目录号 | 产品详情 | 靶点 | |
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TN1503 | NADPH-oxidase | ||
Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide anion radical (O2-.). | |||
T11270 | Others | ||
Febuxostat D9 is deuterium labeled Febuxostat, which is a selective xanthine oxidase inhibitor with Ki of 0.6 nM. | |||
T73965 | |||
Febuxostat n-butyl isomer 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
T73969 | |||
Febuxostat impurity 6 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
T73960 | |||
Febuxostat isopropyl isomer 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
T73968 | |||
Febuxostat impurity 8 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂,Ki 为 0.6 nM。 | |||
T26710 | |||
Azapropazone is anti-inflammatory agent. Azapropazone has uricosuric properties used to treat rheumatoid arthritis and ankylosing spondylitis. Azapropazone lowered plasma uric acid but exerted only a modest and variable uricosuric effect without altering | |||
T75949 | |||
NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1), with an inhibition concentration (IC50) of 20 nM, demonstrating selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits NOX1-derived O2- production in HT-29 human colon cancer cells and attenuates VEGF-induced migration of human pulmonary artery endothelial cells under hypoxic conditions in vitro. | |||
T69281 | |||
Febuxostat 67M-4 is a derivative compound of Febuxostat 67M-1 which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and reduces the risk of gout or kidney stone formation. | |||
TN3473 | |||
Axillarin has antioxidant activity, it shows xanthine oxidase inhibitory activity ( IC(50) :36.0 uM). Axillarin can strongly protect primary cultured neurons against glutamate-induced oxidative stress. |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-02464 | Catalase/CAT Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells | ||
Catalase is a ubiquitously expressed enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a tetramer of four polypeptides chains containing four porphyrin heme groups that allow the enzyme to react with the hydrogen peroxide. The optimum PH of human catalase is approximately 7 and the optimum temperature is at 37 degree. Both the PH optimum and temperature for other catalases varies depending on the species. Catalase can be inhibited by a flux of O2-generated in situ by the aerobic xanthine oxidase reaction. This inhibition of catalase by O2-provides the basis for a synergism between superoxide dismutase and catalase.Such synergisms have been observed in vitro and may be significant in vivo. Catalase is used in the food industry for removing hydrogen peroxide from milk prior to cheese production. Another use is in food wrappers where it prevents food from oxidizing. Catalase is also used in the textile industry, removing hydrogen peroxide from fabrics to make sure the material is peroxide-free.
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TMPJ-00764 | Catalase/CAT Protein, Human, Recombinant | Human | E. coli | ||
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells, and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of catalase activity in red cells and is associated with ulcerating oral lesions.
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