluid, a more general physiological function has to be proposed due to its wide distribution and properties. Lipocalin-1 / VEGP would be ideally suited for scavenging of lipophilic, potentially harmful substances and thus might act as a general protection factor of epithelia. Lipocalin-1 / LCN1 could play a role in taste reception. It could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Lipocalin-1 / LCN1 can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. It exhibits an extremely wide ligand pocket.
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