目录号 | 产品详情 | 靶点 | |
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T21916 | |||
TC-SP 14, also known as compound 14, is a highly active and potent S1P1 agonist with oral bioavailability. It exhibits an EC50 value of 0.042 μM, indicating its strong binding affinity to the S1P1 receptor. Notably, its interaction with the S1P3 receptor is minimal, as evidenced by an EC50 value of 3.47 μM. TC-SP 14 demonstrates significant pharmacological effects, including a marked reduction in blood lymphocyte counts and the attenuation of delayed type hypersensitivity response to antigen challenge [1]. | |||
T79977 | |||
Maceneolignan A,一种可从肉豆蔻(肉豆蔻科)假种皮分离的天然产品,有能力抑制RBL-2H3细胞内β-己糖胺酶释放,其IC50值为48.4 μM。同样,Maceneolignan A对抗原激活的RBL-2H3细胞中TNF-α释放的抑制作用,其IC50为63.7 μM。 | |||
T78310 | |||
Raxibacumab (ABthrax)是针对炭疽杆菌(Bacillus anthracis)保护性抗原(PA)的人类IgG1型单克隆抗体。该抗体能够防止保护性抗原与宿主细胞受体结合,有效阻断炭疽毒素的有毒效应,用于炭疽病防治研究。 | |||
T35668 | |||
Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50 = 13 μM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50 = 1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s = 34.3, 47, and 37.2 μg/ml, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50 = 0.84 μg/ml) and increases survival of P. densiflora trees inoculated with B. xylophilus. | |||
T75567 | |||
Cabenoside D(化合物 8)是从苔藓根的甲醇提取物中分离的一种三萜苷,显示出对12-O-十四烷酰基激素-13-乙酸酯(TPA)诱导的小鼠炎症的抗炎活性,并能抑制TPA促使的Epstein-Barr病毒(EBV)早期抗原(EBV-EA)激活。 | |||
T76638 | |||
IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate 作为一种干扰素 γ (IFN-γ) 拮抗剂,能够在 Colo 205 细胞中抑制 IFN-γ诱导的 HLR/DR 抗原表达,其 IC50 值约为 35 μM,显示出在免疫调节中的潜在应用价值。 | |||
T78290 | |||
Obiltoxaximab是一款针对炭疽保护抗原(PA)的高效单克隆抗体。它在阻断炭疽毒素组装及其对靶细胞的毒害中发挥关键作用。此外,Obiltoxaximab也适用于进行吸入性炭疽感染动物模型到人类剂量转换的研究。 | |||
T73220 | |||
RO5461111 是一种高特异性、口服有效的Cathepsin S 拮抗剂 (IC50: 0.4 nM, humanCathepsin S ; 0.5 nM, murineCathepsin S)。RO5461111 能够有效抑制抗原特异性 T 细胞和 B 细胞活化。RO5461111 对肺部炎症和狼疮性肾炎有改善作用。 | |||
T83121 | |||
Anatumomab mafenatox (ABR-214936)是一种73 KDa的重组蛋白,针对广泛表达于恶性肿瘤中的肿瘤相关抗原5T4。该分子构建于修饰后的SEA和小鼠Fab片段之间。Anatumomab mafenatox的主要副作用包括发烧、低血压、疼痛、恶心和嗜睡。 | |||
TN4592 | IL Receptor TNF COX Prostaglandin Receptor | ||
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line, |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-02698 | CD14 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CD14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P08571.
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TMPH-03640 | 34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) | Treponema pallidum | E. coli | ||
This antigen is a pathogen-specific membrane immunogen. 34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.1 kDa and the accession number is P19478.
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TMPY-05850 | CEACAM6 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells | ||
CEACAM6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.3 kDa and the accession number is XP_005589488.1.
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TMPY-00971 | CEACAM6 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CEACAM6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is P40199.
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TMPY-05050 | CEACAM5 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells | ||
CEACAM5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.5 kDa and the accession number is XP_005589491.1.
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TMPY-03235 | BST2 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
BST2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q10589.
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TMPY-01180 | CD86 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
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TMPY-00369 | LY6D Protein, Human, Recombinant (mFc) | Human | HEK293 Cells | ||
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane proteins and applies to various biological phenomena in situations in which both target molecule-expressing cells and nonexpressing cells are available. Diseases associated with LY6D include Alzheimer's Disease 16 and Inferior Myocardial Infarction.
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TMPY-01647 | CEACAM5 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CEACAM5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 72.8 kDa and the accession number is A0A024R0K5.
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TMPY-00322 | DEC-205 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s and OV2008), by directing epithelial-to-mesenchymal transition (EMT) associated with reduced capacity for in vivo EOC cell colonization, as similar/identical signaling pathways were reversely regulated, when compared to mesenchymal LY75 knockdown EOC cells. Diseases associated with LY75 include Pneumonic Plague and Adenoiditis.
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TMPJ-00103 | CD28 Protein, Human/Cynomolgus, Recombinant (His) | Human,Cynomolgus | HEK293 Cells | ||
CD28 Protein, Human/Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is P10747.
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TMPJ-00211 | CD47 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is Q08722.
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TMPY-02709 | P-Selectin Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
P-Selectin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.4 kDa and the accession number is AAN06828.1.
