目录号 | 产品详情 | 靶点 | |
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TN4080 | Xanthine Oxidase | ||
Fraxamoside is a xanthine oxidase inhibitor (XOI) comparable in potency in vitro to the standard antigout drug allopurinol. It shows significant free radical scavenging effect against DPPH(EC50=62.6 uM). | |||
T69282 | |||
Febuxostat 67M-2 is a derivative compound of Febuxostat 67M-1 which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation. | |||
T26589 | |||
Albifylline is a xanthine derivates with anti-asthmatic activity. Albifylline may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. Albifylline also improves microvascula | |||
T32905 | |||
LSPN451 is an effective xanthine oxidase inhibitor and may be used to treat hyperuricemia and gout. | |||
T71447 | |||
Perbufylline is a bronchodilator. It is N-methylated xanthine derivative. Perbufylline acts as a competitive antagonist at 5-HT2 and alpha1-adrenoceptors, with at least 100-fold less activity at alpha2-adrenoceptors. | |||
T73970 | |||
Febuxostat dicarboxylic acid impurity 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
T73967 | |||
Febuxostat impurity 7 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
T73971 | |||
Febuxostat amide impurity 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
TN4433 | cAMP HIV Protease Antifection | ||
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase. | |||
TN1503 | NADPH-oxidase | ||
Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.). |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-02464 | Catalase/CAT Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells | ||
Catalase is a ubiquitously expressed enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a tetramer of four polypeptides chains containing four porphyrin heme groups that allow the enzyme to react with the hydrogen peroxide. The optimum PH of human catalase is approximately 7 and the optimum temperature is at 37 degree. Both the PH optimum and temperature for other catalases varies depending on the species. Catalase can be inhibited by a flux of O2-generated in situ by the aerobic xanthine oxidase reaction. This inhibition of catalase by O2-provides the basis for a synergism between superoxide dismutase and catalase.Such synergisms have been observed in vitro and may be significant in vivo. Catalase is used in the food industry for removing hydrogen peroxide from milk prior to cheese production. Another use is in food wrappers where it prevents food from oxidizing. Catalase is also used in the textile industry, removing hydrogen peroxide from fabrics to make sure the material is peroxide-free.
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TMPJ-00764 | Catalase/CAT Protein, Human, Recombinant | Human | E. coli | ||
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells, and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of catalase activity in red cells and is associated with ulcerating oral lesions.
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