T23018
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Others
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competitive antagonist at P2Y1 receptors |
T28099
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Others
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MRS2179 is a competitive P2Y1 receptor antagonist (Kb = 100 nM) with no appreciable activity at P2Y2, P2Y4, or P2Y6 at concentrations up to 30 µM, or at P2Y12 and P2Y13. It inhibits ADP-induced platelet shape change and aggregation (pA2 = 6.55) in vitro a |
T64078
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Others
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MRS2179 tetrasodium hydrate 是 P2Y1 受体的竞争性拮抗剂,能够作用于火鸡 P2Y1 受体 (Kb: 102 nM, pA2: 6.99),对血小板聚集表现出抑制作用。MRS2179 tetrasodium hydrate 对 P2Y1 的选择性高于 P2X1 (IC50: 1.15 μM)、P2X3 (IC50: 12.9 μM)、P2X2、P2X4、P2Y2、P2Y4 和 P2Y6 受体。 |