目录号 | 产品详情 | 靶点 | |
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TN2600 | Others | ||
12-Hydroxysapriparaquinone is a natural product from Salvia prionitis. | |||
TMIH-0328 | |||
Menaquinone 4-d7 (Mixture of cis-trans isomers) 是 Menaquinone 4 (Mixture of cis-trans isomers) 的氘代化合物。 | |||
T64376 | NADPH | ||
Casein kinase 1δ-IN-9是一种醌还原酶2(Quinone reductase 2)抑制剂,IC50为0.6μM。 | |||
T77640 | Calcium Channel | ||
ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate 对 NAD(P)H:醌氧化还原酶 1 具有抑制作用。 | |||
T7149 | NADPH Autophagy | ||
S29434 是一种竞争性、选择性和可透过细胞膜的醌还原酶 2 抑制剂,对人 QR2 的 IC50值为 5-16 nM。它可诱导自噬,抑制 QR2 介导的 ROS 的产生。 | |||
T2906 | VEGFR | ||
Tanshinone IIA (Tanshinone B) 是红根丹参根系中的一种主要组合物。它能够利用靶向 VEGF/VEGFR2的蛋白激酶结构域,抑制血管生成。 | |||
TD0104 | Others | ||
Methyl purple 是一种引入的醌-酰亚胺氧化还原染料,已被证明是一种对叶绿体中光系统 I 活性异常敏感的监测器。 | |||
TN5845 | Antioxidant HBV | ||
Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) 来源于毛蒿和黑色苦莓(Aronia melanocarpa)果实。Neochlorogenic acid methyl ester 显示出抗 HBV 活性、抗氧化活性和醌还原酶活性,CD 为 6.7 μM。 | |||
T8347 | Reactive Oxygen Species ROS Antibacterial Antibiotic | ||
Rifamycin S 是一种 DNA 依赖性 RNA 聚合酶抑制剂,是一种醌和一种针对革兰氏阳性细菌的抗生素试剂。它是涉及两个电子的可逆氧化还原系统的氧化形式。它能产生活性氧并抑制微粒体脂质过氧化,可研究肺结核和麻风病。 | |||
T14953 | Antibiotic | ||
Chloroquinoxaline sulfonamide (Chloroquinoxaline) 是 sulfaquinoxaline 的结构类似物,是在饮用水和地表水中经常被检测到低水平的有机微污染物。Chloroquinoxaline sulfonamide 具有抗菌活性,可抑制大鼠肝微粒体在体外对维生素K环氧化物和维生素K醌的二硫苏糖醇依赖性还原。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPH-01225 | DHODH Protein, Human, Recombinant (His) | Human | E. coli | ||
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
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TMPY-03407 | NQO1 Protein, Human, Recombinant (His) | Human | E. coli | ||
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Recent pharmacological research suggests the feasibility of genotype-directed redox chemotherapeutic intervention targeting NQO1 breast cancer, a common missense genotype encoding a functionally impaired NQO1 protein.
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TMPH-02850 | DHODH Protein, Mouse, Recombinant (His) | Mouse | E. coli | ||
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
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TMPH-02627 | DHODH Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli | ||
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
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TMPH-03278 | DHODH Protein, Rat, Recombinant (His) | Rat | E. coli | ||
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
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TMPH-00098 | AtAER Protein, Arabidopsis thaliana, Recombinant | Arabidopsis thaliana | E. coli | ||
AtAER Protein, Arabidopsis thaliana, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 38.1 kDa and the accession number is Q39172.
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TMPH-00097 | AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO) | Arabidopsis thaliana | E. coli | ||
AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is Q39172.
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TMPH-02269 | Tyrosinase/TYR Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) | ||
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
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TMPH-02270 | Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO) | Human | E. coli | ||
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
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TMPH-02882 | NQO2 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) | ||
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
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TMPH-02797 | NQO1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) | ||
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q64669.
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