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肿瘤坏死因子家族

肿瘤坏死因子 (Tumor Necrosis Factor family, TNFs) 超家族是 II 型跨膜蛋白的蛋白质超家族,含有 TNF 同源结构域并形成三聚体。TNFs的成员可以通过细胞外蛋白水解裂解从细胞膜中释放出来,并作为细胞因子发挥作用。这些蛋白质主要由免疫细胞表达,它们调节多种细胞功能,包括免疫反应和炎症,以及增殖、分化、凋亡和胚胎发生。TNFs包含 19 个成员,与 TNF 受体超家族的 29 个成员结合。肿瘤坏死因子受体超家族(Tumor necrosis factor receptor superfamily, TNFRSF)是细胞因子受体的蛋白质超家族,其特征在于能够通过富含细胞外半胱氨酸的结构域结合TNF。TNFs的 PROSITE 模式位于蛋白质中央部分的 β 折叠中,该折叠在所有成员中都是保守的。

目录号 产品名/同用名 种属 表达系统
TMPY-03875 OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (mFc) Cynomolgus HEK293 Cells
TMPY-04065 CD40 Ligand Protein, Canine, Recombinant (mFc) Canine HEK293 Cells
TMPY-04086 CD40 Ligand Protein, Canine, Recombinant Canine HEK293 Cells
TMPY-04331 LIGHT/TNFSF14 Protein, Human, Recombinant (His) Human HEK293 Cells
TMPY-04354 OX40L/TNFSF4 Protein, Human, Recombinant (mFc) Human HEK293 Cells
TMPY-04581 CD30L Protein, Human, Recombinant Human HEK293 Cells
TMPY-04587 Fas Ligand Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
TMPY-04819 LIGHT/TNFSF14 Protein, Human, Recombinant (hFc) Human HEK293 Cells
TMPY-04833 LIGHT/TNFSF14 Protein, Human, Recombinant (rFc) Human HEK293 Cells
TMPY-04843 LIGHT/TNFSF14 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
TMPY-04913 Fas Ligand Protein, Rat, Recombinant (His) Rat P. pastoris (Yeast)
TMPY-04978 TL1A/TNFSF15 Protein, Human, Recombinant (rFc) Human HEK293 Cells
TMPY-04979 TL1A/TNFSF15 Protein, Human, Recombinant (mFc) Human HEK293 Cells
TMPY-04980 OX40L/TNFSF4 Protein, Mouse, Recombinant (rFc) Mouse HEK293 Cells
TMPY-04981 OX40L/TNFSF4 Protein, Mouse, Recombinant (mFc) Mouse HEK293 Cells
TMPY-05041 TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc) Mouse HEK293 Cells
TMPY-05163 GITRL Protein, Human, Recombinant (mFc) Human HEK293 Cells
TMPY-05173 4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
TMPY-05187 TNF alpha Protein, Mouse, Recombinant, Biotinylated Mouse E. coli
TMPY-05237 TNF alpha Protein, Human, Recombinant, Biotinylated Human E. coli
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