B7-2 Protein, Cynomolgus, Recombinant (hFc)

T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

规格	价格/CNY		数量
10 μg	￥ 440	5日内发货
50 μg	￥ 1,340	5日内发货
500 μg	￥ 11,000	5日内发货
1 mg	￥ 15,800	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 440

5日内发货

50 μg

￥ 1,340

5日内发货

500 μg

￥ 11,000

5日内发货

1 mg

￥ 15,800

5日内发货

产品描述

种属	Cynomolgus
表达系统	Human Cells
标签	C-Fc
蛋白编号	G7NXR4
别名	T-lymphocyte activation antigen CD86 isoform 1, Activation B7-2 antigen, CD86
氨基酸序列	Ala19-His240
蛋白构建	Recombinant Cynomolgus T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Ala19-His240 is expressed with a human IgG1 Fc tag at the C-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	70-100 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

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B7-2 Protein, Cynomolgus, Recombinant (hFc)

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