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肿瘤坏死因子家族

肿瘤坏死因子 (Tumor Necrosis Factor family, TNFs) 超家族是 II 型跨膜蛋白的蛋白质超家族,含有 TNF 同源结构域并形成三聚体。TNFs的成员可以通过细胞外蛋白水解裂解从细胞膜中释放出来,并作为细胞因子发挥作用。这些蛋白质主要由免疫细胞表达,它们调节多种细胞功能,包括免疫反应和炎症,以及增殖、分化、凋亡和胚胎发生。TNFs包含 19 个成员,与 TNF 受体超家族的 29 个成员结合。肿瘤坏死因子受体超家族(Tumor necrosis factor receptor superfamily, TNFRSF)是细胞因子受体的蛋白质超家族,其特征在于能够通过富含细胞外半胱氨酸的结构域结合TNF。TNFs的 PROSITE 模式位于蛋白质中央部分的 β 折叠中,该折叠在所有成员中都是保守的。

目录号 产品名/同用名 种属 表达系统
TMPK-00591 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) Mouse HEK293 Cells
TMPK-00666 CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
TMPK-00716 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244) Human HEK293 Cells
TMPK-00717 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
TMPK-00727 TNFSF12/TWEAK Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPK-00860 CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc) Mouse HEK293 Cells
TMPK-01011 TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293 Cells
TMPK-01012 TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
TMPK-01013 TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPK-01064 GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPK-01163 APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag) Mouse HEK293 Cells
TMPK-01349 APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag) Cynomolgus HEK293 Cells
TMPJ-01472 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (Flag & His) Mouse HEK293 Cells
TMPK-01398 CD40 Ligand Trimer Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-00248 Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) Cynomolgus Baculovirus Insect Cells
TMPY-00537 RANKL/TNFSF11/CD254 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
TMPY-00584 TWEAK/TNFSF12 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
TMPY-00618 BAFF/TNFSF13B Protein, Canine, Recombinant (hFc) Canine HEK293 Cells
TMPY-00959 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
TMPY-01239 BAFF/TNFSF13B Protein, Human, Recombinant (hFc) Human HEK293 Cells
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