目录号 | 产品详情 | 靶点 | |
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T10152L | COX | ||
4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak anti-inflammatory properties. | |||
T12336 | Others | ||
Oxaprozin D4 is the deuterium labeled Oxaprozin, is a non-steroidal anti-inflammatory drug (NSAID). | |||
T61261 | |||
Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) known for its potent inhibition of prostaglandin-synthetase. This compound exhibits notable anti-inflammatory and antipyretic properties [1] [2]. | |||
T68027 | |||
CP-461是一种口服生物有效的第二代选择性凋亡抗肿瘤化合物(SAAND)和非甾体抗炎化合物(NSAID)舒林酸的类似物,具有潜在的促凋亡和抗肿瘤活性。 | |||
T72146 | |||
Loxoprofenol-SRS tromethamine (HR1405-01) 为Loxoprofen的活性代谢物,为一种可静脉注射的安全非甾体抗炎药(NSAID),展现出良好的抗炎及镇痛效果。 | |||
T68563 | |||
Piroxicam olamine is a cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily. | |||
T37117 | |||
Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A9, UGT1A10, and UGT2B7. 1.Kutsuno, Y., Itoh, T., Tukey, R.H., et al.Glucuronidation of drugs and drug-induced toxicity in humanized UDP-glucuronosyltransferase 1 miceDrug Metab. Dispos.42(7)1146-1152(2014) | |||
T36538 | |||
NO-indomethacin is a hybrid molecule of indomethacin and a nitric oxide (NO) donor. This drug design combines the anti-inflammatory properties of a non-steroidal anti-inflammatory drug (NSAID) with the gastrointestinal protective effects of NO. Compounds of this class retain their anti-inflammatory and analgesic activity, but have reduced gastrointestinal and kidney toxicity compared to the NSAID alone. NO-indomethacin also enhances the cancer chemopreventative activity of indomethacin. NO-indomethacin exhibits an IC50 of 82 μM, compared to >1,000 μM for indomethacin alone, for the inhibition of pancreatic cancer cell (PaCa-2) growth after 24 hours in culture. | |||
T12047 | Others | ||
Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers. | |||
T2550L | |||
Tolmetin sodium dihydrate, a non-steroidal anti-inflammatory drug (NSAID), is a potent and orally active inhibitor of COX (cyclooxygenase). Its IC 50 values for human COX-1 and COX-2 are 0.35 μM and 0.82 μM, respectively [1] [2]. |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPK-01243 | GDF-15 Protein, Rat, Recombinant (His) | Rat | E. coli | ||
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
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TMPK-00569 | GDF-15 Protein, Canine, Recombinant (His) | Canine | E. coli | ||
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6.
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TMPK-00196 | GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | E. coli | ||
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession number is Q99988-1.
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