目录号 | 产品详情 | 靶点 | |
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T78218 | Proton pump | ||
Ilaprazole (IY-81149) sodium hydrate是一种具有口服活性的质子泵抑制剂,可以量依赖性地不可逆抑制H+/K+-ATPase,并在兔壁细胞制剂中展示出IC50为6μM的效力。该化合物主要用于胃溃疡的研究,并已证实是一种有效的T细胞起源蛋白激酶(TOPK)抑制剂。 | |||
T36454 | |||
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis. Levels of 1-stearoyl-rac-glycerol are decreased in lung tissue from patients with adenocarcinoma, but are increased in the serum of patients with Buruli ulcer and in the cerebrospinal fluid of patients with the inflammatory demyelinating diseases multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and idiopathic transverse myelitis (ITM). 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart. | |||
T61643 | |||
Vonoprazan hydrochloride 是一种高效且具口服活性的质子泵抑制剂 (PPI) 和钾竞争性酸阻断剂 (potassium-competitive acid blocker, P-CAB),展示出优秀的抗分泌活性。在 pH 为 6.5 的条件下,该化合物可抑制猪胃微粒体内 H+,K+-ATPase 的酶活性,呈现出 19 nM 的 IC50 值。Vonoprazan hydrochloride 主要应用于胃酸相关疾病的研究,包括胃食管反流病和消化性溃疡,并可用于根除幽门螺杆菌。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-00749 | FGF-2 Protein, Human, Recombinant | Human | E. coli | ||
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.bFGF/FGF2 Protein & Antibody Products
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TMPY-00210 | FGF-2 Protein, Mouse, Recombinant (His) | Mouse | E. coli | ||
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.bFGF/FGF2 Protein & Antibody Products
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TMPY-06900 | HSV 2 (strain HG52) Glycoprotein E/gE Protein (His) | HSV2 | Baculovirus-Insect Cells | ||
Herpes simplex virus type 2 (HSV-2) is the predominant cause of genital ulcer disease in human. Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to immune evasion by HSV.
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