|
TMPY-00891
|
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
|
Human
|
HEK293 Cells
|
|
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
|
|
TMPY-02096
|
TACI Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
|
|
TMPY-04113
|
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
|
|
TMPY-02011
|
CD96 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
|
|
TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are involved in the development of glioma (GLM). Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas , and ependymomas. DMBT1 may be considered as a candidate tumor suppressor for brain, lung, esophageal, gastric, and colorectal cancers. It may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. DMBT1 may play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. It may be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. DMBT1 may function as a binding protein in saliva for the regulation of taste sensation. It binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission.
|
|
TMPY-01717
|
VEGF164 Protein, Mouse, Recombinant
|
Mouse
|
Baculovirus Insect Cells
|
|
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
|
|
TMPY-00341
|
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
|
Human
|
HEK293 Cells
|
|
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
|
|
TMPY-01613
|
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
|
|
TMPJ-00850
|
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
|
Mouse
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
|
|
TMPY-03527
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc)
|
Human
|
HEK293 Cells
|
|
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 47.9 kDa and the accession number is O14788-2.
|
|
TMPY-00701
|
CD16b Protein, Human, Recombinant (NA2, HEK293, His)
|
Human
|
HEK293 Cells
|
|
CD16b Protein, Human, Recombinant (NA2, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2.
|
|
TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
|
Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity and tau phosphorylation. c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. The c-Abl protein is a ubiquitously expressed nonreceptor tyrosine kinase involved in the development and function of many mammalian organ systems, including the immune system and bone. It regulates the cellular response to TAM through functional interaction with the estrogen receptor, which suggests c-Abl as a therapeutic target and a prognostic tumor marker for breast cancer. c-Abl also plays a key role in signaling chemokine-induced T-cell migration. In addition, c-Abl contains NLSs (nuclear localization signals) and DNA-binding sequences important for nuclear functions. c-Abl has become an important therapeutic target in human chronic myeloid leukaemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
|
|
TMPY-01935
|
c-Kit Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
|
|
TMPY-04644
|
PDGFB Protein, Human, Recombinant (His)
|
Human
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.3 kDa and the accession number is P01127-2.
|
|
TMPY-01985
|
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human
|
HEK293 Cells
|
|
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
|
|
TMPY-02500
|
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
|
|
TMPY-05414
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
|
Mouse
|
Baculovirus Insect Cells
|
|
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
|
|
TMPY-04424
|
MST3 Protein, Human, Recombinant (His)
|
Human
|
Baculovirus Insect Cells
|
|
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury.
|
|
TMPY-04356
|
GSK3B Protein, Human, Recombinant (His)
|
Human
|
Baculovirus Insect Cells
|
|
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
|
|
TMPY-01588
|
ALDH7A1 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.
|
|
TMPY-01691
|
Clusterin Protein, Human, Recombinant (CLU34, His)
|
Human
|
HEK293 Cells
|
|
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
|
|
TMPY-00751
|
TrkB Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
|
|
TMPY-05288
|
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
|
Human
|
E. coli
|
|
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
|
|
TMPY-04844
|
BTN3A1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
|
|
TMPY-06056
|
KRAS Protein, Human, Recombinant (G12D, His)
|
Human
|
E. coli
|
|
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
|
|
TMPY-02820
|
SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)
|
Human
|
E. coli
|
|
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
|
|
TMPY-02695
|
IgG2b Protein, Mouse, Recombinant
|
Mouse
|
HEK293 Cells
|
|
IgG2b Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.3 kDa and the accession number is P01867-2.
|
|
TMPY-02597
|
IL-37 Protein, Human, Recombinant
|
Human
|
E. coli
|
|
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression in murine and human cells, it has been demonstrated that the ability of adenovirus-mediated gene transfer of IL1F7 to induce an IL-12- and Fas ligand-dependent anti-tumor response. Complete inhibition of tumor growth was observed following multiple injections of IL1F7 in most animals. These results suggest that IL1F7 could play a role in both innate and adaptive immune responses, similar to IL-18. Moreover, IL1F7 could be useful for cancer gene therapy.
|
|
TMPY-02211
|
USP5 Protein, Human, Recombinant (His)
|
Human
|
Baculovirus Insect Cells
|
|
Ubiquitin carboxyl-terminal hydrolase 5, also known as Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thiolesterase 5, Ubiquitin-specific-processing protease 5, ISOT and USP5, is a member of the peptidase C19 family. USP5 contains 2 UBA domains and one UBP-type zinc finger. The UBP-type zinc finger domain interacts selectively with an unmodified C-terminus of the proximal ubiquitin. Both UBA domains are involved in polyubiquitin recognition. The UBP-type zinc finger domain crystallizes as a dimer linked by a disulfide bond between the Cys-195 residues of both molecules, but there is no evidence that the full-length USP5 exists as a dimer. USP5 cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. USP5 is involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. It binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
|
|
TMPY-01871
|
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
|
Human
|
HEK293 Cells
|
|
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
|
|
TMPY-01359
|
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
|
|
TMPY-01888
|
KRAS Protein,Human, Recombinant (Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
|
|
TMPY-00747
|
Nectin-2 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
|
|
TMPY-04051
|
c-Kit Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
|
|
TMPY-05427
|
CD19 Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
|
|
TMPJ-00335
|
TGFBR2 Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
|
|
TMPY-00127
|
M-CSF/CSF1 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
|
|
TMPY-02906
|
CD16b Protein, Human, Recombinant (NA2, CHO, His)
|
Human
|
CHO Cells
|
|
CD16b Protein, Human, Recombinant (NA2,His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 22.2 kDa and the accession number is O75015.2.
|
|
TMPY-02792
|
GDNF Protein, Human, Recombinant (HEK293)
|
Human
|
HEK293 Cells
|
|
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
|
|
TMPY-04116
|
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
|
Human
|
E. coli
|
|
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
|
|
TMPY-02432
|
VEGF164 Protein, Rat, Recombinant
|
Rat
|
Baculovirus Insect Cells
|
|
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
|
|
TMPY-02231
|
TrkB Protein, Mouse, Recombinant (His)
|
Mouse
|
HEK293 Cells
|
|
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
|
|
TMPY-00850
|
ST2/IL-1 RL1 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
|
|
TMPY-02367
|
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
|
Human
|
HEK293 Cells
|
|
Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
|
|
TMPY-00849
|
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
|
|
TMPY-00871
|
LAYN Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
|
|
TMPY-01199
|
CD74 Protein, Human, Recombinant (His)
|
Human
|
HEK293 Cells
|
|
CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
|
|
TMPY-02971
|
CLEC10A Protein, Human, Recombinant (hFc)
|
Human
|
HEK293 Cells
|
|
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
|
|
TMPY-05586
|
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human
|
HEK293 Cells
|
|
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.3 kDa and the accession number is Q96BF3-2.
|
|
TMPY-00748
|
Nectin-2 Protein, Human, Recombinant
|
Human
|
HEK293 Cells
|
|
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
|
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