目录号 | 产品详情 | 靶点 | |
---|---|---|---|
T72901 | |||
Indolokine A5, L-半胱氨酸的分解代谢物, 是一种有效的AhR 激动剂。 | |||
T72430 | |||
L-Kynurenine sulfate 是一种芳香烃受体AHR 激动剂,可激活 AHR 导向的初始T 细胞极化至抗炎 Treg 表型。 | |||
T13981 | Others | ||
β-Naphthoflavone-CH2-Br is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br used to synthesize the PROTAC β-NF-JQ1. | |||
T24960 | |||
10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR). | |||
T25235 | |||
CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR). | |||
T16082 | Others | ||
Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent. | |||
T17363 | Others | ||
β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) serves as an AhR E3 ligase ligand, forming chimeric molecules when connected to a protein ligand through a linker, resulting in PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1). These chimeric molecules recruit the AhR E3 ligase complex by incorporating AhR ligands. By inducing ubiquitination-mediated degradation, PROTACs effectively target and degrade cancer-promoting proteins [1]. | |||
T12771 | Leukotriene Receptor Thrombin | ||
RS-601 是一种有效的 leukotriene D4/thromboxane A2 双重抑制剂,对抗原诱导的气道高反应性 (AHR)有抑制作用且在豚鼠哮喘模型中显示出平喘作用。 | |||
T22725 | Others | ||
DiMNF is a selective aryl hydrocarbon receptor (AHR) modulator. It also suppresses the expression of CD55 and CD46 induced by IL-1β in an inflammatory tumor cell microenvironment. | |||
T28878 | |||
Sul-121 has anti-oxidative capacity. In experimental chronic obstructive pulmonary disease (COPD) models, Sul-121 HCl inhibits airway inflammation and hyperresponsiveness (AHR) prospectively through inhibition of oxidative stress. |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
---|---|---|---|---|---|
TMPH-00958 | AHR Protein, Human, Recombinant (His) | Human | E. coli | ||
AHR Protein, Human, Recombinant (His) is expressed in E. coli.
|
|||||
TMPJ-00423 | TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.
|