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Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

产品编号 TMPY-00248
别名: Lymphotoxin β, lymphotoxin β (TNF superfamily, member 3), lymphotoxin beta (TNF superfamily, member 3)

LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.

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Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
50 μg ¥ 2,940 5日内发货
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产品目录号及名称: Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) (TMPY-00248)
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产品描述 LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.
种属 Cynomolgus
表达系统 Baculovirus-Insect Cells
标签 His
蛋白编号 XP_003897389.1
别名 Lymphotoxin β, lymphotoxin β (TNF superfamily, member 3), lymphotoxin beta (TNF superfamily, member 3)
蛋白构建 A DNA sequence encoding the cynomolgus LTB (XP_003897389.1) (Gln49-Gly244) was expressed with a polyhistidine tag at the N-terminus.
蛋白纯度 > 90 % as determined by SDS-PAGE.
分子量 22.8 kDa (predicted)
内毒素 < 1.0 EU per μg protein as determined by the LAL method.
缓冲液 Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.

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Keywords

Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) TNF superfamily, member 3 Lymphotoxin β lymphotoxin beta lymphotoxin β (TNF superfamily, member 3) lymphotoxin beta (TNF superfamily, member 3) recombinant recombinant-proteins proteins protein

 

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