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TMPY-04123 | CEACAM1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells | ||
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
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TMPY-01850 | CEACAM3 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. Monoclonal antibodies grouped in the CD66 cluster recognize CEACAM members. Ectopic CD66 expression is commonly detected in B-cell lineage acute lymphoblastic leukemia (ALL). CEACAM3 mediates phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3. CEACAM3 is characterized by rapid stimulation of the GTPase Rac.
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TMPJ-00113 | CD79B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells | ||
CD79B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-65 KDa and the accession number is P40259.
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TMPY-00381 | PSMA Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
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TMPY-00476 | ITGB1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer.
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TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
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TMPY-03562 | CD86 Protein, Cynomolgus, Rhesus, Recombinant (hFc) | Cynomolgus,Rhesus | HEK293 Cells | ||
CD86 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q9BDM4.
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TMPY-02016 | CD86 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells | ||
CD86 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A9K3Y6P6.
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TMPY-03646 | CD86 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 Cells | ||
CD86 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9BDM4.
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TMPY-00697 | CD14 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells | ||
CD14 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.4 kDa and the accession number is P08571.
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TMPJ-01242 | CD160 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
CD160 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-25 KDa and the accession number is Q8VC80.
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TMPH-03724 | F1 capsule antigen Protein, Yersinia pestis, Recombinant (His) | Yersinia pestis | P. pastoris (Yeast) | ||
F1 capsule antigen Protein, Yersinia pestis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.6 kDa and the accession number is P26948.
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TMPJ-00329 | CD19 Protein, Rhesus macaque, Recombinant (hFc) | Rhesus | HEK293 Cells | ||
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
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TMPH-03763 | Major egg antigen Protein, Schistosoma mansoni, Recombinant (His) | Schistosoma mansoni | E. coli | ||
Major egg antigen Protein, Schistosoma mansoni, Recombinant (His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 43.4 kDa. Accession number: P12812
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TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells | ||
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328.
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TMPJ-00627 | CD160 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells | ||
CD160 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16-30 KDa and the accession number is G7MG20.
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TMPJ-00626 | CD160 Protein, Rhesus macaque, Recombinant (hFc) | Rhesus | HEK293 Cells | ||
CD160 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is G7MG20.
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TMPH-01048 | CEACAM5 Protein, Human, Recombinant (E398K, His) | Human | HEK293 Cells | ||
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.; (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 Protein, Human, Recombinant (E398K, His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 74.1 kDa and the accession number is P06731.
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TMPJ-00959 | B7-2 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells | ||
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
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TMPH-02990 | Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (His) | Mycobacterium bovis | Baculovirus Insect Cells | ||
Acts as a chaperone. Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (His) is expressed in Baculovirus insect cells with C-9xHis tag. The predicted molecular weight is 18.1 kDa and the accession number is P0A5B8.
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TMPH-02991 | Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (E. coli, His) | Mycobacterium bovis | E. coli | ||
Acts as a chaperone. Alpha-crystallin Protein, Mycobacterium bovis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.1 kDa and the accession number is P0A5B8.
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TMPK-01385 | CRTAM Protein, Canine, Recombinant (His) | Canine | HEK293 Cells | ||
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.19 kDa and the accession number is E2QWY2.
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TMPK-00971 | CRTAM Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.1 kDa and the accession number is Q149L7-1.
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TMPH-02571 | CD9 Protein, Mouse, Recombinant (His) | Mouse | E. coli | ||
Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption. Acts as a receptor for PSG17. Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Also regulates integrin-dependent migration of macrophages, particularly relevant for inflammatory response in the lung.
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TMPH-03526 | Cap8A Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | E. coli | ||
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Cap8A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is O15479.
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TMPJ-00958 | B7-1 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells | ||
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response.
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TMPY-06710 | PSCA Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
PSCA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.83 kDa and the accession number is P57096.
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TMPY-03737 | Thy1/CD90 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells | ||
Thy1/CD90 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.9 kDa.
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TMPJ-00630 | B7-1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells | ||
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.
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TMPY-06655 | PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells | ||
PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 11.64 kDa and the accession number is P57096.
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TMPY-03165 | Thy1/CD90 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells | ||
Thy1/CD90 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.1 kDa and the accession number is P01830.
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TMPJ-00632 | B7-2 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells | ||
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession number is G7NXR4.
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TMPJ-00130 | SLAMF2 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells | ||
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.
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TMPJ-00641 | B7-2 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells | ||
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the accession number is H9ZFI8.
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TMPJ-00588 | CEACAM7 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) is a member of the immunoglobulin superfamily A and CEA family. CEACAM7 localizes to the cell membrane and contains one Ig-like C2-type domain and one Ig-like V-type domain. The expression of CEACAM7 is significantly decreased in rectal cancer. Differences in CEACAM7 expression levels between long-term survivors and those with recurrent disease introduce a potential tumor marker to define a subset of patients who benefit most from adjuvant therapy.
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TMPY-02543 | PCNA Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells | ||
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replicating forks during S phase and (ii) a soluble form in quiescent cells in G1 and G2 phases. PCNA forms a toroidal trimer in S phase with replication factor-C (RF-C) and DNA in an ATP-dependent manner and enables the loading of DNA polymerase delta and epsilon onto the complex. The close association of PCNA with kinase complexes involved in cell cycle machinery indicates that PCNA has a regulatory role in cell cycle progression. PCNA also participates in the processing of branched intermediates that arise during the lagging strand DNA synthesis.
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TMPJ-00850 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) | Mouse | HEK293 Cells | ||
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
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