T23797
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Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and carcinogenic activity. |
T0051
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Chloride channel
GABA Receptor
Antibacterial
GluR
NMDAR
AChR
Parasite
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Urethane (Ethylurethane) 是多种食品中发酵形成的副产物,是氨基甲酸的乙酯,具有抑制细菌、海胆卵、原生动物和植物组织生长的作用。 |
T4169
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Others
DNA Alkylator/Crosslinker
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N-Nitroso-N-methylurea (Methylnitrosourea) 是一种具有烷基化、致癌和致突变特性的亚硝基脲化合物。它靶向多种动物器官,可引起各种癌症和变性疾病,可用于重氮甲烷合成。 |
T4918
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Reductase
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DL-Glyceraldehyde (Glyceric aldehyde) 是由酶甘油醛脱氢酶的作用产生的,该酶使用 NADP 作为辅因子将甘油转化为甘油醛。它是一种高活性化合物,可以修饰和交联蛋白质。 |
T0289
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Others
HIV Protease
Antibacterial
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9-Aminoacridine 是一种具有龋齿传播特性的抗菌剂,可用作局部消毒剂。它也是一种高度荧光染料,实验用作一种诱变剂,是细胞内 pH 的指示剂。 |
T21280
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Aminacrine hydrochloride monohydrate, a highly fluorescent anti-infective dye, is used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator. |
T26728
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Aziridyl benzoquinone, an antineoplastic agent, has been studied as a mutagen and as a carcinogenic agent. |
T31027
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CP 67015 has an inhibitory effect on the function of topoisomerase, and is a direct mutagen in mammalian cells, which has effects on gene and chromosome levels. |
TN3403
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Immunology/Inflammation related
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Djalonensone (Alternariol monomethyl ether) 具有强大的 DPPH 自由基清除作用。 |
T37031
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Autophagy
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Quinacrine mustard hydrochloride 是一种荧光染料,也 是一种多环芳香剂,可作为诱变剂诱导细菌的突变体。Quinacrine mustard hydrochloride 能选择性地与腺嘌呤-胸腺嘧啶(AT)碱基对结合,而不 是与鸟嘌呤-胞嘧啶(GC)碱基对结合,诱导细胞周期停滞在 G2/M 期。Quinacrine mustard (hydrochloride) 已被用于标记移相染色体,以通过自动放射摄影技术进行核型分析。 |