目录号 | 产品详情 | 靶点 | |
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T6876 | Glucagon Receptor | ||
Liraglutide (Liraglutida) 是胰高血糖素样肽-1 受体激动剂,用于 2 型糖尿病的研究。 | |||
T72621 | |||
GCGR antagonist2 是一种呋喃-2-碳酰肼化合物,是具有口服活性的胰高血糖素受体拮抗剂。GCGR antagonist2 与 hGluR 结合的 Kd 值为 2.3 nM,抑制大鼠受体的 IC50值为 0.43 nM。GCGR antagonist2 可抑制胰高血糖素刺激的糖原分解。 | |||
TP1469 | Glucagon Receptor | ||
Lixisenatide acetate 是一种胰高血糖素样肽 1 受体的激动剂,可用于研究 2 型糖尿病。 | |||
TQ0239 | Glucagon Receptor | ||
PF-06291874 (Glucagon receptor antagonists-4) 是口服有活性的胰高血糖素受体非肽类拮抗剂。它正用于研究 2 型糖尿病。 | |||
TP2100 | Glucagon Receptor | ||
Avexitide (Exendin-3 (9-39) amide) 是一种特异竞争性的glucagon-like peptide-1 (GLP-1)受体拮抗剂。 | |||
TP1376 | Others Glucagon Receptor | ||
GLP-1(7-37) acetate 是肠道胰岛素激素,能够促进葡萄糖诱导的胰岛素分泌。 | |||
T15389L | Glucocorticoid Receptor Glucagon Receptor | ||
Glucagon (1-29), bovine, human, porcine hydrochloride 是一种由胰腺 α 细胞产生的多肽激素。它可激活 HNF4α 并促进 HNF4α 磷酸化,促进糖异生。 | |||
T60047 | Glucagon Receptor | ||
V-0219 是 GLP-1 的正变构调节剂,可用于肥胖相关糖尿病的研究。 | |||
T9579 | Glucagon Receptor | ||
1H-Benzimidazole-6-carboxylic acid 是GLP-1 receptor 激动剂。 | |||
T3984 | Glucagon Receptor | ||
GLP-1(7-36), amide (MKC 253) 是一种生理性肠降血糖素,能够刺激胰岛素分泌。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPH-02675 | GCGR Protein, Mouse, Recombinant (GST) | Mouse | E. coli | ||
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
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TMPH-01383 | GCGR Protein, Human, Recombinant (His & Myc) | Human | HEK293 | ||
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
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TMPH-01382 | GCGR Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli | ||
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
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