T80549
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CaMK
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Myristoylated Calmodulin Kinase IINtide(Myr-CaMKIINtide)是一种选择性非竞争性CaMKII抑制剂。 |
T26673
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AT-076 is a noncompetitive antagonist of the κ-opioid receptor (Ki = 1.14 nM) and nociceptin receptor (Ki = 1.75 nM) and a competitive antagonist of the μ-opioid receptor (Ki = 1.67 nM) and δ-opioid receptor (Ki = 19.6 nM). |
T75886
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[Ala107]MBP(104-118) TFA 为针对protein kinase C (PKC)的非竞争性肽抑制剂,IC50值介于46-145 μM之间。 |
T80710
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Glucosidase
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α-Glucosidase-IN-40 (compound 5)是一款非竞争性α-glucosidase抑制剂,其半抑制浓度(IC50)为24.62 μM。 |
T61344
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VO-OHPic is a reversible, noncompetitive, and selective inhibitor of PTEN with an IC50 of 46 nM. It effectively attenuates apoptosis, adverse cardiac remodeling, and the presence of pro-inflammatory M1 macrophages in models of doxorubicin-induced cardiomyopathy. Additionally, VO-OHPic inhibits autophagy [1] [2] [3]. |
T68959
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Fenobam hydrate is a noncompetitive antagonist and inverse agonist of metabotropic glutamate receptor 5 (mGluR5). It inhibits intracellular calcium mobilization induced by the glutamate analog quisqualate and inhibits basal activity of mGluR5. Fenobam reduces stress-induced hyperthermia, exhibits anxiolytic-like activity, and may induce analgesia. |
T69378
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Homidium Free Base is a trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide. |
T38241
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2-Aminoimidazole is a potent antibiofilm agent and adjuvant to antimicrobial treatments, which effectively disrupts bacterial self-protection mechanisms by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. Additionally, 2-Aminoimidazole acts as a weak noncompetitive inhibitor of human arginase I, with a Ki value of 3.6 mM[1][2][3]. |
T21875
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CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity. It effectively counters the Kainate-induced response in rat cortical neurons, exhibiting an IC 50 of 25 nM. As such, CP-465022 Maleate presents a valuable instrument for studying the involvement of AMPA receptors in various physiological and pathophysiological processes [1] [2]. |
TP1961L
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Proteasome
Antibacterial
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PR 39 (porcine) acetate 是一种非竞争性、可逆的变构蛋白酶体抑制剂。 它可逆地与蛋白酶体的 α7 亚基结合,并通过泛素-蛋白酶体途径阻断 NF-κB 抑制剂 IκBα 的降解。 |