目录号 | 产品详情 | 靶点 | |
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T14506 | Others Adenosine Receptor | ||
BAY 60-6583 是一种强效、高亲和力的腺苷 A2B 受体激动剂(EC50 = 3 nM),对A2B 受体的亲和力超过对 A1、A2A 和 A3 受体的亲和力。BAY 60-6583 在心肌缺血模型中具有心脏保护作用。BAY 60-6583 与小鼠、兔子和狗 A2BAR 的结合 Ki 值分别为 750 nM、340 nM 和 330 nM。 | |||
T26842 | |||
Bms 188107 is a calcium antagonist, it has cardioprotective effects. | |||
T28656 | |||
Sabiporide is a NHE-1 inhibitor and a cardioprotective agent. | |||
T69097 | |||
ARD-353 is a nonpeptide delta receptor agonist with cardioprotective effects. | |||
T12709 | Others | ||
Resveratrol analog 2 is an analog of Resveratrol. Resveratrol is a natural polyphenolic phytoalexin with possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. | |||
TN1412 | IL Receptor Others | ||
Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production. | |||
T40586 | |||
Neophytadiene, a diterpene discovered in Turbinaria ornate, showcases desirable bioactive properties including anti-inflammatory, antioxidant, and cardioprotective effects. | |||
T12708 | Others | ||
Resveratrol analog 1 is an analog of Resveratrol. Resveratrol is a natural polyphenolic phytoalexin with possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. | |||
T30487 | |||
BMS 180448 is a prototype mitochondrial ATP-sensitive K+ (Mitok (ATP)) channel opener with cardioprotective and vasodilating properties. | |||
T31191 | |||
Dagapamil hydrochloride 是一种钙通道阻滞剂。Dagapamil hydrochloride 在动物模型中具有降压、抗心律失常、心脏保护、抗过敏和抑制血小板聚集的作用。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPJ-00734 | KNG1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Kininogen-1 is a secreted protein which contains three cystatin domains. There are two alternatively spliced forms, designated as the high molecular weight (HMW) and low MW (LMW) forms. Kininogen-1 plays a critical role in blood coagulation and inflammatory response. Kininogens are inhibitors of thiol proteases. Kininogen-1 participates in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, also inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from Kininogen-1 shows a variety of physiological effects: influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, decrease in blood glucose level. It is a mediator of inflammation and causes increase in vascular permeability, stimulation of nociceptors release of other mediators of inflammation. It has a cardioprotective effect. LMW-kininogen inhibits the aggregation of thrombocytes and doesn’t involved in blood clotting.
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TMPY-01606 | Kininogen 1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells | ||
Kininogen 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.5 kDa and the accession number is D3YTY9.
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TMPY-01598 | Kininogen 1 Protein, Human, Recombinant (His) | Human | HEK293 Cells | ||
Kininogen 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is P01042-1.
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