T37480
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NPC-15437 (盐酸盐) 是一种 PKC 的选择性抑制剂,与酶的调节域相互作用。 |
T31042
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CP-195543 is an effective leukotriene B4 antagonist for the treatment of inflammatory diseases. |
T71579
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GOE-5438 is a calcium antagonist that has been shown to inhibit the excitation and contraction of single cardiomyocytes. |
T24036
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WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor. |
T23354
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Others
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Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor |
T25826
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MMV024101 is a PI4K inhibitor. MMV024101 exhibits submicromolar potency against P. falciparum NF54 (IC50 =543 nM), low aqueous solubility (<5 μM), and rapid clearance by mouse liver microsomes with only 2% of parent compound remaining after 30 min of incu |
T75381
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Bodipy TMR-X muscimol为标记有Bodipy的Muscimol(Ex=543 nm, Em=572 nm),是GABAA受体的激动剂。该化合物适用于可视化可逆脑失活的扩散研究。 |
T37472
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TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide. Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-residue protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease. Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers. TAMRA-Amyloid-β (1-42) peptide is a labeled form of Aβ42 containing carboxytetramethyl rhodamine (TAMRA), which displays excitation/emission maxima of 543/572 nm, respectively. |
T36836
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(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2
1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988) |