目录号 | 产品详情 | 靶点 | |
---|---|---|---|
T25985 | |||
Prifelone (R 830) 是一种非甾体抗炎化合物,具有抗氧化活性。 | |||
T19679 | COX | ||
Benoxaprofen (NSC-299582) 是长效的、强效的抗炎和解热化合物,在体外具有较弱的对环氧合酶的抑制作用,也可以抑制脂氧合酶,在一些炎症动物模型中抑制单核细胞迁移。 | |||
T27209 | Others | ||
Droxicam (Droxicamum) 是一种非甾体抗炎化合物,可用于缓解肌肉骨骼疾病的炎症和疼痛的研究。 | |||
T0184 | COX | ||
Fenoprofen calcium dihydrate 是一种丙酸衍生物,用作非甾体抗炎剂。 | |||
T14546 | Others | ||
Bermoprofen (AD-1590) 是一种口服活性非甾体抗炎化合物, 具有抗炎镇痛活性,可用于研究胃溃疡。 | |||
T6498 | Apoptosis Others COX | ||
Fenoprofen calcium hydrate (Progesic dihydrate) 是一非甾体类抗炎症化合物。 | |||
T7389 | Estrogen Receptor/ERR | ||
G15 是一种高亲和力的、选择性的 G 蛋白偶联雌激素受体(GPER/GPR30)拮抗剂(Ki:20 nM)。 | |||
T7313 | Estrogen Receptor/ERR | ||
Enclomiphene citrate (trans-Clomiphene citrate) 是口服具有活力的 oestrogen receptor 拮抗剂,具有抗雌激素活性。 | |||
T11340 | Prostaglandin Receptor | ||
Furprofen, a non-steroidal anti-inflammatory drug (NSAID), exerts its effects by inhibiting the synthesis of prostaglandin (PGE). This compound demonstrates analgesic properties and can be conveniently administered orally to alleviate pain. | |||
T6540 | COX | ||
Ibuprofen Lysine (Neoprofen) 是一种非甾体抗炎药。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
---|---|---|---|---|---|
TMPH-01640 | MRGPRX2 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system | ||
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.
|