T71631
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Eucatropine,作为一种有效的毒蕈碱型乙酰胆碱受体(mAChR)抑制剂,具有0.583 μM的IC50值,归类为抗胆碱能剂。 |
T69336
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NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist. |
T28181
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NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR. |
T13129
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AChR
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Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively). |
T61878
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N-Demethyl MK-6884 (compound 34) is an influential allosteric modulator of the M4 mAChR, which finds applicability in Alzheimer's disease research as well as the study of other diseases influenced by the M4 mAChR [1]. |
T62218
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Parapenzolate bromide 是一种口服具有活力的 mAChR 拮抗剂。Parapenzolate bromide 是一种抗胆碱能剂,也是一种解痉挛剂。 |
T61228
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Pirenzepine (LS 519 free base) is a selective antagonist of the M1 muscarinic acetylcholine receptor (mAChR). It effectively inhibits gastric acid secretion and reduces muscle spasm, making it a valuable compound for investigating peptic ulcers. Additionally, Pirenzepine exhibits anti-proliferative activity against cancer cells [1] [2]. |
T16417
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AChR
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Oxitropium bromide is a mAChR antagonist. It is used as an anticholinergic bronchodilator drug for the treatment of asthma and chronic obstructive pulmonary disease. |
T75586
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Dendraspis Angusticeps Venom(Eastern Green Mamba Venom)是从Dendraspis Angusticeps(绿曼巴蛇)中提取的蛇毒,其含有利钠肽和成束蛋白(抗胆碱酯酶毒素)。这种毒液能够增强乙酰胆碱的释放,并抑制苯甲酸奎宁环与毒蕈碱乙酰胆碱受体(mAChR)的结合。 |
T60577
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Cycrimine 是毒蕈碱胆碱能受体(mAChR)M1的口服活性拮抗剂,可降低帕金森模型中乙酰胆碱的水平。Cycrimine 具有解痉活性,可用于研究行为和精神障碍。 |