非甾体类抗炎化合物库

Nonsteroidal Anti-Inflammatory Compound Library

产品编号： L4710

非甾体抗炎药（Nonsteroidal Antiinflammatory Drugs，NSAIDs）是一类不含皮质激素甾体结构的抗炎药，NSAIDs 自阿司匹林于1898年首次合成后，100多年来已有百余种上千个品牌上市，这类药物包括阿司匹林、对乙酰氨基酚、吲哚美辛、萘普生、萘普酮、双氯芬酸、布洛芬、尼美舒利、罗非昔布、塞来昔布等，该类药物通过抑制环氧化酶、减少前列腺素的合成，从而发挥抗炎、抗风湿、止痛、退热和抗凝血等作用，在临床上广泛用于骨关节炎、类风湿性关节炎、多种发热和各种疼痛症状的缓解。

TargetMol 非甾体类抗炎化合物库收集了530 种非甾体类的抗炎相关化合物，可用于抗炎相关的药理研究和药物开发。

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产品规格

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

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产品描述

530种非甾体类的抗炎相关化合物，可用于高通量和高内涵筛选；
包含常见非甾体抗炎药活性成分，如阿司匹林、吲哚美辛、舒林酸、布洛芬、吡罗昔康等；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR和HPLC技术保证产品高纯度。

化合物库定制

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化合物库组成

COX (144)

Apoptosis (72)

Histamine Receptor (72)

Autophagy (54)

Antibacterial (45)

Endogenous Metabolite (36)

IL Receptor (28)

NF-κB (27)

Reactive Oxygen Species (26)

Antibiotic (23)

ROS (22)

Antiviral (18)

TLR (18)

NOS (17)

Parasite (17)

TNF (17)

Influenza Virus (16)

Interleukin (15)

CXCR (14)

Adrenergic Receptor (12)

Antifungal (12)

CCR (12)

HIV Protease (12)

5-HT Receptor (11)

Ferroptosis (11)

MRP (11)

Virus Protease (11)

Antioxidant (10)

Prostaglandin Receptor (10)

AhR (9)

JAK (9)

P450 (9)

Potassium Channel (9)

Aryl Hydrocarbon Receptor (8)

Dopamine Receptor (8)

Lipoxygenase (8)

LTR (8)

NO Synthase (8)

PPAR (8)

AChR (7)

DNA/RNA Synthesis (7)

IRAK (7)

NOD (7)

Nrf2 (7)

PGE Synthase (7)

Mitophagy (6)

NOD-like Receptor (NLR) (6)

Norepinephrine (6)

PDE (6)

SARS-CoV (6)

STING (6)

ERK (5)

HCV Protease (5)

NADPH (5)

Phospholipase (5)

Tyrosine Kinases (5)

Xanthine Oxidase (5)

Calcium Channel (4)

Dehydrogenase (4)

HBV (4)

IκB/IKK (4)

Leukotriene Receptor (4)

MMP (4)

p38 MAPK (4)

Sodium Channel (4)

STAT (4)

AMPK (3)

Cell wall (3)

Chloride channel (3)

Drug Metabolite (3)

Glutathione Peroxidase (3)

HIF (3)

HSV (3)

IFNAR (3)

iGluR (3)

NADPH-oxidase (3)

Opioid Receptor (3)

Retinoid Receptor (3)

Wnt/beta-catenin (3)

ABC (2)

Adenosine Receptor (2)

Akt (2)

ALK (2)

Aminopeptidase (2)

Antifection (2)

ATPase (2)

BTK (2)

CaMK (2)

DNA (2)

Estrogen Receptor/ERR (2)

FGFR (2)

Gap Junction Protein (2)

HSP (2)

MAO (2)

PD-1/PD-L1 (2)

Proteasome (2)

RAAS (2)

ribosome (2)

Topoisomerase (2)

transporter (2)

TRP/TRPV Channel (2)

VEGFR (2)

AChE (1)

Acyltransferase (1)

Amino Acids and Derivatives (1)

Anion Exchanger (1)

Antifolate (1)

Anti-infection (1)

Aromatase (1)

BCL (1)

Beta Amyloid (1)

Caspase (1)

CAT (1)

CDK (1)

Chk (1)

Cysteine Protease (1)

DNA Alkylator/Crosslinker (1)

Epigenetic Reader Domain (1)

Estrogen/progestogen Receptor (1)

FAAH (1)

Factor Xa (1)

FAK (1)

FLAP (1)

Free radical scavengers (1)

Galectin (1)

Gamma-secretase (1)

gp120/CD4 (1)

GPR (1)

HDAC (1)

HER (1)

HIF/HIF Prolyl-Hydroxylase (1)

Histone Acetyltransferase (1)

Histone Methyltransferase (1)

Hydroxylase (1)

IAP (1)

Immunology/Inflammation related (1)

Integrin (1)

JNK (1)

Lipase (1)

MALT (1)

MAPK (1)

MEK (1)

Microtubule Associated (1)

Mitochondrial Metabolism (1)

Monoamine Oxidase (1)

Monoamine Transporter (1)

Monocarboxylate transporter (1)

N-Acetylglucosaminyltransferase (1)

NMDAR (1)

NPC1L1 (1)

Nucleoside Antimetabolite/Analog (1)

PAFR (1)

PAI-1 (1)

PARP (1)

P-gp (1)

Phosphatase (1)

PI3K (1)

Platelet aggregation (1)

Progesterone Receptor (1)

Protease-activated Receptor (1)

Proton pump (1)

Raf (1)

Ras (1)

Reductase (1)

RIP kinase (1)

ROCK (1)

RSV (1)

S6 Kinase (1)

Serine Protease (1)

SIK (1)

Sirtuin (1)

Src (1)

Syk (1)

Telomerase (1)

TGF-beta/Smad (1)

Thrombin (1)

Transferase (1)

Trk receptor (1)

Tyrosinase (1)

UGT (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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