T33314
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Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil |
TN3926
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Others
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Eicosanyl caffeate has anti-ulcer and moderate antioxidant properties, it exhibits potent elastase inhibitory activity, with the IC(50) value of 0.99 microg/mL. |
T73653
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Pexiganan(MSI 78 free base),maganin 2 的合成类似物,是一种具有口服活性的广谱强效抗菌肽,主要用于研究糖尿病足溃疡等相关感染。 |
T71980
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Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton pump inhibitor and as such blocks the release of stomach acid. |
TN4322
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ATPase
Potassium Channel
GABA Receptor
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Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GABAA receptors and to antioxidant properties.Isopulegol presents significant gastroprotective effects in both ethanol- and indomethacin-induced ulcer models, which appear to be mediated, at least in part, by endogenous prostaglandins, K(ATP) channel opening, and antioxidant properties. |
T78510
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Others
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Zolimidine是一种咪唑并吡啶衍生物,可作为口服抗溃疡剂。它能刺激肠粘膜细胞分泌粘液,增强肠壁的抗溃疡能力,并在十二指肠溃疡研究中显示出胃保护效果。 |
TN4223
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Antifection
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Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property |
TMIH-0602
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Vonoprazan-d4 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。 |
T78218
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Proton pump
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Ilaprazole (IY-81149) sodium hydrate是一种具有口服活性的质子泵抑制剂,可以量依赖性地不可逆抑制H+/K+-ATPase,并在兔壁细胞制剂中展示出IC50为6μM的效力。该化合物主要用于胃溃疡的研究,并已证实是一种有效的T细胞起源蛋白激酶(TOPK)抑制剂。 |
TMIH-0601
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Vonoprazan-d3 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。 |